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The map label for this gene is ligC

Identifier: 41406439

GI number: 41406439

Start: 366577

End: 367686

Strand: Direct

Name: ligC

Synonym: MAP0341

Alternate gene names: 41406439

Gene position: 366577-367686 (Clockwise)

Preceding gene: 41406435

Following gene: 41406441

Centisome position: 7.59

GC content: 68.83

Gene sequence:

>1110_bases
ATGGACCTTCCTGTCATGCCGCCGGTGTCGCCGATGCTGGCGAAGTCGGTCGGCGCGATTCCCCCGGCCGCGTCGTATGA
GCCCAAGTGGGACGGCTTCCGGTCGATCTGTTTCCGCGACGGCGACGAGGTCGAGTTGGGCAGCCGCAACGAGCGGCCGA
TGACGCGCTACTTCCCCGAATTGGTGGCGGCGGTGCGGGCGGAGCTGCCGCAGCGCTGCGTGATCGACGGGGAGATCGTC
ATCGCCACCGACCACGGCCTGGACTTCGAGGCGCTGCAACAACGCGTCCATCCGGCCGAGTCGCGGGTGCGGATGCTGGC
CGAGGCCACGCCGGCGTCGTTCATCGCCTTCGACCTGCTGGCGCTGGGCGACGAGGACTACACCGGCCGGCCGTTCCGCG
AGCGGCGCGCGGCGCTGCTGGAGGCGGTGGGCGGTCCGGGGCCCTCGATCCATGTCACGCCGGCGACCACCGATCTGGAC
ACCGCGCGGCGGTGGTTCGACGAATTCGAGGGCGCCGGGCTCGACGGTGTGGTCGCCAAGCCGTTGGACATCACGTATCA
GCCGGACAAGCGGGTGATGTTCAAGATCAAACACGAGCGGACGGCCGACTGTGTGGTGGCCGGTTATCGGGTGCACAAGT
CCGGGGCGGACGCGATCGGCTCGTTGTTGCTGGGGCTGTATCAGGATGACGGCCAGCTCGCGTCGGTCGGCGTGATCGGC
GCCTTCCCGATGGCCGAGCGGCGGCGGCTGTTCACCGAATTACAGCCGCTGGTCACCGATTTCGAGGACCACCCGTGGAA
CTGGGCCGCGCACCAGGCCGGCGAGCGCACGCCCCGCAAGAACGAGTTCTCGCGCTGGAACGCCGGCAAGGACCTCTCGT
TCGTCCCGCTGCGGCCCGAGCGGGTGGTCGAGGTCCGCTATGACCACATGGAGGGCCGGCGATTCCGTCATACCGCGCAG
TTCAATCGATGGCGGCCGGACCGCGACCCACGCTCCTGCACCTACGAACAGCTCGAGCAGCCGGTGACGTTTCGCCTGGA
CGACATCGTGCCGGGCCTCGGCGCGAGCCGCGCAGATCACAAGCCCGGCAAGCAGATTGGGGCTCCATAG

Upstream 100 bases:

>100_bases
GGGAAATACACCTTGTCCGGATTTGTCAGACGGACCGCGATGCCGTCGACGTCGACCTCTTCTGCAGCAGCCATACCTCC
GATTCCAGCACAATCGGGCT

Downstream 100 bases:

>100_bases
CACGGCGGCCCGCCGAGCGGCTGCCGGGGAGCGTCCCCCTCCCAGACGAATTGGCCGACGTTGCCCATGCCGCCGACGGG
AACCCAGTACCAGTGGTGGC

Product: ATP-dependent DNA ligase

Products: NA

Alternate protein names: Polydeoxyribonucleotide synthase [ATP] [H]

Number of amino acids: Translated: 369; Mature: 369

Protein sequence:

>369_residues
MDLPVMPPVSPMLAKSVGAIPPAASYEPKWDGFRSICFRDGDEVELGSRNERPMTRYFPELVAAVRAELPQRCVIDGEIV
IATDHGLDFEALQQRVHPAESRVRMLAEATPASFIAFDLLALGDEDYTGRPFRERRAALLEAVGGPGPSIHVTPATTDLD
TARRWFDEFEGAGLDGVVAKPLDITYQPDKRVMFKIKHERTADCVVAGYRVHKSGADAIGSLLLGLYQDDGQLASVGVIG
AFPMAERRRLFTELQPLVTDFEDHPWNWAAHQAGERTPRKNEFSRWNAGKDLSFVPLRPERVVEVRYDHMEGRRFRHTAQ
FNRWRPDRDPRSCTYEQLEQPVTFRLDDIVPGLGASRADHKPGKQIGAP

Sequences:

>Translated_369_residues
MDLPVMPPVSPMLAKSVGAIPPAASYEPKWDGFRSICFRDGDEVELGSRNERPMTRYFPELVAAVRAELPQRCVIDGEIV
IATDHGLDFEALQQRVHPAESRVRMLAEATPASFIAFDLLALGDEDYTGRPFRERRAALLEAVGGPGPSIHVTPATTDLD
TARRWFDEFEGAGLDGVVAKPLDITYQPDKRVMFKIKHERTADCVVAGYRVHKSGADAIGSLLLGLYQDDGQLASVGVIG
AFPMAERRRLFTELQPLVTDFEDHPWNWAAHQAGERTPRKNEFSRWNAGKDLSFVPLRPERVVEVRYDHMEGRRFRHTAQ
FNRWRPDRDPRSCTYEQLEQPVTFRLDDIVPGLGASRADHKPGKQIGAP
>Mature_369_residues
MDLPVMPPVSPMLAKSVGAIPPAASYEPKWDGFRSICFRDGDEVELGSRNERPMTRYFPELVAAVRAELPQRCVIDGEIV
IATDHGLDFEALQQRVHPAESRVRMLAEATPASFIAFDLLALGDEDYTGRPFRERRAALLEAVGGPGPSIHVTPATTDLD
TARRWFDEFEGAGLDGVVAKPLDITYQPDKRVMFKIKHERTADCVVAGYRVHKSGADAIGSLLLGLYQDDGQLASVGVIG
AFPMAERRRLFTELQPLVTDFEDHPWNWAAHQAGERTPRKNEFSRWNAGKDLSFVPLRPERVVEVRYDHMEGRRFRHTAQ
FNRWRPDRDPRSCTYEQLEQPVTFRLDDIVPGLGASRADHKPGKQIGAP

Specific function: DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair [H]

COG id: COG1793

COG function: function code L; ATP-dependent DNA ligase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATP-dependent DNA ligase family [H]

Homologues:

Organism=Drosophila melanogaster, GI85815841, Length=261, Percent_Identity=30.2681992337165, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022865
- InterPro:   IPR000977
- InterPro:   IPR012309
- InterPro:   IPR012310
- InterPro:   IPR016059
- InterPro:   IPR012308
- InterPro:   IPR012340
- InterPro:   IPR016027 [H]

Pfam domain/function: PF04679 DNA_ligase_A_C; PF01068 DNA_ligase_A_M; PF04675 DNA_ligase_A_N [H]

EC number: =6.5.1.1 [H]

Molecular weight: Translated: 41409; Mature: 41409

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50160 DNA_LIGASE_A3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDLPVMPPVSPMLAKSVGAIPPAASYEPKWDGFRSICFRDGDEVELGSRNERPMTRYFPE
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCCCCHHHHHHH
LVAAVRAELPQRCVIDGEIVIATDHGLDFEALQQRVHPAESRVRMLAEATPASFIAFDLL
HHHHHHHHCCCCEEECCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHH
ALGDEDYTGRPFRERRAALLEAVGGPGPSIHVTPATTDLDTARRWFDEFEGAGLDGVVAK
HCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEC
PLDITYQPDKRVMFKIKHERTADCVVAGYRVHKSGADAIGSLLLGLYQDDGQLASVGVIG
CEEEEECCCCEEEEEECCCCCCCEEEECEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEE
AFPMAERRRLFTELQPLVTDFEDHPWNWAAHQAGERTPRKNEFSRWNAGKDLSFVPLRPE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCEEECCCCH
RVVEVRYDHMEGRRFRHTAQFNRWRPDRDPRSCTYEQLEQPVTFRLDDIVPGLGASRADH
HEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCCCCCCCC
KPGKQIGAP
CCCCCCCCC
>Mature Secondary Structure
MDLPVMPPVSPMLAKSVGAIPPAASYEPKWDGFRSICFRDGDEVELGSRNERPMTRYFPE
CCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCCCEECCCCCCCCHHHHHHH
LVAAVRAELPQRCVIDGEIVIATDHGLDFEALQQRVHPAESRVRMLAEATPASFIAFDLL
HHHHHHHHCCCCEEECCEEEEEECCCCCHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHH
ALGDEDYTGRPFRERRAALLEAVGGPGPSIHVTPATTDLDTARRWFDEFEGAGLDGVVAK
HCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHCCCCCCCEEEC
PLDITYQPDKRVMFKIKHERTADCVVAGYRVHKSGADAIGSLLLGLYQDDGQLASVGVIG
CEEEEECCCCEEEEEECCCCCCCEEEECEEEECCCHHHHHHHHHHHHCCCCCEEEEEEEE
AFPMAERRRLFTELQPLVTDFEDHPWNWAAHQAGERTPRKNEFSRWNAGKDLSFVPLRPE
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCCCCCCCCCHHHCCCCCCCEEECCCCH
RVVEVRYDHMEGRRFRHTAQFNRWRPDRDPRSCTYEQLEQPVTFRLDDIVPGLGASRADH
HEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCEEEHHHHCCCCCCCCCCC
KPGKQIGAP
CCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA