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The map label for this gene is argS [H]

Identifier: 39996911

GI number: 39996911

Start: 1978284

End: 1979990

Strand: Reverse

Name: argS [H]

Synonym: GSU1812

Alternate gene names: 39996911

Gene position: 1979990-1978284 (Counterclockwise)

Preceding gene: 39996912

Following gene: 39996910

Centisome position: 51.91

GC content: 60.22

Gene sequence:

>1707_bases
ATGAGTCAGATAGAAGGTTCCATGAAAGATGCGGTCAGGGATCTGGTGCGCGAGGCGCTTGAGCGCTCTTTCGCGGACGG
CACCCTCGCCTCGGGCCACGTGCCCGATATTGTAGTTGAAAAGCCGGCCCTCGAAGAACACGGAGATTTCGCGTGCACCG
CAGCCATGCTGATGGCGAAGGCGGAAAAGAAGGCACCGCGGGCAATTGCCGAGATTATCATTACTCACCTGAACGATCGG
GAATCACTGGTCGAGTCGGTTGAAATTGCCGGCCCCGGTTTTATTAATTTCAGAATGCGCACCAGTGCCTGGTGTCGGGT
ACTTCGCAGAATCGAACGCGAAGGCGGGGACTACGGCAAAAGTGAGGCCGGCGCAGGGAAGAAAGTACAGGTGGAGTTCG
TCAGTGCCAATCCCACCGGGCCTCTGCATATCGGGCACGGTCGCGGCGCTGCCATCGGCGACACCATCTGTCGTCTTCTT
GCCGCAATCGGCTGGGATGTGACCCGCGAGTTCTACTACAACGATGCCGGTCAGCAGATCGCCAACCTGGCGCTGTCGGT
GCAGGCCCGCTGCCTCGGTGTTGAGCCGGGAGGTCCCTTGTGGCCCACGGACGGCTACCAGGGTGAGTATATAAAGGACG
TGGCCCGCTCCTATCTGAACCGCGAAACCGTTGATGCCGGCGACCAGCATGTAACAGCGGCCGGAGACCCCCACGACGTG
GAGGCGATCCGCCGCTTTGCCGTCGCATATCTGCGGCGGGAGCAGGACCAGGATCTGCGGGCATTCGACGTGGGATTCGA
CGTCTACTTCCTCGAGTCGAGCCTCTATGCCGAGGGACGGGTTGACGACGTGGTGCAGCGCATCATTGCCAAGGGCCATG
CCTACGAGCAGGACGGCGCTCTCTGGCTGAGGACCACCGAGTTCGGCGACGACAAGGACCGCGTCATGCGCAAGTCGGAC
GGCAGCTACACCTACTTCGTGCCTGACGTGGCCTACCACCTCAACAAGTGGGAACGGGGATTCATCCGGGTCGTCAACGA
GCAGGGGGCCGATCACCACAGCACCATCACCCGGGTGAGGGCCGGCCTCCAGGCCCTTGACGCGGGGATCCCCAAGGGAT
GGCCCGAGTACGTTCTCCACCAGATGGTCACGGTCATGCGTGGTGGCGAAGAGGTCAAGATCTCCAAACGGGCCGGAAGC
TATGTTACTCTGCGCGATCTCGTCGACGAGGTGGGTCGTGACGCCACGCGGTTCTTCTTTCTCATGCGCAAGCCCGATTC
CCAGTTGGTGTTCGATATCGATCTAGCCAAGCAGCAGACCCTCGAAAACCCCGTTTACTATGTGCAGTATGCCCATGCGC
GCATCTGCAGCATCTTCGAGAACGCGGCCGACAAGGGTGTTGTCCCGCCAACCGTTGATCAGGCCAGCCTGGAAAGCTTG
GGGACTCCCGAAGAGCTGACACTCGTGAAGCTGCTGAGTTCGTTCCCCGAGATCGTGGAAGGAAGTGCGCTTAATTTCGA
ACCCCACCGGATCACCTACTACTTGCAGGAACTTGCCGGTGCCTTCCACTCGTTCTATAACAAGAACCGGGTCATTACCG
AAGATGCAGACCTGACCGGTGCGCGCCTGCTTCTGCTGCACAGCACGGCAACCGTGATCAGAAACGGCCTCGGGCTACTG
GGTGTGTCTGCTCCCGAGAAGATGTAG

Upstream 100 bases:

>100_bases
CCAAAAAGTTTTGCGTCACTGATGGCGGAGCCCGTTGTCCCGACTTTTCGAGAGACGTCTCCATCAAGGACGTGGAAGAA
GAGCCCAATGAGGAGACGAA

Downstream 100 bases:

>100_bases
CGGAGCGCGGTCAGATGGTTCTGGATTATCGCGAACGAAAGACGGTCAGTAAGAACCGTCCCAAATCAAAGCCGATTGGG
CTCCTTGCGTGTGCCTTCCT

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 568; Mature: 567

Protein sequence:

>568_residues
MSQIEGSMKDAVRDLVREALERSFADGTLASGHVPDIVVEKPALEEHGDFACTAAMLMAKAEKKAPRAIAEIIITHLNDR
ESLVESVEIAGPGFINFRMRTSAWCRVLRRIEREGGDYGKSEAGAGKKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLL
AAIGWDVTREFYYNDAGQQIANLALSVQARCLGVEPGGPLWPTDGYQGEYIKDVARSYLNRETVDAGDQHVTAAGDPHDV
EAIRRFAVAYLRREQDQDLRAFDVGFDVYFLESSLYAEGRVDDVVQRIIAKGHAYEQDGALWLRTTEFGDDKDRVMRKSD
GSYTYFVPDVAYHLNKWERGFIRVVNEQGADHHSTITRVRAGLQALDAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGS
YVTLRDLVDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQTLENPVYYVQYAHARICSIFENAADKGVVPPTVDQASLESL
GTPEELTLVKLLSSFPEIVEGSALNFEPHRITYYLQELAGAFHSFYNKNRVITEDADLTGARLLLLHSTATVIRNGLGLL
GVSAPEKM

Sequences:

>Translated_568_residues
MSQIEGSMKDAVRDLVREALERSFADGTLASGHVPDIVVEKPALEEHGDFACTAAMLMAKAEKKAPRAIAEIIITHLNDR
ESLVESVEIAGPGFINFRMRTSAWCRVLRRIEREGGDYGKSEAGAGKKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLL
AAIGWDVTREFYYNDAGQQIANLALSVQARCLGVEPGGPLWPTDGYQGEYIKDVARSYLNRETVDAGDQHVTAAGDPHDV
EAIRRFAVAYLRREQDQDLRAFDVGFDVYFLESSLYAEGRVDDVVQRIIAKGHAYEQDGALWLRTTEFGDDKDRVMRKSD
GSYTYFVPDVAYHLNKWERGFIRVVNEQGADHHSTITRVRAGLQALDAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGS
YVTLRDLVDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQTLENPVYYVQYAHARICSIFENAADKGVVPPTVDQASLESL
GTPEELTLVKLLSSFPEIVEGSALNFEPHRITYYLQELAGAFHSFYNKNRVITEDADLTGARLLLLHSTATVIRNGLGLL
GVSAPEKM
>Mature_567_residues
SQIEGSMKDAVRDLVREALERSFADGTLASGHVPDIVVEKPALEEHGDFACTAAMLMAKAEKKAPRAIAEIIITHLNDRE
SLVESVEIAGPGFINFRMRTSAWCRVLRRIEREGGDYGKSEAGAGKKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLLA
AIGWDVTREFYYNDAGQQIANLALSVQARCLGVEPGGPLWPTDGYQGEYIKDVARSYLNRETVDAGDQHVTAAGDPHDVE
AIRRFAVAYLRREQDQDLRAFDVGFDVYFLESSLYAEGRVDDVVQRIIAKGHAYEQDGALWLRTTEFGDDKDRVMRKSDG
SYTYFVPDVAYHLNKWERGFIRVVNEQGADHHSTITRVRAGLQALDAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSY
VTLRDLVDEVGRDATRFFFLMRKPDSQLVFDIDLAKQQTLENPVYYVQYAHARICSIFENAADKGVVPPTVDQASLESLG
TPEELTLVKLLSSFPEIVEGSALNFEPHRITYYLQELAGAFHSFYNKNRVITEDADLTGARLLLLHSTATVIRNGLGLLG
VSAPEKM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=591, Percent_Identity=26.9035532994924, Blast_Score=133, Evalue=4e-31,
Organism=Escherichia coli, GI1788184, Length=576, Percent_Identity=25.8680555555556, Blast_Score=127, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI71985061, Length=624, Percent_Identity=25.6410256410256, Blast_Score=115, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71985068, Length=584, Percent_Identity=25.6849315068493, Blast_Score=110, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320548, Length=526, Percent_Identity=24.7148288973384, Blast_Score=118, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6321883, Length=501, Percent_Identity=23.5528942115768, Blast_Score=108, Evalue=2e-24,
Organism=Drosophila melanogaster, GI18859963, Length=573, Percent_Identity=26.1780104712042, Blast_Score=120, Evalue=2e-27,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 63042; Mature: 62911

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQIEGSMKDAVRDLVREALERSFADGTLASGHVPDIVVEKPALEEHGDFACTAAMLMAK
CCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHCCCHHHHHHHHHHH
AEKKAPRAIAEIIITHLNDRESLVESVEIAGPGFINFRMRTSAWCRVLRRIEREGGDYGK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCCCCC
SEAGAGKKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLLAAIGWDVTREFYYNDAGQQI
CCCCCCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCHHHHH
ANLALSVQARCLGVEPGGPLWPTDGYQGEYIKDVARSYLNRETVDAGDQHVTAAGDPHDV
HHHHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHH
EAIRRFAVAYLRREQDQDLRAFDVGFDVYFLESSLYAEGRVDDVVQRIIAKGHAYEQDGA
HHHHHHHHHHHHHCCCCCCEEEECCEEEEEEECHHCCCCCHHHHHHHHHHCCCCCCCCCE
LWLRTTEFGDDKDRVMRKSDGSYTYFVPDVAYHLNKWERGFIRVVNEQGADHHSTITRVR
EEEEECCCCCCHHHHHHCCCCCEEEECCHHHHHHCHHCCHHHEEECCCCCCHHHHHHHHH
AGLQALDAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLVDEVGRDATRFFF
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCEEEEE
LMRKPDSQLVFDIDLAKQQTLENPVYYVQYAHARICSIFENAADKGVVPPTVDQASLESL
EEECCCCCEEEEEEHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHC
GTPEELTLVKLLSSFPEIVEGSALNFEPHRITYYLQELAGAFHSFYNKNRVITEDADLTG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
ARLLLLHSTATVIRNGLGLLGVSAPEKM
CEEEEEHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure 
SQIEGSMKDAVRDLVREALERSFADGTLASGHVPDIVVEKPALEEHGDFACTAAMLMAK
CCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCHHCCCHHHHHHHHHHH
AEKKAPRAIAEIIITHLNDRESLVESVEIAGPGFINFRMRTSAWCRVLRRIEREGGDYGK
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEEEECHHHHHHHHHHHHHCCCCCCC
SEAGAGKKVQVEFVSANPTGPLHIGHGRGAAIGDTICRLLAAIGWDVTREFYYNDAGQQI
CCCCCCCEEEEEEEECCCCCCEEECCCCCCHHHHHHHHHHHHHCHHHHHHHHHCCHHHHH
ANLALSVQARCLGVEPGGPLWPTDGYQGEYIKDVARSYLNRETVDAGDQHVTAAGDPHDV
HHHHHHEEEEEEECCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEECCCCCHHH
EAIRRFAVAYLRREQDQDLRAFDVGFDVYFLESSLYAEGRVDDVVQRIIAKGHAYEQDGA
HHHHHHHHHHHHHCCCCCCEEEECCEEEEEEECHHCCCCCHHHHHHHHHHCCCCCCCCCE
LWLRTTEFGDDKDRVMRKSDGSYTYFVPDVAYHLNKWERGFIRVVNEQGADHHSTITRVR
EEEEECCCCCCHHHHHHCCCCCEEEECCHHHHHHCHHCCHHHEEECCCCCCHHHHHHHHH
AGLQALDAGIPKGWPEYVLHQMVTVMRGGEEVKISKRAGSYVTLRDLVDEVGRDATRFFF
HHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEHHHHHHHHCCCCEEEEE
LMRKPDSQLVFDIDLAKQQTLENPVYYVQYAHARICSIFENAADKGVVPPTVDQASLESL
EEECCCCCEEEEEEHHHHHHHCCCEEEEEHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHC
GTPEELTLVKLLSSFPEIVEGSALNFEPHRITYYLQELAGAFHSFYNKNRVITEDADLTG
CCCHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
ARLLLLHSTATVIRNGLGLLGVSAPEKM
CEEEEEHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA