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The map label for this gene is fbpA

Identifier: 41406314

GI number: 41406314

Start: 222993

End: 224036

Strand: Direct

Name: fbpA

Synonym: MAP0216

Alternate gene names: 41406314

Gene position: 222993-224036 (Clockwise)

Preceding gene: 41406313

Following gene: 41406315

Centisome position: 4.62

GC content: 69.73

Gene sequence:

>1044_bases
ATGACGCTTGTCGACAGATTGCGCGGCGCCGTGGCGGGGATGCCGCGCCGGCTCGTGGTGGGGGCCGCTGGTGCGGCGCT
GCTCTCGGGCCTGATTGGCGCCGTCGGGGGCTCGGCGACCGCCGGGGCCTTCTCGCGCCCCGGTCTGCCGGTGGAGTACC
TGCAGGTTCCCTCCGCCGCCATGGGACGGGACATCAAGGTCCAGTTCCAAAGCGGTGGGGCCAACTCGCCCGCGTTGTAC
CTGCTCGACGGGATGCGCGCGCAAGACGACTTCAACGGCTGGGACATCAACACCCCGGCGTTCGAGTGGTACAACCAGTC
GGGCATCTCGGTCGCCATGCCGGTCGGCGGCCAGTCCAGCTTCTACTCCGACTGGTACAAGCCCGCCTGCGGCAAGGCCG
GCTGCACCACCTACAAGTGGGAGACCTTCCTGACCAGCGAGCTGCCGCAGTACCTGTCGGCGCAGAAGCAGGTCAAGCCG
ACCGGCAGCGGTGTCGTCGGCCTGTCGATGGCCGGCTCCTCGGCGCTGATCCTGGCCGCCTACCACCCCGACCAGTTCGT
CTACGCCGGCTCGCTGTCGGCGCTGCTGGACTCGTCGCAGGGCATGGGCCCGTCGCTGATCGGGCTGGCCATGGGTGACG
CCGGTGGCTACAAGGCCGCCGACATGTGGGGTCCGAAGGAGGACCCGGCCTGGGCCCGCAACGACCCGTCGCTGCAGGTC
GGCAAGCTGGTCGCGAACAACACCCGGATCTGGGTGTACTGCGGCAACGGCAAGCCGTCCGACCTCGGTGGCGACAACCT
GCCCGCCAAGTTCCTCGAGGGCTTCGTGCGGACGTCCAACCTGAAGTTCCAGGACGCCTACAACGGCGCCGGCGGCCACA
ACGCGGTGTGGAACTTCGACGCCAACGGCACCCACGACTGGCCCTACTGGGGCGCGCAGCTGCAGGCGATGAAGCCTGAC
CTGCAGTCGGTGCTGGGCGCCACCCCGGGCGCCGGTCCGGCCACGGCCGCGGCCACCAATGCTGGGAACGGCCAGGGCAC
CTAA

Upstream 100 bases:

>100_bases
GCTTCATGCCATCGGTAGGCGCAGGCGGTTCGAACCAATCAAGAAAGCGGCCGAGCGGACGAACGCGCCGGAACGCCGCA
AGAAGGATGAGGAAGCAAGG

Downstream 100 bases:

>100_bases
CCAATACCGAGCATGACGCCGGCGGCGGGAACCCTTCGGGGCTCCCGCCGCCGGTCGTTTCGCGATGGTGTGACGAGTTT
CACTACCCGGCGCGCGGGGG

Product: FbpA

Products: NA

Alternate protein names: Antigen 85 complex A; 85A; Ag85A; Fibronectin-binding protein A; Mycolyl transferase 85A [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLPVEYLQVPSAAMGRDIKVQFQSGGANSPALY
LLDGMRAQDDFNGWDINTPAFEWYNQSGISVAMPVGGQSSFYSDWYKPACGKAGCTTYKWETFLTSELPQYLSAQKQVKP
TGSGVVGLSMAGSSALILAAYHPDQFVYAGSLSALLDSSQGMGPSLIGLAMGDAGGYKAADMWGPKEDPAWARNDPSLQV
GKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNLKFQDAYNGAGGHNAVWNFDANGTHDWPYWGAQLQAMKPD
LQSVLGATPGAGPATAAATNAGNGQGT

Sequences:

>Translated_347_residues
MTLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLPVEYLQVPSAAMGRDIKVQFQSGGANSPALY
LLDGMRAQDDFNGWDINTPAFEWYNQSGISVAMPVGGQSSFYSDWYKPACGKAGCTTYKWETFLTSELPQYLSAQKQVKP
TGSGVVGLSMAGSSALILAAYHPDQFVYAGSLSALLDSSQGMGPSLIGLAMGDAGGYKAADMWGPKEDPAWARNDPSLQV
GKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNLKFQDAYNGAGGHNAVWNFDANGTHDWPYWGAQLQAMKPD
LQSVLGATPGAGPATAAATNAGNGQGT
>Mature_346_residues
TLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLPVEYLQVPSAAMGRDIKVQFQSGGANSPALYL
LDGMRAQDDFNGWDINTPAFEWYNQSGISVAMPVGGQSSFYSDWYKPACGKAGCTTYKWETFLTSELPQYLSAQKQVKPT
GSGVVGLSMAGSSALILAAYHPDQFVYAGSLSALLDSSQGMGPSLIGLAMGDAGGYKAADMWGPKEDPAWARNDPSLQVG
KLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNLKFQDAYNGAGGHNAVWNFDANGTHDWPYWGAQLQAMKPDL
QSVLGATPGAGPATAAATNAGNGQGT

Specific function: Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintain

COG id: COG0627

COG function: function code R; Predicted esterase

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mycobacterial A85 antigen family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000801
- InterPro:   IPR006311 [H]

Pfam domain/function: PF00756 Esterase [H]

EC number: NA

Molecular weight: Translated: 36086; Mature: 35955

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLPVEYLQVPSAA
CCHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHH
MGRDIKVQFQSGGANSPALYLLDGMRAQDDFNGWDINTPAFEWYNQSGISVAMPVGGQSS
HCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCC
FYSDWYKPACGKAGCTTYKWETFLTSELPQYLSAQKQVKPTGSGVVGLSMAGSSALILAA
HHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEE
YHPDQFVYAGSLSALLDSSQGMGPSLIGLAMGDAGGYKAADMWGPKEDPAWARNDPSLQV
ECCCCEEECCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEE
GKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNLKFQDAYNGAGGHNAVWNFD
EEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEC
ANGTHDWPYWGAQLQAMKPDLQSVLGATPGAGPATAAATNAGNGQGT
CCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCHHCCCCCCCCCC
>Mature Secondary Structure 
TLVDRLRGAVAGMPRRLVVGAAGAALLSGLIGAVGGSATAGAFSRPGLPVEYLQVPSAA
CHHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHCCCCHH
MGRDIKVQFQSGGANSPALYLLDGMRAQDDFNGWDINTPAFEWYNQSGISVAMPVGGQSS
HCCEEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCCCCHHHHCCCCCCEEEEECCCCCC
FYSDWYKPACGKAGCTTYKWETFLTSELPQYLSAQKQVKPTGSGVVGLSMAGSSALILAA
HHHHHCCCCCCCCCCCEEEHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEEE
YHPDQFVYAGSLSALLDSSQGMGPSLIGLAMGDAGGYKAADMWGPKEDPAWARNDPSLQV
ECCCCEEECCCHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCEEE
GKLVANNTRIWVYCGNGKPSDLGGDNLPAKFLEGFVRTSNLKFQDAYNGAGGHNAVWNFD
EEEEECCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHCCEEEEECCCCCCCCCCEEEEC
ANGTHDWPYWGAQLQAMKPDLQSVLGATPGAGPATAAATNAGNGQGT
CCCCCCCCCCCCEEEECCHHHHHHHCCCCCCCCCCHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9284137 [H]