Click here to switch to the map view.

The map label for this gene is bvgS [H]

Identifier: 39996387

GI number: 39996387

Start: 1400351

End: 1402669

Strand: Direct

Name: bvgS [H]

Synonym: GSU1285

Alternate gene names: 39996387

Gene position: 1400351-1402669 (Clockwise)

Preceding gene: 39996386

Following gene: 39996388

Centisome position: 36.71

GC content: 62.4

Gene sequence:

>2319_bases
ATGGTCGGCAGTCTGGTAACTTATCTGAAAAAGTGCGCTGCATCGGTGCTGGGAGCACCGTACACGCTGCTTTGCCGACT
GCTGCCCCGAATCACGGCGGACCTTCGCTACGGGTCCGGCTATCGAGCATTATTCGAGCACGCGATTGACGGCATCTTCA
TCATGGATGCTGAGGGACACTATCTTGACGTCAATCCCGCCATCTGTTCCGCAATCGGCTACACCAGGGATGAATTCCTT
GCTCTGGATTGGGGCGTGCTCAGCAGGGGAGTCGATTCCGGGTGGGCCGCGGCATCGCTGGCGCGAATAGTCGGCGGTGA
GCCCCTGCGGGAAGAGCGGACCGTCTGGACCCGCAACGGAGATCAGCTGACGGTGGAGCTTTCGGCGCACCTGCTGCCGG
ACGGCAAGATTCTCGGGATTGCGCGGGATGTCTCCGAACGGAAGCGGATGGAGGAGTCTCTGCGGTCCACCAGCGAATTC
CTCGATACGATACTCGATGAGGCTCCGCTGCCGATCTACATTACATCCGTGGACGGAACGCTCCGGCTTGCCAACAATGC
CTGGGAGCGCGAGACGGGCATCCCTCGCAACGCAGCCGTCGGTCGTCGCCTGAATGAACTATTCCCGGCTGCAATGTGTG
ACCAGTTCTCTGAAATCAATCGCCGCGTCGTCGAATCAAATGCCACCGCCGTCCAAGATGAATTCCTCGATTTCGGTGCG
GGCGTGCGAGTGTTTCACACTATCAAGTTTCCCCTCAGGGACGCCGCCGGGGGAGTGGTCGATGTCGGTGGTATATCGAT
CGACATCACCGACCGTTCGAAGATGGAGGGCGAACTGAGGGCCGCCCATGCCGCCGCCGTTGACTCTTCCCGGGCCAAGA
TCGATTTTCTGGCTAACATGAGCCACGAGATCCGGACTCCCATGAACGGCGTGATCGGTACGCTGGAGCTCCTGAGGGAA
ACCGACCTGGACCCCAGGCAGCGTGAGTACGCCGAGATTGCCCGCGAGTCGGCGGAAAGCATGCTGGCGGTGATAAACAT
GGTCCTCGACTACTCGAAGATCGAATCACACCAGCTGGTACTCGAAGCGGTCCCCTTCGCCATCCGGGAGGCTGTCGAAC
GGGCCGTCAAACCGTTCAGGGCTGTTGCTGCGCGCAAGGGGGTTATGGTTGCGGCCGATGTGCCGCCTCACGTGCCGGAG
ACGGTGGTGGGTGATCCGGTTCGCTTCTCGCAAATCGTGGCAAACCTGGTGGGCAATGCCGTGAAGTTCACCGAACAGGG
GGCAATTACCGTTCAGTTGGGAGCCGCCGCCGTCGACGACTGCCGGATTGACGTTTCCTGCTCCGTCGGCGATACCGGTG
CCGGCATTTCTCCGGAAAAGTTCGACACGATCTTCGATCCGTTTGTTCAGGCCGACGGCTCCACCACCCGCATCCACGGG
GGAACCGGCCTGGGCCTCGCCATCGTCCGCCGCCTGGTGGAGGCCATGGACGGGGTGATTTCCGTTGCGAGCGAACCCGG
CATGGGGAGTACCTTTTCATTCCGGGTCCGTCTGCGTGGTGCGCCGGATGACATCGCCTCCCCGCCGCCTGCAACCGGCT
GGGCGGTAGCGGAAAAATCTGTTGCGGTCCGGCCCCTGTCGGTGCTTCTGGTCGATGATAGCGCGGTCAGTCGCAAAGTT
GTTTCTCTGCTGCTTGAAAGCGACGGCCACAGGGTTACCTTTGCCGGAGACGGCGTCGAGGCCCTGGCCGCGATCGGCCG
GGAAGCTTTTGATCTCGTGTTGATGGATGTTCAAATGCCGGTGATGGACGGTTTTGAAGCCATGAGGGCCATCCGTGCGG
GCGAAGCGGCCGGTGGGGCACGGCTTCCGATCATTGCCCTGACGGCCCGCGCCCTGGCAGGCGACCGGGAACTCTGCCTT
GAGGCGGGAGCCGACGACTACCTGGCCAAGCCGGTTAACTTCAGTGAATTAAGGCGGGTCATCAGCCGGCATTGCTGCCG
TGAGAGCAAGCCGTCCGCACTGTCTGCGGAGAACAGGCCGGATGCTGCCGGCGCGACTCCGCCGGCAGGGACGTTCGGTG
AACTGATGGACGAACTGGGTGCGTCCGTGGGGGATCGGGACGAGGATGCGGTGGAGCGCTGCACGCGCATGCTGAAGCGG
GCAGCCTCCCATCTCGGCAGGACCAGGCTCGTTGACGAAATATTTCGACTGCAGCTCGCCTCGCGGCGGGGAGATTGGGA
ACGGGCGGACGAGCTGCTCGGTGTTGTGGCTGAACTGCTTCCGACAACGGCGGGCGCATGCGGTCCGCCGGAGGCGTGA

