Click here to switch to the map view.

The map label for this gene is atoS [C]

Identifier: 39996543

GI number: 39996543

Start: 1579416

End: 1581380

Strand: Reverse

Name: atoS [C]

Synonym: GSU1443

Alternate gene names: 39996543

Gene position: 1581380-1579416 (Counterclockwise)

Preceding gene: 39996544

Following gene: 39996539

Centisome position: 41.46

GC content: 55.17

Gene sequence:

>1965_bases
ATGGGCATGCACGACACGCTAAAACAACGGCACGACAGTCTTGGTCTCAGGTTTTTCCTCCTCTTTGCATCAACGATCGC
CGTTATATCCATATCGTTCACCGTTCTGTTTTACCAGCAGCAGCGACGCATACTTCGGGAAAACGTCACCCATGAGGGTC
AGATTCTCGCACGCCTCCTGGCCCACAACGCCCGGCTGGGCGTCTTTGCGGAGAACGGCGAACTACTCAAAGACCCGGTG
GAGGGCATTCTGCAGCATGATGGGGTACTTTTCGTCTCGGTCATTTCAGCAGCCGGCACCCCCATCAGGGAGCAGGCCCA
TGAAAAGATGCTCAAGACTCCGGAAAGGAAAATACCCAACTGGAGTGTGCATTTCAGCGATACACGCTCAAGTAGAGTCC
CCCACACCTTCGAGGAAGCCGAGCTTTTCGAGTTCTGGGCGCCGATCGTCTCCATCGCTCCGTTCCAGAGCACCGATGCG
CTGATCCTAGGACACGAGGCGCAGGGCAAGGAAAAGATCCTGGGGTATGCCCGTATCATTGTGGACAAACACCCCCTCAA
GCGACGTCTCGACACGCTTTTGCTCATCTGCAGCACCCTTACCGGCGGATTCCTGGTATTGAGCACCATTCTCACGTATC
TTGTGGTACGCCGGATCACCAATCCGCTCGACCGACTCACTGTCGGCATTAAGGCATTGGAGCAGGGTGGCGCTTTCGTC
CCGGTAAAGGTCGAGCGCAATCACGAAATCGGACGTCTGGCCAATGCCTTCAACCATATGGCGGAGACGCTTAAAAAGCG
CGAAGCGGAGAAAGAACTGCTGGCCGAAGAGCTGCGTCACGCCCAGAAGATGGAAGCAATCGGTACCCTTGCAGGAGGGG
TGGCCCACGACTTCAACAATATCCTTACGGCTATCGTCGGCTTCGGCACGCTCCTGCAGCGCAGTCTGAACAAAGATAAC
CCCTACCAGATTTATGTGGACCAGATACTTAACGCTGCCGATCGCGCCACGACGCTGGTAAAACGGCTGCTGGCCTTTGG
CCGCAAACAGGTTATCACGCCCCTCCCCACTGATTTGAACGGGATCATCCAGAGTATCGAGAAACTTCTGGCCCGCCTCG
TGAGCGAGGATGTGGAGTTCAAGGTATCTCTCTTCAACGAACCTCTCGTCTGCCATGTGGATTCAGGACAAATAGACCAG
ATACTCATGAATCTCGTAACCAATGCCCGCGATGCCATGCCGTCAGGAGGGACTCTCACGCTGACGACCGATGCGACGGT
TCTGAACGAAAATTCCTTCAGTTCGCTGGAACAGTGCCGGCCGGGACGTTATGCCGTTCTGACCGTCAGCGACACGGGCC
TTGGCATGGACCAGGAGACAAAAGAGCGGATTTTCGACCCCTTCTTCACAACAAAGGAGGTTGGAAAAGGCACTGGTCTC
GGCCTGTCGATGGTATATGGCATCGTGCGACAACATGAAGGGTTCGTCACCGTTGATTCCGAACCGGGCGCCGGCACCAC
CTTCCGCATCTATCTTCCGATCGTGGCATTGACGGCGAGACATGAAGAGGAAGCACCACCGATCGTGGCAAAGGGGAACA
GGGAAACCGTCCTGCTGGCGGAGGACGACAAAGCGGTCAGAAAGCTTTCCCGTCACGTGCTCGAACGTAACGGTTACGAG
GTAATTGAAGCAGCCGATGGAAACGACGCGGTCAAAAAATTTGCCGAGTCCGTCAACAAGATCGATCTCGTCCTGCTCGA
CGTGGTGATGCCCGGCAAGAACGGCCAGGTTGCCTTCGAGGAAATGAAACGAATCCAACCAGCTATCAAAGCCCTCTTCA
TCAGCGGCTACACCAAGGACATCATCGGCAGCAAGGGTTTCCTGGCCGAAGATATCAATTTCATCGCCAAACCGGTCAAG
CCTGATCAACTGATCGCACGAGTACAGGAAGCATTGAAGAGCTGA

Upstream 100 bases:

>100_bases
GCATGGTCATGACGGTTAATGCGAAAGTTGCGCGTAAACTCGGTCTGACACTATCCGAAGAGGCCCTGGGAAGGGCCAGG
GTAATTCGATAGGAGAGACC

Downstream 100 bases:

>100_bases
ACGAGTCCCTAAGCAGCATCCGTACACAAAAAAGCCCGCCGAAGCGGGCTTTTTTGTACATTCCCTCCATCTGAGGAGAG
CTGTTATTTCTTGCCATCCA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 654; Mature: 653

Protein sequence:

>654_residues
MGMHDTLKQRHDSLGLRFFLLFASTIAVISISFTVLFYQQQRRILRENVTHEGQILARLLAHNARLGVFAENGELLKDPV
EGILQHDGVLFVSVISAAGTPIREQAHEKMLKTPERKIPNWSVHFSDTRSSRVPHTFEEAELFEFWAPIVSIAPFQSTDA
LILGHEAQGKEKILGYARIIVDKHPLKRRLDTLLLICSTLTGGFLVLSTILTYLVVRRITNPLDRLTVGIKALEQGGAFV
PVKVERNHEIGRLANAFNHMAETLKKREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNNILTAIVGFGTLLQRSLNKDN
PYQIYVDQILNAADRATTLVKRLLAFGRKQVITPLPTDLNGIIQSIEKLLARLVSEDVEFKVSLFNEPLVCHVDSGQIDQ
ILMNLVTNARDAMPSGGTLTLTTDATVLNENSFSSLEQCRPGRYAVLTVSDTGLGMDQETKERIFDPFFTTKEVGKGTGL
GLSMVYGIVRQHEGFVTVDSEPGAGTTFRIYLPIVALTARHEEEAPPIVAKGNRETVLLAEDDKAVRKLSRHVLERNGYE
VIEAADGNDAVKKFAESVNKIDLVLLDVVMPGKNGQVAFEEMKRIQPAIKALFISGYTKDIIGSKGFLAEDINFIAKPVK
PDQLIARVQEALKS

Sequences:

>Translated_654_residues
MGMHDTLKQRHDSLGLRFFLLFASTIAVISISFTVLFYQQQRRILRENVTHEGQILARLLAHNARLGVFAENGELLKDPV
EGILQHDGVLFVSVISAAGTPIREQAHEKMLKTPERKIPNWSVHFSDTRSSRVPHTFEEAELFEFWAPIVSIAPFQSTDA
LILGHEAQGKEKILGYARIIVDKHPLKRRLDTLLLICSTLTGGFLVLSTILTYLVVRRITNPLDRLTVGIKALEQGGAFV
PVKVERNHEIGRLANAFNHMAETLKKREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNNILTAIVGFGTLLQRSLNKDN
PYQIYVDQILNAADRATTLVKRLLAFGRKQVITPLPTDLNGIIQSIEKLLARLVSEDVEFKVSLFNEPLVCHVDSGQIDQ
ILMNLVTNARDAMPSGGTLTLTTDATVLNENSFSSLEQCRPGRYAVLTVSDTGLGMDQETKERIFDPFFTTKEVGKGTGL
GLSMVYGIVRQHEGFVTVDSEPGAGTTFRIYLPIVALTARHEEEAPPIVAKGNRETVLLAEDDKAVRKLSRHVLERNGYE
VIEAADGNDAVKKFAESVNKIDLVLLDVVMPGKNGQVAFEEMKRIQPAIKALFISGYTKDIIGSKGFLAEDINFIAKPVK
PDQLIARVQEALKS
>Mature_653_residues
GMHDTLKQRHDSLGLRFFLLFASTIAVISISFTVLFYQQQRRILRENVTHEGQILARLLAHNARLGVFAENGELLKDPVE
GILQHDGVLFVSVISAAGTPIREQAHEKMLKTPERKIPNWSVHFSDTRSSRVPHTFEEAELFEFWAPIVSIAPFQSTDAL
ILGHEAQGKEKILGYARIIVDKHPLKRRLDTLLLICSTLTGGFLVLSTILTYLVVRRITNPLDRLTVGIKALEQGGAFVP
VKVERNHEIGRLANAFNHMAETLKKREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNNILTAIVGFGTLLQRSLNKDNP
YQIYVDQILNAADRATTLVKRLLAFGRKQVITPLPTDLNGIIQSIEKLLARLVSEDVEFKVSLFNEPLVCHVDSGQIDQI
LMNLVTNARDAMPSGGTLTLTTDATVLNENSFSSLEQCRPGRYAVLTVSDTGLGMDQETKERIFDPFFTTKEVGKGTGLG
LSMVYGIVRQHEGFVTVDSEPGAGTTFRIYLPIVALTARHEEEAPPIVAKGNRETVLLAEDDKAVRKLSRHVLERNGYEV
IEAADGNDAVKKFAESVNKIDLVLLDVVMPGKNGQVAFEEMKRIQPAIKALFISGYTKDIIGSKGFLAEDINFIAKPVKP
DQLIARVQEALKS

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=265, Percent_Identity=29.811320754717, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=29.2682926829268, Blast_Score=109, Evalue=7e-25,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=32.9411764705882, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=30.2040816326531, Blast_Score=90, Evalue=5e-19,
Organism=Escherichia coli, GI87081816, Length=462, Percent_Identity=22.2943722943723, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI48994928, Length=336, Percent_Identity=27.0833333333333, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1786912, Length=269, Percent_Identity=27.1375464684015, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI145693157, Length=390, Percent_Identity=23.0769230769231, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 72487; Mature: 72355

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS50885 HAMP ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGMHDTLKQRHDSLGLRFFLLFASTIAVISISFTVLFYQQQRRILRENVTHEGQILARLL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AHNARLGVFAENGELLKDPVEGILQHDGVLFVSVISAAGTPIREQAHEKMLKTPERKIPN
HCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCC
WSVHFSDTRSSRVPHTFEEAELFEFWAPIVSIAPFQSTDALILGHEAQGKEKILGYARII
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHH
VDKHPLKRRLDTLLLICSTLTGGFLVLSTILTYLVVRRITNPLDRLTVGIKALEQGGAFV
HCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEE
PVKVERNHEIGRLANAFNHMAETLKKREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTAIVGFGTLLQRSLNKDNPYQIYVDQILNAADRATTLVKRLLAFGRKQVITPLPTDLN
HHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
GIIQSIEKLLARLVSEDVEFKVSLFNEPLVCHVDSGQIDQILMNLVTNARDAMPSGGTLT
HHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEE
LTTDATVLNENSFSSLEQCRPGRYAVLTVSDTGLGMDQETKERIFDPFFTTKEVGKGTGL
EEECCEEECCCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHCCCCCC
GLSMVYGIVRQHEGFVTVDSEPGAGTTFRIYLPIVALTARHEEEAPPIVAKGNRETVLLA
HHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEECCCCCEEEEE
EDDKAVRKLSRHVLERNGYEVIEAADGNDAVKKFAESVNKIDLVLLDVVMPGKNGQVAFE
CCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHH
EMKRIQPAIKALFISGYTKDIIGSKGFLAEDINFIAKPVKPDQLIARVQEALKS
HHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC
>Mature Secondary Structure 
GMHDTLKQRHDSLGLRFFLLFASTIAVISISFTVLFYQQQRRILRENVTHEGQILARLL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
AHNARLGVFAENGELLKDPVEGILQHDGVLFVSVISAAGTPIREQAHEKMLKTPERKIPN
HCCCCEEEEECCCCHHHHHHHHHHHCCCCHHHHHHHHCCCCHHHHHHHHHHCCCHHCCCC
WSVHFSDTRSSRVPHTFEEAELFEFWAPIVSIAPFQSTDALILGHEAQGKEKILGYARII
CEEEECCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHHH
VDKHPLKRRLDTLLLICSTLTGGFLVLSTILTYLVVRRITNPLDRLTVGIKALEQGGAFV
HCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCEE
PVKVERNHEIGRLANAFNHMAETLKKREAEKELLAEELRHAQKMEAIGTLAGGVAHDFNN
EEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILTAIVGFGTLLQRSLNKDNPYQIYVDQILNAADRATTLVKRLLAFGRKQVITPLPTDLN
HHHHHHHHHHHHHHHCCCCCCEEEEHHHHHCHHHHHHHHHHHHHHCCCCCCCCCCCCCHH
GIIQSIEKLLARLVSEDVEFKVSLFNEPLVCHVDSGQIDQILMNLVTNARDAMPSGGTLT
HHHHHHHHHHHHHHCCCCEEEEEECCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCEEE
LTTDATVLNENSFSSLEQCRPGRYAVLTVSDTGLGMDQETKERIFDPFFTTKEVGKGTGL
EEECCEEECCCCHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHCCCCHHHHHHCCCCCC
GLSMVYGIVRQHEGFVTVDSEPGAGTTFRIYLPIVALTARHEEEAPPIVAKGNRETVLLA
HHHHHHHHHHHCCCEEEECCCCCCCCEEEEEEHHHHHHHCCCCCCCCEEECCCCCEEEEE
EDDKAVRKLSRHVLERNGYEVIEAADGNDAVKKFAESVNKIDLVLLDVVMPGKNGQVAFE
CCCHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHH
EMKRIQPAIKALFISGYTKDIIGSKGFLAEDINFIAKPVKPDQLIARVQEALKS
HHHHHHHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA