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The map label for this gene is mreB [H]

Identifier: 39997187

GI number: 39997187

Start: 2294930

End: 2295973

Strand: Reverse

Name: mreB [H]

Synonym: GSU2089

Alternate gene names: 39997187

Gene position: 2295973-2294930 (Counterclockwise)

Preceding gene: 39997190

Following gene: 39997186

Centisome position: 60.2

GC content: 62.64

Gene sequence:

>1044_bases
ATGCTCAAGATATTCGACAGCCTTTTCGGCTTGTTTTCCAATGACCTGGCAATCGACCTCGGCACCGCCAACACCCTCGT
TTACCTGAAGGGGAAGGGGATCGTGGTGCGTGAGCCGTCCGTCGTGGCGGTGCAGAAGACCAATATGGGCCAGCAGAAGG
TGCTGGCGGTGGGGATGGAAGCCAAGAAGATGCTCGGCCGCACGCCGGGCAACATCACCGCCATCCGCCCCATGAAGGAC
GGCGTCATCGCCGATTTCGACATCACCGAGGAGATGCTCCGCTACTTCATCCATAAGGTTCACAACCGCAAGACCCTGGT
TCGTCCCCGGATCGTCATCTGCGTTCCCTCGGGGATCACCCAGGTGGAGAAGCGGGCCGTCAAGGAGTCGGCCGAGTCGG
CCGGCGCCCGTGAAGTCTATCTGATCGAGGAGCCCATGGCGGCAGCCATCGGCGCAGGCCTTCCCATTACCGAGGCGAGC
GGCAACATGATCGTCGATATCGGCGGCGGCACCACCGAGGTGGCGGTCATCTCGCTGGCAGGCATCGTGCTCACCAAGTC
GGTACGGGTCGGCGGCGACAAGATGGACGAGGCCATTGTCCAGTACATCAAGCGCAAGTACAATCTCCTCATCGGCGACC
GCATGGCCGAGATCATCAAGATCGAGATCGGCGAAGCCTATGCCGCCGGCGAGATGCGGACCATGGAGGTCAAGGGGCGG
GACCTGGTGTCCGGCATTCCCAAGACCACTGAGATCAATTCGGACGAGATTCGTGAGGCCCTGTCCGAGCCGGTCAATGC
CATCGTGGACGCCGTCAAGATCTGCCTTGAGCGGACCCCCCCCGAGCTTGCCGCCGATATCGTGGACCGGGGAATCTTCC
TGGCCGGCGGCGGTGCCCTTCTGCGTAACCTGGACATGCTCCTGCGCGAAGAGACGGGGCTGCCGGTCTTCATCGCCGAC
GACCCTCTCTCCTGCGTCGTTCTCGGTTCCGGCAAGGTTCTCGACGAGCTGAACCTGCTCCGCCGGGTCGCCGTCAGCTC
CTGA

Upstream 100 bases:

>100_bases
CCGGCGCTTTTCCCCCTTGCACGCTGGATGGGTTTCTGCTACGATTCAGCGCTTCAAAAACGTCATTCCCCCTTTGCATG
CGTGAAAGGATTCAGAGTCC

Downstream 100 bases:

>100_bases
CCGGACGCCGTCCCCCCGGACGCATACACATTGTTTGCACGGCCGCACCTCACCCGATGTGCGGCCGTGCCGTCATCCCC
TCTATCCAGTCACACGGCAG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 347; Mature: 347

Protein sequence:

>347_residues
MLKIFDSLFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNMGQQKVLAVGMEAKKMLGRTPGNITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVLTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRMAEIIKIEIGEAYAAGEMRTMEVKGR
DLVSGIPKTTEINSDEIREALSEPVNAIVDAVKICLERTPPELAADIVDRGIFLAGGGALLRNLDMLLREETGLPVFIAD
DPLSCVVLGSGKVLDELNLLRRVAVSS

Sequences:

>Translated_347_residues
MLKIFDSLFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNMGQQKVLAVGMEAKKMLGRTPGNITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVLTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRMAEIIKIEIGEAYAAGEMRTMEVKGR
DLVSGIPKTTEINSDEIREALSEPVNAIVDAVKICLERTPPELAADIVDRGIFLAGGGALLRNLDMLLREETGLPVFIAD
DPLSCVVLGSGKVLDELNLLRRVAVSS
>Mature_347_residues
MLKIFDSLFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNMGQQKVLAVGMEAKKMLGRTPGNITAIRPMKD
GVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGITQVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEAS
GNMIVDIGGGTTEVAVISLAGIVLTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRMAEIIKIEIGEAYAAGEMRTMEVKGR
DLVSGIPKTTEINSDEIREALSEPVNAIVDAVKICLERTPPELAADIVDRGIFLAGGGALLRNLDMLLREETGLPVFIAD
DPLSCVVLGSGKVLDELNLLRRVAVSS

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=341, Percent_Identity=62.4633431085044, Blast_Score=433, Evalue=1e-123,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37383; Mature: 37383

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIFDSLFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNMGQQKVLAVGME
CHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCHHHHHHHCHH
AKKMLGRTPGNITAIRPMKDGVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGIT
HHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCHH
QVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEASGNMIVDIGGGTTEVAVISLA
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCHHHHHHHHH
GIVLTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRMAEIIKIEIGEAYAAGEMRTMEVKGR
HHHHHHCEECCCCHHHHHHHHHHHHHHCCHHHHHHEEEEEEEECCEEECCCEEEEEECCC
DLVSGIPKTTEINSDEIREALSEPVNAIVDAVKICLERTPPELAADIVDRGIFLAGGGAL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHH
LRNLDMLLREETGLPVFIADDPLSCVVLGSGKVLDELNLLRRVAVSS
HHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MLKIFDSLFGLFSNDLAIDLGTANTLVYLKGKGIVVREPSVVAVQKTNMGQQKVLAVGME
CHHHHHHHHHHHCCCEEEEECCCCEEEEEECCEEEEECCCEEEEEECCCCHHHHHHHCHH
AKKMLGRTPGNITAIRPMKDGVIADFDITEEMLRYFIHKVHNRKTLVRPRIVICVPSGIT
HHHHHCCCCCCEEEEEECCCCEEECCHHHHHHHHHHHHHHHCCCEECCCEEEEECCCCHH
QVEKRAVKESAESAGAREVYLIEEPMAAAIGAGLPITEASGNMIVDIGGGTTEVAVISLA
HHHHHHHHHHHHCCCCEEEEEECCCHHHHHCCCCCEEECCCCEEEEECCCCHHHHHHHHH
GIVLTKSVRVGGDKMDEAIVQYIKRKYNLLIGDRMAEIIKIEIGEAYAAGEMRTMEVKGR
HHHHHHCEECCCCHHHHHHHHHHHHHHCCHHHHHHEEEEEEEECCEEECCCEEEEEECCC
DLVSGIPKTTEINSDEIREALSEPVNAIVDAVKICLERTPPELAADIVDRGIFLAGGGAL
HHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCEEEECCHHH
LRNLDMLLREETGLPVFIADDPLSCVVLGSGKVLDELNLLRRVAVSS
HHHHHHHHHHCCCCEEEEECCCCEEEEECCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]