Upstream 100 bases:

>100_bases
TTTTCAGAAAACTCTCAACTATTCGGAGCGGGGGACGATAAGCTGACGTAGCAGTCTATAAAAACGCTCTGAGCACCATC
CCGGCTTTCGGAGAGCACTA

Downstream 100 bases:

>100_bases
GACGGGTTAATGAACTGATGTGGAAAGGAGATGTCGATGAAGACGCTTATTGTTGAGGACGATTTCATCTCGCGCAAAAT
CATGAAGGAGCTTCTCACCT

Product: sensory box sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 772; Mature: 772

Protein sequence:

>772_residues
MVGSLVTYLKKCAASVLGAPYTLLCRLLPRITADLRYGSGYRALFEHAIDGIFIMDAEGHYLDVNPAICSAIGYTRDEFL
ALDWGVLSRGVDSGWAAASLARIVGGEPLREERTVWTRNGDQLTVELSAHLLPDGKILGIARDVSERKRMEESLRSTSEF
LDTILDEAPLPIYITSVDGTLRLANNAWERETGIPRNAAVGRRLNELFPAAMCDQFSEINRRVVESNATAVQDEFLDFGA
GVRVFHTIKFPLRDAAGGVVDVGGISIDITDRSKMEGELRAAHAAAVDSSRAKIDFLANMSHEIRTPMNGVIGTLELLRE
TDLDPRQREYAEIARESAESMLAVINMVLDYSKIESHQLVLEAVPFAIREAVERAVKPFRAVAARKGVMVAADVPPHVPE
TVVGDPVRFSQIVANLVGNAVKFTEQGAITVQLGAAAVDDCRIDVSCSVGDTGAGISPEKFDTIFDPFVQADGSTTRIHG
GTGLGLAIVRRLVEAMDGVISVASEPGMGSTFSFRVRLRGAPDDIASPPPATGWAVAEKSVAVRPLSVLLVDDSAVSRKV
VSLLLESDGHRVTFAGDGVEALAAIGREAFDLVLMDVQMPVMDGFEAMRAIRAGEAAGGARLPIIALTARALAGDRELCL
EAGADDYLAKPVNFSELRRVISRHCCRESKPSALSAENRPDAAGATPPAGTFGELMDELGASVGDRDEDAVERCTRMLKR
AASHLGRTRLVDEIFRLQLASRRGDWERADELLGVVAELLPTTAGACGPPEA

Sequences:

>Translated_772_residues
MVGSLVTYLKKCAASVLGAPYTLLCRLLPRITADLRYGSGYRALFEHAIDGIFIMDAEGHYLDVNPAICSAIGYTRDEFL
ALDWGVLSRGVDSGWAAASLARIVGGEPLREERTVWTRNGDQLTVELSAHLLPDGKILGIARDVSERKRMEESLRSTSEF
LDTILDEAPLPIYITSVDGTLRLANNAWERETGIPRNAAVGRRLNELFPAAMCDQFSEINRRVVESNATAVQDEFLDFGA
GVRVFHTIKFPLRDAAGGVVDVGGISIDITDRSKMEGELRAAHAAAVDSSRAKIDFLANMSHEIRTPMNGVIGTLELLRE
TDLDPRQREYAEIARESAESMLAVINMVLDYSKIESHQLVLEAVPFAIREAVERAVKPFRAVAARKGVMVAADVPPHVPE
TVVGDPVRFSQIVANLVGNAVKFTEQGAITVQLGAAAVDDCRIDVSCSVGDTGAGISPEKFDTIFDPFVQADGSTTRIHG
GTGLGLAIVRRLVEAMDGVISVASEPGMGSTFSFRVRLRGAPDDIASPPPATGWAVAEKSVAVRPLSVLLVDDSAVSRKV
VSLLLESDGHRVTFAGDGVEALAAIGREAFDLVLMDVQMPVMDGFEAMRAIRAGEAAGGARLPIIALTARALAGDRELCL
EAGADDYLAKPVNFSELRRVISRHCCRESKPSALSAENRPDAAGATPPAGTFGELMDELGASVGDRDEDAVERCTRMLKR
AASHLGRTRLVDEIFRLQLASRRGDWERADELLGVVAELLPTTAGACGPPEA
>Mature_772_residues
MVGSLVTYLKKCAASVLGAPYTLLCRLLPRITADLRYGSGYRALFEHAIDGIFIMDAEGHYLDVNPAICSAIGYTRDEFL
ALDWGVLSRGVDSGWAAASLARIVGGEPLREERTVWTRNGDQLTVELSAHLLPDGKILGIARDVSERKRMEESLRSTSEF
LDTILDEAPLPIYITSVDGTLRLANNAWERETGIPRNAAVGRRLNELFPAAMCDQFSEINRRVVESNATAVQDEFLDFGA
GVRVFHTIKFPLRDAAGGVVDVGGISIDITDRSKMEGELRAAHAAAVDSSRAKIDFLANMSHEIRTPMNGVIGTLELLRE
TDLDPRQREYAEIARESAESMLAVINMVLDYSKIESHQLVLEAVPFAIREAVERAVKPFRAVAARKGVMVAADVPPHVPE
TVVGDPVRFSQIVANLVGNAVKFTEQGAITVQLGAAAVDDCRIDVSCSVGDTGAGISPEKFDTIFDPFVQADGSTTRIHG
GTGLGLAIVRRLVEAMDGVISVASEPGMGSTFSFRVRLRGAPDDIASPPPATGWAVAEKSVAVRPLSVLLVDDSAVSRKV
VSLLLESDGHRVTFAGDGVEALAAIGREAFDLVLMDVQMPVMDGFEAMRAIRAGEAAGGARLPIIALTARALAGDRELCL
EAGADDYLAKPVNFSELRRVISRHCCRESKPSALSAENRPDAAGATPPAGTFGELMDELGASVGDRDEDAVERCTRMLKR
AASHLGRTRLVDEIFRLQLASRRGDWERADELLGVVAELLPTTAGACGPPEA

Specific function: Member of the two-component regulatory system BvgS/BvgA. Phosphorylates BvgA via a four-step phosphorelay in response to environmental signals [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788713, Length=537, Percent_Identity=32.4022346368715, Blast_Score=230, Evalue=3e-61,
Organism=Escherichia coli, GI1789149, Length=393, Percent_Identity=33.8422391857506, Blast_Score=221, Evalue=9e-59,
Organism=Escherichia coli, GI48994928, Length=542, Percent_Identity=29.520295202952, Blast_Score=218, Evalue=2e-57,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=39.6887159533074, Blast_Score=186, Evalue=4e-48,
Organism=Escherichia coli, GI87081816, Length=340, Percent_Identity=34.1176470588235, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI1786600, Length=256, Percent_Identity=30.859375, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1788393, Length=232, Percent_Identity=28.448275862069, Blast_Score=94, Evalue=4e-20,
Organism=Escherichia coli, GI1788549, Length=376, Percent_Identity=23.936170212766, Blast_Score=92, Evalue=2e-19,
Organism=Escherichia coli, GI1790436, Length=219, Percent_Identity=28.7671232876712, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1790300, Length=256, Percent_Identity=28.90625, Blast_Score=83, Evalue=8e-17,
Organism=Escherichia coli, GI1786783, Length=217, Percent_Identity=29.4930875576037, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI1790346, Length=219, Percent_Identity=27.8538812785388, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1786912, Length=245, Percent_Identity=28.5714285714286, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI87082128, Length=225, Percent_Identity=28, Blast_Score=75, Evalue=2e-14,
Organism=Escherichia coli, GI87082012, Length=112, Percent_Identity=32.1428571428571, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786911, Length=166, Percent_Identity=32.5301204819277, Blast_Score=70, Evalue=7e-13,
Organism=Escherichia coli, GI1790437, Length=148, Percent_Identity=31.0810810810811, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=250, Percent_Identity=28.8, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=27.3913043478261, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1788550, Length=116, Percent_Identity=34.4827586206897, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1787375, Length=132, Percent_Identity=31.8181818181818, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI1790863, Length=120, Percent_Identity=34.1666666666667, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789808, Length=212, Percent_Identity=29.7169811320755, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1788191, Length=124, Percent_Identity=33.8709677419355, Blast_Score=63, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=191, Percent_Identity=28.7958115183246, Blast_Score=79, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6322044, Length=127, Percent_Identity=31.496062992126, Blast_Score=75, Evalue=4e-14,
Organism=Saccharomyces cerevisiae, GI6323034, Length=186, Percent_Identity=27.9569892473118, Blast_Score=74, Evalue=7e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR001638
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg; PF00497 SBP_bac_3 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82933; Mature: 82933

Theoretical pI: Translated: 4.81; Mature: 4.81

Prosite motif: PS50112 PAS ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVGSLVTYLKKCAASVLGAPYTLLCRLLPRITADLRYGSGYRALFEHAIDGIFIMDAEGH
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCC
YLDVNPAICSAIGYTRDEFLALDWGVLSRGVDSGWAAASLARIVGGEPLREERTVWTRNG
EEECCHHHHHHHCCCCHHHEEEEHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCC
DQLTVELSAHLLPDGKILGIARDVSERKRMEESLRSTSEFLDTILDEAPLPIYITSVDGT
CEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCE
LRLANNAWERETGIPRNAAVGRRLNELFPAAMCDQFSEINRRVVESNATAVQDEFLDFGA
EEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GVRVFHTIKFPLRDAAGGVVDVGGISIDITDRSKMEGELRAAHAAAVDSSRAKIDFLANM
CEEEEEEEECCHHHCCCCEEEECCEEEEECCCHHHCHHHHHHHHHHHCCCCCHHHHHHCC
SHEIRTPMNGVIGTLELLRETDLDPRQREYAEIARESAESMLAVINMVLDYSKIESHQLV
CHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAVPFAIREAVERAVKPFRAVAARKGVMVAADVPPHVPETVVGDPVRFSQIVANLVGNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCH
VKFTEQGAITVQLGAAAVDDCRIDVSCSVGDTGAGISPEKFDTIFDPFVQADGSTTRIHG
HEEECCCCEEEEECCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEC
GTGLGLAIVRRLVEAMDGVISVASEPGMGSTFSFRVRLRGAPDDIASPPPATGWAVAEKS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHCCC
VAVRPLSVLLVDDSAVSRKVVSLLLESDGHRVTFAGDGVEALAAIGREAFDLVLMDVQMP
EEECCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCHHHHHHHEEECCCH
VMDGFEAMRAIRAGEAAGGARLPIIALTARALAGDRELCLEAGADDYLAKPVNFSELRRV
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCHHHCCCCCHHHHHHH
ISRHCCRESKPSALSAENRPDAAGATPPAGTFGELMDELGASVGDRDEDAVERCTRMLKR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AASHLGRTRLVDEIFRLQLASRRGDWERADELLGVVAELLPTTAGACGPPEA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MVGSLVTYLKKCAASVLGAPYTLLCRLLPRITADLRYGSGYRALFEHAIDGIFIMDAEGH
CCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCC
YLDVNPAICSAIGYTRDEFLALDWGVLSRGVDSGWAAASLARIVGGEPLREERTVWTRNG
EEECCHHHHHHHCCCCHHHEEEEHHHHHCCCCCCHHHHHHHHHHCCCCCCCCCCEEECCC
DQLTVELSAHLLPDGKILGIARDVSERKRMEESLRSTSEFLDTILDEAPLPIYITSVDGT
CEEEEEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCE
LRLANNAWERETGIPRNAAVGRRLNELFPAAMCDQFSEINRRVVESNATAVQDEFLDFGA
EEECCCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCC
GVRVFHTIKFPLRDAAGGVVDVGGISIDITDRSKMEGELRAAHAAAVDSSRAKIDFLANM
CEEEEEEEECCHHHCCCCEEEECCEEEEECCCHHHCHHHHHHHHHHHCCCCCHHHHHHCC
SHEIRTPMNGVIGTLELLRETDLDPRQREYAEIARESAESMLAVINMVLDYSKIESHQLV
CHHHCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LEAVPFAIREAVERAVKPFRAVAARKGVMVAADVPPHVPETVVGDPVRFSQIVANLVGNA
HHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCCCCHHHHHHHHHHHCCH
VKFTEQGAITVQLGAAAVDDCRIDVSCSVGDTGAGISPEKFDTIFDPFVQADGSTTRIHG
HEEECCCCEEEEECCEEECCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEEC
GTGLGLAIVRRLVEAMDGVISVASEPGMGSTFSFRVRLRGAPDDIASPPPATGWAVAEKS
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCCCCCCCCCCCHHHHCCC
VAVRPLSVLLVDDSAVSRKVVSLLLESDGHRVTFAGDGVEALAAIGREAFDLVLMDVQMP
EEECCEEEEEECCHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHCHHHHHHHEEECCCH
VMDGFEAMRAIRAGEAAGGARLPIIALTARALAGDRELCLEAGADDYLAKPVNFSELRRV
HHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCHHHHHHCCCCHHHCCCCCHHHHHHH
ISRHCCRESKPSALSAENRPDAAGATPPAGTFGELMDELGASVGDRDEDAVERCTRMLKR
HHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHH
AASHLGRTRLVDEIFRLQLASRRGDWERADELLGVVAELLPTTAGACGPPEA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1791760; 12910271 [H]