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The map label for this gene is gcvR [C]

Identifier: 39998546

GI number: 39998546

Start: 3803900

End: 3804457

Strand: Reverse

Name: gcvR [C]

Synonym: GSU3457

Alternate gene names: 39998546

Gene position: 3804457-3803900 (Counterclockwise)

Preceding gene: 308513346

Following gene: 39998545

Centisome position: 99.75

GC content: 60.22

Gene sequence:

>558_bases
ATGACCAAGGATTCAGTTGTCCACTTCGCCCTTTCCGTCGTCGGCAAGGACCGGCCCGGCATCGTCGCCGGGACTACCGG
CATTCTCTACCGACTCGGCTGCAACATCGAGGACTCCAGCTCCACCATGCTGGGAGGGGAGTTCGCCATGATCCTCATCA
TCTCCCACCCCAAGCCGTTCACCAAGAGCAGGCTGCTCGAAGAATTCCGGGTGCTTGGCGAGGATATGGGCCTCACCGTC
TCCGCCCGTACAATGACCCCCGACGAGGCCGAGTACCGCGCCCCCGAAGGGGAAATCTGCATGCTGTCGGTCTACGGGTC
GGACAAGCCGGGCATCGTCTACCGGGTGACCAAGGAGCTGGCCGAGCGCAGCATCAATATCACCGACCTCAACACAAAGT
TGGTAGGGAAAAAAGGTGAACCGGTCTATGTGATGATGATCGAGGCCGCGCTGCCGGAGGGGATCTCGGTGGACCAGGTG
TCGGCCATGCTCGAAGAAATCAGGAAGGAGCTGAACGTGGAGATCTCGGTGCGCTCAATCACACCGGTTTCCCTCTGA

Upstream 100 bases:

>100_bases
CTCGGGTAGCCGGTCTTGCCATGGCCTCCCGCATCTGCTATAGATTAATGAACCAAATCGGCAGACACTTTTGCCGGGCA
TCGACCCCGGGAGGCACACC

Downstream 100 bases:

>100_bases
CGCCATGCCAGCACAGACCATACTGCAGTATCCCCATCCCGTCCTGAAGAAGGTATGTCATACTGTCACGGCCATCGACG
AGGCCATCAGGGGGCTGATC

Product: glycine cleavage system transcriptional repressor

Products: NA

Alternate protein names: ACT Domain-Containing Protein; Glycine Cleavage System Regulatory Protein; ACT Domain Protein

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MTKDSVVHFALSVVGKDRPGIVAGTTGILYRLGCNIEDSSSTMLGGEFAMILIISHPKPFTKSRLLEEFRVLGEDMGLTV
SARTMTPDEAEYRAPEGEICMLSVYGSDKPGIVYRVTKELAERSINITDLNTKLVGKKGEPVYVMMIEAALPEGISVDQV
SAMLEEIRKELNVEISVRSITPVSL

Sequences:

>Translated_185_residues
MTKDSVVHFALSVVGKDRPGIVAGTTGILYRLGCNIEDSSSTMLGGEFAMILIISHPKPFTKSRLLEEFRVLGEDMGLTV
SARTMTPDEAEYRAPEGEICMLSVYGSDKPGIVYRVTKELAERSINITDLNTKLVGKKGEPVYVMMIEAALPEGISVDQV
SAMLEEIRKELNVEISVRSITPVSL
>Mature_184_residues
TKDSVVHFALSVVGKDRPGIVAGTTGILYRLGCNIEDSSSTMLGGEFAMILIISHPKPFTKSRLLEEFRVLGEDMGLTVS
ARTMTPDEAEYRAPEGEICMLSVYGSDKPGIVYRVTKELAERSINITDLNTKLVGKKGEPVYVMMIEAALPEGISVDQVS
AMLEEIRKELNVEISVRSITPVSL

Specific function: Negative Transcriptional Regulator Of The Glycine Cleavage System Operon (Gcv). Does Not Autoregulate Its Own Expression. It Is Not Yet Known How Gcvr Acts As A Repressor. It Does Not Seem To Bind DNA. It Could Interact With Gcva And Suppress Its Activat

COG id: COG2716

COG function: function code E; Glycine cleavage system regulatory protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI87082113, Length=179, Percent_Identity=28.4916201117318, Blast_Score=62, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 20210; Mature: 20079

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKDSVVHFALSVVGKDRPGIVAGTTGILYRLGCNIEDSSSTMLGGEFAMILIISHPKPF
CCCCHHHHEEEEHHCCCCCCEEEECCEEEEEECCCCCCCCCEEECCCEEEEEEEECCCCC
TKSRLLEEFRVLGEDMGLTVSARTMTPDEAEYRAPEGEICMLSVYGSDKPGIVYRVTKEL
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCCCCCCEEEEEEECCCCCCEEEEEHHHH
AERSINITDLNTKLVGKKGEPVYVMMIEAALPEGISVDQVSAMLEEIRKELNVEISVRSI
HHCCCCEEECCEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
TPVSL
CCCCC
>Mature Secondary Structure 
TKDSVVHFALSVVGKDRPGIVAGTTGILYRLGCNIEDSSSTMLGGEFAMILIISHPKPF
CCCHHHHEEEEHHCCCCCCEEEECCEEEEEECCCCCCCCCEEECCCEEEEEEEECCCCC
TKSRLLEEFRVLGEDMGLTVSARTMTPDEAEYRAPEGEICMLSVYGSDKPGIVYRVTKEL
HHHHHHHHHHHHCCCCCCEEEEEECCCCCHHCCCCCCCEEEEEEECCCCCCEEEEEHHHH
AERSINITDLNTKLVGKKGEPVYVMMIEAALPEGISVDQVSAMLEEIRKELNVEISVRSI
HHCCCCEEECCEEEECCCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHHHCCEEEEEEEE
TPVSL
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA