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The map label for this gene is ftsY [H]

Identifier: 39996234

GI number: 39996234

Start: 1217706

End: 1218758

Strand: Direct

Name: ftsY [H]

Synonym: GSU1132

Alternate gene names: 39996234

Gene position: 1217706-1218758 (Clockwise)

Preceding gene: 39996233

Following gene: 39996235

Centisome position: 31.93

GC content: 60.97

Gene sequence:

>1053_bases
ATGGCGGAAGAACGGAAGGGCTTTTTCAAGGGACTTTGGGGTAAGGTTACCGGCGGCGATCGTGACCAGGAAGAGGCAGT
CAATGAAACGACGTCCGCCGTTGCGGATGTCGCTGCACCGCCGGAGCAGGAAGACCGGCGCCCCGGATTGTTCGAGCGGC
TCAAACAGGGGCTGAGCAAGACCCGCGATAGCCTGGTGGGACGCATCGATCGTCTCGTGCTCGGCAAGAAGGAGATTGAC
GCCGACACCCTTGAGGAGCTGGAGGAGATACTCATTACCGCCGATCTGGGCGTCCAGACCACCGTCGAGTTGATCAGGGG
ATTGGAGCAGCGCCTCTCCCGCAACGAGCTCAAGGACGGCGAGGCCCTCCGGGAGGCGCTCAAGGAGGATATCCACGGTC
GCCTTGCCCGTGACGCCCATCAACTGGACGTAACAGGTGCCTCTCCCTTCGTCATCATGGTCATCGGCGTCAACGGTGTC
GGCAAGACTACTACCATTGGCAAGCTCGCGGCCCGGTTTACCGCCCAGGGGAAAAAAGTGATTCTGGCCGCCGGCGACAC
CTTCCGCGCTGCTGCCGCCGAGCAACTCCAGATATGGGGCGAGCGTACCGGCGTCGACGTGATCCGCCACAAGGAAGGGG
CGGATCCGTCTGCCGTTGTGTTCGACAGCATCAAGGCGGCCGTGGCTCGTGGCGCGGACATCCTCATCGTCGACACCGCC
GGCCGTCTCCATACCAAGGTAAACCTCATGGAGGAACTCAAAAAAGTCCGCCGCATCATGTCGCGGGAGATCCCCGGGGC
TCCCCACGAGACGTTGCTGGTTCTTGACGCGGCAACGGGACAGAATGCCCTCTCGCAGGCGAAACTCTTCAAGGAGGCAG
CCCAGGTTACCGGCATCGCCCTGACAAAGCTTGACGGTACGGCAAAGGGAGGAATTGTGGTTGCAATCTGCAATGAGTTC
AGGATTCCCGTCCGTTACATCGGCGTCGGCGAGGGCATCGACGACCTGCGGGATTTCGATCCCTCCCAATTTGTGGAAGC
CCTCTTTCAATAA

Upstream 100 bases:

>100_bases
TATTCCCTTGTGATGACGCTGGAGCGCGGTGCCATACCCGGCCGGGCGCTCATTCACTTCAGATCGGCCGTAGAATGTCT
GGCCAAGGAGATATACTGAG

Downstream 100 bases:

>100_bases
ATGACCTTGACTAAACAACAGAGCAGAATATATTATTTTATCCCTAAAAAGGTGTTTGCTTATGGATACGGAACTGTTTT
CGGATCTGGAACGGCGTCTT

Product: cell division protein FtsY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MAEERKGFFKGLWGKVTGGDRDQEEAVNETTSAVADVAAPPEQEDRRPGLFERLKQGLSKTRDSLVGRIDRLVLGKKEID
ADTLEELEEILITADLGVQTTVELIRGLEQRLSRNELKDGEALREALKEDIHGRLARDAHQLDVTGASPFVIMVIGVNGV
GKTTTIGKLAARFTAQGKKVILAAGDTFRAAAAEQLQIWGERTGVDVIRHKEGADPSAVVFDSIKAAVARGADILIVDTA
GRLHTKVNLMEELKKVRRIMSREIPGAPHETLLVLDAATGQNALSQAKLFKEAAQVTGIALTKLDGTAKGGIVVAICNEF
RIPVRYIGVGEGIDDLRDFDPSQFVEALFQ

Sequences:

>Translated_350_residues
MAEERKGFFKGLWGKVTGGDRDQEEAVNETTSAVADVAAPPEQEDRRPGLFERLKQGLSKTRDSLVGRIDRLVLGKKEID
ADTLEELEEILITADLGVQTTVELIRGLEQRLSRNELKDGEALREALKEDIHGRLARDAHQLDVTGASPFVIMVIGVNGV
GKTTTIGKLAARFTAQGKKVILAAGDTFRAAAAEQLQIWGERTGVDVIRHKEGADPSAVVFDSIKAAVARGADILIVDTA
GRLHTKVNLMEELKKVRRIMSREIPGAPHETLLVLDAATGQNALSQAKLFKEAAQVTGIALTKLDGTAKGGIVVAICNEF
RIPVRYIGVGEGIDDLRDFDPSQFVEALFQ
>Mature_349_residues
AEERKGFFKGLWGKVTGGDRDQEEAVNETTSAVADVAAPPEQEDRRPGLFERLKQGLSKTRDSLVGRIDRLVLGKKEIDA
DTLEELEEILITADLGVQTTVELIRGLEQRLSRNELKDGEALREALKEDIHGRLARDAHQLDVTGASPFVIMVIGVNGVG
KTTTIGKLAARFTAQGKKVILAAGDTFRAAAAEQLQIWGERTGVDVIRHKEGADPSAVVFDSIKAAVARGADILIVDTAG
RLHTKVNLMEELKKVRRIMSREIPGAPHETLLVLDAATGQNALSQAKLFKEAAQVTGIALTKLDGTAKGGIVVAICNEFR
IPVRYIGVGEGIDDLRDFDPSQFVEALFQ

Specific function: Functional homolog of SRP receptor. Probably involved in the reception and insertion of a subset of proteins at the cytoplasmic membrane. Binds to the ribosome in the presence of the SRP particle and a non-hydrolyzable GTP analog. This abolishes trigger f

COG id: COG0552

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=270, Percent_Identity=29.6296296296296, Blast_Score=122, Evalue=7e-28,
Organism=Homo sapiens, GI226371618, Length=199, Percent_Identity=34.6733668341709, Blast_Score=118, Evalue=8e-27,
Organism=Homo sapiens, GI295424842, Length=333, Percent_Identity=28.2282282282282, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI23308697, Length=226, Percent_Identity=31.858407079646, Blast_Score=99, Evalue=9e-21,
Organism=Homo sapiens, GI89061728, Length=135, Percent_Identity=33.3333333333333, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1789874, Length=310, Percent_Identity=56.7741935483871, Blast_Score=324, Evalue=6e-90,
Organism=Escherichia coli, GI1788963, Length=300, Percent_Identity=33.3333333333333, Blast_Score=158, Evalue=6e-40,
Organism=Caenorhabditis elegans, GI17539958, Length=285, Percent_Identity=29.8245614035088, Blast_Score=130, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI193206261, Length=312, Percent_Identity=28.8461538461538, Blast_Score=105, Evalue=4e-23,
Organism=Saccharomyces cerevisiae, GI6325345, Length=199, Percent_Identity=37.1859296482412, Blast_Score=135, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6320498, Length=321, Percent_Identity=28.0373831775701, Blast_Score=92, Evalue=1e-19,
Organism=Drosophila melanogaster, GI17647949, Length=274, Percent_Identity=29.9270072992701, Blast_Score=122, Evalue=4e-28,
Organism=Drosophila melanogaster, GI24641198, Length=302, Percent_Identity=24.8344370860927, Blast_Score=89, Evalue=5e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004390
- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N [H]

EC number: NA

Molecular weight: Translated: 37934; Mature: 37803

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEERKGFFKGLWGKVTGGDRDQEEAVNETTSAVADVAAPPEQEDRRPGLFERLKQGLSK
CCCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TRDSLVGRIDRLVLGKKEIDADTLEELEEILITADLGVQTTVELIRGLEQRLSRNELKDG
HHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
EALREALKEDIHGRLARDAHQLDVTGASPFVIMVIGVNGVGKTTTIGKLAARFTAQGKKV
HHHHHHHHHHHHHHHHHCHHHEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEE
ILAAGDTFRAAAAEQLQIWGERTGVDVIRHKEGADPSAVVFDSIKAAVARGADILIVDTA
EEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECC
GRLHTKVNLMEELKKVRRIMSREIPGAPHETLLVLDAATGQNALSQAKLFKEAAQVTGIA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEE
LTKLDGTAKGGIVVAICNEFRIPVRYIGVGEGIDDLRDFDPSQFVEALFQ
EEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHC
>Mature Secondary Structure 
AEERKGFFKGLWGKVTGGDRDQEEAVNETTSAVADVAAPPEQEDRRPGLFERLKQGLSK
CCCHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHH
TRDSLVGRIDRLVLGKKEIDADTLEELEEILITADLGVQTTVELIRGLEQRLSRNELKDG
HHHHHHHHHHHHHHCCHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
EALREALKEDIHGRLARDAHQLDVTGASPFVIMVIGVNGVGKTTTIGKLAARFTAQGKKV
HHHHHHHHHHHHHHHHHCHHHEEECCCCCEEEEEEECCCCCCCHHHHHHHHHHHCCCCEE
ILAAGDTFRAAAAEQLQIWGERTGVDVIRHKEGADPSAVVFDSIKAAVARGADILIVDTA
EEECCCCHHHHHHHHHHHHHCCCCHHHHHCCCCCCCHHHHHHHHHHHHHCCCCEEEEECC
GRLHTKVNLMEELKKVRRIMSREIPGAPHETLLVLDAATGQNALSQAKLFKEAAQVTGIA
CHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCEE
LTKLDGTAKGGIVVAICNEFRIPVRYIGVGEGIDDLRDFDPSQFVEALFQ
EEECCCCCCCCEEEEEECCCCCCEEEEECCCCHHHHHCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 3025556; 8041620; 9278503; 2161989; 8194520; 9002525 [H]