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The map label for this gene is pbpG [H]

Identifier: 39996661

GI number: 39996661

Start: 1714573

End: 1716561

Strand: Direct

Name: pbpG [H]

Synonym: GSU1561

Alternate gene names: 39996661

Gene position: 1714573-1716561 (Clockwise)

Preceding gene: 39996660

Following gene: 39996662

Centisome position: 44.95

GC content: 64.35

Gene sequence:

>1989_bases
ATGTCAAACCTGCTGTATGGCCTGACCCTGTTCATCGTCGTTGCCCTGACCCTGGCATCCCCGGCCGGGGCCCAGGATGC
CATCGCCACTCATCCAATCCAGCCCGCCGGCTATTCTTCCATAAAGGTTTTCGACCGTAACGGCCGGTTTGCGGGCCGGA
TTCTTCCCGAAAAGCGCTACTGGGTTCCCATCGACCGCATCCCTGCCTTCCTGCAGAAGGCGGTTGTGGCGGTGGAGGAT
GCCCGCTTCTACGAGCATAGCGGCATCGATGTGCGGGGTATCGCCCGTGCCCTGGTGAAGGACGTGGTCAAGGGGCGGCT
GGCCGAGGGTGGCTCGACCATTACCCAGCAGCTGATCAAGAACAAGTATCTCTCCGGCGAGAAGAGCATCGAGCGCAAAC
TGGAAGAAGCCCGGCTGGCAATGGACTACGAGAAGAAATACAGCAAGAAGCAGATCCTTGAGATGTATTTCAATGAAATT
TACTACGGCCGGGGAGCCTGGGGGATCGCCCAGGCGGCCCGCGTCTACTTCGACAAGAACCCTGAGGAACTGACCGAGGC
CGAATGCGCCCTGCTGGCGGGCGTGCCCAAAAATCCGGGCCGCTACAATCCGTTGGGCAAGGCGGCTGACGTGGGGCGGC
GCAGGGACGTGGTCCTCAAGCGGATGACGGACCTCAATATGATTTCCGCCCGGCAGAAGCAGAAGCTGCGCAGCCAGCGG
GTGGCCGTTACCCCGCCGGACCAGGCATCGTGGTATCTGGCCCATATCCGGAACCTGCTGGTGGAGCGGTACGGCCCCCA
GGTCATCGAGGCGGGGGGACTGGAAGTGACAGCGGCCATGGATCTGAACCTGCAGAAACTAGCCGAAAAGACCCTGCGGG
AAGGGGTGAAGCGGGTTTCGCCCGACCTTCAGGGAGCGCTGATGTCCCTGGATCCCGCCACTGGCGATGTACTGGCGGCC
GTGGGGGGCGTGGACTTCGCCAAGAGCTCCTATGACCGGGCATTCCTGGCGCGGCGCCAGCCCGGCTCGGCAATAAAGCC
CCTGATCTATGCGGCTGCCCTGGAAAAGGGGATCACTGCCGCGAGCGTCTGGGATGATTCCCCGGTTGCCTACGTCCGCG
GCGCCAACCAAACCTGGAAGCCCAGGAACTACGGCGGCGAGCAGTACGGGGAACTTTCCCTGAGGAAGGCCCTGGCCTAC
TCGAACAACGTCATCACAGTCAAGGTGCTGGAGACGATCGGCGTTCCCTACTTCGTGGAGATTGCCAGGAATCTGGGACT
GTCGCTCCGATCGCCCAACGACCTCTCGCTGGCCCTGGGCACCGACGAGGTGACCCTGCGTGATCTCGTTTCGGCGTACA
CCCCCCTGGCCAACGGAGGACTCCGGGCCGAAGCCAGGACCGTGCTCCGGATCTACGACAAGCGCCGTCGCGCCTGGACC
GACAATCCGCCGGCCGTCACTCAGGCCATCTCGCCCGCCGCGGCCTATGTCACGACCCAGATGCTCAAGGACGTGATGGT
GTACGGCACGGCCAAGTCGCTCAGGAAGTTCAGCCAGGCCCGGCCGGCCGCCGGCAAGACCGGCACCACCGACGATTACC
GGGACGCTTGGTTCATCGGCTATACTCCGGGTGTCGTTACCGGCATCTGGGTCGGCCACGACAAGCCCAGGCCGGGAGGG
AAAGGGTTCACGGGGGGTACCGTGGCCGCGCCCATCTGGGAGCGGTTCATGGGACCGGCCCTGTCCGGTCGGCCGGCCGC
CGACTTCGCCCGGCCGGAAACGGTCGTTGCCGTGACCGTGGACCCTGCCACGGGATACCGGGCAGCGCCGGAGTGCCCGG
AACAGCGGGAAGAATTATTTATTGCCGGCACTGAGCCGGTCGCATACTGCCCTGCCCACGGCGGGGAGCTCCTGATGCCC
GAATCGCCCGATCTGCCGGTGCCGGAAGGGGAAACCCGGGAGCCTGCGGCCACCGACAATCCGATGTGA

Upstream 100 bases:

>100_bases
TCACAAACCACGCACGTGCCACCGTCACAGCTGCGGCAGGGCTGCACAGCCGGCGGACGTCCCGTGCAATCGGGTAATAT
TGTCTGCAAGGATAGATGTG

Downstream 100 bases:

>100_bases
CAAGGAGGCGTGCATGAACGTGATGGTTGATCTGTGCATCGTGCCGATCGGCGTGGGAGTTTCCCTTTCGCCTTACGTGG
CGGCCTGTCAGAAGGTGCTT

Product: 1A family penicillin-binding protein

Products: NA

Alternate protein names: PBP-2D; PBP2d [H]

Number of amino acids: Translated: 662; Mature: 661

Protein sequence:

>662_residues
MSNLLYGLTLFIVVALTLASPAGAQDAIATHPIQPAGYSSIKVFDRNGRFAGRILPEKRYWVPIDRIPAFLQKAVVAVED
ARFYEHSGIDVRGIARALVKDVVKGRLAEGGSTITQQLIKNKYLSGEKSIERKLEEARLAMDYEKKYSKKQILEMYFNEI
YYGRGAWGIAQAARVYFDKNPEELTEAECALLAGVPKNPGRYNPLGKAADVGRRRDVVLKRMTDLNMISARQKQKLRSQR
VAVTPPDQASWYLAHIRNLLVERYGPQVIEAGGLEVTAAMDLNLQKLAEKTLREGVKRVSPDLQGALMSLDPATGDVLAA
VGGVDFAKSSYDRAFLARRQPGSAIKPLIYAAALEKGITAASVWDDSPVAYVRGANQTWKPRNYGGEQYGELSLRKALAY
SNNVITVKVLETIGVPYFVEIARNLGLSLRSPNDLSLALGTDEVTLRDLVSAYTPLANGGLRAEARTVLRIYDKRRRAWT
DNPPAVTQAISPAAAYVTTQMLKDVMVYGTAKSLRKFSQARPAAGKTGTTDDYRDAWFIGYTPGVVTGIWVGHDKPRPGG
KGFTGGTVAAPIWERFMGPALSGRPAADFARPETVVAVTVDPATGYRAAPECPEQREELFIAGTEPVAYCPAHGGELLMP
ESPDLPVPEGETREPAATDNPM

Sequences:

>Translated_662_residues
MSNLLYGLTLFIVVALTLASPAGAQDAIATHPIQPAGYSSIKVFDRNGRFAGRILPEKRYWVPIDRIPAFLQKAVVAVED
ARFYEHSGIDVRGIARALVKDVVKGRLAEGGSTITQQLIKNKYLSGEKSIERKLEEARLAMDYEKKYSKKQILEMYFNEI
YYGRGAWGIAQAARVYFDKNPEELTEAECALLAGVPKNPGRYNPLGKAADVGRRRDVVLKRMTDLNMISARQKQKLRSQR
VAVTPPDQASWYLAHIRNLLVERYGPQVIEAGGLEVTAAMDLNLQKLAEKTLREGVKRVSPDLQGALMSLDPATGDVLAA
VGGVDFAKSSYDRAFLARRQPGSAIKPLIYAAALEKGITAASVWDDSPVAYVRGANQTWKPRNYGGEQYGELSLRKALAY
SNNVITVKVLETIGVPYFVEIARNLGLSLRSPNDLSLALGTDEVTLRDLVSAYTPLANGGLRAEARTVLRIYDKRRRAWT
DNPPAVTQAISPAAAYVTTQMLKDVMVYGTAKSLRKFSQARPAAGKTGTTDDYRDAWFIGYTPGVVTGIWVGHDKPRPGG
KGFTGGTVAAPIWERFMGPALSGRPAADFARPETVVAVTVDPATGYRAAPECPEQREELFIAGTEPVAYCPAHGGELLMP
ESPDLPVPEGETREPAATDNPM
>Mature_661_residues
SNLLYGLTLFIVVALTLASPAGAQDAIATHPIQPAGYSSIKVFDRNGRFAGRILPEKRYWVPIDRIPAFLQKAVVAVEDA
RFYEHSGIDVRGIARALVKDVVKGRLAEGGSTITQQLIKNKYLSGEKSIERKLEEARLAMDYEKKYSKKQILEMYFNEIY
YGRGAWGIAQAARVYFDKNPEELTEAECALLAGVPKNPGRYNPLGKAADVGRRRDVVLKRMTDLNMISARQKQKLRSQRV
AVTPPDQASWYLAHIRNLLVERYGPQVIEAGGLEVTAAMDLNLQKLAEKTLREGVKRVSPDLQGALMSLDPATGDVLAAV
GGVDFAKSSYDRAFLARRQPGSAIKPLIYAAALEKGITAASVWDDSPVAYVRGANQTWKPRNYGGEQYGELSLRKALAYS
NNVITVKVLETIGVPYFVEIARNLGLSLRSPNDLSLALGTDEVTLRDLVSAYTPLANGGLRAEARTVLRIYDKRRRAWTD
NPPAVTQAISPAAAYVTTQMLKDVMVYGTAKSLRKFSQARPAAGKTGTTDDYRDAWFIGYTPGVVTGIWVGHDKPRPGGK
GFTGGTVAAPIWERFMGPALSGRPAADFARPETVVAVTVDPATGYRAAPECPEQREELFIAGTEPVAYCPAHGGELLMPE
SPDLPVPEGETREPAATDNPM

Specific function: Involved in the polymerization and cross-linking of spore peptidoglycan. May be required for synthesis of the spore germ cell wall, the first layer of peptidoglycan synthesized on the surface of the inner forespore membrane [H]

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786343, Length=598, Percent_Identity=31.1036789297659, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI1788867, Length=517, Percent_Identity=29.7872340425532, Blast_Score=181, Evalue=1e-46,
Organism=Escherichia coli, GI87082258, Length=266, Percent_Identity=35.7142857142857, Blast_Score=166, Evalue=4e-42,
Organism=Escherichia coli, GI1789601, Length=176, Percent_Identity=38.0681818181818, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR001264
- InterPro:   IPR011816
- InterPro:   IPR001460 [H]

Pfam domain/function: PF00912 Transgly; PF00905 Transpeptidase [H]

EC number: 2.4.1.129; 3.4.-.- [C]

Molecular weight: Translated: 72301; Mature: 72170

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLLYGLTLFIVVALTLASPAGAQDAIATHPIQPAGYSSIKVFDRNGRFAGRILPEKRY
CCCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCC
WVPIDRIPAFLQKAVVAVEDARFYEHSGIDVRGIARALVKDVVKGRLAEGGSTITQQLIK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NKYLSGEKSIERKLEEARLAMDYEKKYSKKQILEMYFNEIYYGRGAWGIAQAARVYFDKN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PEELTEAECALLAGVPKNPGRYNPLGKAADVGRRRDVVLKRMTDLNMISARQKQKLRSQR
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VAVTPPDQASWYLAHIRNLLVERYGPQVIEAGGLEVTAAMDLNLQKLAEKTLREGVKRVS
EEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHC
PDLQGALMSLDPATGDVLAAVGGVDFAKSSYDRAFLARRQPGSAIKPLIYAAALEKGITA
CCHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCE
ASVWDDSPVAYVRGANQTWKPRNYGGEQYGELSLRKALAYSNNVITVKVLETIGVPYFVE
EECCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHH
IARNLGLSLRSPNDLSLALGTDEVTLRDLVSAYTPLANGGLRAEARTVLRIYDKRRRAWT
HHHHCCCEECCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
DNPPAVTQAISPAAAYVTTQMLKDVMVYGTAKSLRKFSQARPAAGKTGTTDDYRDAWFIG
CCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
YTPGVVTGIWVGHDKPRPGGKGFTGGTVAAPIWERFMGPALSGRPAADFARPETVVAVTV
CCCCHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEE
DPATGYRAAPECPEQREELFIAGTEPVAYCPAHGGELLMPESPDLPVPEGETREPAATDN
CCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
PM
CC
>Mature Secondary Structure 
SNLLYGLTLFIVVALTLASPAGAQDAIATHPIQPAGYSSIKVFDRNGRFAGRILPEKRY
CCHHHHHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCEEEEEECCCCEEEEECCCCCC
WVPIDRIPAFLQKAVVAVEDARFYEHSGIDVRGIARALVKDVVKGRLAEGGSTITQQLIK
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
NKYLSGEKSIERKLEEARLAMDYEKKYSKKQILEMYFNEIYYGRGAWGIAQAARVYFDKN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCC
PEELTEAECALLAGVPKNPGRYNPLGKAADVGRRRDVVLKRMTDLNMISARQKQKLRSQR
HHHHHHHHHHHHCCCCCCCCCCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
VAVTPPDQASWYLAHIRNLLVERYGPQVIEAGGLEVTAAMDLNLQKLAEKTLREGVKRVS
EEECCCCCHHHHHHHHHHHHHHHCCCCEEECCCEEEEEEECCCHHHHHHHHHHHHHHHHC
PDLQGALMSLDPATGDVLAAVGGVDFAKSSYDRAFLARRQPGSAIKPLIYAAALEKGITA
CCHHHHHEECCCCCCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCE
ASVWDDSPVAYVRGANQTWKPRNYGGEQYGELSLRKALAYSNNVITVKVLETIGVPYFVE
EECCCCCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCHHHHH
IARNLGLSLRSPNDLSLALGTDEVTLRDLVSAYTPLANGGLRAEARTVLRIYDKRRRAWT
HHHHCCCEECCCCCCEEEECCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
DNPPAVTQAISPAAAYVTTQMLKDVMVYGTAKSLRKFSQARPAAGKTGTTDDYRDAWFIG
CCCCHHHHHCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCCCEEEEE
YTPGVVTGIWVGHDKPRPGGKGFTGGTVAAPIWERFMGPALSGRPAADFARPETVVAVTV
CCCCHHEEEEECCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEEE
DPATGYRAAPECPEQREELFIAGTEPVAYCPAHGGELLMPESPDLPVPEGETREPAATDN
CCCCCCCCCCCCCCCCCCEEEECCCCEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCC
PM
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Aminoacyltransferases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]