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The map label for this gene is pheA [H]

Identifier: 39997702

GI number: 39997702

Start: 2875863

End: 2876939

Strand: Reverse

Name: pheA [H]

Synonym: GSU2608

Alternate gene names: 39997702

Gene position: 2876939-2875863 (Counterclockwise)

Preceding gene: 39997703

Following gene: 39997701

Centisome position: 75.43

GC content: 63.23

Gene sequence:

>1077_bases
TTGAGCGCGACACGCAATCTCGACGCACTGCGGCGCGAGATCGACGCCATTGACGATGCCATCCTCGATCTGCTCAACCG
CCGTGCCGGACTGGTCATGGAGGTGGGACAGGTCAAGACCGTGGAGAAGCGCGATTTTCACGTGCCGAACCGTGAACGGG
AGATTTACGAGCGGCTGCTCGCCCACAACACCGGCCCCTTTCCGGCCGAGGCGGTCAAGAGCGTGTTCCGGGAGATCATC
TCCGCTTCACTCGCCCTTGAGGCGCCCATGAAGGTGGCGTTCCTGGGGCCCCGGGCGACCTTCACCCACCTGGCCACCAT
GCAGCACTTCGGCCTGGCCGCGGAGCTGGTCGCCCAGAAATCGATCCCTGCCGTGTTCGAGGAAGTGGAGAAGGGCCGCG
CTCTCTACGGTGTCGTGCCGGTCGAGAACTCCACCGAGGGGATGGTTTCCCACACCCTCGACATGTTCATGGAGAGCGAC
CTCAAGATCAACGCCGAGGTTCTGCTGGAAGTGTCCCACGACCTCCTCTCCCGCACCGGCCGGCTGGACGACGTGAAGAA
GGTCTATTCGCATCCCCAGGCCCTTGCCCAGTGCCGCAAGTGGCTCGACGACAACCTGCCGGGTGTGCCGGTGGTGGACG
TGGCGTCCACTGCCCTGGCCGCCCAGATCGTGAGCGAGGATTACGCGGCCGCGGCCATTGCCAGCGAGTTCGCCGCGGCC
CAGTACGACCTGAAGGTAGTGCGCACGAGAATTGAGGACCAGGTCAACAACTTCACCCGCTTCCTCGTCATCGGCCGGAA
GATGGCGGATCGGAGCGGCGACGACAAGACCTCGCTCATGTTTTCCGTCAAGGACGAGCCGGGCATCCTCTACCGGATGC
TGGAGCCCTTCGCCTCCCGCGGCGTCAACCTGTCCAAGATCGAATCCCGCCCCCTCAAGAAGAAGGCGTGGGAATACATT
TTTTACCTGGACCTGGCCGGCCACATCACCGATCCGGTGGTTGCCGAGGCGGTTCAGGACCTGGGACGCTACTGCCAGTT
CGTGAAAATTCTCGGCTCCTATCCCAGGGCGAAATGA

Upstream 100 bases:

>100_bases
TGGTGTAAACCATAAAATGTTTGCATTTTAGCCCCCTTTGCTATACAGTACCTCCCTCCGCGGAACTGCCGCACCATATT
TCTCCCCCCAGGTGACCCCC

Downstream 100 bases:

>100_bases
GCGGTTCCGTCCCCTTTATCCGGCGACTGGCCGTCATCGGCGTCGGCCTCATCGGCGGTTCCCTGGCGCGGGCCCTGCGG
ACGGCCGGTGCCGTGGGTGA

Product: chorismate mutase/prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 358; Mature: 357

Protein sequence:

>358_residues
MSATRNLDALRREIDAIDDAILDLLNRRAGLVMEVGQVKTVEKRDFHVPNREREIYERLLAHNTGPFPAEAVKSVFREII
SASLALEAPMKVAFLGPRATFTHLATMQHFGLAAELVAQKSIPAVFEEVEKGRALYGVVPVENSTEGMVSHTLDMFMESD
LKINAEVLLEVSHDLLSRTGRLDDVKKVYSHPQALAQCRKWLDDNLPGVPVVDVASTALAAQIVSEDYAAAAIASEFAAA
QYDLKVVRTRIEDQVNNFTRFLVIGRKMADRSGDDKTSLMFSVKDEPGILYRMLEPFASRGVNLSKIESRPLKKKAWEYI
FYLDLAGHITDPVVAEAVQDLGRYCQFVKILGSYPRAK

Sequences:

>Translated_358_residues
MSATRNLDALRREIDAIDDAILDLLNRRAGLVMEVGQVKTVEKRDFHVPNREREIYERLLAHNTGPFPAEAVKSVFREII
SASLALEAPMKVAFLGPRATFTHLATMQHFGLAAELVAQKSIPAVFEEVEKGRALYGVVPVENSTEGMVSHTLDMFMESD
LKINAEVLLEVSHDLLSRTGRLDDVKKVYSHPQALAQCRKWLDDNLPGVPVVDVASTALAAQIVSEDYAAAAIASEFAAA
QYDLKVVRTRIEDQVNNFTRFLVIGRKMADRSGDDKTSLMFSVKDEPGILYRMLEPFASRGVNLSKIESRPLKKKAWEYI
FYLDLAGHITDPVVAEAVQDLGRYCQFVKILGSYPRAK
>Mature_357_residues
SATRNLDALRREIDAIDDAILDLLNRRAGLVMEVGQVKTVEKRDFHVPNREREIYERLLAHNTGPFPAEAVKSVFREIIS
ASLALEAPMKVAFLGPRATFTHLATMQHFGLAAELVAQKSIPAVFEEVEKGRALYGVVPVENSTEGMVSHTLDMFMESDL
KINAEVLLEVSHDLLSRTGRLDDVKKVYSHPQALAQCRKWLDDNLPGVPVVDVASTALAAQIVSEDYAAAAIASEFAAAQ
YDLKVVRTRIEDQVNNFTRFLVIGRKMADRSGDDKTSLMFSVKDEPGILYRMLEPFASRGVNLSKIESRPLKKKAWEYIF
YLDLAGHITDPVVAEAVQDLGRYCQFVKILGSYPRAK

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=382, Percent_Identity=32.9842931937173, Blast_Score=187, Evalue=7e-49,
Organism=Saccharomyces cerevisiae, GI6324013, Length=345, Percent_Identity=26.6666666666667, Blast_Score=109, Evalue=5e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 39921; Mature: 39790

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSATRNLDALRREIDAIDDAILDLLNRRAGLVMEVGQVKTVEKRDFHVPNREREIYERLL
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCCCHHHHHHHHHH
AHNTGPFPAEAVKSVFREIISASLALEAPMKVAFLGPRATFTHLATMQHFGLAAELVAQK
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
SIPAVFEEVEKGRALYGVVPVENSTEGMVSHTLDMFMESDLKINAEVLLEVSHDLLSRTG
CCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
RLDDVKKVYSHPQALAQCRKWLDDNLPGVPVVDVASTALAAQIVSEDYAAAAIASEFAAA
CHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYDLKVVRTRIEDQVNNFTRFLVIGRKMADRSGDDKTSLMFSVKDEPGILYRMLEPFASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHC
GVNLSKIESRPLKKKAWEYIFYLDLAGHITDPVVAEAVQDLGRYCQFVKILGSYPRAK
CCCHHHHHCCCHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SATRNLDALRREIDAIDDAILDLLNRRAGLVMEVGQVKTVEKRDFHVPNREREIYERLL
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHCCCCCCHHHHHHHHHH
AHNTGPFPAEAVKSVFREIISASLALEAPMKVAFLGPRATFTHLATMQHFGLAAELVAQK
HCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
SIPAVFEEVEKGRALYGVVPVENSTEGMVSHTLDMFMESDLKINAEVLLEVSHDLLSRTG
CCHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCC
RLDDVKKVYSHPQALAQCRKWLDDNLPGVPVVDVASTALAAQIVSEDYAAAAIASEFAAA
CHHHHHHHHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QYDLKVVRTRIEDQVNNFTRFLVIGRKMADRSGDDKTSLMFSVKDEPGILYRMLEPFASR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHC
GVNLSKIESRPLKKKAWEYIFYLDLAGHITDPVVAEAVQDLGRYCQFVKILGSYPRAK
CCCHHHHHCCCHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]