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The map label for this gene is yccK [H]

Identifier: 39998216

GI number: 39998216

Start: 3426711

End: 3427715

Strand: Reverse

Name: yccK [H]

Synonym: GSU3126

Alternate gene names: 39998216

Gene position: 3427715-3426711 (Counterclockwise)

Preceding gene: 39998220

Following gene: 39998215

Centisome position: 89.87

GC content: 63.58

Gene sequence:

>1005_bases
ATGCACAAACGACTATTGGGGAAAAGCGGTCTGGAAGTCTCGGCGCTCGGGCTCGGTTGCATGGGGATGAGCTTTTCGTA
TGGACCTCCAAAAGACCGGGAGGAGATGATCGCGCTGCTTCGGACCGCCGTGGAGCGGGGCATTACCTTTTTCGACACGG
CGGAGGTCTATGGTCCGTTCATCAACGAGGAACTGGTCGGTGAGGCGCTCGCGCCGTTGCGCGAACGGGTGGTGATCGCC
ACCAAGTTCGGGTTCGATACCAGTGTCGATCCGCGGGCGATGAAGGGGCAGGGGCCGGTATTGAACAGCCGGCCGGAGCA
CATCAGGGCGGTCGCCGAAGCGTCGCTCAGGCGGCTGCGGACGGACGTCATCGATCTCTTCTACCAGCACCGGGTCGACC
CAGCGGTGCCGATCGAAGAGGTGGCGGGGGCGGTAAAGGAACTGATCCGGGAAGGGAAGGTCAAGCACTTCGGCCTGTCG
GAAGCGGGCATCGAGACGGTCCGCCGTGCCCATGCCGTGCAGCCGGTGGCCTGCGTGCAGAACGAGTACTCGCTCTGGTT
CCGGCGCCCGGAAGAGGGATTGCTGCAGGCTCTGGAAGAACTCGGCATCGGCCTCGTTGCCTACAGCCCGCTCGGCAAGG
GGTTCCTTACCGGGAAGATCGGCGGTGACTCCACGTTCGACAGCACCGATTTCCGCAGCACCCTGCCCCGTTTCGCACCC
GAGGCGCTGAAGGCGAACCAAGCCCTGGTCGATCTGCTCGGCAGGATTGCAGAACAAAAGAATGCGACCCCGGCCCAGAT
CGCCCTGGCCTGGCTGCTGTCCAGGAAGCCGTGGATCGTGCCGATTCCGGGCACCACGAAGCTGGATCGCCTGAACGAGA
ACATCGGCGCACTCGCCGTCGAACTGACCGCAGCGGATCTGTCCGCGATCGAAACGGCTGCCGCGCAGATAGCCATCCAG
GGTAACCGGTACCCGGAAAAGCTGGAGCAGTTGACCGGGAGATAG

Upstream 100 bases:

>100_bases
CGATCAGGCAAGAATCAGGCAGGATCGGTCTACCGTCCCTCGCCTCGCCTGGGGTACGTTTTAACCACCCGAAAGGGAAC
GCGGGTGAAAGGAGAAAACG

Downstream 100 bases:

>100_bases
TCATGTTGCCCCTCATCGTCCCTCTCCCCAACGGGCGAGGCGAGAAGACCCAGAGGGCCGGGGTGAGGGGCAAGGCAGTG
TAAAAACAAACCGCCAAGGA

Product: aldo/keto reductase family oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MHKRLLGKSGLEVSALGLGCMGMSFSYGPPKDREEMIALLRTAVERGITFFDTAEVYGPFINEELVGEALAPLRERVVIA
TKFGFDTSVDPRAMKGQGPVLNSRPEHIRAVAEASLRRLRTDVIDLFYQHRVDPAVPIEEVAGAVKELIREGKVKHFGLS
EAGIETVRRAHAVQPVACVQNEYSLWFRRPEEGLLQALEELGIGLVAYSPLGKGFLTGKIGGDSTFDSTDFRSTLPRFAP
EALKANQALVDLLGRIAEQKNATPAQIALAWLLSRKPWIVPIPGTTKLDRLNENIGALAVELTAADLSAIETAAAQIAIQ
GNRYPEKLEQLTGR

Sequences:

>Translated_334_residues
MHKRLLGKSGLEVSALGLGCMGMSFSYGPPKDREEMIALLRTAVERGITFFDTAEVYGPFINEELVGEALAPLRERVVIA
TKFGFDTSVDPRAMKGQGPVLNSRPEHIRAVAEASLRRLRTDVIDLFYQHRVDPAVPIEEVAGAVKELIREGKVKHFGLS
EAGIETVRRAHAVQPVACVQNEYSLWFRRPEEGLLQALEELGIGLVAYSPLGKGFLTGKIGGDSTFDSTDFRSTLPRFAP
EALKANQALVDLLGRIAEQKNATPAQIALAWLLSRKPWIVPIPGTTKLDRLNENIGALAVELTAADLSAIETAAAQIAIQ
GNRYPEKLEQLTGR
>Mature_334_residues
MHKRLLGKSGLEVSALGLGCMGMSFSYGPPKDREEMIALLRTAVERGITFFDTAEVYGPFINEELVGEALAPLRERVVIA
TKFGFDTSVDPRAMKGQGPVLNSRPEHIRAVAEASLRRLRTDVIDLFYQHRVDPAVPIEEVAGAVKELIREGKVKHFGLS
EAGIETVRRAHAVQPVACVQNEYSLWFRRPEEGLLQALEELGIGLVAYSPLGKGFLTGKIGGDSTFDSTDFRSTLPRFAP
EALKANQALVDLLGRIAEQKNATPAQIALAWLLSRKPWIVPIPGTTKLDRLNENIGALAVELTAADLSAIETAAAQIAIQ
GNRYPEKLEQLTGR

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=340, Percent_Identity=30.2941176470588, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI4504825, Length=337, Percent_Identity=30.2670623145401, Blast_Score=118, Evalue=9e-27,
Organism=Homo sapiens, GI27436964, Length=315, Percent_Identity=31.1111111111111, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI27436971, Length=315, Percent_Identity=31.7460317460317, Blast_Score=115, Evalue=7e-26,
Organism=Homo sapiens, GI27436966, Length=315, Percent_Identity=31.1111111111111, Blast_Score=115, Evalue=8e-26,
Organism=Homo sapiens, GI27436962, Length=315, Percent_Identity=31.1111111111111, Blast_Score=114, Evalue=1e-25,
Organism=Homo sapiens, GI223718702, Length=231, Percent_Identity=32.034632034632, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI41327764, Length=204, Percent_Identity=31.8627450980392, Blast_Score=76, Evalue=4e-14,
Organism=Homo sapiens, GI41152114, Length=208, Percent_Identity=31.25, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI1789375, Length=334, Percent_Identity=32.6347305389222, Blast_Score=141, Evalue=8e-35,
Organism=Escherichia coli, GI87081735, Length=329, Percent_Identity=31.6109422492401, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1787674, Length=309, Percent_Identity=31.7152103559871, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1788070, Length=341, Percent_Identity=29.9120234604106, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789199, Length=347, Percent_Identity=31.4121037463977, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI1788081, Length=317, Percent_Identity=29.0220820189274, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI48994888, Length=287, Percent_Identity=30.6620209059233, Blast_Score=98, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17550248, Length=314, Percent_Identity=25.796178343949, Blast_Score=71, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17566692, Length=321, Percent_Identity=25.2336448598131, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325384, Length=350, Percent_Identity=29.4285714285714, Blast_Score=126, Evalue=5e-30,
Organism=Saccharomyces cerevisiae, GI6325169, Length=338, Percent_Identity=28.1065088757396, Blast_Score=117, Evalue=3e-27,
Organism=Saccharomyces cerevisiae, GI6323998, Length=326, Percent_Identity=28.8343558282209, Blast_Score=105, Evalue=7e-24,
Organism=Saccharomyces cerevisiae, GI6319958, Length=293, Percent_Identity=26.6211604095563, Blast_Score=96, Evalue=9e-21,
Organism=Saccharomyces cerevisiae, GI6319951, Length=326, Percent_Identity=27.3006134969325, Blast_Score=96, Evalue=1e-20,
Organism=Saccharomyces cerevisiae, GI6322615, Length=264, Percent_Identity=27.2727272727273, Blast_Score=87, Evalue=5e-18,
Organism=Drosophila melanogaster, GI24640980, Length=327, Percent_Identity=27.5229357798165, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI45549126, Length=327, Percent_Identity=27.5229357798165, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24646159, Length=230, Percent_Identity=29.1304347826087, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI24646155, Length=178, Percent_Identity=32.5842696629214, Blast_Score=72, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36476; Mature: 36476

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKRLLGKSGLEVSALGLGCMGMSFSYGPPKDREEMIALLRTAVERGITFFDTAEVYGPF
CCCCCCCCCCCEEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHCCC
INEELVGEALAPLRERVVIATKFGFDTSVDPRAMKGQGPVLNSRPEHIRAVAEASLRRLR
CCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TDVIDLFYQHRVDPAVPIEEVAGAVKELIREGKVKHFGLSEAGIETVRRAHAVQPVACVQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHC
NEYSLWFRRPEEGLLQALEELGIGLVAYSPLGKGFLTGKIGGDSTFDSTDFRSTLPRFAP
CCHHHEEECCHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCH
EALKANQALVDLLGRIAEQKNATPAQIALAWLLSRKPWIVPIPGTTKLDRLNENIGALAV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCEEE
ELTAADLSAIETAAAQIAIQGNRYPEKLEQLTGR
EEHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCC
>Mature Secondary Structure
MHKRLLGKSGLEVSALGLGCMGMSFSYGPPKDREEMIALLRTAVERGITFFDTAEVYGPF
CCCCCCCCCCCEEEEECHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHCCC
INEELVGEALAPLRERVVIATKFGFDTSVDPRAMKGQGPVLNSRPEHIRAVAEASLRRLR
CCHHHHHHHHHHHHHCEEEEEECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
TDVIDLFYQHRVDPAVPIEEVAGAVKELIREGKVKHFGLSEAGIETVRRAHAVQPVACVQ
HHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCHHHHHC
NEYSLWFRRPEEGLLQALEELGIGLVAYSPLGKGFLTGKIGGDSTFDSTDFRSTLPRFAP
CCHHHEEECCHHHHHHHHHHCCCCEEEECCCCCCEEEECCCCCCCCCCCHHHHHHHHHCH
EALKANQALVDLLGRIAEQKNATPAQIALAWLLSRKPWIVPIPGTTKLDRLNENIGALAV
HHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCCCHHHHHHCCCCCEEE
ELTAADLSAIETAAAQIAIQGNRYPEKLEQLTGR
EEHHHHHHHHHHHHHHEEECCCCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9274031; 9384377; 9106203 [H]