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The map label for this gene is mrpC [H]

Identifier: 39997439

GI number: 39997439

Start: 2560414

End: 2560776

Strand: Reverse

Name: mrpC [H]

Synonym: GSU2342

Alternate gene names: 39997439

Gene position: 2560776-2560414 (Counterclockwise)

Preceding gene: 39997440

Following gene: 39997438

Centisome position: 67.14

GC content: 65.84

Gene sequence:

>363_bases
GTGGAAAGCGTTCTGGCAATCGTCATCGGCGGGCTGTACGCGACGGGGCTCTACCTCATGGTGCGGCGGAGCATCGTCAA
GATGATCTTCGGCCTGGCCCTCCTGGGGAATGCGGCCAATCTTCTCATCTTCACCGTGGGACGCCTCACCCGCGGGCGGC
CTCCCTACGTGCCGGCCGGCGGCACCGAGCCGATTCCGCCGGTGGCCGACCCGCTGCCCCAGGCCCTGATCCTGACCGCC
ATCGTCATCGGCTTCGGGGTGCAGGCCTTTGCCCTGGTCCTGATCAAGCGGGTCTACCAGACCGTGGGCACCGACGATCT
GGACGAGATGACCACGACCGATACCGAGTACCGGAGCAATTGA

Upstream 100 bases:

>100_bases
CATCGGTCACGGGGGCACGCCGATCCTGTTCGACATCGGAGTCTACCTGGTGGTGGCGGGGATGGCGCTCATGATCGTGT
TCAGCCTGATGGAGGAATAG

Downstream 100 bases:

>100_bases
TGAAACTTCTTCTCTTCCTCCCCCTCATCATCCCGCTGGCCACGGCTGTGGCGGGGCTTTTCGCCTGGAACCGGCGGGAG
CTCCAACGGCTGTTGGGCGT

Product: monovalent cation/H+ antiporter subunit C

Products: NA

Alternate protein names: Mrp complex subunit C; Multiple resistance and pH homeostasis protein C [H]

Number of amino acids: Translated: 120; Mature: 120

Protein sequence:

>120_residues
MESVLAIVIGGLYATGLYLMVRRSIVKMIFGLALLGNAANLLIFTVGRLTRGRPPYVPAGGTEPIPPVADPLPQALILTA
IVIGFGVQAFALVLIKRVYQTVGTDDLDEMTTTDTEYRSN

Sequences:

>Translated_120_residues
MESVLAIVIGGLYATGLYLMVRRSIVKMIFGLALLGNAANLLIFTVGRLTRGRPPYVPAGGTEPIPPVADPLPQALILTA
IVIGFGVQAFALVLIKRVYQTVGTDDLDEMTTTDTEYRSN
>Mature_120_residues
MESVLAIVIGGLYATGLYLMVRRSIVKMIFGLALLGNAANLLIFTVGRLTRGRPPYVPAGGTEPIPPVADPLPQALILTA
IVIGFGVQAFALVLIKRVYQTVGTDDLDEMTTTDTEYRSN

Specific function: Mnh complex is a Na(+)Li(+)/H(+) antiporter involved in Na(+) and/or Li(+) excretion and Na(+) resistance. Na(+)/H(+) antiport consumes a transmembrane electrical potential, and is thus inferred to be electrogenic. Does not transport K(+), Ca(2+) or Mg(2+

COG id: COG1006

COG function: function code P; Multisubunit Na+/H+ antiporter, MnhC subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CPA3 antiporters (TC 2.A.63) subunit C family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001133 [H]

Pfam domain/function: PF00420 Oxidored_q2 [H]

EC number: NA

Molecular weight: Translated: 12864; Mature: 12864

Theoretical pI: Translated: 6.75; Mature: 6.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MESVLAIVIGGLYATGLYLMVRRSIVKMIFGLALLGNAANLLIFTVGRLTRGRPPYVPAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
GTEPIPPVADPLPQALILTAIVIGFGVQAFALVLIKRVYQTVGTDDLDEMTTTDTEYRSN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHCCC
>Mature Secondary Structure
MESVLAIVIGGLYATGLYLMVRRSIVKMIFGLALLGNAANLLIFTVGRLTRGRPPYVPAG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCC
GTEPIPPVADPLPQALILTAIVIGFGVQAFALVLIKRVYQTVGTDDLDEMTTTDTEYRSN
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11356194 [H]