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The map label for this gene is yqeV [H]

Identifier: 39997663

GI number: 39997663

Start: 2829875

End: 2831179

Strand: Reverse

Name: yqeV [H]

Synonym: GSU2568

Alternate gene names: 39997663

Gene position: 2831179-2829875 (Counterclockwise)

Preceding gene: 308513324

Following gene: 39997661

Centisome position: 74.23

GC content: 67.97

Gene sequence:

>1305_bases
ATGCAGCGGGTTGCCATCACCACCCTCGGCTGCAAGATCAACCAGTTCGAATCAGCTGCCATGACCGAAAGCCTCGGTCG
CGAGGGGTTCCGGCTGGTTCCCTTCGAGGACGAGGCGGATATCTACGTCATCAACACCTGCACGGTCACGGCACGGACCG
ACGCGGAGTCGCGGCGGCTCATCCGCCGGGCCATGCGCAGGAACCCGGCTGCCCGGGTGGTGGTGACCGGCTGTTATGCC
CAGGTGGCGCCCGACGCGGTGGGTGAGCTGCCCGGCGTGTCGCTGGTGGTGGGGAACAGCGAGAAGAAGGGGATCGCCGG
GCTGTTGCGGGATGCGGTGCCGGCGGAAAAGATCCTGGTGTCGGACATCTCCCGGCAGCGGACCGTGGAGGCCCTGGGGC
TGGAGAGCTTTGCGGAGCATACCCGCGCGTTCCTCCAGGTGCAGAACGGCTGCGACGCCTTCTGCTCCTACTGCATCGTG
CCCCATGCCCGGGGGAGGAGTCGCAGCGTGCCCTTCCGGGACGTGCTGGAGGGGATCGGCACCTTTGCCTACCAGGGATT
CCGGGAGGTGGTGCTGACCGGCATCCATCTGGGGGCCTACGGCGCCGACCTGGAGCCCCCCGCGAGCCTTCTCGATCTGC
TGGAGGCTGCCGACGCCGAGGCGCTGGTGCCGCGTCTGCGCGTCGGGTCGGTGGAGCCCCACGAGATCTCCGACGGTCTC
ATCGCCCTGATGGCCCGGTCGCCCGTCATCTGTCCCCATCTGCACATCCCTCTCCAAAGCGGCTCTGACAGCGTGCTGGA
GCGGATGAACCGCCGGTACACGGCCGCGTTTTTCCGGGAGCGGGTGGAACGGCTGGCTGCGGCGGTGCCGGACATCTGCA
TCGGCTGCGACGTGATCGCCGGCTTCCCCGGCGAGACGGACGAGGAGTTTGCCGCCACCCTGGCCCTGCTGGAGGGGCTC
CCCATCGCCCACCTCCACGTCTTTCCCTTTTCGCGGCGCGAGGGAACACCCGCGGCTCGCATGCCCGGCCAGGTGGACGG
CAAAATTGTGCGGGAGCGTGCCGAGGTCCTGCGGGCGCTGTCCGACCGGAAGCGGGAGACCTTTCACCGGCGCTTCATGG
GACGGGATCTGCCGGTGCTGGTGTTGAACGGCCGGGGAAAAGAGGTGACGGGGCTGTCGCGCAACTACATTACGGTGCGG
ATCGAGGCGGTGACGCCGCCCCCCGAGGGTGAGGTCATGGTCCGGATAACCGGCGTGGAGGCCGACGGGGTGCGGGGCAT
TATCTCAGAACCTGTCCGTAAGTAA

Upstream 100 bases:

>100_bases
GGTTCCGGCAGCCCGAGAAGTCGGTGACCCCGGGGCAGGCGGTGGTCTTCTACCGCGATGACGAGGTTCTGGGCGGCGGC
TGGATCGAGGGGCGGCTGTG

Downstream 100 bases:

>100_bases
TCACTCCGGTTTCGCATTCCGTCTTCATGCCGTTTTGGGCCGGCCTTCAATCGTACCGTCCTCGACGAAGCCCTGCTACG
CCTGCGGCGCTACTCAATCG

Product: MiaB-like tRNA modifying enzyme

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MQRVAITTLGCKINQFESAAMTESLGREGFRLVPFEDEADIYVINTCTVTARTDAESRRLIRRAMRRNPAARVVVTGCYA
QVAPDAVGELPGVSLVVGNSEKKGIAGLLRDAVPAEKILVSDISRQRTVEALGLESFAEHTRAFLQVQNGCDAFCSYCIV
PHARGRSRSVPFRDVLEGIGTFAYQGFREVVLTGIHLGAYGADLEPPASLLDLLEAADAEALVPRLRVGSVEPHEISDGL
IALMARSPVICPHLHIPLQSGSDSVLERMNRRYTAAFFRERVERLAAAVPDICIGCDVIAGFPGETDEEFAATLALLEGL
PIAHLHVFPFSRREGTPAARMPGQVDGKIVRERAEVLRALSDRKRETFHRRFMGRDLPVLVLNGRGKEVTGLSRNYITVR
IEAVTPPPEGEVMVRITGVEADGVRGIISEPVRK

Sequences:

>Translated_434_residues
MQRVAITTLGCKINQFESAAMTESLGREGFRLVPFEDEADIYVINTCTVTARTDAESRRLIRRAMRRNPAARVVVTGCYA
QVAPDAVGELPGVSLVVGNSEKKGIAGLLRDAVPAEKILVSDISRQRTVEALGLESFAEHTRAFLQVQNGCDAFCSYCIV
PHARGRSRSVPFRDVLEGIGTFAYQGFREVVLTGIHLGAYGADLEPPASLLDLLEAADAEALVPRLRVGSVEPHEISDGL
IALMARSPVICPHLHIPLQSGSDSVLERMNRRYTAAFFRERVERLAAAVPDICIGCDVIAGFPGETDEEFAATLALLEGL
PIAHLHVFPFSRREGTPAARMPGQVDGKIVRERAEVLRALSDRKRETFHRRFMGRDLPVLVLNGRGKEVTGLSRNYITVR
IEAVTPPPEGEVMVRITGVEADGVRGIISEPVRK
>Mature_434_residues
MQRVAITTLGCKINQFESAAMTESLGREGFRLVPFEDEADIYVINTCTVTARTDAESRRLIRRAMRRNPAARVVVTGCYA
QVAPDAVGELPGVSLVVGNSEKKGIAGLLRDAVPAEKILVSDISRQRTVEALGLESFAEHTRAFLQVQNGCDAFCSYCIV
PHARGRSRSVPFRDVLEGIGTFAYQGFREVVLTGIHLGAYGADLEPPASLLDLLEAADAEALVPRLRVGSVEPHEISDGL
IALMARSPVICPHLHIPLQSGSDSVLERMNRRYTAAFFRERVERLAAAVPDICIGCDVIAGFPGETDEEFAATLALLEGL
PIAHLHVFPFSRREGTPAARMPGQVDGKIVRERAEVLRALSDRKRETFHRRFMGRDLPVLVLNGRGKEVTGLSRNYITVR
IEAVTPPPEGEVMVRITGVEADGVRGIISEPVRK

Specific function: Unknown

COG id: COG0621

COG function: function code J; 2-methylthioadenine synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 TRAM domain [H]

Homologues:

Organism=Homo sapiens, GI93277076, Length=373, Percent_Identity=30.5630026809651, Blast_Score=169, Evalue=3e-42,
Organism=Homo sapiens, GI28872782, Length=478, Percent_Identity=25.9414225941423, Blast_Score=147, Evalue=2e-35,
Organism=Homo sapiens, GI28872784, Length=476, Percent_Identity=26.0504201680672, Blast_Score=147, Evalue=2e-35,
Organism=Escherichia coli, GI1786882, Length=439, Percent_Identity=31.4350797266515, Blast_Score=197, Evalue=9e-52,
Organism=Escherichia coli, GI1787057, Length=392, Percent_Identity=27.8061224489796, Blast_Score=140, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17553146, Length=437, Percent_Identity=28.1464530892449, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71996771, Length=354, Percent_Identity=29.6610169491525, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI19922432, Length=371, Percent_Identity=31.5363881401617, Blast_Score=155, Evalue=3e-38,
Organism=Drosophila melanogaster, GI21356207, Length=466, Percent_Identity=28.1115879828326, Blast_Score=151, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006638
- InterPro:   IPR005839
- InterPro:   IPR020612
- InterPro:   IPR013848
- InterPro:   IPR006467
- InterPro:   IPR007197
- InterPro:   IPR002792 [H]

Pfam domain/function: PF04055 Radical_SAM; PF01938 TRAM; PF00919 UPF0004 [H]

EC number: NA

Molecular weight: Translated: 47396; Mature: 47396

Theoretical pI: Translated: 6.98; Mature: 6.98

Prosite motif: PS01278 UPF0004

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRVAITTLGCKINQFESAAMTESLGREGFRLVPFEDEADIYVINTCTVTARTDAESRRL
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEEEEEEECCCHHHHHH
IRRAMRRNPAARVVVTGCYAQVAPDAVGELPGVSLVVGNSEKKGIAGLLRDAVPAEKILV
HHHHHHCCCCCEEEEEECHHHHCCHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHH
SDISRQRTVEALGLESFAEHTRAFLQVQNGCDAFCSYCIVPHARGRSRSVPFRDVLEGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
TFAYQGFREVVLTGIHLGAYGADLEPPASLLDLLEAADAEALVPRLRVGSVEPHEISDGL
HHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHCCHH
IALMARSPVICPHLHIPLQSGSDSVLERMNRRYTAAFFRERVERLAAAVPDICIGCDVIA
HHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHEE
GFPGETDEEFAATLALLEGLPIAHLHVFPFSRREGTPAARMPGQVDGKIVRERAEVLRAL
CCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHCCCCCCCHHHHHHHHHHHHHH
SDRKRETFHRRFMGRDLPVLVLNGRGKEVTGLSRNYITVRIEAVTPPPEGEVMVRITGVE
HHHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCCEEEEEEEEECCCCCCCEEEEEECCC
ADGVRGIISEPVRK
CCCCCCHHHCCCCC
>Mature Secondary Structure
MQRVAITTLGCKINQFESAAMTESLGREGFRLVPFEDEADIYVINTCTVTARTDAESRRL
CCEEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCCCCEEEEEEEEEEECCCHHHHHH
IRRAMRRNPAARVVVTGCYAQVAPDAVGELPGVSLVVGNSEKKGIAGLLRDAVPAEKILV
HHHHHHCCCCCEEEEEECHHHHCCHHHHCCCCEEEEECCCCCCHHHHHHHHCCCHHHHHH
SDISRQRTVEALGLESFAEHTRAFLQVQNGCDAFCSYCIVPHARGRSRSVPFRDVLEGIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCHHHHHHHHH
TFAYQGFREVVLTGIHLGAYGADLEPPASLLDLLEAADAEALVPRLRVGSVEPHEISDGL
HHHHHHHHHHHHHHHEECCCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCCCCHHCCHH
IALMARSPVICPHLHIPLQSGSDSVLERMNRRYTAAFFRERVERLAAAVPDICIGCDVIA
HHHHHCCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCCHHEE
GFPGETDEEFAATLALLEGLPIAHLHVFPFSRREGTPAARMPGQVDGKIVRERAEVLRAL
CCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCHHCCCCCCCHHHHHHHHHHHHHH
SDRKRETFHRRFMGRDLPVLVLNGRGKEVTGLSRNYITVRIEAVTPPPEGEVMVRITGVE
HHHHHHHHHHHHHCCCCCEEEECCCCCEECCCCCCEEEEEEEEECCCCCCCEEEEEECCC
ADGVRGIISEPVRK
CCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8969508; 9023197; 9384377 [H]