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The map label for this gene is mer [H]

Identifier: 41406239

GI number: 41406239

Start: 146827

End: 147870

Strand: Direct

Name: mer [H]

Synonym: MAP0141

Alternate gene names: 41406239

Gene position: 146827-147870 (Clockwise)

Preceding gene: 41406238

Following gene: 41406241

Centisome position: 3.04

GC content: 67.72

Gene sequence:

>1044_bases
GTGACCATGCGGATCGGATTGAGCATCAACTATGCGGGCGGCTTCAAGGACGTGGCCGCCGAGGTGGCCGACCTGGAAAA
CGCCGGGCTGGACATCGTTTTCGTGCCCGAGGCGTACTCGTTCGACGCGGTGAGCGCGCTGGGCTACCTGGCGGCGAGCA
CCCAGCGAGTTGAGCTCGCGTCGGGCATCCTGCAGCTCTACACCCGAACGCCCACCCTGACCGCGATGACCGCGGCCGGC
CTGGACTACGTCTCCGACGGACGGTTCACCCTCGGCCTGGGAGCGTCGGGTCCGCAGGTGATCGAGGGCTTCCACGGCGT
GCCCTACGACGCCCCGATCGGGCGTACCCGCGAAGTGATCGAGATCTGCCGCCAGGTGTGGCGGCGCGAGCCGGTGCAGC
ACCGGGGCAAGCACTACACGATCCCGCTGCCCGCCGACCGGGGAACGGGGCTGGGTAAACCGCTCAAGCTCATCAATTCT
CCTGTCCGCGAACGGATTCCGATTCTAGTGGCCGCGCTGGGGCCCAAGAACGTCGAGATGGCGGCCGAGATCGCCGAGGG
CTGGCAGCCGATCTTCTATCTGCCCGAGAAGGCGCGCGACGTGTGGGGCGAGTCGCTGGCCGCCGGCCGGGCCAAGCGCG
CCGCCGAGTTGGGTGAGCTGGAGATCTACGCCGGCCCGGTATTGGCAATCGGCGAAAACGTGGAGCCGCTAAGGGAATTC
GTCAAACCGCACCTGGCCCTCTACATCGGTGGGATGGGCGCCAAGGGCAAGAACTTCTACCATGCGCTGGCCACCAAGTA
CGGATACGGCCCGCAAGCCGACCGGATCCAGGAGCTCTACCTGGCCGGCGACAAGGACGGGGCGGCCAAGGTGGTGCCGG
ATGATCTGGTGCGCGACGTGAACCTGATCGGCAGCCGGGAGTTCGTCAAGGAGCGGGTGGCGGCGTTCCGGGAGGCCGGG
GTGACCACCCTGAACGTGGCGCCGATGGCGTCCACCCCCGCCGAGCGGGTCAAGCTGATCGAGGCCCTGCGCCAACTGGT
GTGA

Upstream 100 bases:

>100_bases
CGGGTGCGACGGCGTTGTCCGAGGCGATGGGCGCCCAGTTCGCGCGCATCCAGCAGGAGGCGGTCGAATTGGCCAATCGA
TTCGGCACCGCGTAGAAGTA

Downstream 100 bases:

>100_bases
CGCGCGTACCGGGCACGCGCGTCGGCTCGGCGAAATCAGTTCTGCCGGTGGTCATCTCGTCGCAGCCGGGCCGCTCTGCC
GACCGCCGCCGTCATGGCCA

Product: hypothetical protein

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 347; Mature: 346

Protein sequence:

>347_residues
MTMRIGLSINYAGGFKDVAAEVADLENAGLDIVFVPEAYSFDAVSALGYLAASTQRVELASGILQLYTRTPTLTAMTAAG
LDYVSDGRFTLGLGASGPQVIEGFHGVPYDAPIGRTREVIEICRQVWRREPVQHRGKHYTIPLPADRGTGLGKPLKLINS
PVRERIPILVAALGPKNVEMAAEIAEGWQPIFYLPEKARDVWGESLAAGRAKRAAELGELEIYAGPVLAIGENVEPLREF
VKPHLALYIGGMGAKGKNFYHALATKYGYGPQADRIQELYLAGDKDGAAKVVPDDLVRDVNLIGSREFVKERVAAFREAG
VTTLNVAPMASTPAERVKLIEALRQLV

Sequences:

>Translated_347_residues
MTMRIGLSINYAGGFKDVAAEVADLENAGLDIVFVPEAYSFDAVSALGYLAASTQRVELASGILQLYTRTPTLTAMTAAG
LDYVSDGRFTLGLGASGPQVIEGFHGVPYDAPIGRTREVIEICRQVWRREPVQHRGKHYTIPLPADRGTGLGKPLKLINS
PVRERIPILVAALGPKNVEMAAEIAEGWQPIFYLPEKARDVWGESLAAGRAKRAAELGELEIYAGPVLAIGENVEPLREF
VKPHLALYIGGMGAKGKNFYHALATKYGYGPQADRIQELYLAGDKDGAAKVVPDDLVRDVNLIGSREFVKERVAAFREAG
VTTLNVAPMASTPAERVKLIEALRQLV
>Mature_346_residues
TMRIGLSINYAGGFKDVAAEVADLENAGLDIVFVPEAYSFDAVSALGYLAASTQRVELASGILQLYTRTPTLTAMTAAGL
DYVSDGRFTLGLGASGPQVIEGFHGVPYDAPIGRTREVIEICRQVWRREPVQHRGKHYTIPLPADRGTGLGKPLKLINSP
VRERIPILVAALGPKNVEMAAEIAEGWQPIFYLPEKARDVWGESLAAGRAKRAAELGELEIYAGPVLAIGENVEPLREFV
KPHLALYIGGMGAKGKNFYHALATKYGYGPQADRIQELYLAGDKDGAAKVVPDDLVRDVNLIGSREFVKERVAAFREAGV
TTLNVAPMASTPAERVKLIEALRQLV

Specific function: Catalyzes the oxidation of methyl-H(4)MPT to methylene- H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 37538; Mature: 37406

Theoretical pI: Translated: 6.70; Mature: 6.70

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTMRIGLSINYAGGFKDVAAEVADLENAGLDIVFVPEAYSFDAVSALGYLAASTQRVELA
CEEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHHHH
SGILQLYTRTPTLTAMTAAGLDYVSDGRFTLGLGASGPQVIEGFHGVPYDAPIGRTREVI
HHHHHHHHCCCCHHHHHHHCCCEECCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHH
EICRQVWRREPVQHRGKHYTIPLPADRGTGLGKPLKLINSPVRERIPILVAALGPKNVEM
HHHHHHHHCCCHHHCCCEEEEECCCCCCCCCCCHHHHHCCCHHHHCCEEEEECCCCCHHH
AAEIAEGWQPIFYLPEKARDVWGESLAAGRAKRAAELGELEIYAGPVLAIGENVEPLREF
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHH
VKPHLALYIGGMGAKGKNFYHALATKYGYGPQADRIQELYLAGDKDGAAKVVPDDLVRDV
HCHHEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHEECCCCCCCCCCCHHHHHHH
NLIGSREFVKERVAAFREAGVTTLNVAPMASTPAERVKLIEALRQLV
HHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHC
>Mature Secondary Structure 
TMRIGLSINYAGGFKDVAAEVADLENAGLDIVFVPEAYSFDAVSALGYLAASTQRVELA
EEEEEEEEECCCCHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHCCHHHHHH
SGILQLYTRTPTLTAMTAAGLDYVSDGRFTLGLGASGPQVIEGFHGVPYDAPIGRTREVI
HHHHHHHHCCCCHHHHHHHCCCEECCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCHHHH
EICRQVWRREPVQHRGKHYTIPLPADRGTGLGKPLKLINSPVRERIPILVAALGPKNVEM
HHHHHHHHCCCHHHCCCEEEEECCCCCCCCCCCHHHHHCCCHHHHCCEEEEECCCCCHHH
AAEIAEGWQPIFYLPEKARDVWGESLAAGRAKRAAELGELEIYAGPVLAIGENVEPLREF
HHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCHHHHHH
VKPHLALYIGGMGAKGKNFYHALATKYGYGPQADRIQELYLAGDKDGAAKVVPDDLVRDV
HCHHEEEEECCCCCCCCHHHHHHHHHCCCCCCHHHHHHHHEECCCCCCCCCCCHHHHHHH
NLIGSREFVKERVAAFREAGVTTLNVAPMASTPAERVKLIEALRQLV
HHCCCHHHHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9389475 [H]