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The map label for this gene is groES [H]

Identifier: 39998428

GI number: 39998428

Start: 3664919

End: 3665206

Strand: Direct

Name: groES [H]

Synonym: GSU3339

Alternate gene names: 39998428

Gene position: 3664919-3665206 (Clockwise)

Preceding gene: 39998425

Following gene: 39998429

Centisome position: 96.09

GC content: 57.99

Gene sequence:

>288_bases
ATGAATCTCAGACCGTTGCAAGACCGTATCCTCGTGAAAAGAATCGAGGAGGAGACCAAGACCGCCGGCGGCATCTTCAT
CCCCGACACAGCCAAGGAGAAGCCCCAGCGCGGCGAGATCGTGGCCGTCGGTAACGGCAAGAAGACCGAGGACGGCAAGG
TGATCCCCGTTGATCTCAAGGTAGGTGACAAGGTTCTGTTCGGCAAGTATGCCGGCACCGACATCAAGATCGAGGGGCAG
GAGTTCCTCATCATGCGCGAGGACGACATCCTGGGCGTGATCGAGTAA

Upstream 100 bases:

>100_bases
GTGACTATAGTTACCACGTGTTAGCACTCAGTCGTATCGAGTGCTAATTTTTTTCGATGAAAACTCTCGAGCATATCATG
GAAGAAAGGAGAAGAAGCAG

Downstream 100 bases:

>100_bases
CCGACACCACGCCGGACAGCACAGCACTACCCGAGTGAACCAATCCAAGGAGGATAGACAGATATGGCAGCCAGAATCAT
CAAGTTCGACCAGGAAGGGC

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10 [H]

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNLRPLQDRILVKRIEEETKTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPVDLKVGDKVLFGKYAGTDIKIEGQ
EFLIMREDDILGVIE

Sequences:

>Translated_95_residues
MNLRPLQDRILVKRIEEETKTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPVDLKVGDKVLFGKYAGTDIKIEGQ
EFLIMREDDILGVIE
>Mature_95_residues
MNLRPLQDRILVKRIEEETKTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPVDLKVGDKVLFGKYAGTDIKIEGQ
EFLIMREDDILGVIE

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter [H]

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family [H]

Homologues:

Organism=Homo sapiens, GI4504523, Length=88, Percent_Identity=44.3181818181818, Blast_Score=69, Evalue=1e-12,
Organism=Homo sapiens, GI169210012, Length=88, Percent_Identity=42.0454545454545, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=53.125, Blast_Score=100, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=40.4255319148936, Blast_Score=84, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=42.3913043478261, Blast_Score=69, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356029, Length=94, Percent_Identity=42.5531914893617, Blast_Score=72, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21358317, Length=93, Percent_Identity=41.9354838709677, Blast_Score=70, Evalue=2e-13,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032 [H]

Pfam domain/function: PF00166 Cpn10 [H]

EC number: NA

Molecular weight: Translated: 10536; Mature: 10536

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRPLQDRILVKRIEEETKTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPVDLK
CCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDKVLFGKYAGTDIKIEGQEFLIMREDDILGVIE
CCCEEEEEEECCCEEEECCCEEEEEECCCEEEEEC
>Mature Secondary Structure
MNLRPLQDRILVKRIEEETKTAGGIFIPDTAKEKPQRGEIVAVGNGKKTEDGKVIPVDLK
CCCCCCHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCEEEECCCCCCCCCCEEEEEEC
VGDKVLFGKYAGTDIKIEGQEFLIMREDDILGVIE
CCCEEEEEEECCCEEEECCCEEEEEECCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA