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The map label for this gene is murA [H]

Identifier: 39998192

GI number: 39998192

Start: 3405581

End: 3406834

Strand: Reverse

Name: murA [H]

Synonym: GSU3102

Alternate gene names: 39998192

Gene position: 3406834-3405581 (Counterclockwise)

Preceding gene: 39998193

Following gene: 39998191

Centisome position: 89.32

GC content: 61.56

Gene sequence:

>1254_bases
TTGGACAAGCTGATCATCAAAGGTGGAAAGAAACTGATCGGAGAGGTCTCGGTCAGTGGCTCCAAGAACGCGGCTCTCCC
CATTTTCGTTTCCACCATCCTCGCCCCCGGCCTCAACGAGATCCGTAACGTTCCTTTCCTGCGCGATATCAACACAACCA
TCAAGGTCCTGGAATCCCTGGGTGCCGTGGTGGAAGGAAACGGCAACATCGTCAGGATCGATACGACCCACGTGAACAAC
GTGGAGGCCACCTATGATCTCGTGAAGACCATGCGGGCGTCGGTCCTGGTATTGGGTCCGCTGCTGGCCCGCCACGGCCG
GGCACGGGTTTCCCTTCCCGGCGGTTGCGCCATCGGTGCCCGTCCCATCAACCTCCACCTCAAGGGGCTTGCCGCACTGG
GCGCCGACATCCGGCTGGAGCACGGCTACGTGGAGGCCAAGGCGAAAAAGCTCAAGGGTGCCCGCATCAATTTCGACATT
TCCACCGTTGGCGGCACTGAGCAGCTGATGATGGCGGCGGCCCTGGCCAAAGGGGAAACGGTTCTGGAGAACGCCGCCCG
GGAGCCCGAGATCATCGATCTGGCCGAGATACTGATCAAGATGGGGGCGAAGATTGACGGTGCCGGCACCGACACCATCC
GGATCACCGGGGTTAAGGAGTTGGCGCCGGTTGCCCACGACGTCATGCCCGACCGGATCGAAGCGGGCACGTTCATGGTG
GCGGCGGCCATCACCGGCGGCGACATCAAGATCCGCAACATGAAGCTGGAGCACCTGGATGCGCTCGTGTTCAAGCTTCA
GGATGCCGGCGTGGAGATCACCAATCGCGACAACGTGGTGCGGGTGAAGGGCCCCCGCCGTCCCAAGGCCGTGAACATCA
AGACGCGCCCCTATCCGGGCTTTCCCACCGATATGCAGGCCCAGTTCATGGCCCTCATGTGCGTGGCCGACGGAGCGAGT
GTCATCAGCGAGAATATTTTCGAGAACCGTTTCATGCACGTCTCGGAGCTGTTGCGCTTCGGTGCCGACATCACGGTCGA
GGGGAGCACCGCCACCGTGAAAGGGGTGAAGAAACTGTCGGGCGCGCCGGTCATGGCCACGGATCTCCGGGCCTCGGCGT
CGCTCATTCTCGCCGGCCTGGCAGCCGACAATACTACCGAGATCTCACGTATCTACCACCTGGACCGGGGATACGAGTCC
ATCGAAAAGAAGCTGGCCGGCCTCGGTGCCGATATCCAACGTGTAAAGGAGTGA

Upstream 100 bases:

>100_bases
ACCCCAACGGCATAGACCGGGTGGTCGGCGGAAGGATCGGATAGGCCGGGTTTCACGCGAGACTTGGCCCCGAACACACT
ATCACGACAGAGGCATTCCA

Downstream 100 bases:

>100_bases
CCCGACGGCAGGCGCGGGTGCCGATGCAGGCCCCCGGCTCCTGGTCGCCGGTCCCTGACATGTCATGACCGACTACATTA
CCATCGCCATCCCCAAGGGG

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 417; Mature: 417

Protein sequence:

>417_residues
MDKLIIKGGKKLIGEVSVSGSKNAALPIFVSTILAPGLNEIRNVPFLRDINTTIKVLESLGAVVEGNGNIVRIDTTHVNN
VEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAKKLKGARINFDI
STVGGTEQLMMAAALAKGETVLENAAREPEIIDLAEILIKMGAKIDGAGTDTIRITGVKELAPVAHDVMPDRIEAGTFMV
AAAITGGDIKIRNMKLEHLDALVFKLQDAGVEITNRDNVVRVKGPRRPKAVNIKTRPYPGFPTDMQAQFMALMCVADGAS
VISENIFENRFMHVSELLRFGADITVEGSTATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEISRIYHLDRGYES
IEKKLAGLGADIQRVKE

Sequences:

>Translated_417_residues
MDKLIIKGGKKLIGEVSVSGSKNAALPIFVSTILAPGLNEIRNVPFLRDINTTIKVLESLGAVVEGNGNIVRIDTTHVNN
VEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAKKLKGARINFDI
STVGGTEQLMMAAALAKGETVLENAAREPEIIDLAEILIKMGAKIDGAGTDTIRITGVKELAPVAHDVMPDRIEAGTFMV
AAAITGGDIKIRNMKLEHLDALVFKLQDAGVEITNRDNVVRVKGPRRPKAVNIKTRPYPGFPTDMQAQFMALMCVADGAS
VISENIFENRFMHVSELLRFGADITVEGSTATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEISRIYHLDRGYES
IEKKLAGLGADIQRVKE
>Mature_417_residues
MDKLIIKGGKKLIGEVSVSGSKNAALPIFVSTILAPGLNEIRNVPFLRDINTTIKVLESLGAVVEGNGNIVRIDTTHVNN
VEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGARPINLHLKGLAALGADIRLEHGYVEAKAKKLKGARINFDI
STVGGTEQLMMAAALAKGETVLENAAREPEIIDLAEILIKMGAKIDGAGTDTIRITGVKELAPVAHDVMPDRIEAGTFMV
AAAITGGDIKIRNMKLEHLDALVFKLQDAGVEITNRDNVVRVKGPRRPKAVNIKTRPYPGFPTDMQAQFMALMCVADGAS
VISENIFENRFMHVSELLRFGADITVEGSTATVKGVKKLSGAPVMATDLRASASLILAGLAADNTTEISRIYHLDRGYES
IEKKLAGLGADIQRVKE

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=57.177033492823, Blast_Score=455, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44518; Mature: 44518

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDKLIIKGGKKLIGEVSVSGSKNAALPIFVSTILAPGLNEIRNVPFLRDINTTIKVLESL
CCCEEEECCCEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCEEHHHHHHHHHHHC
GAVVEGNGNIVRIDTTHVNNVEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGA
CCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECC
RPINLHLKGLAALGADIRLEHGYVEAKAKKLKGARINFDISTVGGTEQLMMAAALAKGET
EEEEEEEEEHHHCCCCEEEECCCHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHCCHH
VLENAAREPEIIDLAEILIKMGAKIDGAGTDTIRITGVKELAPVAHDVMPDRIEAGTFMV
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHCCCCHHCCCEEEE
AAAITGGDIKIRNMKLEHLDALVFKLQDAGVEITNRDNVVRVKGPRRPKAVNIKTRPYPG
EEEEECCCEEEEEEEHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCCEEEEECCCCCC
FPTDMQAQFMALMCVADGASVISENIFENRFMHVSELLRFGADITVEGSTATVKGVKKLS
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHC
GAPVMATDLRASASLILAGLAADNTTEISRIYHLDRGYESIEKKLAGLGADIQRVKE
CCCEEEHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCC
>Mature Secondary Structure
MDKLIIKGGKKLIGEVSVSGSKNAALPIFVSTILAPGLNEIRNVPFLRDINTTIKVLESL
CCCEEEECCCEEEEEEEECCCCCCCHHHHHHHHHCCCHHHHHCCCCEEHHHHHHHHHHHC
GAVVEGNGNIVRIDTTHVNNVEATYDLVKTMRASVLVLGPLLARHGRARVSLPGGCAIGA
CCEEECCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEECC
RPINLHLKGLAALGADIRLEHGYVEAKAKKLKGARINFDISTVGGTEQLMMAAALAKGET
EEEEEEEEEHHHCCCCEEEECCCHHHHHHHCCCCEEEEEEEECCCHHHHHHHHHHHCCHH
VLENAAREPEIIDLAEILIKMGAKIDGAGTDTIRITGVKELAPVAHDVMPDRIEAGTFMV
HHHHCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEECHHHHHHHHHHCCCCHHCCCEEEE
AAAITGGDIKIRNMKLEHLDALVFKLQDAGVEITNRDNVVRVKGPRRPKAVNIKTRPYPG
EEEEECCCEEEEEEEHHHHHHHHHHHHHCCEEEECCCCEEEECCCCCCCEEEEECCCCCC
FPTDMQAQFMALMCVADGASVISENIFENRFMHVSELLRFGADITVEGSTATVKGVKKLS
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCHHHHHHHHHC
GAPVMATDLRASASLILAGLAADNTTEISRIYHLDRGYESIEKKLAGLGADIQRVKE
CCCEEEHHHHCCCEEEEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA