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The map label for this gene is cheA-1 [H]

Identifier: 39996392

GI number: 39996392

Start: 1405859

End: 1407964

Strand: Direct

Name: cheA-1 [H]

Synonym: GSU1290

Alternate gene names: 39996392

Gene position: 1405859-1407964 (Clockwise)

Preceding gene: 39996391

Following gene: 39996393

Centisome position: 36.86

GC content: 62.16

Gene sequence:

>2106_bases
ATGGACGCCCATCGGCAGGCTTACAGGGAAGAGGCCTACGAGCTGCTCGCCGAACTGGAGAGCTCGCTTCTGGAACTGGA
AGAGAACCCGGAGGACTTGGACCTCATCGGCCGCGTGTTTCGCGCCATGCACACCATTAAAGGGTCCGGTGCCATGTTCG
GCTTCGAGGACATCGCCACGTTCACCCACGAAGTGGAGACGGTCTTCGACAAGGTCCGCAACGGCCAGATGACGGTGACC
CGGGAACTGGTGAACCTGACTCTCAGGGCCCGGGACCTCATCAAGGGAATGCTTGATGCCTCGGAGGGAGGCGACCCCGT
GGAGGGGCGCGAGGCAGAAGAGGTGATAGCCGGTCTGCGGGCACTGGTCCCCGCTCCCGAGGTGAGAGATCCCCTGCCCA
TGGAATCGGTTCACGCCCCGCTCGACACCGAGGGAAAGGGGGATGCGGCGGTGACCTACCGCATCCGGTTCATTCCCACC
CCGGAAATAACCGTCAACGGCACCAACCCGCTCCTTCTGCTGGCCGAGCTGCGTCAGCTCGGTGCCTGCCGGGTCGTAGC
CCAGATGGAGCGCGTGCCGACACTGGAAGAGTGCAATCCCGAGCTCTGCTACGTGTATTGGGACGTGATTCTGACCAGCA
GGCGAGGGGTCGATGCCATCCGCGACGTGTTCATCTTCATCGAGGATGATTGCGAACTGAAGATCGACACCATCGACGAC
GGGGGCGTCCTCGACACCGATTCCGACTACAAGAAACTCGGCATCATCCTGGCCGAGCGCGGGGACCTGACACGGCAGGA
CATGGAAGCGATCCTCGCCCGCCAGAAGCGTTTCGGCGAACTGCTGGTGGAGCAGGGCATCCTGCAACCCGAAAAGGTCG
AGTCGGCCCTTATCGAGCAGCAGCACGTGAAGGAGGTCCGCAAGGAACGCCAGGCCCAGGAAAGCGCTTCCAGTATCCGG
GTGCCGGCCGAGAAGCTCGACATACTCGTAAATCTCGTGGGTGAGCTCGTTACGGTGCAGGCCCGGCTCTCGCAGACCGC
CGCCGGCCGCGACGATGCCCTCCTCGTTACCATCGCCGAAGAAGTGGAGCGCCTTACCAACGAACTGCGCGACACAGCCC
TCAACATCCGGATGCTCCCAATCGGTACAACCTTCAGCAAGTTCAAGCGGCTGGTCCGCGACCTGTCGGTGGAACTGGGC
AAGGATATCGAGCTGACCACCACCGGCGCCGAAACCGAGCTGGACAAGACGGTCATCGAAAAACTGAACGACCCCTTGGT
CCACCTGATCCGCAACTCCATCGACCACGGCATTGAGATGCCCGAGGCCCGCGAGGCCGCCGGCAAACCCCGCCAGGGGA
CCGTGCATCTTGCCGCGGTTCACTCGGGAGACAGCGTGCTCATCACTATCACCGACGATGGAGCCGGCCTCGACAAGGAG
GCAATCCGGGCCAAGGGTGTCGAGCGCGGCCTCATTACAGCCAGTGCCGAGCTGACGGACAAGGAGATCTACAACCTGAT
CTTCGCGCCCGGCTTCTCCACGGCCAAGAAAGTCACCAGCGTTTCGGGGCGCGGCGTCGGCATGGACGTGGTGAAGAAGG
CCATCGATGCCCTGCGCGGCACCATCGATATCGCCAGTGAACGGGGGAAGGGGAGCACCATCACCATCAAACTTCCGCTG
ACCCTGGCGATCATCGAAAGCCTGCTGGTCAAGATCGGTACCGACTGCTTCGTTATGCCGCTGTCCATCGTGGAGGAGTG
CATCGAGCTTACCCGCGAGGACGTGGCCAACGCCCATGGCCGCAACCTGGCGAATGTCCGTGACCAGATAATCCCCTATG
TCCCCTTGCGCGAACGCTTCCGCATCCAGGGGGAACCTCCGGAAATCGAGCAGATCGTGATCACTTCCATCCAGGGGAGC
CGGATCGGCTTCGTTGTCGACGATGTGATCGGCGAACACCAGACCGTCATAAAGTCGCTGGGCAAGATGTACAAGGATGT
GAAGGGGCTTTCGGGCGCAACTATCCTCGGTGACGGCTCCGTGGCTCTCATCCTGGATGTCCCCCATCTGGTGCGCGAGG
TGGAACGGGAACAGGTCGCCCGGTAG

Upstream 100 bases:

>100_bases
GCCGAAAGCAGGAAGGCAAGGCCGCCGGTGCCACCGGCTGGATCGTCAAACCCTTCAAGCCTGAGCAGCTGGTGGCGGTG
GTCAAGAAGGTGCTCGGCTA

Downstream 100 bases:

>100_bases
AATGTGCTCTGCCGGCGCCTGCAATGCACTGTTAACGGCAATGCCGCGGTAAAACGCGGCATTTTTTTCCTGCGTGGGGC
AGCAGGGTAGGGACGGGCAC

Product: chemotaxis protein CheA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 701; Mature: 701

Protein sequence:

>701_residues
MDAHRQAYREEAYELLAELESSLLELEENPEDLDLIGRVFRAMHTIKGSGAMFGFEDIATFTHEVETVFDKVRNGQMTVT
RELVNLTLRARDLIKGMLDASEGGDPVEGREAEEVIAGLRALVPAPEVRDPLPMESVHAPLDTEGKGDAAVTYRIRFIPT
PEITVNGTNPLLLLAELRQLGACRVVAQMERVPTLEECNPELCYVYWDVILTSRRGVDAIRDVFIFIEDDCELKIDTIDD
GGVLDTDSDYKKLGIILAERGDLTRQDMEAILARQKRFGELLVEQGILQPEKVESALIEQQHVKEVRKERQAQESASSIR
VPAEKLDILVNLVGELVTVQARLSQTAAGRDDALLVTIAEEVERLTNELRDTALNIRMLPIGTTFSKFKRLVRDLSVELG
KDIELTTTGAETELDKTVIEKLNDPLVHLIRNSIDHGIEMPEAREAAGKPRQGTVHLAAVHSGDSVLITITDDGAGLDKE
AIRAKGVERGLITASAELTDKEIYNLIFAPGFSTAKKVTSVSGRGVGMDVVKKAIDALRGTIDIASERGKGSTITIKLPL
TLAIIESLLVKIGTDCFVMPLSIVEECIELTREDVANAHGRNLANVRDQIIPYVPLRERFRIQGEPPEIEQIVITSIQGS
RIGFVVDDVIGEHQTVIKSLGKMYKDVKGLSGATILGDGSVALILDVPHLVREVEREQVAR

Sequences:

>Translated_701_residues
MDAHRQAYREEAYELLAELESSLLELEENPEDLDLIGRVFRAMHTIKGSGAMFGFEDIATFTHEVETVFDKVRNGQMTVT
RELVNLTLRARDLIKGMLDASEGGDPVEGREAEEVIAGLRALVPAPEVRDPLPMESVHAPLDTEGKGDAAVTYRIRFIPT
PEITVNGTNPLLLLAELRQLGACRVVAQMERVPTLEECNPELCYVYWDVILTSRRGVDAIRDVFIFIEDDCELKIDTIDD
GGVLDTDSDYKKLGIILAERGDLTRQDMEAILARQKRFGELLVEQGILQPEKVESALIEQQHVKEVRKERQAQESASSIR
VPAEKLDILVNLVGELVTVQARLSQTAAGRDDALLVTIAEEVERLTNELRDTALNIRMLPIGTTFSKFKRLVRDLSVELG
KDIELTTTGAETELDKTVIEKLNDPLVHLIRNSIDHGIEMPEAREAAGKPRQGTVHLAAVHSGDSVLITITDDGAGLDKE
AIRAKGVERGLITASAELTDKEIYNLIFAPGFSTAKKVTSVSGRGVGMDVVKKAIDALRGTIDIASERGKGSTITIKLPL
TLAIIESLLVKIGTDCFVMPLSIVEECIELTREDVANAHGRNLANVRDQIIPYVPLRERFRIQGEPPEIEQIVITSIQGS
RIGFVVDDVIGEHQTVIKSLGKMYKDVKGLSGATILGDGSVALILDVPHLVREVEREQVAR
>Mature_701_residues
MDAHRQAYREEAYELLAELESSLLELEENPEDLDLIGRVFRAMHTIKGSGAMFGFEDIATFTHEVETVFDKVRNGQMTVT
RELVNLTLRARDLIKGMLDASEGGDPVEGREAEEVIAGLRALVPAPEVRDPLPMESVHAPLDTEGKGDAAVTYRIRFIPT
PEITVNGTNPLLLLAELRQLGACRVVAQMERVPTLEECNPELCYVYWDVILTSRRGVDAIRDVFIFIEDDCELKIDTIDD
GGVLDTDSDYKKLGIILAERGDLTRQDMEAILARQKRFGELLVEQGILQPEKVESALIEQQHVKEVRKERQAQESASSIR
VPAEKLDILVNLVGELVTVQARLSQTAAGRDDALLVTIAEEVERLTNELRDTALNIRMLPIGTTFSKFKRLVRDLSVELG
KDIELTTTGAETELDKTVIEKLNDPLVHLIRNSIDHGIEMPEAREAAGKPRQGTVHLAAVHSGDSVLITITDDGAGLDKE
AIRAKGVERGLITASAELTDKEIYNLIFAPGFSTAKKVTSVSGRGVGMDVVKKAIDALRGTIDIASERGKGSTITIKLPL
TLAIIESLLVKIGTDCFVMPLSIVEECIELTREDVANAHGRNLANVRDQIIPYVPLRERFRIQGEPPEIEQIVITSIQGS
RIGFVVDDVIGEHQTVIKSLGKMYKDVKGLSGATILGDGSVALILDVPHLVREVEREQVAR

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=450, Percent_Identity=44.6666666666667, Blast_Score=346, Evalue=3e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 77219; Mature: 77219

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAHRQAYREEAYELLAELESSLLELEENPEDLDLIGRVFRAMHTIKGSGAMFGFEDIAT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FTHEVETVFDKVRNGQMTVTRELVNLTLRARDLIKGMLDASEGGDPVEGREAEEVIAGLR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ALVPAPEVRDPLPMESVHAPLDTEGKGDAAVTYRIRFIPTPEITVNGTNPLLLLAELRQL
HHCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCHHHHHHHHHHH
GACRVVAQMERVPTLEECNPELCYVYWDVILTSRRGVDAIRDVFIFIEDDCELKIDTIDD
HHHHHHHHHHHCCCHHHCCCCEEEEEHHHHHHCCCCHHHHHHEEEEEECCCEEEEEECCC
GGVLDTDSDYKKLGIILAERGDLTRQDMEAILARQKRFGELLVEQGILQPEKVESALIEQ
CCCCCCCCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QHVKEVRKERQAQESASSIRVPAEKLDILVNLVGELVTVQARLSQTAAGRDDALLVTIAE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHH
EVERLTNELRDTALNIRMLPIGTTFSKFKRLVRDLSVELGKDIELTTTGAETELDKTVIE
HHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
KLNDPLVHLIRNSIDHGIEMPEAREAAGKPRQGTVHLAAVHSGDSVLITITDDGAGLDKE
HCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHH
AIRAKGVERGLITASAELTDKEIYNLIFAPGFSTAKKVTSVSGRGVGMDVVKKAIDALRG
HHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TIDIASERGKGSTITIKLPLTLAIIESLLVKIGTDCFVMPLSIVEECIELTREDVANAHG
HHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCC
RNLANVRDQIIPYVPLRERFRIQGEPPEIEQIVITSIQGSRIGFVVDDVIGEHQTVIKSL
CCHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCEEHHHHHCCHHHHHHHH
GKMYKDVKGLSGATILGDGSVALILDVPHLVREVEREQVAR
HHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHCC
>Mature Secondary Structure
MDAHRQAYREEAYELLAELESSLLELEENPEDLDLIGRVFRAMHTIKGSGAMFGFEDIAT
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHH
FTHEVETVFDKVRNGQMTVTRELVNLTLRARDLIKGMLDASEGGDPVEGREAEEVIAGLR
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
ALVPAPEVRDPLPMESVHAPLDTEGKGDAAVTYRIRFIPTPEITVNGTNPLLLLAELRQL
HHCCCCCCCCCCCHHHHCCCCCCCCCCCEEEEEEEEEECCCCEEECCCCHHHHHHHHHHH
GACRVVAQMERVPTLEECNPELCYVYWDVILTSRRGVDAIRDVFIFIEDDCELKIDTIDD
HHHHHHHHHHHCCCHHHCCCCEEEEEHHHHHHCCCCHHHHHHEEEEEECCCEEEEEECCC
GGVLDTDSDYKKLGIILAERGDLTRQDMEAILARQKRFGELLVEQGILQPEKVESALIEQ
CCCCCCCCCHHHHEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
QHVKEVRKERQAQESASSIRVPAEKLDILVNLVGELVTVQARLSQTAAGRDDALLVTIAE
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEHHH
EVERLTNELRDTALNIRMLPIGTTFSKFKRLVRDLSVELGKDIELTTTGAETELDKTVIE
HHHHHHHHHHHHHEEEEEEECCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHH
KLNDPLVHLIRNSIDHGIEMPEAREAAGKPRQGTVHLAAVHSGDSVLITITDDGAGLDKE
HCCCHHHHHHHHHHHCCCCCCCHHHHCCCCCCCEEEEEEEECCCEEEEEEECCCCCCCHH
AIRAKGVERGLITASAELTDKEIYNLIFAPGFSTAKKVTSVSGRGVGMDVVKKAIDALRG
HHHHCCCCCCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHH
TIDIASERGKGSTITIKLPLTLAIIESLLVKIGTDCFVMPLSIVEECIELTREDVANAHG
HHHHHCCCCCCCEEEEEECHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHCCC
RNLANVRDQIIPYVPLRERFRIQGEPPEIEQIVITSIQGSRIGFVVDDVIGEHQTVIKSL
CCHHHHHHHHCCCCCCHHHHCCCCCCCCCCEEEEEECCCCCCCEEHHHHHCCHHHHHHHH
GKMYKDVKGLSGATILGDGSVALILDVPHLVREVEREQVAR
HHHHHHHCCCCCCEEECCCCEEEEEECHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7623670; 11481430 [H]