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The map label for this gene is fbP-1

Identifier: 39996751

GI number: 39996751

Start: 1809102

End: 1810043

Strand: Direct

Name: fbP-1

Synonym: GSU1651

Alternate gene names: 39996751

Gene position: 1809102-1810043 (Clockwise)

Preceding gene: 39996744

Following gene: 39996752

Centisome position: 47.43

GC content: 56.48

Gene sequence:

>942_bases
ATGCCGTTCAGCGAGCCGGGCAAGACGAAATTCCAGGTAGACCTACGCCGTCATCTGCGAAATCAGGATATCAGCGATAA
CCTCGTGCACCTGATCTGCGAGATTGCCGAGGCAAGCAAGTATGTGATCAACGCAGTCCGCACCGGTGATCTCGGCGTGG
CCGGTACCTCGAACCTCTACGGTGAGGAGCAGTTGGCCCTGGACGTGCTTTCGGACCGGATCATCAGAAAACGGCTCATC
CATTCAGGAGTTGTCTGCAACATTGCATCCGAGGAGATGGATGAGATCTTCCAGGCCCAGGCCGACGCCGACGGTCTCTA
CTCGGTGGCGTACGATCCCCTCGACGGCTCGTCGCTCGTTGATGTGAATCTTGCCGTGGGAACCATCGTGTCGATTTACG
AAGGGTGCAACCTGCTCCAGAAGGGGCGTAATCAGGTGGCAGCCATGTACATACTCTACGGCCCCCGTGTTTCGCTGGTG
TATTCCGTGGGCAAAGGCGTTCACGAGTTCACCATGAACCATCTCATGGAGTACACCCTGAGCCGGGAGAACGTCACCAT
GAAGCCGGACGGAGACATCTACTCCCCTGGCGGACTGCGCAAAAAGTACCTGCCGGAAACGGAAAAATTCGTGCAGCACC
TTGAGAGTAAGGGATCCAAGCTTCGCTATTCGGGCGGCTTTGTGCCCGACATCAACCAGGTACTGATGAAAGGGAAGGGT
ATTTTCATGTATCCTGCCCTCAACGGTTCACCTAACGGCAAACTGCGCGTACTTTTCGAGCTGAACCCCATGGCTTACCT
CATCGAAAATGCAGGAGGGGCGGCCACTGACGGCAAGACGCCCATCCTCGACATCGAGCCGCAATCTCTCGACCAGCGGG
CTCCCATTTTCATTGGTTGCTCCAATGACGTAGCCACGGCCATGGAGTTCATGGGCGGCTGA

Upstream 100 bases:

>100_bases
GCGGCATGGGCTGCAGAGGTTACATTTCGCTTGATTCTACGCCATGTTTACATGTAATCTTTGAGCGTTTTCACCTATCC
GATACTTCAGGAGGATGCGA

Downstream 100 bases:

>100_bases
TTCATGCCGCAGTTTCAACCAAGAGGGGGATGATCATGGAAGAGAGCCAAAAGCAGCCAAGACTCTGTTCGGAGATCCAG
CTGTTCGATCTCTGCGAAGT

Product: fructose-1,6-bisphosphatase

Products: NA

Alternate protein names: FBPase class 1; D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MPFSEPGKTKFQVDLRRHLRNQDISDNLVHLICEIAEASKYVINAVRTGDLGVAGTSNLYGEEQLALDVLSDRIIRKRLI
HSGVVCNIASEEMDEIFQAQADADGLYSVAYDPLDGSSLVDVNLAVGTIVSIYEGCNLLQKGRNQVAAMYILYGPRVSLV
YSVGKGVHEFTMNHLMEYTLSRENVTMKPDGDIYSPGGLRKKYLPETEKFVQHLESKGSKLRYSGGFVPDINQVLMKGKG
IFMYPALNGSPNGKLRVLFELNPMAYLIENAGGAATDGKTPILDIEPQSLDQRAPIFIGCSNDVATAMEFMGG

Sequences:

>Translated_313_residues
MPFSEPGKTKFQVDLRRHLRNQDISDNLVHLICEIAEASKYVINAVRTGDLGVAGTSNLYGEEQLALDVLSDRIIRKRLI
HSGVVCNIASEEMDEIFQAQADADGLYSVAYDPLDGSSLVDVNLAVGTIVSIYEGCNLLQKGRNQVAAMYILYGPRVSLV
YSVGKGVHEFTMNHLMEYTLSRENVTMKPDGDIYSPGGLRKKYLPETEKFVQHLESKGSKLRYSGGFVPDINQVLMKGKG
IFMYPALNGSPNGKLRVLFELNPMAYLIENAGGAATDGKTPILDIEPQSLDQRAPIFIGCSNDVATAMEFMGG
>Mature_312_residues
PFSEPGKTKFQVDLRRHLRNQDISDNLVHLICEIAEASKYVINAVRTGDLGVAGTSNLYGEEQLALDVLSDRIIRKRLIH
SGVVCNIASEEMDEIFQAQADADGLYSVAYDPLDGSSLVDVNLAVGTIVSIYEGCNLLQKGRNQVAAMYILYGPRVSLVY
SVGKGVHEFTMNHLMEYTLSRENVTMKPDGDIYSPGGLRKKYLPETEKFVQHLESKGSKLRYSGGFVPDINQVLMKGKGI
FMYPALNGSPNGKLRVLFELNPMAYLIENAGGAATDGKTPILDIEPQSLDQRAPIFIGCSNDVATAMEFMGG

Specific function: INVOLVED IN SEVERAL METABOLIC PATHWAYS. IN E.COLI AND YEAST IT IS NECESSARY FOR GROWTH ON SUBSTANCES SUCH AS GLYCEROL, SUCCINATE AND ACETATE. [C]

COG id: COG0158

COG function: function code G; Fructose-1,6-bisphosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FBPase class 1 family

Homologues:

Organism=Homo sapiens, GI189083692, Length=322, Percent_Identity=37.2670807453416, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI16579888, Length=322, Percent_Identity=37.2670807453416, Blast_Score=175, Evalue=4e-44,
Organism=Homo sapiens, GI22907028, Length=323, Percent_Identity=37.4613003095975, Blast_Score=174, Evalue=8e-44,
Organism=Escherichia coli, GI1790679, Length=284, Percent_Identity=40.4929577464789, Blast_Score=183, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17508131, Length=320, Percent_Identity=38.4375, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6323409, Length=325, Percent_Identity=32.6153846153846, Blast_Score=163, Evalue=4e-41,
Organism=Drosophila melanogaster, GI45550998, Length=324, Percent_Identity=35.8024691358025, Blast_Score=169, Evalue=2e-42,
Organism=Drosophila melanogaster, GI19921562, Length=324, Percent_Identity=35.8024691358025, Blast_Score=169, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): F16PA_GEOSL (Q74CM2)

Other databases:

- EMBL:   AE017180
- RefSeq:   NP_952702.1
- HSSP:   P00636
- ProteinModelPortal:   Q74CM2
- GeneID:   2687220
- GenomeReviews:   AE017180_GR
- KEGG:   gsu:GSU1651
- NMPDR:   fig|243231.1.peg.1640
- TIGR:   GSU1651
- HOGENOM:   HBG731261
- OMA:   HWEAPVQ
- ProtClustDB:   PRK09293
- BioCyc:   GSUL243231:GSU_1651-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01855
- InterPro:   IPR000146
- InterPro:   IPR020548
- InterPro:   IPR023079
- PANTHER:   PTHR11556
- PRINTS:   PR01958

Pfam domain/function: PF00316 FBPase

EC number: =3.1.3.11

Molecular weight: Translated: 34334; Mature: 34203

Theoretical pI: Translated: 5.21; Mature: 5.21

Prosite motif: PS00124 FBPASE

Important sites: BINDING 223-223 BINDING 254-254

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFSEPGKTKFQVDLRRHLRNQDISDNLVHLICEIAEASKYVINAVRTGDLGVAGTSNLY
CCCCCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCC
GEEQLALDVLSDRIIRKRLIHSGVVCNIASEEMDEIFQAQADADGLYSVAYDPLDGSSLV
CCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCEE
DVNLAVGTIVSIYEGCNLLQKGRNQVAAMYILYGPRVSLVYSVGKGVHEFTMNHLMEYTL
EEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEHHCCCHHHHHHHHHHHHHH
SRENVTMKPDGDIYSPGGLRKKYLPETEKFVQHLESKGSKLRYSGGFVPDINQVLMKGKG
CCCCEEECCCCCEECCCCCCHHCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCC
IFMYPALNGSPNGKLRVLFELNPMAYLIENAGGAATDGKTPILDIEPQSLDQRAPIFIGC
EEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCEEEEC
SNDVATAMEFMGG
CCHHHHHHHHHCC
>Mature Secondary Structure 
PFSEPGKTKFQVDLRRHLRNQDISDNLVHLICEIAEASKYVINAVRTGDLGVAGTSNLY
CCCCCCCCEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCC
GEEQLALDVLSDRIIRKRLIHSGVVCNIASEEMDEIFQAQADADGLYSVAYDPLDGSSLV
CCHHHHHHHHHHHHHHHHHHHCCEEEEECHHHHHHHHHHHCCCCCEEEEEECCCCCCCEE
DVNLAVGTIVSIYEGCNLLQKGRNQVAAMYILYGPRVSLVYSVGKGVHEFTMNHLMEYTL
EEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEEHHCCCHHHHHHHHHHHHHH
SRENVTMKPDGDIYSPGGLRKKYLPETEKFVQHLESKGSKLRYSGGFVPDINQVLMKGKG
CCCCEEECCCCCEECCCCCCHHCCCCHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCC
IFMYPALNGSPNGKLRVLFELNPMAYLIENAGGAATDGKTPILDIEPQSLDQRAPIFIGC
EEEEECCCCCCCCCEEEEEEECCCEEEEECCCCCCCCCCCCEEECCCCCCCCCCCEEEEC
SNDVATAMEFMGG
CCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA