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The map label for this gene is acpS

Identifier: 39996902

GI number: 39996902

Start: 1969157

End: 1969537

Strand: Reverse

Name: acpS

Synonym: GSU1803

Alternate gene names: 39996902

Gene position: 1969537-1969157 (Counterclockwise)

Preceding gene: 39996903

Following gene: 39996901

Centisome position: 51.64

GC content: 59.84

Gene sequence:

>381_bases
ATGATTTTCGGTACCGGCATCGATATCGTCGACATTACCCGTTTCGACCGCCTGGTCGAAGAAGGGAACGTGCGTCTCTT
CGAGCGGCTCTTTACGCCTCATGAAATGGAGTACTGTGCCGGCAAGGCCCGGAGCTCCCAGCACTATGCCCTGCGGTTCG
CGGCCAAGGAGGCGTTTCTCAAGGCCTGCGGTCTCGGCCTGCGTGAAGGGATGACCTGGCATGACGTGGAGGTCGTCAAT
GATACTCTCGGTAAGCCCGAGCTCAAGCTCCACGGCAAAGCCCTGAAGCTGGCCACCGACCTGAGCCTCAGTCGGACTTT
CGTTTCCCTTTCCCACGACGGAGCATACGCCGTCGCCCTAGTTGTGCTGGAGCGCCCATGA

Upstream 100 bases:

>100_bases
GTATCGAGGAATTCAACATCGGACATTCCATAATCTCACGCGCAGTGTTTACCGGGCTCGACCGTGCCGTGCGGGACATG
GTAGACCTCGTCAAGTACGC

Downstream 100 bases:

>100_bases
AGGTGGTGAGCGGCGAAACCATGCAGCGGATGGACCGTCGCGCCATCGACGAGTTCGGTATCCCCGGCCTTGTCCTCATG
GAAAACGCCGGCCGCGGATG

Product: 4'-phosphopantetheinyl transferase

Products: NA

Alternate protein names: Holo-ACP synthase; 4'-phosphopantetheinyl transferase AcpS

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MIFGTGIDIVDITRFDRLVEEGNVRLFERLFTPHEMEYCAGKARSSQHYALRFAAKEAFLKACGLGLREGMTWHDVEVVN
DTLGKPELKLHGKALKLATDLSLSRTFVSLSHDGAYAVALVVLERP

Sequences:

>Translated_126_residues
MIFGTGIDIVDITRFDRLVEEGNVRLFERLFTPHEMEYCAGKARSSQHYALRFAAKEAFLKACGLGLREGMTWHDVEVVN
DTLGKPELKLHGKALKLATDLSLSRTFVSLSHDGAYAVALVVLERP
>Mature_126_residues
MIFGTGIDIVDITRFDRLVEEGNVRLFERLFTPHEMEYCAGKARSSQHYALRFAAKEAFLKACGLGLREGMTWHDVEVVN
DTLGKPELKLHGKALKLATDLSLSRTFVSLSHDGAYAVALVVLERP

Specific function: Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein

COG id: COG0736

COG function: function code I; Phosphopantetheinyl transferase (holo-ACP synthase)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the P-Pant transferase superfamily. AcpS family

Homologues:

Organism=Escherichia coli, GI1788916, Length=123, Percent_Identity=39.8373983739837, Blast_Score=89, Evalue=8e-20,
Organism=Saccharomyces cerevisiae, GI6325025, Length=120, Percent_Identity=37.5, Blast_Score=72, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACPS_GEOSL (Q74C71)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952853.1
- ProteinModelPortal:   Q74C71
- SMR:   Q74C71
- GeneID:   2687421
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1803
- NMPDR:   fig|243231.1.peg.1791
- TIGR:   GSU1803
- HOGENOM:   HBG734479
- OMA:   QGVFWRD
- ProtClustDB:   PRK14656
- BioCyc:   GSUL243231:GSU_1803-MONOMER
- BRENDA:   2.7.8.7
- GO:   GO:0005737
- HAMAP:   MF_00101
- InterPro:   IPR008278
- InterPro:   IPR002582
- InterPro:   IPR004568
- ProDom:   PD004282
- TIGRFAMs:   TIGR00516
- TIGRFAMs:   TIGR00556

Pfam domain/function: PF01648 ACPS; SSF56214 4-PPT_transf

EC number: =2.7.8.7

Molecular weight: Translated: 14078; Mature: 14078

Theoretical pI: Translated: 7.06; Mature: 7.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIFGTGIDIVDITRFDRLVEEGNVRLFERLFTPHEMEYCAGKARSSQHYALRFAAKEAFL
CEECCCCCEEEHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCCHHEEHHHHHHHHH
KACGLGLREGMTWHDVEVVNDTLGKPELKLHGKALKLATDLSLSRTFVSLSHDGAYAVAL
HHHCCHHHCCCCCCHHHHHHHCCCCCCEEECCCEEEEECCCCHHHEEEEECCCCCEEEEE
VVLERP
EEEECC
>Mature Secondary Structure
MIFGTGIDIVDITRFDRLVEEGNVRLFERLFTPHEMEYCAGKARSSQHYALRFAAKEAFL
CEECCCCCEEEHHHHHHHHHCCCHHHHHHHCCCCHHHHHHCCCCCCCHHEEHHHHHHHHH
KACGLGLREGMTWHDVEVVNDTLGKPELKLHGKALKLATDLSLSRTFVSLSHDGAYAVAL
HHHCCHHHCCCCCCHHHHHHHCCCCCCEEECCCEEEEECCCCHHHEEEEECCCCCEEEEE
VVLERP
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA