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The map label for this gene is pilC [H]

Identifier: 39996593

GI number: 39996593

Start: 1637811

End: 1639028

Strand: Direct

Name: pilC [H]

Synonym: GSU1493

Alternate gene names: 39996593

Gene position: 1637811-1639028 (Clockwise)

Preceding gene: 39996592

Following gene: 39996594

Centisome position: 42.94

GC content: 55.09

Gene sequence:

>1218_bases
ATGCCCAAGTTCAACTGGGAAGCAAGAAGCAGGACCGGTTCCGTTCAGAAGGGGGTCATGGAGGCGGCCAGCGCAGCCGC
CGTGGAGGCCCAGCTCAAAAAATACGGCTTCGGCAGCATTTCCATAAAGGAAGAGGGAAAAGGCCTCTCCATGGAGATCA
AGCTTCCCGGCTTTGCCCCCAAGGTGGAAACCAAGGATCTCGTGGTATTCACGCGGCAGTTCGCCACCATGATCGACTCA
GGCCTGCCTTTGGTGCAATGCCTTGACATCCTCTCCAGCCAACAGGAAAACAAAACCTTCAAGGATGTTCTCATTAGGGT
CAAGGAGTCGGTTGAAGGGGGCTCAACCTTTGCTGATGCTCTGTCCAAGCATCCCAAGGTCTTTGACCAGCTCTATGTGA
ACCTGGTGGCTGCTGGCGAGGTCGGCGGCATCCTCGACACAATCCTGAACCGTCTTGCCGCCTATATCGAAAAAGCGATG
AAACTCAAGAAGCAGGTCAAGGGGGCCATGGTCTATCCGACAACGATCATGGCAATTGCCGTCATCGTCGTCGGCGTCAT
TCTGATATTCGTCATTCCGACTTTTGCCAAGATGTTCCAGGAGTTTGGCGGAGAACTGCCTGGGCCGACCAAGTTTGTCA
TCAATCTCAGTAATTTCATTGTTAAATACATTCTCCTGATTATCGGCCTTATCTTTGCCCTTATCGTCGGATTCAAAAAG
TATTACGCCACAACCGGCGGCAGAAAAAAAATAGACGCCTTTGCCCTCAAAGCACCCATTGCCGGACCAATCATCAAGAA
GGTGTCCGTTGCCCGGTTTACCCGGACCCTTGGAACCCTCATCTCCAGTGGGGTGCCGATCATGGACGGGCTCGAGATCG
TTGCCAAGACCGCCGGCAACAAGGTGGTGGAGGAGGCGGTGTACAAGGTCCGGCAGGCCATTTCGGAAGGTAAGACCATG
GCCGAGCCGCTCCAGGAGTGTGGCGTCTTCCCCCCCATGGTCGTGCAGATGATCTCCGTGGGCGAGGCCACCGGTGCCAT
GGATGCCATGCTGAGCAAGATCGCCGATTTCTACGATGATGAAGTGGACGAGGCCGTGAGTGCCATGACCGCCCTGATGG
AGCCGATGCTGATGGTGTTTCTCGGCACCACTGTCGGCGGTCTCGTCATTGCCATGTACCTGCCGATCTTCAAGCTTGCG
GGAACTGTTGGCGGCTAA

Upstream 100 bases:

>100_bases
CGAACTCAAGCAGATGCTGGCCAGCGCCCAGCGGCCACCGGGTCAGCGCCCTCAGATGAGGTAACCGCCGCCGGATCGAT
CTGTACACAGGAGGAGAAAG

Downstream 100 bases:

>100_bases
ATGATGAAGGAAAGCCGGCGCGTTGTCTGGTTCATCCTTGCCCGGATGATTGTGGTGTCACTGTTTCTGGTGTCCACCAT
CATCCTGAGAATGAAGGGGA

Product: type IV pilus biogenesis protein PilC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MPKFNWEARSRTGSVQKGVMEAASAAAVEAQLKKYGFGSISIKEEGKGLSMEIKLPGFAPKVETKDLVVFTRQFATMIDS
GLPLVQCLDILSSQQENKTFKDVLIRVKESVEGGSTFADALSKHPKVFDQLYVNLVAAGEVGGILDTILNRLAAYIEKAM
KLKKQVKGAMVYPTTIMAIAVIVVGVILIFVIPTFAKMFQEFGGELPGPTKFVINLSNFIVKYILLIIGLIFALIVGFKK
YYATTGGRKKIDAFALKAPIAGPIIKKVSVARFTRTLGTLISSGVPIMDGLEIVAKTAGNKVVEEAVYKVRQAISEGKTM
AEPLQECGVFPPMVVQMISVGEATGAMDAMLSKIADFYDDEVDEAVSAMTALMEPMLMVFLGTTVGGLVIAMYLPIFKLA
GTVGG

Sequences:

>Translated_405_residues
MPKFNWEARSRTGSVQKGVMEAASAAAVEAQLKKYGFGSISIKEEGKGLSMEIKLPGFAPKVETKDLVVFTRQFATMIDS
GLPLVQCLDILSSQQENKTFKDVLIRVKESVEGGSTFADALSKHPKVFDQLYVNLVAAGEVGGILDTILNRLAAYIEKAM
KLKKQVKGAMVYPTTIMAIAVIVVGVILIFVIPTFAKMFQEFGGELPGPTKFVINLSNFIVKYILLIIGLIFALIVGFKK
YYATTGGRKKIDAFALKAPIAGPIIKKVSVARFTRTLGTLISSGVPIMDGLEIVAKTAGNKVVEEAVYKVRQAISEGKTM
AEPLQECGVFPPMVVQMISVGEATGAMDAMLSKIADFYDDEVDEAVSAMTALMEPMLMVFLGTTVGGLVIAMYLPIFKLA
GTVGG
>Mature_404_residues
PKFNWEARSRTGSVQKGVMEAASAAAVEAQLKKYGFGSISIKEEGKGLSMEIKLPGFAPKVETKDLVVFTRQFATMIDSG
LPLVQCLDILSSQQENKTFKDVLIRVKESVEGGSTFADALSKHPKVFDQLYVNLVAAGEVGGILDTILNRLAAYIEKAMK
LKKQVKGAMVYPTTIMAIAVIVVGVILIFVIPTFAKMFQEFGGELPGPTKFVINLSNFIVKYILLIIGLIFALIVGFKKY
YATTGGRKKIDAFALKAPIAGPIIKKVSVARFTRTLGTLISSGVPIMDGLEIVAKTAGNKVVEEAVYKVRQAISEGKTMA
EPLQECGVFPPMVVQMISVGEATGAMDAMLSKIADFYDDEVDEAVSAMTALMEPMLMVFLGTTVGGLVIAMYLPIFKLAG
TVGG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=403, Percent_Identity=26.302729528536, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1786295, Length=402, Percent_Identity=27.363184079602, Blast_Score=160, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 43563; Mature: 43432

Theoretical pI: Translated: 9.45; Mature: 9.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPKFNWEARSRTGSVQKGVMEAASAAAVEAQLKKYGFGSISIKEEGKGLSMEIKLPGFAP
CCCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCC
KVETKDLVVFTRQFATMIDSGLPLVQCLDILSSQQENKTFKDVLIRVKESVEGGSTFADA
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LSKHPKVFDQLYVNLVAAGEVGGILDTILNRLAAYIEKAMKLKKQVKGAMVYPTTIMAIA
HHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
VIVVGVILIFVIPTFAKMFQEFGGELPGPTKFVINLSNFIVKYILLIIGLIFALIVGFKK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYATTGGRKKIDAFALKAPIAGPIIKKVSVARFTRTLGTLISSGVPIMDGLEIVAKTAGN
HHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCH
KVVEEAVYKVRQAISEGKTMAEPLQECGVFPPMVVQMISVGEATGAMDAMLSKIADFYDD
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EVDEAVSAMTALMEPMLMVFLGTTVGGLVIAMYLPIFKLAGTVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PKFNWEARSRTGSVQKGVMEAASAAAVEAQLKKYGFGSISIKEEGKGLSMEIKLPGFAP
CCCCCCHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCEEEEECCCCCC
KVETKDLVVFTRQFATMIDSGLPLVQCLDILSSQQENKTFKDVLIRVKESVEGGSTFADA
CCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHHH
LSKHPKVFDQLYVNLVAAGEVGGILDTILNRLAAYIEKAMKLKKQVKGAMVYPTTIMAIA
HHHCHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
VIVVGVILIFVIPTFAKMFQEFGGELPGPTKFVINLSNFIVKYILLIIGLIFALIVGFKK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YYATTGGRKKIDAFALKAPIAGPIIKKVSVARFTRTLGTLISSGVPIMDGLEIVAKTAGN
HHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCH
KVVEEAVYKVRQAISEGKTMAEPLQECGVFPPMVVQMISVGEATGAMDAMLSKIADFYDD
HHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
EVDEAVSAMTALMEPMLMVFLGTTVGGLVIAMYLPIFKLAGTVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]