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The map label for this gene is mdtA [H]

Identifier: 39996710

GI number: 39996710

Start: 1761729

End: 1762913

Strand: Direct

Name: mdtA [H]

Synonym: GSU1610

Alternate gene names: 39996710

Gene position: 1761729-1762913 (Clockwise)

Preceding gene: 39996709

Following gene: 39996711

Centisome position: 46.19

GC content: 61.77

Gene sequence:

>1185_bases
ATGGCTTTGATGAATGTGATGACAGCCTTTCGCACGCTTCGCCGCTGGGGACGGCATGCCGTTGCGGCGTCTGCGGTCGT
GCCCGCTCTCGCGTTGTGCGCCTGCTCCCCCAAGGAACAGAAACCAACGGTAAAGCCTCCGGTGCCGGTCGTGCTCGCAA
AGGTAGAGCGGAAGACGATTCCGGTTCAGATCAAGGCCATCGGCAATGTGGAGCCCTATGCCACGGTGGCGGTCAAGGCC
CAGGTGAGTGGTGAGGTGGTGAACGTTCACTTTACCGAAGGGCAGGACGTGAAAAAGGGCGATCTCCTGTTTGCCATAGA
TCCGCGCACCTATGCCGCCGCCCTGAAAAAAGCGGAAGCAAATCTTTCCCGGAATCTGGTCCAGGCGCGCAATGCCCGCC
AGGACGCGGAACGCTATGCCCAACTGCTGACAGAAGGGATCGTGACCCAGGAGCAGTATGAGCAGTACCGGACCAAGGCG
GAGGCTTTCGCGGCGGATGTTGCCGCCGACCGGGCCGCCGTGGAGAACGCCAAGGTCGAGCTCTCCTACTGCACCATACG
CTCACCCCTTTCGGGCCGAACCGGCAACCTGGCGGTGCATGCGGGGAACATCGTCAAGGCAAACGAGAATCCGCCGCTGG
TTACGATCAACCAGATAACCCCGGTCTACGTAACCTTTGCCATTCCCGAGAAAGACCTTGCCGAGATCAAGCACCGGCTG
GCGTCCGGACGGCTCGCGGTGGAGGCAATCATTCCCAATGATCAGGGACCGGCGGAGCAGGGGACCATCAGCTTTCTCGA
CAATGCGGTCGACGCCGCCACCGGTACCATCAAACTCAAGGGAATCTTCGAGAACAAGGGGCGGCGGCTCTGGCCCGGTC
AATTCGTCAACGTGGTCGTGACCCTCGCGTCCCGCGCCGACGCCGTTGTGGTGCCGTCCCAGGCACTCCAGACCGGACAG
AGCGGCCCCTACCTTTTTGTGGTAAAGGCTGACACCTCCGTGGAGGTTCGCCCCGTCACACCGGGTATCACCCATGAAGG
ACTCACTGTCATTGAACAGGGCGTCGCTCCGGGGGAAACGGTTGTGACCGACGGCCAGATGCGGCTCACCCCGAATGCCA
AGGTAACGGAAAAACGACCCGGAGGTGCCGGCGTTTCCCCCCCCGAACCGAGTAAGCGCCCATGA

Upstream 100 bases:

>100_bases
CTGGATCGGGAGGGAATTACCGTGACGGAAAAGGAGGGGGATTCCCTTTACGAGCAAAGTGCGCGAGACTGACACGTCCG
GACTGATTATGGAGTTCTGA

Downstream 100 bases:

>100_bases
ACATTGCCGAAATCTTCATCCGCCGGCCGGTCATGACGAGTCTCATCATGCTGGCGGTTATGCTTTTCGGCCTCATCGCC
TACGACAAGCTGCCGGTCAA

Product: RND family efflux transporter MFP subunit

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MALMNVMTAFRTLRRWGRHAVAASAVVPALALCACSPKEQKPTVKPPVPVVLAKVERKTIPVQIKAIGNVEPYATVAVKA
QVSGEVVNVHFTEGQDVKKGDLLFAIDPRTYAAALKKAEANLSRNLVQARNARQDAERYAQLLTEGIVTQEQYEQYRTKA
EAFAADVAADRAAVENAKVELSYCTIRSPLSGRTGNLAVHAGNIVKANENPPLVTINQITPVYVTFAIPEKDLAEIKHRL
ASGRLAVEAIIPNDQGPAEQGTISFLDNAVDAATGTIKLKGIFENKGRRLWPGQFVNVVVTLASRADAVVVPSQALQTGQ
SGPYLFVVKADTSVEVRPVTPGITHEGLTVIEQGVAPGETVVTDGQMRLTPNAKVTEKRPGGAGVSPPEPSKRP

Sequences:

>Translated_394_residues
MALMNVMTAFRTLRRWGRHAVAASAVVPALALCACSPKEQKPTVKPPVPVVLAKVERKTIPVQIKAIGNVEPYATVAVKA
QVSGEVVNVHFTEGQDVKKGDLLFAIDPRTYAAALKKAEANLSRNLVQARNARQDAERYAQLLTEGIVTQEQYEQYRTKA
EAFAADVAADRAAVENAKVELSYCTIRSPLSGRTGNLAVHAGNIVKANENPPLVTINQITPVYVTFAIPEKDLAEIKHRL
ASGRLAVEAIIPNDQGPAEQGTISFLDNAVDAATGTIKLKGIFENKGRRLWPGQFVNVVVTLASRADAVVVPSQALQTGQ
SGPYLFVVKADTSVEVRPVTPGITHEGLTVIEQGVAPGETVVTDGQMRLTPNAKVTEKRPGGAGVSPPEPSKRP
>Mature_393_residues
ALMNVMTAFRTLRRWGRHAVAASAVVPALALCACSPKEQKPTVKPPVPVVLAKVERKTIPVQIKAIGNVEPYATVAVKAQ
VSGEVVNVHFTEGQDVKKGDLLFAIDPRTYAAALKKAEANLSRNLVQARNARQDAERYAQLLTEGIVTQEQYEQYRTKAE
AFAADVAADRAAVENAKVELSYCTIRSPLSGRTGNLAVHAGNIVKANENPPLVTINQITPVYVTFAIPEKDLAEIKHRLA
SGRLAVEAIIPNDQGPAEQGTISFLDNAVDAATGTIKLKGIFENKGRRLWPGQFVNVVVTLASRADAVVVPSQALQTGQS
GPYLFVVKADTSVEVRPVTPGITHEGLTVIEQGVAPGETVVTDGQMRLTPNAKVTEKRPGGAGVSPPEPSKRP

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=331, Percent_Identity=35.6495468277946, Blast_Score=217, Evalue=1e-57,
Organism=Escherichia coli, GI1789929, Length=353, Percent_Identity=30.3116147308782, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789665, Length=376, Percent_Identity=31.1170212765957, Blast_Score=160, Evalue=9e-41,
Organism=Escherichia coli, GI1786668, Length=360, Percent_Identity=32.7777777777778, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1790519, Length=260, Percent_Identity=28.8461538461538, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI87081951, Length=162, Percent_Identity=28.3950617283951, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1789637, Length=130, Percent_Identity=32.3076923076923, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42137; Mature: 42006

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALMNVMTAFRTLRRWGRHAVAASAVVPALALCACSPKEQKPTVKPPVPVVLAKVERKTI
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCC
PVQIKAIGNVEPYATVAVKAQVSGEVVNVHFTEGQDVKKGDLLFAIDPRTYAAALKKAEA
CEEEEEECCCCCEEEEEEEEEECCEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHH
NLSRNLVQARNARQDAERYAQLLTEGIVTQEQYEQYRTKAEAFAADVAADRAAVENAKVE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LSYCTIRSPLSGRTGNLAVHAGNIVKANENPPLVTINQITPVYVTFAIPEKDLAEIKHRL
EEEEEECCCCCCCCCCEEEEECCEEEECCCCCEEEECCCCEEEEEEECCCHHHHHHHHHH
ASGRLAVEAIIPNDQGPAEQGTISFLDNAVDAATGTIKLKGIFENKGRRLWPGQFVNVVV
HCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCEECCHHHHHHHH
TLASRADAVVVPSQALQTGQSGPYLFVVKADTSVEVRPVTPGITHEGLTVIEQGVAPGET
HHHCCCCEEEECHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCHHHHHCCCCCCCE
VVTDGQMRLTPNAKVTEKRPGGAGVSPPEPSKRP
EEECCEEEECCCCCEECCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALMNVMTAFRTLRRWGRHAVAASAVVPALALCACSPKEQKPTVKPPVPVVLAKVERKTI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCCC
PVQIKAIGNVEPYATVAVKAQVSGEVVNVHFTEGQDVKKGDLLFAIDPRTYAAALKKAEA
CEEEEEECCCCCEEEEEEEEEECCEEEEEEECCCCCCCCCCEEEEECCHHHHHHHHHHHH
NLSRNLVQARNARQDAERYAQLLTEGIVTQEQYEQYRTKAEAFAADVAADRAAVENAKVE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEE
LSYCTIRSPLSGRTGNLAVHAGNIVKANENPPLVTINQITPVYVTFAIPEKDLAEIKHRL
EEEEEECCCCCCCCCCEEEEECCEEEECCCCCEEEECCCCEEEEEEECCCHHHHHHHHHH
ASGRLAVEAIIPNDQGPAEQGTISFLDNAVDAATGTIKLKGIFENKGRRLWPGQFVNVVV
HCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCEEEEEEEEECCCCEECCHHHHHHHH
TLASRADAVVVPSQALQTGQSGPYLFVVKADTSVEVRPVTPGITHEGLTVIEQGVAPGET
HHHCCCCEEEECHHHHHCCCCCCEEEEEECCCCEEEEECCCCCCCCCHHHHHCCCCCCCE
VVTDGQMRLTPNAKVTEKRPGGAGVSPPEPSKRP
EEECCEEEECCCCCEECCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA