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The map label for this gene is lutB [H]

Identifier: 39996720

GI number: 39996720

Start: 1773123

End: 1775249

Strand: Reverse

Name: lutB [H]

Synonym: GSU1620

Alternate gene names: 39996720

Gene position: 1775249-1773123 (Counterclockwise)

Preceding gene: 39996721

Following gene: 39996719

Centisome position: 46.54

GC content: 59.61

Gene sequence:

>2127_bases
ATGGCACGGGACGTTATCAGGCAAAAAATCAACGACGCATTTCTGCGCAAAGCTCTTAAGAATTTTGCCGCAGCCTATCC
GGTGGCACGGGCCAAGGCCTTTGAAGGGGTTGATTTCGAGGCGCTTCGGTCAAGGATAGCGGCCTTCAAAAAGGAGGGCC
TTGCACGGTTGCCGGAGATGGTGAAGGAATTTACCGCCAGCGCCGAGCGGTCAGGGGCAACGGTTCATCTCTGCGCCACC
CCCGAAGAGGCGAACCGGACCATCCTGGAGATCATCCGCAAGGCCGGCGTAAACTTCCTCGTAAAATCAAAAGCCATGAC
CTCCGAGGAGATCGAGCTGAATCACTACCTGGGAAACAACGGGGTAACCTGCCTGGAAACCGATCTGGGCGAGTGGATCA
TCCAGCTGGCCGGCGAACGCCCCTCCCACATGGTCATGCCCGCCATCCACAAAAACCGGGAGGATGTGGCGGAACTCTTC
AGCCGGGAAACCGGCCTGGACTGCCCACCGGACATCCCACACTTGGTCAGGGTTGCCCGGGAAACGCTGCGCGATGGCTT
CCTCACCGGCCAGGTCGGACTGTCGGGAGCCAATGTGGCGATGGCCGATTCGGGTGCCATCGGCATAGTCACCAATGAAG
GGAACGGCCGACTCGTGACAACCCTTCCCCGTATCCACATCGCCCTGGTGGGGGTAGACAAGATCGTTCCCACCCTTTCC
GAAGCCCTGGACGTGATCACCATCCTCCCCAAGAACGCCACAGGACAGAAGATCACCTCCTATGTATCCTTCATCAAAGG
CCCCACGGGCGAAGGGCGGGAACTCCACATCGTGCTGCTCGACAACGGTCGGACCCGGCTGGCGGCCGATCCGGACTTTT
CTGAAGCCCTGGCCTGTGTCAAATGTGGTGCCTGCGCCAATGTCTGCCCTATTTACGAAATCGTGGGCGGCCACGTGTTC
GGCCATATCTACGTAGGGGGGATCGGGCTGGTGCTGACCCCCTTCTTCCACGGTCTCGACAAGGCCGAAGACATCCTCAA
GCTCTGCATTGGCTGTCGCAAGTGCAACGAAGTCTGCGCGGCAAAGATCGATATCGAAGGGCTCATCGTGGATCTGCGGG
ATAAGATCCGAAAGCCCGCCGGGCAAAAATTCCTCTTCGGCACCCTCATGAAAAACCGCGCACTCTTTCATGCAACCCTG
CGCACCGCATATCTGGCACAAAAACCGTTCCAGAGCGAAGGGGGGCGCATCCGGCACCTGCCGCTCATTCTCAACCGCGA
AACAGCCAACCGCTCCCTTCCCCCCATTGCCGAGAAACCGTTCCGCGACCTGATCGCGGAACAGCCGGGAACGAAGAAAC
AGGGCGCGGCGTCACGGGAAACAGTGCTATTTTATTCCGGCTGCCTGGCCGATTTCGTCTACCCCGAGATGTGCCTGGAT
ACCGTCAAGAGCCTGGAAGCCCTCGGTTATGAAGTCTCGTTCCCTCAGAAGCAGAGCTGTTGCGGCATACCGGCCCGCTA
TTCAGGAGAGATGGGCGTTGCCCGGGACCTGGCCAAAATCAACATCGATGTATTGCTGGAGGAGGATGCGGACTACGTGG
TCACCATCTGTCCCACCTGCACCATGTCATTGCGGCATGACTTTCCCAAGCTTTTGTCGACCGAGCCCCCATGGCGGGAA
AAGGCGGAGCGCTTGGCGGCCAAGACCTTCAACTTCTCCGAACTGGCCGCGCGGAAGGCGGGCTCCGGAATCCCCACGCA
CGAAACCGTGAACGGTGGAAAAGAGACCGTTACCTACCATGACGCCTGCCACCTCAAGCGGGGGTGCGGGGTACACGAGG
AACCGCGCAGAGTGCTCAGAGAGCTTGTCGGCGTGGAGATCGCCGAGATGACCGACTGCGACAAGTGCTGTGGCTTCGGC
GGTTCCTATTCCATCAAGTACCCCGAGATTTCCCAGGAGGTCTTGAAAAACAAGATGGAGACCATCAGGGAAACCGGTGC
GCGCACCGTGGCCGTGGACTGCCCCGGCTGCAAACTTCAGATCGAAGGGGGGCTGGAAGCCGCCGGAACCGGCATTGCCG
TAGAGCACTCCGCCACCCTCCTGGCGAGACGTCTCGTAACCCCTTAA

Upstream 100 bases:

>100_bases
AACCGGCCCGAGCCGCACTGCCGACATCGAGCGGGTTCTTACCATCGGCGTGCACGGCCCCAGGGAGCTCCACCTCCTGA
TCATCGAAGGAGAATAGGTA

Downstream 100 bases:

>100_bases
ATTAAACAGACATAATCTCGCCGTCCCCCGCCAAAAACAGCCGGAGCCCGTCTCCGGCTGTTTTTTTGCTAAACGAAACG
GGCAACCTGCCGATATGAAA

Product: iron-sulfur cluster binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 708; Mature: 707

Protein sequence:

>708_residues
MARDVIRQKINDAFLRKALKNFAAAYPVARAKAFEGVDFEALRSRIAAFKKEGLARLPEMVKEFTASAERSGATVHLCAT
PEEANRTILEIIRKAGVNFLVKSKAMTSEEIELNHYLGNNGVTCLETDLGEWIIQLAGERPSHMVMPAIHKNREDVAELF
SRETGLDCPPDIPHLVRVARETLRDGFLTGQVGLSGANVAMADSGAIGIVTNEGNGRLVTTLPRIHIALVGVDKIVPTLS
EALDVITILPKNATGQKITSYVSFIKGPTGEGRELHIVLLDNGRTRLAADPDFSEALACVKCGACANVCPIYEIVGGHVF
GHIYVGGIGLVLTPFFHGLDKAEDILKLCIGCRKCNEVCAAKIDIEGLIVDLRDKIRKPAGQKFLFGTLMKNRALFHATL
RTAYLAQKPFQSEGGRIRHLPLILNRETANRSLPPIAEKPFRDLIAEQPGTKKQGAASRETVLFYSGCLADFVYPEMCLD
TVKSLEALGYEVSFPQKQSCCGIPARYSGEMGVARDLAKINIDVLLEEDADYVVTICPTCTMSLRHDFPKLLSTEPPWRE
KAERLAAKTFNFSELAARKAGSGIPTHETVNGGKETVTYHDACHLKRGCGVHEEPRRVLRELVGVEIAEMTDCDKCCGFG
GSYSIKYPEISQEVLKNKMETIRETGARTVAVDCPGCKLQIEGGLEAAGTGIAVEHSATLLARRLVTP

Sequences:

>Translated_708_residues
MARDVIRQKINDAFLRKALKNFAAAYPVARAKAFEGVDFEALRSRIAAFKKEGLARLPEMVKEFTASAERSGATVHLCAT
PEEANRTILEIIRKAGVNFLVKSKAMTSEEIELNHYLGNNGVTCLETDLGEWIIQLAGERPSHMVMPAIHKNREDVAELF
SRETGLDCPPDIPHLVRVARETLRDGFLTGQVGLSGANVAMADSGAIGIVTNEGNGRLVTTLPRIHIALVGVDKIVPTLS
EALDVITILPKNATGQKITSYVSFIKGPTGEGRELHIVLLDNGRTRLAADPDFSEALACVKCGACANVCPIYEIVGGHVF
GHIYVGGIGLVLTPFFHGLDKAEDILKLCIGCRKCNEVCAAKIDIEGLIVDLRDKIRKPAGQKFLFGTLMKNRALFHATL
RTAYLAQKPFQSEGGRIRHLPLILNRETANRSLPPIAEKPFRDLIAEQPGTKKQGAASRETVLFYSGCLADFVYPEMCLD
TVKSLEALGYEVSFPQKQSCCGIPARYSGEMGVARDLAKINIDVLLEEDADYVVTICPTCTMSLRHDFPKLLSTEPPWRE
KAERLAAKTFNFSELAARKAGSGIPTHETVNGGKETVTYHDACHLKRGCGVHEEPRRVLRELVGVEIAEMTDCDKCCGFG
GSYSIKYPEISQEVLKNKMETIRETGARTVAVDCPGCKLQIEGGLEAAGTGIAVEHSATLLARRLVTP
>Mature_707_residues
ARDVIRQKINDAFLRKALKNFAAAYPVARAKAFEGVDFEALRSRIAAFKKEGLARLPEMVKEFTASAERSGATVHLCATP
EEANRTILEIIRKAGVNFLVKSKAMTSEEIELNHYLGNNGVTCLETDLGEWIIQLAGERPSHMVMPAIHKNREDVAELFS
RETGLDCPPDIPHLVRVARETLRDGFLTGQVGLSGANVAMADSGAIGIVTNEGNGRLVTTLPRIHIALVGVDKIVPTLSE
ALDVITILPKNATGQKITSYVSFIKGPTGEGRELHIVLLDNGRTRLAADPDFSEALACVKCGACANVCPIYEIVGGHVFG
HIYVGGIGLVLTPFFHGLDKAEDILKLCIGCRKCNEVCAAKIDIEGLIVDLRDKIRKPAGQKFLFGTLMKNRALFHATLR
TAYLAQKPFQSEGGRIRHLPLILNRETANRSLPPIAEKPFRDLIAEQPGTKKQGAASRETVLFYSGCLADFVYPEMCLDT
VKSLEALGYEVSFPQKQSCCGIPARYSGEMGVARDLAKINIDVLLEEDADYVVTICPTCTMSLRHDFPKLLSTEPPWREK
AERLAAKTFNFSELAARKAGSGIPTHETVNGGKETVTYHDACHLKRGCGVHEEPRRVLRELVGVEIAEMTDCDKCCGFGG
SYSIKYPEISQEVLKNKMETIRETGARTVAVDCPGCKLQIEGGLEAAGTGIAVEHSATLLARRLVTP

Specific function: Is involved in L-lactate degradation and allows cells to grow with lactate as the sole carbon source. Has probably a role as an electron transporter during oxidation of L-lactate [H]

COG id: COG1139

COG function: function code C; Uncharacterized conserved protein containing a ferredoxin-like domain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 4Fe-4S ferredoxin-type domains [H]

Homologues:

Organism=Escherichia coli, GI1786498, Length=374, Percent_Identity=36.8983957219251, Blast_Score=281, Evalue=9e-77,
Organism=Escherichia coli, GI1786497, Length=244, Percent_Identity=33.1967213114754, Blast_Score=136, Evalue=5e-33,
Organism=Escherichia coli, GI1788576, Length=419, Percent_Identity=27.6849642004773, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI48994913, Length=400, Percent_Identity=24, Blast_Score=96, Evalue=6e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017900
- InterPro:   IPR003741
- InterPro:   IPR004452
- InterPro:   IPR002698
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR022825 [H]

Pfam domain/function: PF02589 DUF162 [H]

EC number: NA

Molecular weight: Translated: 77207; Mature: 77076

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS00028 ZINC_FINGER_C2H2_1 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARDVIRQKINDAFLRKALKNFAAAYPVARAKAFEGVDFEALRSRIAAFKKEGLARLPEM
CCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VKEFTASAERSGATVHLCATPEEANRTILEIIRKAGVNFLVKSKAMTSEEIELNHYLGNN
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCC
GVTCLETDLGEWIIQLAGERPSHMVMPAIHKNREDVAELFSRETGLDCPPDIPHLVRVAR
CCEEEEHHHHHHHHHHCCCCCCCEECHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ETLRDGFLTGQVGLSGANVAMADSGAIGIVTNEGNGRLVTTLPRIHIALVGVDKIVPTLS
HHHHCCCEECCCCCCCCCEEEECCCEEEEEEECCCCEEEEEECCEEEEEEEHHHHHHHHH
EALDVITILPKNATGQKITSYVSFIKGPTGEGRELHIVLLDNGRTRLAADPDFSEALACV
HHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHH
KCGACANVCPIYEIVGGHVFGHIYVGGIGLVLTPFFHGLDKAEDILKLCIGCRKCNEVCA
HHCCCCCHHHHHHHHCCHHEEEHEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AKIDIEGLIVDLRDKIRKPAGQKFLFGTLMKNRALFHATLRTAYLAQKPFQSEGGRIRHL
EEECHHHEEEEHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
PLILNRETANRSLPPIAEKPFRDLIAEQPGTKKQGAASRETVLFYSGCLADFVYPEMCLD
EEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
TVKSLEALGYEVSFPQKQSCCGIPARYSGEMGVARDLAKINIDVLLEEDADYVVTICPTC
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEEECCCCEEEEECCCH
TMSLRHDFPKLLSTEPPWREKAERLAAKTFNFSELAARKAGSGIPTHETVNGGKETVTYH
HHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEH
DACHLKRGCGVHEEPRRVLRELVGVEIAEMTDCDKCCGFGGSYSIKYPEISQEVLKNKME
HHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCCEEECCHHHHHHHHHHHH
TIRETGARTVAVDCPGCKLQIEGGLEAAGTGIAVEHSATLLARRLVTP
HHHHCCCCEEEEECCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHCCC
>Mature Secondary Structure 
ARDVIRQKINDAFLRKALKNFAAAYPVARAKAFEGVDFEALRSRIAAFKKEGLARLPEM
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
VKEFTASAERSGATVHLCATPEEANRTILEIIRKAGVNFLVKSKAMTSEEIELNHYLGNN
HHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHCCCCEEEECCCCCCCCEEEEEEECCC
GVTCLETDLGEWIIQLAGERPSHMVMPAIHKNREDVAELFSRETGLDCPPDIPHLVRVAR
CCEEEEHHHHHHHHHHCCCCCCCEECHHHHCCHHHHHHHHHHCCCCCCCCCCHHHHHHHH
ETLRDGFLTGQVGLSGANVAMADSGAIGIVTNEGNGRLVTTLPRIHIALVGVDKIVPTLS
HHHHCCCEECCCCCCCCCEEEECCCEEEEEEECCCCEEEEEECCEEEEEEEHHHHHHHHH
EALDVITILPKNATGQKITSYVSFIKGPTGEGRELHIVLLDNGRTRLAADPDFSEALACV
HHHHEEEEECCCCCHHHHHHHHHHHCCCCCCCCEEEEEEECCCCEEEECCCCHHHHHHHH
KCGACANVCPIYEIVGGHVFGHIYVGGIGLVLTPFFHGLDKAEDILKLCIGCRKCNEVCA
HHCCCCCHHHHHHHHCCHHEEEHEECHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
AKIDIEGLIVDLRDKIRKPAGQKFLFGTLMKNRALFHATLRTAYLAQKPFQSEGGRIRHL
EEECHHHEEEEHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCEEEEE
PLILNRETANRSLPPIAEKPFRDLIAEQPGTKKQGAASRETVLFYSGCLADFVYPEMCLD
EEEEECCCCCCCCCCCCCHHHHHHHHCCCCCCCCCCCCCCEEEEEHHHHHHHHHHHHHHH
TVKSLEALGYEVSFPQKQSCCGIPARYSGEMGVARDLAKINIDVLLEEDADYVVTICPTC
HHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHEEEEEEEECCCCEEEEECCCH
TMSLRHDFPKLLSTEPPWREKAERLAAKTFNFSELAARKAGSGIPTHETVNGGKETVTYH
HHHHHHCCHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCEEEEH
DACHLKRGCGVHEEPRRVLRELVGVEIAEMTDCDKCCGFGGSYSIKYPEISQEVLKNKME
HHHHHHHCCCCCHHHHHHHHHHHCCCHHHHCCHHHHHCCCCCCEEECCHHHHHHHHHHHH
TIRETGARTVAVDCPGCKLQIEGGLEAAGTGIAVEHSATLLARRLVTP
HHHHCCCCEEEEECCCCEEEECCCCCCCCCCEEEEHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Fe [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA