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The map label for this gene is lolC [H]

Identifier: 39997368

GI number: 39997368

Start: 2486037

End: 2487308

Strand: Reverse

Name: lolC [H]

Synonym: GSU2270

Alternate gene names: 39997368

Gene position: 2487308-2486037 (Counterclockwise)

Preceding gene: 39997369

Following gene: 39997367

Centisome position: 65.21

GC content: 58.25

Gene sequence:

>1272_bases
ATGCCCTACGAGTTATTTATCGGTCTCCGCTATCTGAAGGCCAAGCGGAAGTCGACCTTCATATCGATCATCACCTTTAT
TTCCACCGCGGGCGTTGCCCTGGGGGTCCTTGCGCTTATCGTCGTTCTGGCGGTGATGACCGGCTTCGAAGAAGATCTCA
AGGAAAAGATCCTCGGCACCAACGCCCACATCGTGGTGCTGAAATCGAGCGGCGGCATCGAGGACTATCACGCCATGATG
GAGCGGCTTAGTGCCGTCAAAGGGGTTAAGGCCGTCACCCCATTCATCTACAGCCAAGTGATGCTTTCCTCGGGCGGCAA
CGTTTCCGGTGTGGTGCTCAGGGGGGTCGATCCCGCCACTGATCCCCAGGTCACCAATCTCTCCCGTTCCCTCGTCGACG
GCAAACTGACCGATCTCACTACTGTCCCGGCCCCTCTGGCCTCGGCCGAGCCGGTCCGGCCCGGCATCATCATCGGCAAG
GAGCTGGCGCGTTCCCTCAACCTGTACGTGGGCGACACCCTGAACGTCATCTCTCCCCTCGGCAACATTACCCCCCTCGG
CATGGTTCCCAAGATGAAGCAGTTCCGGGTGGTCGGACTCTTCAACACCGGCATGTTCGAGTATGATTCGACCCTGGCCT
ACGTGGGGCTCGGCGAGGCCCAGGAGTTTCTTTCGATGGGGAAAGCGGTCACCGGTATCCAGCTCCGGGTTGCCGATGTC
TACCACACGGGAGAGATGGTGCGGGAGATCAACCGTGACCTCGGATTCCCTTACTATGCCCGGGATTGGATGCAGATGAA
CAAGAACATTCTTTTTGCCTTGAAGACCGAAAAGATGGTAATGTTCATCATTCTGACCCTGATCGTCCTGGTGGCCGCTT
TCGGCATCGCCTCGACCCTCTTCATGGTGGTCATGGAGAAGACAAAGGATATCGCCATCCTCAAATCCATGGGGGCGACA
GGGCGGAGCATCATGAAGATTTTCGTTCTCGAAGGGCTCATCATCGGCATCTCCGGGACGGCCATCGGCGTTATCGGCGG
ACTTCTTGTGGCGCTGAACCTGGAGCCCATCGTCGGAGTCATCCAGCGGGTCACCGGTTTCGAGTTGTTCAGCAAGGACG
TTTACTACCTGGATCATTTTCCGTCCCAGGTCGTGCCGTCCGACGTACTGCTCATCTCGGTGACGGCCGTGATTATCTCA
CTGGTGGCGACCCTCTACCCGTCCTGGCAGGCATCACGCCTCCCCCCGGCCGAGGCGTTGCGCTATGAGTAA

Upstream 100 bases:

>100_bases
TCCGCAACTACGCAAGGAAAAATAAGAAAACCGGGTCCAGGGGCCGGAGAACGGCAGGCGGATTTCTCCCGGTCCCCGAT
TTCCGGTTCCGGATGCACCC

Downstream 100 bases:

>100_bases
CCTCATCGAGGTTGTGGACCTCTGCAAGACCTACGGCGCCGGGGACACTCGCGTCGATGTGCTCAGGGGGGTCAATCTGG
CGGTTGCCGAAGGGGAAACC

Product: ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MPYELFIGLRYLKAKRKSTFISIITFISTAGVALGVLALIVVLAVMTGFEEDLKEKILGTNAHIVVLKSSGGIEDYHAMM
ERLSAVKGVKAVTPFIYSQVMLSSGGNVSGVVLRGVDPATDPQVTNLSRSLVDGKLTDLTTVPAPLASAEPVRPGIIIGK
ELARSLNLYVGDTLNVISPLGNITPLGMVPKMKQFRVVGLFNTGMFEYDSTLAYVGLGEAQEFLSMGKAVTGIQLRVADV
YHTGEMVREINRDLGFPYYARDWMQMNKNILFALKTEKMVMFIILTLIVLVAAFGIASTLFMVVMEKTKDIAILKSMGAT
GRSIMKIFVLEGLIIGISGTAIGVIGGLLVALNLEPIVGVIQRVTGFELFSKDVYYLDHFPSQVVPSDVLLISVTAVIIS
LVATLYPSWQASRLPPAEALRYE

Sequences:

>Translated_423_residues
MPYELFIGLRYLKAKRKSTFISIITFISTAGVALGVLALIVVLAVMTGFEEDLKEKILGTNAHIVVLKSSGGIEDYHAMM
ERLSAVKGVKAVTPFIYSQVMLSSGGNVSGVVLRGVDPATDPQVTNLSRSLVDGKLTDLTTVPAPLASAEPVRPGIIIGK
ELARSLNLYVGDTLNVISPLGNITPLGMVPKMKQFRVVGLFNTGMFEYDSTLAYVGLGEAQEFLSMGKAVTGIQLRVADV
YHTGEMVREINRDLGFPYYARDWMQMNKNILFALKTEKMVMFIILTLIVLVAAFGIASTLFMVVMEKTKDIAILKSMGAT
GRSIMKIFVLEGLIIGISGTAIGVIGGLLVALNLEPIVGVIQRVTGFELFSKDVYYLDHFPSQVVPSDVLLISVTAVIIS
LVATLYPSWQASRLPPAEALRYE
>Mature_422_residues
PYELFIGLRYLKAKRKSTFISIITFISTAGVALGVLALIVVLAVMTGFEEDLKEKILGTNAHIVVLKSSGGIEDYHAMME
RLSAVKGVKAVTPFIYSQVMLSSGGNVSGVVLRGVDPATDPQVTNLSRSLVDGKLTDLTTVPAPLASAEPVRPGIIIGKE
LARSLNLYVGDTLNVISPLGNITPLGMVPKMKQFRVVGLFNTGMFEYDSTLAYVGLGEAQEFLSMGKAVTGIQLRVADVY
HTGEMVREINRDLGFPYYARDWMQMNKNILFALKTEKMVMFIILTLIVLVAAFGIASTLFMVVMEKTKDIAILKSMGATG
RSIMKIFVLEGLIIGISGTAIGVIGGLLVALNLEPIVGVIQRVTGFELFSKDVYYLDHFPSQVVPSDVLLISVTAVIISL
VATLYPSWQASRLPPAEALRYE

Specific function: Part of an ATP-dependent transport system responsible for the release of lipoproteins targeted to the outer membrane from the inner membrane. Such a release is dependent of the sorting-signal (absence of an Asp at position 2 of the mature lipoprotein) and

COG id: COG4591

COG function: function code M; ABC-type transport system, involved in lipoprotein release, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. LolC/E subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787362, Length=420, Percent_Identity=32.6190476190476, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787360, Length=430, Percent_Identity=34.4186046511628, Blast_Score=193, Evalue=1e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838
- InterPro:   IPR011925 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 45847; Mature: 45716

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPYELFIGLRYLKAKRKSTFISIITFISTAGVALGVLALIVVLAVMTGFEEDLKEKILGT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
NAHIVVLKSSGGIEDYHAMMERLSAVKGVKAVTPFIYSQVMLSSGGNVSGVVLRGVDPAT
CCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
DPQVTNLSRSLVDGKLTDLTTVPAPLASAEPVRPGIIIGKELARSLNLYVGDTLNVISPL
CCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCEEECHHHHHHHCCCCCCHHHHHHHC
GNITPLGMVPKMKQFRVVGLFNTGMFEYDSTLAYVGLGEAQEFLSMGKAVTGIQLRVADV
CCCCCCCCCCCCHHEEEEEEEECCCEEECCCEEEEECCHHHHHHHHCCHHCCEEEEEEHH
YHTGEMVREINRDLGFPYYARDWMQMNKNILFALKTEKMVMFIILTLIVLVAAFGIASTL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
FMVVMEKTKDIAILKSMGATGRSIMKIFVLEGLIIGISGTAIGVIGGLLVALNLEPIVGV
HHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCHHHHHH
IQRVTGFELFSKDVYYLDHFPSQVVPSDVLLISVTAVIISLVATLYPSWQASRLPPAEAL
HHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHC
RYE
CCC
>Mature Secondary Structure 
PYELFIGLRYLKAKRKSTFISIITFISTAGVALGVLALIVVLAVMTGFEEDLKEKILGT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCC
NAHIVVLKSSGGIEDYHAMMERLSAVKGVKAVTPFIYSQVMLSSGGNVSGVVLRGVDPAT
CCEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCC
DPQVTNLSRSLVDGKLTDLTTVPAPLASAEPVRPGIIIGKELARSLNLYVGDTLNVISPL
CCCHHHHHHHHHCCCCCCCEECCCCCCCCCCCCCCEEECHHHHHHHCCCCCCHHHHHHHC
GNITPLGMVPKMKQFRVVGLFNTGMFEYDSTLAYVGLGEAQEFLSMGKAVTGIQLRVADV
CCCCCCCCCCCCHHEEEEEEEECCCEEECCCEEEEECCHHHHHHHHCCHHCCEEEEEEHH
YHTGEMVREINRDLGFPYYARDWMQMNKNILFALKTEKMVMFIILTLIVLVAAFGIASTL
HHHHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHH
FMVVMEKTKDIAILKSMGATGRSIMKIFVLEGLIIGISGTAIGVIGGLLVALNLEPIVGV
HHHHHHHCCHHHHHHHCCCCHHHHHHHHHHHCEEEEECCHHHHHHHHHHHHHCCHHHHHH
IQRVTGFELFSKDVYYLDHFPSQVVPSDVLLISVTAVIISLVATLYPSWQASRLPPAEAL
HHHHHHHHHHHCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHC
RYE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]