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The map label for this gene is pabA

Identifier: 41406113

GI number: 41406113

Start: 16008

End: 16694

Strand: Direct

Name: pabA

Synonym: MAP0015

Alternate gene names: 41406113

Gene position: 16008-16694 (Clockwise)

Preceding gene: 41406112

Following gene: 41406123

Centisome position: 0.33

GC content: 69.0

Gene sequence:

>687_bases
ATGCGGATCCTGGTTGTCGACAACTACGACAGCTTCGTGTTCAACCTGGTGCAGTACCTCGGGCAACTGGGTGTGGACGC
CGACGTCTGGCGCAACGACGACAGCCGGCTCGCCGACCACAACGCCGAGGCCCGCCGGTTCGACGGGGTGCTGCTCAGTC
CCGGGCCGGGCACCCCCGAGCGCGCGGGCGCTTCCATCGCGATGGTGCGCGCCTGCGCCGCCGAGCACACCCCGCTGCTG
GGGGTCTGCCTGGGCCACCAGGCCATCGGCGTGGCATTCGGCGCCACCGTGGACCGCGCTCCGGAACTGCTGCACGGCAA
GACCAGCAGCGTGCGCCACACGAATGCCGGTGTGCTGCAAGGGCTTCCGGACCCCTTCACGGCCACCCGGTACCACTCGC
TGACCATCCTGCCCGAGTCGCTGCCGCCGGTGCTCGAGGTCACCGCTCACACCGACAGCGGTGTGATCATGGGCGTGCGC
CACACGCAGTTACCGATCCACGGCGTCCAGTTCCACCCGGAGTCGATCCTGACCGAGGGTGGTCATCGCATGCTGGCGAA
CTGGCTCACCGAATGCGGCTGGGTGCGCGACGACACCCTGGTGCGCCGGCTGGAAAACGACGTCCACGCCGCGGTGCGAC
CGTATCTCCCGGCCGATCCGGCCGCTACTGACCGAACTTCAGCGTGA

Upstream 100 bases:

>100_bases
CGAGCCCGACCGGCTGCATTTCGCCCAGCCCAACGGCCCGATCGGCTACTAACGCCGACTGACCTGCGGCGCGAGCGTCC
GCGGGCGGTAACCTGGCACG

Downstream 100 bases:

>100_bases
TGATCCCGTCCCGGTTGACCCCGGCCCCGGCCGGCGGGTTCTGATACACCACCCGGTGGGACTGGGCGCCGCCGGCGTCG
ACGTCGGGACCCTTGTCCAG

Product: para-aminobenzoate synthase component II

Products: NA

Alternate protein names: Anthranilate synthase component II; Glutamine amido-transferase [H]

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAEARRFDGVLLSPGPGTPERAGASIAMVRACAAEHTPLL
GVCLGHQAIGVAFGATVDRAPELLHGKTSSVRHTNAGVLQGLPDPFTATRYHSLTILPESLPPVLEVTAHTDSGVIMGVR
HTQLPIHGVQFHPESILTEGGHRMLANWLTECGWVRDDTLVRRLENDVHAAVRPYLPADPAATDRTSA

Sequences:

>Translated_228_residues
MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAEARRFDGVLLSPGPGTPERAGASIAMVRACAAEHTPLL
GVCLGHQAIGVAFGATVDRAPELLHGKTSSVRHTNAGVLQGLPDPFTATRYHSLTILPESLPPVLEVTAHTDSGVIMGVR
HTQLPIHGVQFHPESILTEGGHRMLANWLTECGWVRDDTLVRRLENDVHAAVRPYLPADPAATDRTSA
>Mature_228_residues
MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAEARRFDGVLLSPGPGTPERAGASIAMVRACAAEHTPLL
GVCLGHQAIGVAFGATVDRAPELLHGKTSSVRHTNAGVLQGLPDPFTATRYHSLTILPESLPPVLEVTAHTDSGVIMGVR
HTQLPIHGVQFHPESILTEGGHRMLANWLTECGWVRDDTLVRRLENDVHAAVRPYLPADPAATDRTSA

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=186, Percent_Identity=29.0322580645161, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI1789760, Length=187, Percent_Identity=52.4064171122995, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1787517, Length=193, Percent_Identity=39.8963730569948, Blast_Score=127, Evalue=5e-31,
Organism=Saccharomyces cerevisiae, GI6322638, Length=192, Percent_Identity=44.2708333333333, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6324361, Length=214, Percent_Identity=30.3738317757009, Blast_Score=85, Evalue=9e-18,
Organism=Saccharomyces cerevisiae, GI6324878, Length=171, Percent_Identity=29.8245614035088, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 24700; Mature: 24700

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAEARRFDGVLLSPGPGTPE
CEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCHHHHCCEEECCCCCCHH
RAGASIAMVRACAAEHTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVRHTNAGVLQ
HCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCHHHCHHHHCCCCCCCEECCCHHHC
GLPDPFTATRYHSLTILPESLPPVLEVTAHTDSGVIMGVRHTQLPIHGVQFHPESILTEG
CCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEECHHHHHHCC
GHRMLANWLTECGWVRDDTLVRRLENDVHAAVRPYLPADPAATDRTSA
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRILVVDNYDSFVFNLVQYLGQLGVDADVWRNDDSRLADHNAEARRFDGVLLSPGPGTPE
CEEEEEECCHHHHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCHHHHCCEEECCCCCCHH
RAGASIAMVRACAAEHTPLLGVCLGHQAIGVAFGATVDRAPELLHGKTSSVRHTNAGVLQ
HCCCHHHHHHHHHHCCCCEEEEECCCHHHHHHHCCCHHHCHHHHCCCCCCCEECCCHHHC
GLPDPFTATRYHSLTILPESLPPVLEVTAHTDSGVIMGVRHTQLPIHGVQFHPESILTEG
CCCCCCCCCEEEEEEEECCCCCCEEEEEEECCCCEEEEEEECCCCCCCEEECHHHHHHCC
GHRMLANWLTECGWVRDDTLVRRLENDVHAAVRPYLPADPAATDRTSA
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]