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The map label for this gene is carA [H]

Identifier: 39996375

GI number: 39996375

Start: 1387991

End: 1389115

Strand: Direct

Name: carA [H]

Synonym: GSU1273

Alternate gene names: 39996375

Gene position: 1387991-1389115 (Clockwise)

Preceding gene: 39996374

Following gene: 39996376

Centisome position: 36.39

GC content: 62.58

Gene sequence:

>1125_bases
ATGAAAGCAGTCCTAGCGCTCGCCGATGGGCGCGTCTTTGAAGGGAAATCATTCGGTGCCACCGGCGAGGCCGTCGGCGA
GGTGGTCTTCAACACCGCCATGACCGGCTACCAGGAGGTCCTGACCGATCCTTCCTACCGTGGGCAAATGGTCACCATGA
CCTATACCCAGATCGGCAACACCGGCATCAACCCGGAGGACATCGAGAGCAAGCAGCTCTACCTGTCGGGCTTCATCGTC
AAGGAATACCACGATTGCTACTCCAACTGGCGTGCCACCATGAGCCTCGACGCCTATCTCAAGGAGAACGGCGTGGTCGG
CATACAGGGGCTCGATACCCGGGCCCTTACCCGGCACCTGCGGGACAAGGGAGCCCAGAACGGTGTCATCTCCACCGTGG
ATTCGGACCACGAAAGCCTGGTGAAAAAGGCCCGTGCCGTGCCGAGCATGGCCGGCCTCGACCTGGCGACCGGCGTCTCC
TGCGACAAGCCCTACCACTGGACCGAGAAGCTCTGGGACCTGGAGGCCGGGTACACCGCCGCAACACCTGACGAGCTGAA
GTACAAGGTGGTGGCCTACGATTTCGGCATCAAGTACAACATCCTCCGCTGCCTCGTGTCGGCCGGCTGCGACGTGACCG
TGGTGCCCGCAACCTTCCCGGCCGACGAGGCCCTGGCCATGAACCCGGACGGCATTTTCCTCAGCAACGGCCCCGGTGAC
CCGGAGCCCATGACCGCCGTCATCGAGAACATCAGGAAGTTCGTGGGCAAGAAGCCCATCTTCGGCATCTGCCTCGGTCA
CCAGCTCCTGGGCCTGGCCCTGGGGGGGCAGACCATGAAGCTCAAGTTCGGCAACCACGGCTCCAACCTCCCGGTCATGG
ACCTGGACACCCGCAGGGTGGAGATCACTGCCCAGAACCACGGCTTCTCGGTGGATATCGTCTCGCTCGGCCACGCCTGC
GAGCTGGCCCACGAGAACCTGAACGACCAGACCGTTGAAGGGATGAAGCACAAAGACCTCCCGATCTTTTCGGTCCAGCA
CCACCCCGAGGCATCGCCCGGCCCCCACGATTCCCACTACCTGTTCGGGCGCTTCGTGGAGTTGATGGAGAAGGAAAAGG
CATAG

Upstream 100 bases:

>100_bases
CAGAGGATGAAATCCGGGCGCGCCGCTTGCCGCGCCCGTTGAAGAGCGGAACCGGGCGCGGCAAGCAGCGCCCTTACGCA
CAATACACAGGAGCATGTTC

Downstream 100 bases:

>100_bases
GGGTGGAGCTGGTTTCGCCCACGAGCGAGGGCGATCATAAGGATCGCCCCTACGGAACCATGCGGTATATCGATCTTTAT
CAATCAGGCGAATTATTGCA

Product: carbamoyl phosphate synthase small subunit

Products: NA

Alternate protein names: Carbamoyl-phosphate synthetase glutamine chain [H]

Number of amino acids: Translated: 374; Mature: 374

Protein sequence:

>374_residues
MKAVLALADGRVFEGKSFGATGEAVGEVVFNTAMTGYQEVLTDPSYRGQMVTMTYTQIGNTGINPEDIESKQLYLSGFIV
KEYHDCYSNWRATMSLDAYLKENGVVGIQGLDTRALTRHLRDKGAQNGVISTVDSDHESLVKKARAVPSMAGLDLATGVS
CDKPYHWTEKLWDLEAGYTAATPDELKYKVVAYDFGIKYNILRCLVSAGCDVTVVPATFPADEALAMNPDGIFLSNGPGD
PEPMTAVIENIRKFVGKKPIFGICLGHQLLGLALGGQTMKLKFGNHGSNLPVMDLDTRRVEITAQNHGFSVDIVSLGHAC
ELAHENLNDQTVEGMKHKDLPIFSVQHHPEASPGPHDSHYLFGRFVELMEKEKA

Sequences:

>Translated_374_residues
MKAVLALADGRVFEGKSFGATGEAVGEVVFNTAMTGYQEVLTDPSYRGQMVTMTYTQIGNTGINPEDIESKQLYLSGFIV
KEYHDCYSNWRATMSLDAYLKENGVVGIQGLDTRALTRHLRDKGAQNGVISTVDSDHESLVKKARAVPSMAGLDLATGVS
CDKPYHWTEKLWDLEAGYTAATPDELKYKVVAYDFGIKYNILRCLVSAGCDVTVVPATFPADEALAMNPDGIFLSNGPGD
PEPMTAVIENIRKFVGKKPIFGICLGHQLLGLALGGQTMKLKFGNHGSNLPVMDLDTRRVEITAQNHGFSVDIVSLGHAC
ELAHENLNDQTVEGMKHKDLPIFSVQHHPEASPGPHDSHYLFGRFVELMEKEKA
>Mature_374_residues
MKAVLALADGRVFEGKSFGATGEAVGEVVFNTAMTGYQEVLTDPSYRGQMVTMTYTQIGNTGINPEDIESKQLYLSGFIV
KEYHDCYSNWRATMSLDAYLKENGVVGIQGLDTRALTRHLRDKGAQNGVISTVDSDHESLVKKARAVPSMAGLDLATGVS
CDKPYHWTEKLWDLEAGYTAATPDELKYKVVAYDFGIKYNILRCLVSAGCDVTVVPATFPADEALAMNPDGIFLSNGPGD
PEPMTAVIENIRKFVGKKPIFGICLGHQLLGLALGGQTMKLKFGNHGSNLPVMDLDTRRVEITAQNHGFSVDIVSLGHAC
ELAHENLNDQTVEGMKHKDLPIFSVQHHPEASPGPHDSHYLFGRFVELMEKEKA

Specific function: Arginine biosynthesis. Pyrimidine biosynthesis; first step. [C]

COG id: COG0505

COG function: function code EF; Carbamoylphosphate synthase small subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Homo sapiens, GI18105007, Length=390, Percent_Identity=38.974358974359, Blast_Score=261, Evalue=1e-69,
Organism=Homo sapiens, GI169790915, Length=393, Percent_Identity=37.1501272264631, Blast_Score=234, Evalue=9e-62,
Organism=Homo sapiens, GI21361331, Length=393, Percent_Identity=37.1501272264631, Blast_Score=234, Evalue=1e-61,
Organism=Escherichia coli, GI1786215, Length=374, Percent_Identity=53.2085561497326, Blast_Score=392, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI193204318, Length=390, Percent_Identity=37.6923076923077, Blast_Score=244, Evalue=8e-65,
Organism=Saccharomyces cerevisiae, GI6324878, Length=386, Percent_Identity=41.4507772020725, Blast_Score=280, Evalue=3e-76,
Organism=Saccharomyces cerevisiae, GI6322331, Length=396, Percent_Identity=36.8686868686869, Blast_Score=273, Evalue=3e-74,
Organism=Drosophila melanogaster, GI45555749, Length=389, Percent_Identity=38.3033419023136, Blast_Score=242, Evalue=4e-64,
Organism=Drosophila melanogaster, GI24642586, Length=389, Percent_Identity=38.3033419023136, Blast_Score=241, Evalue=5e-64,

Paralogues:

None

Copy number: 620 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2599 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR006274
- InterPro:   IPR002474
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991 [H]

Pfam domain/function: PF00988 CPSase_sm_chain; PF00117 GATase [H]

EC number: =6.3.5.5 [H]

Molecular weight: Translated: 40868; Mature: 40868

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAVLALADGRVFEGKSFGATGEAVGEVVFNTAMTGYQEVLTDPSYRGQMVTMTYTQIGN
CCEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCC
TGINPEDIESKQLYLSGFIVKEYHDCYSNWRATMSLDAYLKENGVVGIQGLDTRALTRHL
CCCCCCCCCCCEEEEEEEHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCHHHHHHHH
RDKGAQNGVISTVDSDHESLVKKARAVPSMAGLDLATGVSCDKPYHWTEKLWDLEAGYTA
HHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCC
ATPDELKYKVVAYDFGIKYNILRCLVSAGCDVTVVPATFPADEALAMNPDGIFLSNGPGD
CCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCEEECCCCCC
PEPMTAVIENIRKFVGKKPIFGICLGHQLLGLALGGQTMKLKFGNHGSNLPVMDLDTRRV
CHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHEECCCEEEEEECCCCCCCCEEECCCCEE
EITAQNHGFSVDIVSLGHACELAHENLNDQTVEGMKHKDLPIFSVQHHPEASPGPHDSHY
EEEECCCCEEEEEEECCCHHHHHHCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCCHH
LFGRFVELMEKEKA
HHHHHHHHHHHCCC
>Mature Secondary Structure
MKAVLALADGRVFEGKSFGATGEAVGEVVFNTAMTGYQEVLTDPSYRGQMVTMTYTQIGN
CCEEEEECCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCC
TGINPEDIESKQLYLSGFIVKEYHDCYSNWRATMSLDAYLKENGVVGIQGLDTRALTRHL
CCCCCCCCCCCEEEEEEEHHHHHHHHHHCCEEEEEEEEEECCCCEEEEECCCHHHHHHHH
RDKGAQNGVISTVDSDHESLVKKARAVPSMAGLDLATGVSCDKPYHWTEKLWDLEAGYTA
HHCCCCCCEEEECCCCHHHHHHHHHCCCCCCCCHHHCCCCCCCCCCHHHHHHHCCCCCCC
ATPDELKYKVVAYDFGIKYNILRCLVSAGCDVTVVPATFPADEALAMNPDGIFLSNGPGD
CCCCCCEEEEEEEECCCHHHHHHHHHHCCCCEEEEECCCCCCCCEEECCCCEEECCCCCC
PEPMTAVIENIRKFVGKKPIFGICLGHQLLGLALGGQTMKLKFGNHGSNLPVMDLDTRRV
CHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHEECCCEEEEEECCCCCCCCEEECCCCEE
EITAQNHGFSVDIVSLGHACELAHENLNDQTVEGMKHKDLPIFSVQHHPEASPGPHDSHY
EEEECCCCEEEEEEECCCHHHHHHCCCCCHHHCCCCCCCCCEEEEECCCCCCCCCCCCHH
LFGRFVELMEKEKA
HHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA