| Definition | Geobacter sulfurreducens PCA chromosome, complete genome. |
|---|---|
| Accession | NC_002939 |
| Length | 3,814,139 |
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The map label for this gene is polC [H]
Identifier: 39996485
GI number: 39996485
Start: 1511698
End: 1512243
Strand: Direct
Name: polC [H]
Synonym: GSU1383
Alternate gene names: 39996485
Gene position: 1511698-1512243 (Clockwise)
Preceding gene: 39996484
Following gene: 39996486
Centisome position: 39.63
GC content: 63.37
Gene sequence:
>546_bases ATGAAAAATCACCATCTCCAGGCAGCGATCGATGTGGAAACCACCGGCCTTTTCCCGGGATATGGCGACAGGGTCGTCGA AGTGGCTGCCGTCCTTGTGGACGAGGGACAAATCGTCTCGGAATTCAGCAGCCTGATCAGGGTAACAAAGGCGATCCCCC GCCACGTATCCATGATTCACGGCATCACCAACGACATGCTCGCCGACCAGCCGCTGCCGGAAGAGGTCTACCCGGCTCTC GGAGATTTCATCGGCACGGCCCTGCTCGTGGCCCACAACGCCCGGTTCGATCTGGCATTCCTGCGGCACGAGTTCGGCCG GTTGGGATTGTCGCTGAACAGCCGGTCCGCCTGCACCCTGGAACTGGCCCGGCGCAGACTGCCGGAACTGACCGACCACC GCCTGGAAACCGTCTACCAGCACCTGTTCGGAGCCGTCCCCGAAGGGACCAGGTGCCACCGGGCGCTCGACGATGCGCGG CTCACGGCGCGGGTGTGGGGGGAGTTGGGGGGTGGGAAGGCTATGAAAAGTGGTGCTCTGCGGTAG
Upstream 100 bases:
>100_bases ACGGTATCGGGAAGTAACGATATGAAGGATAGTTCATGGTGAAAGACGCACAAAGATGCATCTTCCGGGAGGCACGCATG CACACAGGCGGTGACATGAC
Downstream 100 bases:
>100_bases TTGTGACTTGATTTGTCATAATGACATGATACTAACTGAACGCGATGATGGTGGCTTGCTTGGTTGCGTTGGAGGGGGAA ATGGAAAGTCTTACTGTCCC
Product: exonuclease
Products: NA
Alternate protein names: PolIII [H]
Number of amino acids: Translated: 181; Mature: 181
Protein sequence:
>181_residues MKNHHLQAAIDVETTGLFPGYGDRVVEVAAVLVDEGQIVSEFSSLIRVTKAIPRHVSMIHGITNDMLADQPLPEEVYPAL GDFIGTALLVAHNARFDLAFLRHEFGRLGLSLNSRSACTLELARRRLPELTDHRLETVYQHLFGAVPEGTRCHRALDDAR LTARVWGELGGGKAMKSGALR
Sequences:
>Translated_181_residues MKNHHLQAAIDVETTGLFPGYGDRVVEVAAVLVDEGQIVSEFSSLIRVTKAIPRHVSMIHGITNDMLADQPLPEEVYPAL GDFIGTALLVAHNARFDLAFLRHEFGRLGLSLNSRSACTLELARRRLPELTDHRLETVYQHLFGAVPEGTRCHRALDDAR LTARVWGELGGGKAMKSGALR >Mature_181_residues MKNHHLQAAIDVETTGLFPGYGDRVVEVAAVLVDEGQIVSEFSSLIRVTKAIPRHVSMIHGITNDMLADQPLPEEVYPAL GDFIGTALLVAHNARFDLAFLRHEFGRLGLSLNSRSACTLELARRRLPELTDHRLETVYQHLFGAVPEGTRCHRALDDAR LTARVWGELGGGKAMKSGALR
Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]
COG id: COG2176
COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 exonuclease domain [H]
Homologues:
Organism=Escherichia coli, GI1788149, Length=156, Percent_Identity=37.1794871794872, Blast_Score=78, Evalue=4e-16,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011708 - InterPro: IPR006054 - InterPro: IPR006055 - InterPro: IPR013520 - InterPro: IPR016027 - InterPro: IPR004013 - InterPro: IPR003141 - InterPro: IPR006308 - InterPro: IPR012337 [H]
Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]
EC number: =2.7.7.7 [H]
Molecular weight: Translated: 19917; Mature: 19917
Theoretical pI: Translated: 7.02; Mature: 7.02
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.2 %Met (Translated Protein) 3.3 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.2 %Met (Mature Protein) 3.3 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MKNHHLQAAIDVETTGLFPGYGDRVVEVAAVLVDEGQIVSEFSSLIRVTKAIPRHVSMIH CCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH GITNDMLADQPLPEEVYPALGDFIGTALLVAHNARFDLAFLRHEFGRLGLSLNSRSACTL HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHH ELARRRLPELTDHRLETVYQHLFGAVPEGTRCHRALDDARLTARVWGELGGGKAMKSGAL HHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC R C >Mature Secondary Structure MKNHHLQAAIDVETTGLFPGYGDRVVEVAAVLVDEGQIVSEFSSLIRVTKAIPRHVSMIH CCCCCEEEEEEEEECCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHH GITNDMLADQPLPEEVYPALGDFIGTALLVAHNARFDLAFLRHEFGRLGLSLNSRSACTL HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHHHH ELARRRLPELTDHRLETVYQHLFGAVPEGTRCHRALDDARLTARVWGELGGGKAMKSGAL HHHHHHCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCC R C
PDB accession: NA
Resolution: NA
Structure class: Alpha
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11792842 [H]