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The map label for this gene is glcK [H]

Identifier: 39996802

GI number: 39996802

Start: 1864395

End: 1865351

Strand: Direct

Name: glcK [H]

Synonym: GSU1702

Alternate gene names: 39996802

Gene position: 1864395-1865351 (Clockwise)

Preceding gene: 39996801

Following gene: 39996803

Centisome position: 48.88

GC content: 61.76

Gene sequence:

>957_bases
ATGATCCGCCCGGCGTTCATCGGCATGGATATCGGTGGGACCAATCTGCGGATGGGACTCGTCGACGAGGCGGGAACGAT
CCTTTTCCGCTTCAGGCAGAAAACCGATATTCATGAGGGGAGAGCCGCCTTTTACGAAAAGCTCGCCGAGGGGATAGGCA
TTCTCAAAGAGCACGCAGAGCAGGCGGGATTCCGCATCGTGGCAGTTGGTGCCGGCGTTCCGGGGCTTGTGGCAAATGAC
GGACATATCCACGTATCGGTGAATCTTCCGGCCATTGACAGCATCAACCTCCGCCATGACCTGGAACGCATCAGTGGTCT
GCCGGCGACGGTGGCCAACGATGTCAACGCCACCGCGTACGGCGAGAAATCCTTCGGTGCCGGACGCGAGTTCGACTCGT
TCCTGATGGTTACACTCGGCACCGGCGTCGGAGGAGGGCTCATCCTGAACGGGCGGCTGTGGACCGGAATCGACGGCGTA
GCCGGCGAGTTCGGTCATGTGACGGTCGAGCCCCAGGGGACGTCCTGTCCCTGCGGCAACCGGGGTTGTCTTGAGCAATA
TGCCTCTGCCACGGCCATAGCCTCAGCCGCGCGAGAGGCCATGATGACGGGGCGATACGTACCGGCTGACGGGTCTGCGA
TACCTCTCACTACCCAGGATCTGGCCCGTCTCGCCCGGGAAGGGGATGGTGCGGCGGCGACATTTTTCGCCGAGGCGGGA
CGTTATCTGGGCATGGCAACGGCATCACTGGCCAACGTACTCAATCTGGAAGCACTGATCGTTGGTGGGGGCGTCGCTGC
AAGCTTTGATCTGATCAGGAGTTCCATAGAGCGAGAGGTTCGTGCCCGAGCTTTCCCGATTCCGGCCCAGCGGCTGGTGG
TGGTCCGTGGCGCATTGGGCGACGACGGAGGACTCCTGGGAAGCGCTGCGCTGGCCCGTGATGAGTTCGACATCTAA

Upstream 100 bases:

>100_bases
ACACGAATTTCATGGGGGTCGTGGCGGATCTACGGGTAGTGCCGGAAGGGCTTCAGGCTGCCTGGGACCGCCTGGCCCCG
CTGTTCTCACGGGAGACCCC

Downstream 100 bases:

>100_bases
GAGAGTAGAGAGTATTTTCATAGTTATCAACGACGGGGAGGAATCATGGCGCGTAAAGTAGGCATACTGACCGGGGGGGG
AGACTGCCCGGGACTCAATG

Product: ROK family protein

Products: NA

Alternate protein names: Glucose kinase [H]

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MIRPAFIGMDIGGTNLRMGLVDEAGTILFRFRQKTDIHEGRAAFYEKLAEGIGILKEHAEQAGFRIVAVGAGVPGLVAND
GHIHVSVNLPAIDSINLRHDLERISGLPATVANDVNATAYGEKSFGAGREFDSFLMVTLGTGVGGGLILNGRLWTGIDGV
AGEFGHVTVEPQGTSCPCGNRGCLEQYASATAIASAAREAMMTGRYVPADGSAIPLTTQDLARLAREGDGAAATFFAEAG
RYLGMATASLANVLNLEALIVGGGVAASFDLIRSSIEREVRARAFPIPAQRLVVVRGALGDDGGLLGSAALARDEFDI

Sequences:

>Translated_318_residues
MIRPAFIGMDIGGTNLRMGLVDEAGTILFRFRQKTDIHEGRAAFYEKLAEGIGILKEHAEQAGFRIVAVGAGVPGLVAND
GHIHVSVNLPAIDSINLRHDLERISGLPATVANDVNATAYGEKSFGAGREFDSFLMVTLGTGVGGGLILNGRLWTGIDGV
AGEFGHVTVEPQGTSCPCGNRGCLEQYASATAIASAAREAMMTGRYVPADGSAIPLTTQDLARLAREGDGAAATFFAEAG
RYLGMATASLANVLNLEALIVGGGVAASFDLIRSSIEREVRARAFPIPAQRLVVVRGALGDDGGLLGSAALARDEFDI
>Mature_318_residues
MIRPAFIGMDIGGTNLRMGLVDEAGTILFRFRQKTDIHEGRAAFYEKLAEGIGILKEHAEQAGFRIVAVGAGVPGLVAND
GHIHVSVNLPAIDSINLRHDLERISGLPATVANDVNATAYGEKSFGAGREFDSFLMVTLGTGVGGGLILNGRLWTGIDGV
AGEFGHVTVEPQGTSCPCGNRGCLEQYASATAIASAAREAMMTGRYVPADGSAIPLTTQDLARLAREGDGAAATFFAEAG
RYLGMATASLANVLNLEALIVGGGVAASFDLIRSSIEREVRARAFPIPAQRLVVVRGALGDDGGLLGSAALARDEFDI

Specific function: Acts As A Repressor Of The Nagebacd Operon And Acts Both As An Activator And A Repressor For The Transcription Of The Glmsu Operon. [C]

COG id: COG1940

COG function: function code KG; Transcriptional regulator/sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ROK (nagC/xylR) family [H]

Homologues:

Organism=Homo sapiens, GI298566315, Length=284, Percent_Identity=29.5774647887324, Blast_Score=99, Evalue=5e-21,
Organism=Homo sapiens, GI298566325, Length=284, Percent_Identity=29.5774647887324, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI4885285, Length=284, Percent_Identity=29.5774647887324, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI190014632, Length=284, Percent_Identity=29.5774647887324, Blast_Score=98, Evalue=8e-21,
Organism=Escherichia coli, GI1786891, Length=253, Percent_Identity=31.6205533596838, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1787878, Length=251, Percent_Identity=27.8884462151394, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787363, Length=319, Percent_Identity=27.5862068965517, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI87081733, Length=318, Percent_Identity=27.0440251572327, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790522, Length=317, Percent_Identity=28.7066246056782, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI87082127, Length=178, Percent_Identity=26.4044943820225, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI87082230, Length=262, Percent_Identity=30.1526717557252, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000600
- InterPro:   IPR004654 [H]

Pfam domain/function: PF00480 ROK [H]

EC number: =2.7.1.2 [H]

Molecular weight: Translated: 33096; Mature: 33096

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS01125 ROK

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRPAFIGMDIGGTNLRMGLVDEAGTILFRFRQKTDIHEGRAAFYEKLAEGIGILKEHAE
CCCCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QAGFRIVAVGAGVPGLVANDGHIHVSVNLPAIDSINLRHDLERISGLPATVANDVNATAY
HCCEEEEEECCCCCCEEECCCEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHCCCCCEEC
GEKSFGAGREFDSFLMVTLGTGVGGGLILNGRLWTGIDGVAGEFGHVTVEPQGTSCPCGN
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEECCCCCCCCCCC
RGCLEQYASATAIASAAREAMMTGRYVPADGSAIPLTTQDLARLAREGDGAAATFFAEAG
CHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHCC
RYLGMATASLANVLNLEALIVGGGVAASFDLIRSSIEREVRARAFPIPAQRLVVVRGALG
HHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCC
DDGGLLGSAALARDEFDI
CCCCCHHHHHHCCCCCCC
>Mature Secondary Structure
MIRPAFIGMDIGGTNLRMGLVDEAGTILFRFRQKTDIHEGRAAFYEKLAEGIGILKEHAE
CCCCEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHH
QAGFRIVAVGAGVPGLVANDGHIHVSVNLPAIDSINLRHDLERISGLPATVANDVNATAY
HCCEEEEEECCCCCCEEECCCEEEEEEECCCCCCCCHHHHHHHHCCCCCHHHCCCCCEEC
GEKSFGAGREFDSFLMVTLGTGVGGGLILNGRLWTGIDGVAGEFGHVTVEPQGTSCPCGN
CCCCCCCCCCCCCEEEEEECCCCCCCEEECCEEEECCCCCCCCCCEEEECCCCCCCCCCC
RGCLEQYASATAIASAAREAMMTGRYVPADGSAIPLTTQDLARLAREGDGAAATFFAEAG
CHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCCCHHHHHHHHHCCCCCEEHHHHHCC
RYLGMATASLANVLNLEALIVGGGVAASFDLIRSSIEREVRARAFPIPAQRLVVVRGALG
HHHHHHHHHHHHHHCEEEEEECCCHHHHHHHHHHHHHHHHHHHCCCCCHHEEEEEEECCC
DDGGLLGSAALARDEFDI
CCCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]