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The map label for this gene is nuoG [H]

Identifier: 39998528

GI number: 39998528

Start: 3783961

End: 3785994

Strand: Reverse

Name: nuoG [H]

Synonym: GSU3439

Alternate gene names: 39998528

Gene position: 3785994-3783961 (Counterclockwise)

Preceding gene: 39998529

Following gene: 39998527

Centisome position: 99.26

GC content: 66.22

Gene sequence:

>2034_bases
ATGCCCAAACTGACCATCGATCACATACTGGTCGAAGTCCCTCCCGGCACCAGCGTGCTGGAGGCGGCCAAGACCGCGGG
AATCTGGATTCCGCACTTCTGCTATCACCCGGCCCTCGGCAGCGTGGGGGCCTGCCGGCTCTGTGCCGTGAAGCTGCTGG
ACGGACCTGTGAAGGGGATCCAGATGTCGTGCATGCTCCCGGCCCAGGACGGCATGGTGGTCTCCACCACCGACCCCGAG
GCCTTGAAGATGCGGAGCCTGGTCATCGAGTGGCTCATGACCAATCACCCCCACGACTGCCCGGTCTGCGACGAGGGGGG
GGAGTGCCTCCTTCAGGACTACACCGTGGCCGGCGGCCACGGCATCCGCCGCTTTGAGGGGAAAAAACGGACCCACGTGA
ACCAGGATCTGGGGCCGCACATTCAGCACGAGATGAACCGCTGCATCCAGTGCTACCGGTGCGTCCGCTTCTACCAGGAG
TATGCCGGCGGCAGCGACTTCGGGGTCATGGGGAGCGCCCGGCGGGTCTACTACGGCCGGTTTGAGGAGGGGGAGCTCGA
ATCCCCCTTCTCGGGAAATCTCGTCGACATCTGCCCCACCGGGGTCTTTACCGACAAGACCGCCCGGTTCCGGGCCCGTT
ACTGGGACTACGAGATGGCCCCTTCGGTCTGCCCCTGGTGTTCCCTCGGCTGCAACACCGTGCCGGCGGCCCGCTACCGG
GAACTCCTCAAGACCATGGCCCGGGAGAACCCCGCCGTGAACGGCCACTTCATCTGCGACCGGGGGCGGTTCTCCAATGC
CGCCGTGAACGACCCGGTGCGGCCGAGGGTGCCGCTGGTGGACGGGGAGGAGGTTTCATGGGCCGCGGCCATCGACGCCA
CCATGCTCCGGATTGAAGAGTTCATGGAACTCTACGGCCCCGGCCGCTTGGCCCTGGTCGGCTCACCCCGTCTCCCGCTG
GAGGGGAGTGTCCTTCTGGCACGGCTGGCCGGGCTCATCGGGACGGAGTACCTTTGTTACTTTGCCGAGCGGGACGAAGG
GGAGCGGGTAGCCGCCGCCGTTTCCCTCCTTGCCGACGGCAGGGCGGCCTCCATGGCGGACGTACGGAAGGCCGACTGCA
TTGTCATCCTCGAGTCGGACCTCCGGGACGAAGGGCCGATGATGCTTCTGGCGGTCCGGCAGGCATGGCGCAGCGGCGCA
CCGGTCTTCCTGGTGGGGACGCATGCGCCCCTTGAGCAAGCCCGAGCCGTTTCCATCGAGGCCATCGAGCTCAGCATTAT
TGAAGAGGTGCCTCTGGCGATATTCGAGAGGGCTGTGGTCATCTGCGGCACCAGGAACAATCCTCCCGCAGCCACTGAGT
TACTTGCCCATACTGATGCCAAAATCGCGTACCTCTTTCCCGGTCCCAACGCCTTTGGGGCGGGTCTTCTGGCGAAGGAG
CACGGAGCGGTTACCCTGGCCGAGGCCGTTGCCTCGGGGAGAGTGAAGGGGATCATCGCTGTAGAGGCCGACATCCCCGA
GGCGCTCCTGGCCGGCGTGCCGTTCGTGGTGGCCGCTGACTGGCTTCCGACGGAAACGGTCAGGCGTGCCCAGATCGTCA
TCCCCACCGCCGCCTGGGTGGAGACGGACGGCACCTATGTCAACTTTGAAGGGCGCGCCCAGCGGTTCCGGAAGGTCATG
GCGCCCGGACTTCCGATTCGGGGGCTCCCGGCCCGCTACCACGCCTCCCCCGACAAGCCGGCGCCGTTCCATCCGCCGCG
GGTGCACCGCAGCGCCCCCCCCGGCGGGGAACTCCGCCCCGCTTGGCGGTTCGTGGCCGAGCTGGTGGAGCGGTTCGGGG
GCGAAGCGGTGACGGGGGGGGTGCCGGACGGTGGGAGCTGCTGCGGGACCTCGACCCGGAAGGGAGAGGGGAAACGGTGC
TGTAGTGAAAAATGTTGCGCGAAACTGAACCACATCTCGATAACTGGCAAGAGTGGTTTACTCAACAGGTACTTCCAGAG
GACCGTGCACTACGCGGCGGCTCCTGGAGTCTGA

Upstream 100 bases:

>100_bases
CATCGGCATCATCATCACCCTTGGCTGGGGAAGTCTCGTCATGGCGCTCCAGTACGACAAGGGGGAACAACCACGGGTGA
TTATCCTGTAACCTGAAACC

Downstream 100 bases:

>100_bases
CTTACCAAACAGAAAAAGGAGCACCATGAGCAGTTTACCCGCATGCCCACAATGCAGTTCGGAATACACCTATGAAGACG
GGACCATGTACGTCTGCCCG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 677; Mature: 676

Protein sequence:

>677_residues
MPKLTIDHILVEVPPGTSVLEAAKTAGIWIPHFCYHPALGSVGACRLCAVKLLDGPVKGIQMSCMLPAQDGMVVSTTDPE
ALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGHGIRRFEGKKRTHVNQDLGPHIQHEMNRCIQCYRCVRFYQE
YAGGSDFGVMGSARRVYYGRFEEGELESPFSGNLVDICPTGVFTDKTARFRARYWDYEMAPSVCPWCSLGCNTVPAARYR
ELLKTMARENPAVNGHFICDRGRFSNAAVNDPVRPRVPLVDGEEVSWAAAIDATMLRIEEFMELYGPGRLALVGSPRLPL
EGSVLLARLAGLIGTEYLCYFAERDEGERVAAAVSLLADGRAASMADVRKADCIVILESDLRDEGPMMLLAVRQAWRSGA
PVFLVGTHAPLEQARAVSIEAIELSIIEEVPLAIFERAVVICGTRNNPPAATELLAHTDAKIAYLFPGPNAFGAGLLAKE
HGAVTLAEAVASGRVKGIIAVEADIPEALLAGVPFVVAADWLPTETVRRAQIVIPTAAWVETDGTYVNFEGRAQRFRKVM
APGLPIRGLPARYHASPDKPAPFHPPRVHRSAPPGGELRPAWRFVAELVERFGGEAVTGGVPDGGSCCGTSTRKGEGKRC
CSEKCCAKLNHISITGKSGLLNRYFQRTVHYAAAPGV

Sequences:

>Translated_677_residues
MPKLTIDHILVEVPPGTSVLEAAKTAGIWIPHFCYHPALGSVGACRLCAVKLLDGPVKGIQMSCMLPAQDGMVVSTTDPE
ALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGHGIRRFEGKKRTHVNQDLGPHIQHEMNRCIQCYRCVRFYQE
YAGGSDFGVMGSARRVYYGRFEEGELESPFSGNLVDICPTGVFTDKTARFRARYWDYEMAPSVCPWCSLGCNTVPAARYR
ELLKTMARENPAVNGHFICDRGRFSNAAVNDPVRPRVPLVDGEEVSWAAAIDATMLRIEEFMELYGPGRLALVGSPRLPL
EGSVLLARLAGLIGTEYLCYFAERDEGERVAAAVSLLADGRAASMADVRKADCIVILESDLRDEGPMMLLAVRQAWRSGA
PVFLVGTHAPLEQARAVSIEAIELSIIEEVPLAIFERAVVICGTRNNPPAATELLAHTDAKIAYLFPGPNAFGAGLLAKE
HGAVTLAEAVASGRVKGIIAVEADIPEALLAGVPFVVAADWLPTETVRRAQIVIPTAAWVETDGTYVNFEGRAQRFRKVM
APGLPIRGLPARYHASPDKPAPFHPPRVHRSAPPGGELRPAWRFVAELVERFGGEAVTGGVPDGGSCCGTSTRKGEGKRC
CSEKCCAKLNHISITGKSGLLNRYFQRTVHYAAAPGV
>Mature_676_residues
PKLTIDHILVEVPPGTSVLEAAKTAGIWIPHFCYHPALGSVGACRLCAVKLLDGPVKGIQMSCMLPAQDGMVVSTTDPEA
LKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGHGIRRFEGKKRTHVNQDLGPHIQHEMNRCIQCYRCVRFYQEY
AGGSDFGVMGSARRVYYGRFEEGELESPFSGNLVDICPTGVFTDKTARFRARYWDYEMAPSVCPWCSLGCNTVPAARYRE
LLKTMARENPAVNGHFICDRGRFSNAAVNDPVRPRVPLVDGEEVSWAAAIDATMLRIEEFMELYGPGRLALVGSPRLPLE
GSVLLARLAGLIGTEYLCYFAERDEGERVAAAVSLLADGRAASMADVRKADCIVILESDLRDEGPMMLLAVRQAWRSGAP
VFLVGTHAPLEQARAVSIEAIELSIIEEVPLAIFERAVVICGTRNNPPAATELLAHTDAKIAYLFPGPNAFGAGLLAKEH
GAVTLAEAVASGRVKGIIAVEADIPEALLAGVPFVVAADWLPTETVRRAQIVIPTAAWVETDGTYVNFEGRAQRFRKVMA
PGLPIRGLPARYHASPDKPAPFHPPRVHRSAPPGGELRPAWRFVAELVERFGGEAVTGGVPDGGSCCGTSTRKGEGKRCC
SEKCCAKLNHISITGKSGLLNRYFQRTVHYAAAPGV

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=603, Percent_Identity=28.6898839137645, Blast_Score=232, Evalue=8e-61,
Organism=Escherichia coli, GI145693161, Length=650, Percent_Identity=38.1538461538462, Blast_Score=395, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI17565758, Length=588, Percent_Identity=30.1020408163265, Blast_Score=221, Evalue=1e-57,
Organism=Caenorhabditis elegans, GI32566231, Length=580, Percent_Identity=30.1724137931034, Blast_Score=220, Evalue=2e-57,
Organism=Caenorhabditis elegans, GI193209088, Length=251, Percent_Identity=39.4422310756972, Blast_Score=187, Evalue=1e-47,
Organism=Drosophila melanogaster, GI24640559, Length=577, Percent_Identity=30.155979202773, Blast_Score=224, Evalue=1e-58,
Organism=Drosophila melanogaster, GI24640557, Length=577, Percent_Identity=30.155979202773, Blast_Score=224, Evalue=1e-58,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR006963
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574 [H]

Pfam domain/function: PF00111 Fer2; PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 73452; Mature: 73321

Theoretical pI: Translated: 6.96; Mature: 6.96

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKLTIDHILVEVPPGTSVLEAAKTAGIWIPHFCYHPALGSVGACRLCAVKLLDGPVKGI
CCCEEEEEEEEECCCCCHHHHHHHHCCEECCHHHHCCCCCCCCHHHHHHHHHHCCCCCCE
QMSCMLPAQDGMVVSTTDPEALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGH
EEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC
GIRRFEGKKRTHVNQDLGPHIQHEMNRCIQCYRCVRFYQEYAGGSDFGVMGSARRVYYGR
CEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC
FEEGELESPFSGNLVDICPTGVFTDKTARFRARYWDYEMAPSVCPWCSLGCNTVPAARYR
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHH
ELLKTMARENPAVNGHFICDRGRFSNAAVNDPVRPRVPLVDGEEVSWAAAIDATMLRIEE
HHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FMELYGPGRLALVGSPRLPLEGSVLLARLAGLIGTEYLCYFAERDEGERVAAAVSLLADG
HHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCC
RAASMADVRKADCIVILESDLRDEGPMMLLAVRQAWRSGAPVFLVGTHAPLEQARAVSIE
CHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCHHHHHEEEEE
AIELSIIEEVPLAIFERAVVICGTRNNPPAATELLAHTDAKIAYLFPGPNAFGAGLLAKE
EEEEEHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCEECC
HGAVTLAEAVASGRVKGIIAVEADIPEALLAGVPFVVAADWLPTETVRRAQIVIPTAAWV
CCCEEHHHHHHCCCEEEEEEEECCCCHHHHHCCCCEEEECCCCHHHHCCEEEEEEEHHEE
ETDGTYVNFEGRAQRFRKVMAPGLPIRGLPARYHASPDKPAPFHPPRVHRSAPPGGELRP
ECCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AWRFVAELVERFGGEAVTGGVPDGGSCCGTSTRKGEGKRCCSEKCCAKLNHISITGKSGL
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCHH
LNRYFQRTVHYAAAPGV
HHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PKLTIDHILVEVPPGTSVLEAAKTAGIWIPHFCYHPALGSVGACRLCAVKLLDGPVKGI
CCEEEEEEEEECCCCCHHHHHHHHCCEECCHHHHCCCCCCCCHHHHHHHHHHCCCCCCE
QMSCMLPAQDGMVVSTTDPEALKMRSLVIEWLMTNHPHDCPVCDEGGECLLQDYTVAGGH
EEEEEEECCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEEEEEECCC
GIRRFEGKKRTHVNQDLGPHIQHEMNRCIQCYRCVRFYQEYAGGSDFGVMGSARRVYYGR
CEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEC
FEEGELESPFSGNLVDICPTGVFTDKTARFRARYWDYEMAPSVCPWCSLGCNTVPAARYR
CCCCCCCCCCCCCEEEECCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHCCCCCCCHHHHH
ELLKTMARENPAVNGHFICDRGRFSNAAVNDPVRPRVPLVDGEEVSWAAAIDATMLRIEE
HHHHHHHHCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHH
FMELYGPGRLALVGSPRLPLEGSVLLARLAGLIGTEYLCYFAERDEGERVAAAVSLLADG
HHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHCC
RAASMADVRKADCIVILESDLRDEGPMMLLAVRQAWRSGAPVFLVGTHAPLEQARAVSIE
CHHHHHHHCCCCEEEEEECCCCCCCCEEHHHHHHHHHCCCCEEEEECCCCHHHHHEEEEE
AIELSIIEEVPLAIFERAVVICGTRNNPPAATELLAHTDAKIAYLFPGPNAFGAGLLAKE
EEEEEHHHHHHHHHHCCEEEEEECCCCCCHHHHHHHCCCCEEEEEECCCCCCCCCCEECC
HGAVTLAEAVASGRVKGIIAVEADIPEALLAGVPFVVAADWLPTETVRRAQIVIPTAAWV
CCCEEHHHHHHCCCEEEEEEEECCCCHHHHHCCCCEEEECCCCHHHHCCEEEEEEEHHEE
ETDGTYVNFEGRAQRFRKVMAPGLPIRGLPARYHASPDKPAPFHPPRVHRSAPPGGELRP
ECCCCEEEECHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCH
AWRFVAELVERFGGEAVTGGVPDGGSCCGTSTRKGEGKRCCSEKCCAKLNHISITGKSGL
HHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCEEEEECCCHH
LNRYFQRTVHYAAAPGV
HHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12118882 [H]