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The map label for this gene is resD [H]

Identifier: 39997144

GI number: 39997144

Start: 2244947

End: 2246161

Strand: Reverse

Name: resD [H]

Synonym: GSU2046

Alternate gene names: 39997144

Gene position: 2246161-2244947 (Counterclockwise)

Preceding gene: 39997145

Following gene: 39997143

Centisome position: 58.89

GC content: 61.98

Gene sequence:

>1215_bases
ATGGGCAACAGGCTGCTCCTCGCCGACGACAGCATCACCATTCAGAAGGTCGTGGGAATCATCTTCGCCAACGAAGATTT
TGAGCTGACCGTTGTCGACAACGGCGACGCCGCGCTGGAAAAAGCCCGTGAAAGCAGACCCGATGTGATGCTTATCGACG
CCCTCATGCCCGGCTCCAATGGCTATGAGGTGTGCGCCGCCGTCCGGCAAGACCCCGCCCTGAAGAACACGCCTCTCCTG
CTCATGACCGGCGCCTTCGAGCCCTTTGACGAGGACCGGGCCCGGCAGTGCGGCGCGGACGACTTTATCTCAAAACCCTT
TGAATCCCAGCAGCTTGTCGACAAAGTCAAGGAGCTTCTGGCTCTGGGAGGCTCACGTGCGGTAACGGGCGCAGGCGCTG
CACCGGATTTTGCCGCAGAAATTCCTGCCGCCGTCTTCGAGGTGGAGCCGGAGTCGTTCGTTTCTTCCCCCGAGCCGTCA
GCCGTCTTCGAGCCGGCCACACCCGAGCCGTTTCCGGTGTTCGAGTCGGAGCCCCTGGCTGAACCCGCTGGAGAGGCTGC
GGCGCAGGCAGTGACATTCGAAGCTGAAGGGACCGTTCCCGCCGATGATCTGTGGGGAGCCTTCGAGCTTGAGGAGGAAG
TTGCTGGCGAGGTTGAAGTCGGTGAGATGGTGCCCGGAGACGAGGCAATGGGAGAGGTGTTCGATGCCGCGGCCTTTGCT
GCAGCGCCTGCCGCCTCTGCCGATTCAGGCACGTTCGGTGTGCCTGTGGAAGAATTCACCTTCACCGAAGAACCCGCGTT
CGGTACAGTCGAGGAGACGATAAGCTTCGGCGCGGTGGCCGAACCCGAGTCCTTTGCCTTTGAACCCGAGCCGACGGCCG
GTGTTCAGGCTGCCGAGGCCTTTGCAGCGGAACCGGCGGCTGGCTTTGAGTTCGGCGGGACTGCCGTACCGGAGCAGTTT
GTCGTGGAACAGCAGTTCGCCCCTGATGAAGAATATGTCTCCGCCGTCCCTCCGGCTGCTTCCACGTCAGTGGCGCCGGT
TGTCGAGCCGGTTGCCCCGGGCTCGGGGACCATCACCCTCACCGAAGAACAACTGGCTGCCGCCATTTCCCGTATCTCCC
GCGAAGTAATCGAGCGGATCGCTTGGGAAGTGGTGCCCGAACTGGCGGAAACGATCATCAAGGAAGAGATCCGCAAGATC
AAGGAAGGACTCTAG

Upstream 100 bases:

>100_bases
GGTCAGTATGGTAGCGTTTCCGCGATTGTTCGCGGGTTAACCGCACTTTTCCCCATCCATCCGGGGCCCCTTTTCCGACG
CTCCCCCTGAAGGAGGATTC

Downstream 100 bases:

>100_bases
GACGTACTTCAGGGCCGGCCCACGGGACCGGTCCACACCGCTGAAACTGAAATGGGGATGCTTCATCCCCATTTTTATTT
TGAAAAAAGAAGAGGTTAAT

Product: response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 404; Mature: 403

Protein sequence:

>404_residues
MGNRLLLADDSITIQKVVGIIFANEDFELTVVDNGDAALEKARESRPDVMLIDALMPGSNGYEVCAAVRQDPALKNTPLL
LMTGAFEPFDEDRARQCGADDFISKPFESQQLVDKVKELLALGGSRAVTGAGAAPDFAAEIPAAVFEVEPESFVSSPEPS
AVFEPATPEPFPVFESEPLAEPAGEAAAQAVTFEAEGTVPADDLWGAFELEEEVAGEVEVGEMVPGDEAMGEVFDAAAFA
AAPAASADSGTFGVPVEEFTFTEEPAFGTVEETISFGAVAEPESFAFEPEPTAGVQAAEAFAAEPAAGFEFGGTAVPEQF
VVEQQFAPDEEYVSAVPPAASTSVAPVVEPVAPGSGTITLTEEQLAAAISRISREVIERIAWEVVPELAETIIKEEIRKI
KEGL

Sequences:

>Translated_404_residues
MGNRLLLADDSITIQKVVGIIFANEDFELTVVDNGDAALEKARESRPDVMLIDALMPGSNGYEVCAAVRQDPALKNTPLL
LMTGAFEPFDEDRARQCGADDFISKPFESQQLVDKVKELLALGGSRAVTGAGAAPDFAAEIPAAVFEVEPESFVSSPEPS
AVFEPATPEPFPVFESEPLAEPAGEAAAQAVTFEAEGTVPADDLWGAFELEEEVAGEVEVGEMVPGDEAMGEVFDAAAFA
AAPAASADSGTFGVPVEEFTFTEEPAFGTVEETISFGAVAEPESFAFEPEPTAGVQAAEAFAAEPAAGFEFGGTAVPEQF
VVEQQFAPDEEYVSAVPPAASTSVAPVVEPVAPGSGTITLTEEQLAAAISRISREVIERIAWEVVPELAETIIKEEIRKI
KEGL
>Mature_403_residues
GNRLLLADDSITIQKVVGIIFANEDFELTVVDNGDAALEKARESRPDVMLIDALMPGSNGYEVCAAVRQDPALKNTPLLL
MTGAFEPFDEDRARQCGADDFISKPFESQQLVDKVKELLALGGSRAVTGAGAAPDFAAEIPAAVFEVEPESFVSSPEPSA
VFEPATPEPFPVFESEPLAEPAGEAAAQAVTFEAEGTVPADDLWGAFELEEEVAGEVEVGEMVPGDEAMGEVFDAAAFAA
APAASADSGTFGVPVEEFTFTEEPAFGTVEETISFGAVAEPESFAFEPEPTAGVQAAEAFAAEPAAGFEFGGTAVPEQFV
VEQQFAPDEEYVSAVPPAASTSVAPVVEPVAPGSGTITLTEEQLAAAISRISREVIERIAWEVVPELAETIIKEEIRKIK
EGL

Specific function: Member of the two-component regulatory system ResD/ResE. Required for the expression of resA, ctaA, qcrABC and fnr; activation role in global regulation of aerobic and anaerobic respiration [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=120, Percent_Identity=27.5, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1788394, Length=91, Percent_Identity=31.8681318681319, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1788550, Length=120, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1790860, Length=115, Percent_Identity=33.9130434782609, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 42451; Mature: 42320

Theoretical pI: Translated: 3.59; Mature: 3.59

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNRLLLADDSITIQKVVGIIFANEDFELTVVDNGDAALEKARESRPDVMLIDALMPGSN
CCCEEEEECCCEEHHHHHHHEEECCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCC
GYEVCAAVRQDPALKNTPLLLMTGAFEPFDEDRARQCGADDFISKPFESQQLVDKVKELL
CHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
ALGGSRAVTGAGAAPDFAAEIPAAVFEVEPESFVSSPEPSAVFEPATPEPFPVFESEPLA
HCCCCCEECCCCCCCCHHHHCCHHHEEECHHHHHCCCCCCCEECCCCCCCCCCCCCCCCC
EPAGEAAAQAVTFEAEGTVPADDLWGAFELEEEVAGEVEVGEMVPGDEAMGEVFDAAAFA
CCCHHHHHHEEEEECCCCCCHHHHCCCEEEHHHHCCCEEECCCCCCHHHHHHHHHHHHHH
AAPAASADSGTFGVPVEEFTFTEEPAFGTVEETISFGAVAEPESFAFEPEPTAGVQAAEA
HCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
FAAEPAAGFEFGGTAVPEQFVVEQQFAPDEEYVSAVPPAASTSVAPVVEPVAPGSGTITL
HHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCEEEE
TEEQLAAAISRISREVIERIAWEVVPELAETIIKEEIRKIKEGL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
GNRLLLADDSITIQKVVGIIFANEDFELTVVDNGDAALEKARESRPDVMLIDALMPGSN
CCEEEEECCCEEHHHHHHHEEECCCEEEEEEECCHHHHHHHHHCCCCEEEEEEECCCCC
GYEVCAAVRQDPALKNTPLLLMTGAFEPFDEDRARQCGADDFISKPFESQQLVDKVKELL
CHHHHHHHHCCCCCCCCCEEEEECCCCCCCHHHHHHCCCHHHHCCCCCHHHHHHHHHHHH
ALGGSRAVTGAGAAPDFAAEIPAAVFEVEPESFVSSPEPSAVFEPATPEPFPVFESEPLA
HCCCCCEECCCCCCCCHHHHCCHHHEEECHHHHHCCCCCCCEECCCCCCCCCCCCCCCCC
EPAGEAAAQAVTFEAEGTVPADDLWGAFELEEEVAGEVEVGEMVPGDEAMGEVFDAAAFA
CCCHHHHHHEEEEECCCCCCHHHHCCCEEEHHHHCCCEEECCCCCCHHHHHHHHHHHHHH
AAPAASADSGTFGVPVEEFTFTEEPAFGTVEETISFGAVAEPESFAFEPEPTAGVQAAEA
HCCCCCCCCCCCCCCHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHH
FAAEPAAGFEFGGTAVPEQFVVEQQFAPDEEYVSAVPPAASTSVAPVVEPVAPGSGTITL
HHCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHHCCCCCCCCCCCHHHCCCCCCCCEEEE
TEEQLAAAISRISREVIERIAWEVVPELAETIIKEEIRKIKEGL
EHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715; 8682783 [H]