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The map label for this gene is 39996465

Identifier: 39996465

GI number: 39996465

Start: 1491977

End: 1493119

Strand: Direct

Name: 39996465

Synonym: GSU1363

Alternate gene names: NA

Gene position: 1491977-1493119 (Clockwise)

Preceding gene: 39996464

Following gene: 39996466

Centisome position: 39.12

GC content: 38.15

Gene sequence:

>1143_bases
ATGAGTATCTGGAGCCCGCTTTTATTTAATGCTGAAGGAAAGAAACAAGGGTATGATTGCCGTTATCTCCACAAGTTAAC
TGACCAAGGGAATAAACTCTCAGACAGTGGTTTGCCTGTAATTTTCACGCTCGCTCACCTGTGTGCGATGGCAGGTGTTT
CCTTTTCTCTCATTCACTCCTGTGTGTCCAGGAAATACGACCCATATAGAAGCTTTACAATTAAAAAGAGGTCGGGAGGG
TATCGCCAAATTGTGGTGCCTGAACCTGAGTTAATGCATCTCCAGAGATGGATTAATGAGTTTATATTGAAGCGGGCAAA
GGTGCATTCTTGTGCTGCTGCATATATTTCAGGCTCCGATATAAAAATGAATGCTTCAAAGCATCTCGGTGCAAACTGGC
TAATAAAGTTAGATATACAGAGATTTTTCGAGTCTATATCAGAACTGCAAGTTTATTATATCTTCCATAGACTTGGGTAT
CCAAAATTATTGTCGTTTGAAATGGCCAGAATCTGTACCAGAGTAGACACCCAAAGCAATAGACATTTTAGACCAAGATG
GAATAACAGAATCCATCACTTCGAAATCCTTGAGTACTGTGATTCTAGGGTTGGTTATTTACCACAAGGTGCTCCTACTA
GTCCGAGTTTGTCCAATTTAACCTGCCGAAAACTTGATAAAGAAATTTACGACCTTAGTTGCCGTTCTGATTGCCGATAT
ACTAGATATGCAGATGACTTCGCCTTTTCTTTTATAGATCTTGATAGGGAAAAAGCCTCAAATTTTGTAAATCAAGTCAG
TCGAATCATATCATCTTACGGTTTTAGAAAGAATGCTCGAAAAACAAAGATCATACCCCCTGGATCAAAAAAAATTATTA
CCGGGCTTGTTTTGGGTAATGGGAAAGTGCATCTTCAGAAAGAATTAAAGGATTACATAAGACAAAATATATACTTTGCA
ACTAAATATGGTGTAGATGAACACTGTAAAAAACGTGGATTCGTCTCAATAGATGGATTTTATAATCATCTGGAAGGAAT
TGTTAATTTTGCACTATTTATTGAACCAGATTTTGGAGAAAAAGCCTTTGAGGAGTTTCGTGCAATTAAGTGGCCATCTT
TAATAGTGGGGCTTCATGCTTAG

Upstream 100 bases:

>100_bases
AATAGCACATGAATGAACAAGGATATTAATGGCAAACGCTTACGTTCGTATGCCTTACTACGTTCGCCATTAATGTCCTC
GCTTCGCGAGGTTGAAGTAG

Downstream 100 bases:

>100_bases
AACAAGTGGTCGTGTCGCAACCATTTACAAGTTCATAATATTTTGAGAACCATGACCTTTCTCCCCACCTCCCTCAAATT
CTTCTCCTCCCTCTCCCGCG

Product: RNA-directed DNA polymerase

Products: NA

Alternate protein names: Mx162-RT; Reverse transcriptase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MSIWSPLLFNAEGKKQGYDCRYLHKLTDQGNKLSDSGLPVIFTLAHLCAMAGVSFSLIHSCVSRKYDPYRSFTIKKRSGG
YRQIVVPEPELMHLQRWINEFILKRAKVHSCAAAYISGSDIKMNASKHLGANWLIKLDIQRFFESISELQVYYIFHRLGY
PKLLSFEMARICTRVDTQSNRHFRPRWNNRIHHFEILEYCDSRVGYLPQGAPTSPSLSNLTCRKLDKEIYDLSCRSDCRY
TRYADDFAFSFIDLDREKASNFVNQVSRIISSYGFRKNARKTKIIPPGSKKIITGLVLGNGKVHLQKELKDYIRQNIYFA
TKYGVDEHCKKRGFVSIDGFYNHLEGIVNFALFIEPDFGEKAFEEFRAIKWPSLIVGLHA

Sequences:

>Translated_380_residues
MSIWSPLLFNAEGKKQGYDCRYLHKLTDQGNKLSDSGLPVIFTLAHLCAMAGVSFSLIHSCVSRKYDPYRSFTIKKRSGG
YRQIVVPEPELMHLQRWINEFILKRAKVHSCAAAYISGSDIKMNASKHLGANWLIKLDIQRFFESISELQVYYIFHRLGY
PKLLSFEMARICTRVDTQSNRHFRPRWNNRIHHFEILEYCDSRVGYLPQGAPTSPSLSNLTCRKLDKEIYDLSCRSDCRY
TRYADDFAFSFIDLDREKASNFVNQVSRIISSYGFRKNARKTKIIPPGSKKIITGLVLGNGKVHLQKELKDYIRQNIYFA
TKYGVDEHCKKRGFVSIDGFYNHLEGIVNFALFIEPDFGEKAFEEFRAIKWPSLIVGLHA
>Mature_379_residues
SIWSPLLFNAEGKKQGYDCRYLHKLTDQGNKLSDSGLPVIFTLAHLCAMAGVSFSLIHSCVSRKYDPYRSFTIKKRSGGY
RQIVVPEPELMHLQRWINEFILKRAKVHSCAAAYISGSDIKMNASKHLGANWLIKLDIQRFFESISELQVYYIFHRLGYP
KLLSFEMARICTRVDTQSNRHFRPRWNNRIHHFEILEYCDSRVGYLPQGAPTSPSLSNLTCRKLDKEIYDLSCRSDCRYT
RYADDFAFSFIDLDREKASNFVNQVSRIISSYGFRKNARKTKIIPPGSKKIITGLVLGNGKVHLQKELKDYIRQNIYFAT
KYGVDEHCKKRGFVSIDGFYNHLEGIVNFALFIEPDFGEKAFEEFRAIKWPSLIVGLHA

Specific function: Participates in the synthesis of a msDNA (a branched RNA linked by a 2',5'-phosphodiester linkage to a single-stranded DNA) of unknown function. The retron transcript serves as primer and template to the reaction, and codes for the RT [H]

COG id: COG3344

COG function: function code L; Retron-type reverse transcriptase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 reverse transcriptase domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000123
- InterPro:   IPR000477 [H]

Pfam domain/function: PF00078 RVT_1 [H]

EC number: =2.7.7.49 [H]

Molecular weight: Translated: 43973; Mature: 43842

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: PS50878 RT_POL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIWSPLLFNAEGKKQGYDCRYLHKLTDQGNKLSDSGLPVIFTLAHLCAMAGVSFSLIHS
CCCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
CVSRKYDPYRSFTIKKRSGGYRQIVVPEPELMHLQRWINEFILKRAKVHSCAAAYISGSD
HHHCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
IKMNASKHLGANWLIKLDIQRFFESISELQVYYIFHRLGYPKLLSFEMARICTRVDTQSN
EEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
RHFRPRWNNRIHHFEILEYCDSRVGYLPQGAPTSPSLSNLTCRKLDKEIYDLSCRSDCRY
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
TRYADDFAFSFIDLDREKASNFVNQVSRIISSYGFRKNARKTKIIPPGSKKIITGLVLGN
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECC
GKVHLQKELKDYIRQNIYFATKYGVDEHCKKRGFVSIDGFYNHLEGIVNFALFIEPDFGE
CCEEHHHHHHHHHHHCEEEEEECCCHHHHHHCCCEEEHHHHHHHHHHHHEEEEECCCCCH
KAFEEFRAIKWPSLIVGLHA
HHHHHHHHCCCCHHEEEECC
>Mature Secondary Structure 
SIWSPLLFNAEGKKQGYDCRYLHKLTDQGNKLSDSGLPVIFTLAHLCAMAGVSFSLIHS
CCCCCCEECCCCCCCCCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCHHHHHHH
CVSRKYDPYRSFTIKKRSGGYRQIVVPEPELMHLQRWINEFILKRAKVHSCAAAYISGSD
HHHCCCCCCCCEEEEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCC
IKMNASKHLGANWLIKLDIQRFFESISELQVYYIFHRLGYPKLLSFEMARICTRVDTQSN
EEECCCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCC
RHFRPRWNNRIHHFEILEYCDSRVGYLPQGAPTSPSLSNLTCRKLDKEIYDLSCRSDCRY
CCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCC
TRYADDFAFSFIDLDREKASNFVNQVSRIISSYGFRKNARKTKIIPPGSKKIITGLVLGN
CCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCEEEEEEEECC
GKVHLQKELKDYIRQNIYFATKYGVDEHCKKRGFVSIDGFYNHLEGIVNFALFIEPDFGE
CCEEHHHHHHHHHHHCEEEEEECCCHHHHHHCCCEEEHHHHHHHHHHHHEEEEECCCCCH
KAFEEFRAIKWPSLIVGLHA
HHHHHHHHCCCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2465092; 2465091 [H]