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The map label for this gene is degU [H]

Identifier: 39996395

GI number: 39996395

Start: 1409987

End: 1410637

Strand: Direct

Name: degU [H]

Synonym: GSU1293

Alternate gene names: 39996395

Gene position: 1409987-1410637 (Clockwise)

Preceding gene: 39996394

Following gene: 39996396

Centisome position: 36.97

GC content: 58.22

Gene sequence:

>651_bases
GTGGGGATACGGGTTGTAATTGTTGACGACCATAAGATCATGCGCGAGGGGCTCAAGTCGCTTCTTTCGATGGAAAAGGA
TATCCAGGTGGTCGGTGAGGCCGATAACGGCCGGGCCGCCACCCAGTGCGTGAAGGATCTCGACCCGGACATAGTCCTCA
TGGATCTCACCATGCCGGAGATGAACGGCATTGATGCGACAAGGCGCATAGCCGCAGATTATCCCTCGGTCAGGGTTCTC
GCCCTTTCCATGCATTCGGATCGTCGCTTCATCGAAGAGGCGCTTTCTGCGGGCGCCCAAGGGTTTCTCCTCAAAGACTG
CGCTTTTGACGAACTGGTCAATGCCATCCACGAAGTGGTTGCCGACCGGTTTTACCTCAGTCCCCGCATTACCGGCGTCG
TGATCAAGGACTATCTCGGTCGACGGGGCCGGCCCGAGTCCGCTTCCTCGATTCGCCTCACCCCCCGCGAACGGGAAGTG
CTTCAGCTCATTGCCGAGGGCAAGAATACCAAGGAAGTGGCCTTTGCCCTCGATGTCAGCGTCAAGACCGTGGAGTCCCA
GCGTATGCAGATCATGCGCAAGCTCAAGACCAACAGTATCGCCGACCTGACCAAGTTCGCCATCCGCGAGGGACTCACCA
CCCTCGACTGA

Upstream 100 bases:

>100_bases
CGTCGAATGGCACTGTTTGTCGGCCGGGAACGGCTTTGAGTCGGGGTATGGGACGAAAACCGTTGGTTGTGGACAGGTTC
TGAGGGAGCGAGGTTGCCGA

Downstream 100 bases:

>100_bases
ACGCTGGTCTTCCTGTCCCGTCAACGACGCTCCGAGCCGGTCAGCTGCAGGCTACGCCATTGCCGCGCCGGCGACAATTC
CTCCGTTCCTTTCTATTTCA

Product: LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 216; Mature: 215

Protein sequence:

>216_residues
MGIRVVIVDDHKIMREGLKSLLSMEKDIQVVGEADNGRAATQCVKDLDPDIVLMDLTMPEMNGIDATRRIAADYPSVRVL
ALSMHSDRRFIEEALSAGAQGFLLKDCAFDELVNAIHEVVADRFYLSPRITGVVIKDYLGRRGRPESASSIRLTPREREV
LQLIAEGKNTKEVAFALDVSVKTVESQRMQIMRKLKTNSIADLTKFAIREGLTTLD

Sequences:

>Translated_216_residues
MGIRVVIVDDHKIMREGLKSLLSMEKDIQVVGEADNGRAATQCVKDLDPDIVLMDLTMPEMNGIDATRRIAADYPSVRVL
ALSMHSDRRFIEEALSAGAQGFLLKDCAFDELVNAIHEVVADRFYLSPRITGVVIKDYLGRRGRPESASSIRLTPREREV
LQLIAEGKNTKEVAFALDVSVKTVESQRMQIMRKLKTNSIADLTKFAIREGLTTLD
>Mature_215_residues
GIRVVIVDDHKIMREGLKSLLSMEKDIQVVGEADNGRAATQCVKDLDPDIVLMDLTMPEMNGIDATRRIAADYPSVRVLA
LSMHSDRRFIEEALSAGAQGFLLKDCAFDELVNAIHEVVADRFYLSPRITGVVIKDYLGRRGRPESASSIRLTPREREVL
QLIAEGKNTKEVAFALDVSVKTVESQRMQIMRKLKTNSIADLTKFAIREGLTTLD

Specific function: Regulating factor for the production of extracellular proteases. The N-terminal region acts as an inhibitor, whereas the C-terminal region carries enhancing activity [H]

COG id: COG2197

COG function: function code TK; Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788222, Length=216, Percent_Identity=33.7962962962963, Blast_Score=127, Evalue=6e-31,
Organism=Escherichia coli, GI1790102, Length=203, Percent_Identity=35.4679802955665, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1787473, Length=181, Percent_Identity=38.121546961326, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1788521, Length=200, Percent_Identity=33, Blast_Score=98, Evalue=4e-22,
Organism=Escherichia coli, GI1788546, Length=209, Percent_Identity=29.6650717703349, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788712, Length=212, Percent_Identity=28.3018867924528, Blast_Score=87, Evalue=6e-19,
Organism=Escherichia coli, GI1786747, Length=203, Percent_Identity=28.5714285714286, Blast_Score=86, Evalue=1e-18,
Organism=Escherichia coli, GI1788550, Length=109, Percent_Identity=33.0275229357798, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 24088; Mature: 23957

Theoretical pI: Translated: 6.29; Mature: 6.29

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGIRVVIVDDHKIMREGLKSLLSMEKDIQVVGEADNGRAATQCVKDLDPDIVLMDLTMPE
CCEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCEEEEEECCCC
MNGIDATRRIAADYPSVRVLALSMHSDRRFIEEALSAGAQGFLLKDCAFDELVNAIHEVV
CCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
ADRFYLSPRITGVVIKDYLGRRGRPESASSIRLTPREREVLQLIAEGKNTKEVAFALDVS
HHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCEEEEEEECH
VKTVESQRMQIMRKLKTNSIADLTKFAIREGLTTLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GIRVVIVDDHKIMREGLKSLLSMEKDIQVVGEADNGRAATQCVKDLDPDIVLMDLTMPE
CEEEEEECCHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHCCCCEEEEEECCCC
MNGIDATRRIAADYPSVRVLALSMHSDRRFIEEALSAGAQGFLLKDCAFDELVNAIHEVV
CCCCCHHHHHHCCCCCEEEEEEECCHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHH
ADRFYLSPRITGVVIKDYLGRRGRPESASSIRLTPREREVLQLIAEGKNTKEVAFALDVS
HHHHHCCCCHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHHHHHHCCCCCCEEEEEEECH
VKTVESQRMQIMRKLKTNSIADLTKFAIREGLTTLD
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7765823 [H]