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The map label for this gene is smc [H]

Identifier: 39996232

GI number: 39996232

Start: 1213798

End: 1217325

Strand: Direct

Name: smc [H]

Synonym: GSU1130

Alternate gene names: 39996232

Gene position: 1213798-1217325 (Clockwise)

Preceding gene: 39996230

Following gene: 39996233

Centisome position: 31.82

GC content: 62.73

Gene sequence:

>3528_bases
ATGAAGATCAAGCGCTTGGACATCGTTGGTTTTAAATCGTTCGTCGACAAGGTCTCCTTCGACTTTCAGCAGGGGATTAC
CGGCATTGTCGGGCCCAACGGCTGCGGCAAGTCGAACGTGGTCGACGCCATCCGCTGGGCCATGGGTGAACAGTCGGCCA
AGAACCTGCGCGGCCGGTCCATGGAGGACATCATTTTCGGCGGCAGCGAGTTCCGCAAGCCCCTCGGCATGGCCGAAGTC
TCCATGGTTTTTGCCACCGATGACGGCCGGGTGCCGGCCAAGTATCTGAGCTACAGCGAAATACAGATTACCAGACGCCT
CTACCGGGATGGGGAGAGCGAGTACTTTCTCAACAAAACCCCCTGCCGGCTCATGGACATCACCGAACTCTTCATGGACA
CCGGCGTCGGTGCCCGCGCCTACTCGATCATCGAGCAGGGCAAGATCGGGATGATCCTCCACTCCAAGCCCGAAGAGCGC
CGCTTCATCATCGAAGAGGCGGCCGGGGTCACCAAGTTCAAGGCCCGCAAACAGGTCGCGCTCAAGAAGATAGATCTCAC
CCGCCAGAACCTGCTCAGAATCGGCGACATCCTTTCCGAGATCAAGCGCCAGCTCAACTCTCTCCAGCGGCAGGTGAAGA
AGGCTGAACGGTTCAGGGAATATCGCGAGGAGCTCCGCGAGATCGAAATTCATGCCTCGGTCCGGCGGTTCACTGCCCTT
GACGCGGAAAAGGAGCGGATCGAGGGCCTGCTGCGCGAGGCGGTTTCCCGCGAGAGCACTCTCACTGCCGACCTTGAGCG
ACGGGACCTGGAGCTTGCCGAGCATCGGCTTGCCCTGGCCGAGCGGGAAAAGGAAGTCGTCACCGCGCAGGAAGGGCTTT
TCCGGCAGAAGGCGGATATCCAGGCATGCGAAAGCCGGATCGAGTTCCAGCGCCGTGAGCTGTCCTCCCTGGAGCGCCAG
CAGGAGCGCGTGGCCGTCGAGCTCGCGACCGCCGGGTCGCAGCTTGTGGCCGCCGAGGAAGAGTTCGCCCGACTGGTGGA
GCAGAGCGGATCCTTTGCCGTTGAGGTGGCAGGGGAAGAGGAAAGCCTCCAAACGCGCGAGATGGAACTGGAAGAGATGA
CCGGCGCCGAGCGGGAACTCGCCGCCCATTTGGACGAAGCCCGCCGTGAGCTTTTCTCGCTCTTGTCCGAGATCGCCCAG
CTCAATAACCAGCGAACCGCCGCTGTCCGCCGTCTGGAGGGTCTCGCGGAGCGTGCTGACCGCAACCGTCGGGAGGGAAC
CCTGCTTCAGGAGCGGCTGGTGGAGGCCACGGGCAAGGTGCATGAGCTCGACGGCACGGTGTCCGGTCTTGGCCGGACAA
AGGCCGAACTTCAGGAGCGTCTTCCGGTCGTGATCCGCCGCGAAGAGGAGATTCGGCAGCGGCTGGCCGAGGCCGAACGG
GAATTCGTCACCCGCCGGGACGAGCTCTCGCGGGCGGCCTCGCGTCTCCACTCGCTTCAGGAACTGGAGTCCCAGTTTGC
CGGATACGGCCAGGGGGTTCGCAACCTTTTCCTGTCCGAGCGTTTTGCCGGACGGTTCGGCGGCGTGCTTGCCGATGCGG
TGGAGACCGGCGCCGATTACGAGACGGCCCTGGAGGCAGTGTGCGCCGAGCGGCTCCAGTATGTGCTCAGCGAGAGCGAC
GAGGCGGCCCTGGACGCCATTGCCCATCTCAAGGAATCGGGCGGCGGCCGCTGCGGCATTATCGTGGCGGGCATCCCGGC
CGATGACCGTTCATCCGTTACCGGGGCCACGCCCCTTCTGGATCGGGTTTCCATTGCCGCAGCCTGGCGCCCCCTGATCG
AACCGCTGTTGGCCGATGTCCATCTGGCGGATACCCTGGCCCAGGCCCTTTCCCTGTCCCGGCAGTATCCTCGGGCAACC
TTCGTTACCCTCCAGGGTGACCTCGCCTTTGGCGGGGGGATCGTGAATGGCGGTTCCGCCGAGAACGCCGGCCAGGGACT
TGTTCACAAGAAGAGAGAGATCAGGGAGCTTTCCGGAACCGTGGAGCGCCTCGAATCTGCTGTGCGTGAAACCGAGACGC
GCCGGGAGGAGCTCCGGGGGGAGCGTTCCCGGCTGGAGGAGGAGGTGCGCGACCTTCGGCAAATCCTCCACCAGACGGAG
ATCCAGTTCGTCAATGCCGAGAAGGATCTTCAGCGGGCCCGCGAAGAGTGCCAGCGGATCGAGGAGCGAATCGCCATTGC
GGGGATTGAGGACGAGCAGCTTCAGGACGAACGCAGGACTCTGGACGAAGAGATTGCCGACGCCGACGGCCGCCGCGCTG
AGCGCGAGGCGAAGCGGGAAGCGCTCGATGCCGAAGTGGCGAGAACGCAGGAAGCCCTGACGGTTAGCCGCCGTACAATC
GAAGCCGCCCGTGATGCGGTCACGGCTCTCAAGGTCAAGGGAGCCCAGCTCAGGGAAAAGCGGGAGGCCGCGTCCCGGGC
CACGGTACGAACCGAGGAGTCGATCCGGGACCTGCGTGAACGCATTGGCCGGCTACGGGGGGAAGGGGAATCGTCAGCCG
CCGAACGGGAGCACCTTGCGGTTGCGATTACCGCCGCCGAGGACGATCTCAAGGGCCATCTTGCGGCGTATGCCGAAGCC
GAGACATTATCCCGGAGCCTTCGCTCGGAATTTGATGCCCGGGTCGAGGCGGTTCGGGTAGAAGAGACGGGGCTGCGGGA
GCTTCGTCATCAGTGCGAGGCAGCCCGGGACGAAGTGGCTGCCCATAAGCTCACTCTGTCCGGGCTCACCCTTGAACTCA
ATCATCTGATTTCTTCCCTGGCGGATAAGTACCGGCTGGAGATGCGCGAGGTCATGCCATCCTATGCCGACAGGCCCTTT
GACGAGGAAGCGGCCGCTCGTCGCCAGGCCGAGCTCGGCCGGTTGATCGACGAAATCGGTGAAGTGAACCTGACGGCCAT
TGAGGAGTACCGGGAGCTGGAGGAGCGGTTCGCGTTCCTCTCGTCGCAGAAAGATGATCTGGAGGAGTCTCTTCAATCGC
TCCAGCAGGCTATCCAGCGAATCAACCGGACCACCCGCAAGCGTTTTCTGGAAACCTTCACTCTGGTCAACGAGAAGTTC
CAGGAGGTCTTCCCCCGACTGTTTTGCGGAGGCCGGGCTGAACTGCGGCTCACCAACGAGGAAGACCTGCTGGAGACCGG
GATCGATATCATTGTTCAGCCCCCCGGGAAAAAACTCCAGAACGTGACCCTCCTCTCGGGCGGTGAGAAGGCACTTACCG
CAGTGGCGCTGATCTTTTCCATCTTCCTCATCAAGCCGACACCCTTCTGTCTTCTCGATGAGGTCGACGCCCCGCTTGAC
GACGCCAATATCGGCCGGTTCAACGATATGGTGCGGGAGATGAGCGATGTGTCGCAGTTCATCATCATTACCCACAACAA
GGCCACCATGGCCGTTGCCGACACTCTTTACGGCGTGACCATGGAGGAGCCCGGGGTGTCTAAGAGCGTGTCGGTCAAGC
TGAACTAA

Upstream 100 bases:

>100_bases
GCAAGCATCCCGTAGCCGCGGCAGTGCGTGAAGGGGCTCTGGTAAACGTTCCGCTTTGCCTTTGCAAAGCCATCTACCCT
CTGCTACTATAGCCCGGTTT

Downstream 100 bases:

>100_bases
CCAACGTCCGAGGTGATTCGTGCCGTTCAAAAGGATTCTGACCGAGCTGGTCGATGCGGTTCCCGGCGCAACCGGCGCAA
TTCTTGCCGACTGGGAGGGG

Product: chromosome segregation SMC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 1175; Mature: 1175

Protein sequence:

>1175_residues
MKIKRLDIVGFKSFVDKVSFDFQQGITGIVGPNGCGKSNVVDAIRWAMGEQSAKNLRGRSMEDIIFGGSEFRKPLGMAEV
SMVFATDDGRVPAKYLSYSEIQITRRLYRDGESEYFLNKTPCRLMDITELFMDTGVGARAYSIIEQGKIGMILHSKPEER
RFIIEEAAGVTKFKARKQVALKKIDLTRQNLLRIGDILSEIKRQLNSLQRQVKKAERFREYREELREIEIHASVRRFTAL
DAEKERIEGLLREAVSRESTLTADLERRDLELAEHRLALAEREKEVVTAQEGLFRQKADIQACESRIEFQRRELSSLERQ
QERVAVELATAGSQLVAAEEEFARLVEQSGSFAVEVAGEEESLQTREMELEEMTGAERELAAHLDEARRELFSLLSEIAQ
LNNQRTAAVRRLEGLAERADRNRREGTLLQERLVEATGKVHELDGTVSGLGRTKAELQERLPVVIRREEEIRQRLAEAER
EFVTRRDELSRAASRLHSLQELESQFAGYGQGVRNLFLSERFAGRFGGVLADAVETGADYETALEAVCAERLQYVLSESD
EAALDAIAHLKESGGGRCGIIVAGIPADDRSSVTGATPLLDRVSIAAAWRPLIEPLLADVHLADTLAQALSLSRQYPRAT
FVTLQGDLAFGGGIVNGGSAENAGQGLVHKKREIRELSGTVERLESAVRETETRREELRGERSRLEEEVRDLRQILHQTE
IQFVNAEKDLQRAREECQRIEERIAIAGIEDEQLQDERRTLDEEIADADGRRAEREAKREALDAEVARTQEALTVSRRTI
EAARDAVTALKVKGAQLREKREAASRATVRTEESIRDLRERIGRLRGEGESSAAEREHLAVAITAAEDDLKGHLAAYAEA
ETLSRSLRSEFDARVEAVRVEETGLRELRHQCEAARDEVAAHKLTLSGLTLELNHLISSLADKYRLEMREVMPSYADRPF
DEEAAARRQAELGRLIDEIGEVNLTAIEEYRELEERFAFLSSQKDDLEESLQSLQQAIQRINRTTRKRFLETFTLVNEKF
QEVFPRLFCGGRAELRLTNEEDLLETGIDIIVQPPGKKLQNVTLLSGGEKALTAVALIFSIFLIKPTPFCLLDEVDAPLD
DANIGRFNDMVREMSDVSQFIIITHNKATMAVADTLYGVTMEEPGVSKSVSVKLN

Sequences:

>Translated_1175_residues
MKIKRLDIVGFKSFVDKVSFDFQQGITGIVGPNGCGKSNVVDAIRWAMGEQSAKNLRGRSMEDIIFGGSEFRKPLGMAEV
SMVFATDDGRVPAKYLSYSEIQITRRLYRDGESEYFLNKTPCRLMDITELFMDTGVGARAYSIIEQGKIGMILHSKPEER
RFIIEEAAGVTKFKARKQVALKKIDLTRQNLLRIGDILSEIKRQLNSLQRQVKKAERFREYREELREIEIHASVRRFTAL
DAEKERIEGLLREAVSRESTLTADLERRDLELAEHRLALAEREKEVVTAQEGLFRQKADIQACESRIEFQRRELSSLERQ
QERVAVELATAGSQLVAAEEEFARLVEQSGSFAVEVAGEEESLQTREMELEEMTGAERELAAHLDEARRELFSLLSEIAQ
LNNQRTAAVRRLEGLAERADRNRREGTLLQERLVEATGKVHELDGTVSGLGRTKAELQERLPVVIRREEEIRQRLAEAER
EFVTRRDELSRAASRLHSLQELESQFAGYGQGVRNLFLSERFAGRFGGVLADAVETGADYETALEAVCAERLQYVLSESD
EAALDAIAHLKESGGGRCGIIVAGIPADDRSSVTGATPLLDRVSIAAAWRPLIEPLLADVHLADTLAQALSLSRQYPRAT
FVTLQGDLAFGGGIVNGGSAENAGQGLVHKKREIRELSGTVERLESAVRETETRREELRGERSRLEEEVRDLRQILHQTE
IQFVNAEKDLQRAREECQRIEERIAIAGIEDEQLQDERRTLDEEIADADGRRAEREAKREALDAEVARTQEALTVSRRTI
EAARDAVTALKVKGAQLREKREAASRATVRTEESIRDLRERIGRLRGEGESSAAEREHLAVAITAAEDDLKGHLAAYAEA
ETLSRSLRSEFDARVEAVRVEETGLRELRHQCEAARDEVAAHKLTLSGLTLELNHLISSLADKYRLEMREVMPSYADRPF
DEEAAARRQAELGRLIDEIGEVNLTAIEEYRELEERFAFLSSQKDDLEESLQSLQQAIQRINRTTRKRFLETFTLVNEKF
QEVFPRLFCGGRAELRLTNEEDLLETGIDIIVQPPGKKLQNVTLLSGGEKALTAVALIFSIFLIKPTPFCLLDEVDAPLD
DANIGRFNDMVREMSDVSQFIIITHNKATMAVADTLYGVTMEEPGVSKSVSVKLN
>Mature_1175_residues
MKIKRLDIVGFKSFVDKVSFDFQQGITGIVGPNGCGKSNVVDAIRWAMGEQSAKNLRGRSMEDIIFGGSEFRKPLGMAEV
SMVFATDDGRVPAKYLSYSEIQITRRLYRDGESEYFLNKTPCRLMDITELFMDTGVGARAYSIIEQGKIGMILHSKPEER
RFIIEEAAGVTKFKARKQVALKKIDLTRQNLLRIGDILSEIKRQLNSLQRQVKKAERFREYREELREIEIHASVRRFTAL
DAEKERIEGLLREAVSRESTLTADLERRDLELAEHRLALAEREKEVVTAQEGLFRQKADIQACESRIEFQRRELSSLERQ
QERVAVELATAGSQLVAAEEEFARLVEQSGSFAVEVAGEEESLQTREMELEEMTGAERELAAHLDEARRELFSLLSEIAQ
LNNQRTAAVRRLEGLAERADRNRREGTLLQERLVEATGKVHELDGTVSGLGRTKAELQERLPVVIRREEEIRQRLAEAER
EFVTRRDELSRAASRLHSLQELESQFAGYGQGVRNLFLSERFAGRFGGVLADAVETGADYETALEAVCAERLQYVLSESD
EAALDAIAHLKESGGGRCGIIVAGIPADDRSSVTGATPLLDRVSIAAAWRPLIEPLLADVHLADTLAQALSLSRQYPRAT
FVTLQGDLAFGGGIVNGGSAENAGQGLVHKKREIRELSGTVERLESAVRETETRREELRGERSRLEEEVRDLRQILHQTE
IQFVNAEKDLQRAREECQRIEERIAIAGIEDEQLQDERRTLDEEIADADGRRAEREAKREALDAEVARTQEALTVSRRTI
EAARDAVTALKVKGAQLREKREAASRATVRTEESIRDLRERIGRLRGEGESSAAEREHLAVAITAAEDDLKGHLAAYAEA
ETLSRSLRSEFDARVEAVRVEETGLRELRHQCEAARDEVAAHKLTLSGLTLELNHLISSLADKYRLEMREVMPSYADRPF
DEEAAARRQAELGRLIDEIGEVNLTAIEEYRELEERFAFLSSQKDDLEESLQSLQQAIQRINRTTRKRFLETFTLVNEKF
QEVFPRLFCGGRAELRLTNEEDLLETGIDIIVQPPGKKLQNVTLLSGGEKALTAVALIFSIFLIKPTPFCLLDEVDAPLD
DANIGRFNDMVREMSDVSQFIIITHNKATMAVADTLYGVTMEEPGVSKSVSVKLN

Specific function: Plays an important role in chromosome structure and partitioning. Essential for chromosome partition [H]

COG id: COG1196

COG function: function code D; Chromosome segregation ATPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SMC family [H]

Homologues:

Organism=Homo sapiens, GI110347425, Length=1240, Percent_Identity=23.0645161290323, Blast_Score=170, Evalue=7e-42,
Organism=Homo sapiens, GI110347420, Length=1240, Percent_Identity=23.0645161290323, Blast_Score=170, Evalue=7e-42,
Organism=Homo sapiens, GI110347418, Length=1240, Percent_Identity=23.0645161290323, Blast_Score=170, Evalue=7e-42,
Organism=Homo sapiens, GI4885399, Length=1270, Percent_Identity=23.3858267716535, Blast_Score=170, Evalue=1e-41,
Organism=Homo sapiens, GI50658065, Length=706, Percent_Identity=24.6458923512748, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI50658063, Length=706, Percent_Identity=24.6458923512748, Blast_Score=137, Evalue=5e-32,
Organism=Homo sapiens, GI30581135, Length=192, Percent_Identity=30.7291666666667, Blast_Score=94, Evalue=8e-19,
Organism=Homo sapiens, GI71565160, Length=782, Percent_Identity=21.8670076726343, Blast_Score=79, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI212656546, Length=1291, Percent_Identity=22.5406661502711, Blast_Score=165, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17553272, Length=158, Percent_Identity=33.5443037974684, Blast_Score=105, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI193210872, Length=190, Percent_Identity=33.6842105263158, Blast_Score=91, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI193202684, Length=192, Percent_Identity=28.6458333333333, Blast_Score=86, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17535279, Length=237, Percent_Identity=29.957805907173, Blast_Score=81, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI17552844, Length=136, Percent_Identity=30.1470588235294, Blast_Score=71, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI115532288, Length=101, Percent_Identity=38.6138613861386, Blast_Score=68, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322387, Length=1288, Percent_Identity=21.195652173913, Blast_Score=179, Evalue=3e-45,
Organism=Saccharomyces cerevisiae, GI6323115, Length=1337, Percent_Identity=21.9147344801795, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6321144, Length=1242, Percent_Identity=21.7391304347826, Blast_Score=137, Evalue=9e-33,
Organism=Saccharomyces cerevisiae, GI6321104, Length=234, Percent_Identity=28.6324786324786, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24642555, Length=1253, Percent_Identity=22.5059856344773, Blast_Score=142, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24649535, Length=1265, Percent_Identity=21.5810276679842, Blast_Score=140, Evalue=5e-33,
Organism=Drosophila melanogaster, GI19922276, Length=244, Percent_Identity=28.2786885245902, Blast_Score=97, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24642557, Length=198, Percent_Identity=32.3232323232323, Blast_Score=86, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584683, Length=778, Percent_Identity=21.9794344473008, Blast_Score=77, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003395
- InterPro:   IPR010935
- InterPro:   IPR011890 [H]

Pfam domain/function: PF06470 SMC_hinge; PF02463 SMC_N [H]

EC number: NA

Molecular weight: Translated: 132208; Mature: 132208

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIKRLDIVGFKSFVDKVSFDFQQGITGIVGPNGCGKSNVVDAIRWAMGEQSAKNLRGRS
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCC
MEDIIFGGSEFRKPLGMAEVSMVFATDDGRVPAKYLSYSEIQITRRLYRDGESEYFLNKT
HHHHHCCCHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
PCRLMDITELFMDTGVGARAYSIIEQGKIGMILHSKPEERRFIIEEAAGVTKFKARKQVA
CHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHH
LKKIDLTRQNLLRIGDILSEIKRQLNSLQRQVKKAERFREYREELREIEIHASVRRFTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAEKERIEGLLREAVSRESTLTADLERRDLELAEHRLALAEREKEVVTAQEGLFRQKADI
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QACESRIEFQRRELSSLERQQERVAVELATAGSQLVAAEEEFARLVEQSGSFAVEVAGEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCH
ESLQTREMELEEMTGAERELAAHLDEARRELFSLLSEIAQLNNQRTAAVRRLEGLAERAD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RNRREGTLLQERLVEATGKVHELDGTVSGLGRTKAELQERLPVVIRREEEIRQRLAEAER
CCCCCHHHHHHHHHHHHCCEEECCCHHHHCCCHHHHHHHCCCCEEECHHHHHHHHHHHHH
EFVTRRDELSRAASRLHSLQELESQFAGYGQGVRNLFLSERFAGRFGGVLADAVETGADY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ETALEAVCAERLQYVLSESDEAALDAIAHLKESGGGRCGIIVAGIPADDRSSVTGATPLL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHH
DRVSIAAAWRPLIEPLLADVHLADTLAQALSLSRQYPRATFVTLQGDLAFGGGIVNGGSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCC
ENAGQGLVHKKREIRELSGTVERLESAVRETETRREELRGERSRLEEEVRDLRQILHQTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQFVNAEKDLQRAREECQRIEERIAIAGIEDEQLQDERRTLDEEIADADGRRAEREAKRE
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ALDAEVARTQEALTVSRRTIEAARDAVTALKVKGAQLREKREAASRATVRTEESIRDLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGRLRGEGESSAAEREHLAVAITAAEDDLKGHLAAYAEAETLSRSLRSEFDARVEAVRV
HHHHHCCCCCCHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EETGLRELRHQCEAARDEVAAHKLTLSGLTLELNHLISSLADKYRLEMREVMPSYADRPF
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEEAAARRQAELGRLIDEIGEVNLTAIEEYRELEERFAFLSSQKDDLEESLQSLQQAIQR
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INRTTRKRFLETFTLVNEKFQEVFPRLFCGGRAELRLTNEEDLLETGIDIIVQPPGKKLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCEEECCCCCCCC
NVTLLSGGEKALTAVALIFSIFLIKPTPFCLLDEVDAPLDDANIGRFNDMVREMSDVSQF
CEEEECCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCEE
IIITHNKATMAVADTLYGVTMEEPGVSKSVSVKLN
EEEECCCCHHHHHHHHHCCEECCCCCCCCEEEEEC
>Mature Secondary Structure
MKIKRLDIVGFKSFVDKVSFDFQQGITGIVGPNGCGKSNVVDAIRWAMGEQSAKNLRGRS
CCCEEEHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCHHHHHHCCCCC
MEDIIFGGSEFRKPLGMAEVSMVFATDDGRVPAKYLSYSEIQITRRLYRDGESEYFLNKT
HHHHHCCCHHHHCCCCHHHEEEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
PCRLMDITELFMDTGVGARAYSIIEQGKIGMILHSKPEERRFIIEEAAGVTKFKARKQVA
CHHHHHHHHHHHHCCCCHHHHHHHHCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHH
LKKIDLTRQNLLRIGDILSEIKRQLNSLQRQVKKAERFREYREELREIEIHASVRRFTAL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DAEKERIEGLLREAVSRESTLTADLERRDLELAEHRLALAEREKEVVTAQEGLFRQKADI
CHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QACESRIEFQRRELSSLERQQERVAVELATAGSQLVAAEEEFARLVEQSGSFAVEVAGEE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCH
ESLQTREMELEEMTGAERELAAHLDEARRELFSLLSEIAQLNNQRTAAVRRLEGLAERAD
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
RNRREGTLLQERLVEATGKVHELDGTVSGLGRTKAELQERLPVVIRREEEIRQRLAEAER
CCCCCHHHHHHHHHHHHCCEEECCCHHHHCCCHHHHHHHCCCCEEECHHHHHHHHHHHHH
EFVTRRDELSRAASRLHSLQELESQFAGYGQGVRNLFLSERFAGRFGGVLADAVETGADY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
ETALEAVCAERLQYVLSESDEAALDAIAHLKESGGGRCGIIVAGIPADDRSSVTGATPLL
HHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCHHH
DRVSIAAAWRPLIEPLLADVHLADTLAQALSLSRQYPRATFVTLQGDLAFGGGIVNGGSA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEECCCCCCCCCC
ENAGQGLVHKKREIRELSGTVERLESAVRETETRREELRGERSRLEEEVRDLRQILHQTE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IQFVNAEKDLQRAREECQRIEERIAIAGIEDEQLQDERRTLDEEIADADGRRAEREAKRE
HHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
ALDAEVARTQEALTVSRRTIEAARDAVTALKVKGAQLREKREAASRATVRTEESIRDLRE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RIGRLRGEGESSAAEREHLAVAITAAEDDLKGHLAAYAEAETLSRSLRSEFDARVEAVRV
HHHHHCCCCCCHHHHHCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EETGLRELRHQCEAARDEVAAHKLTLSGLTLELNHLISSLADKYRLEMREVMPSYADRPF
HHHHHHHHHHHHHHHHHHHHHHHEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DEEAAARRQAELGRLIDEIGEVNLTAIEEYRELEERFAFLSSQKDDLEESLQSLQQAIQR
CHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INRTTRKRFLETFTLVNEKFQEVFPRLFCGGRAELRLTNEEDLLETGIDIIVQPPGKKLQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCHHHHHHCCCCEEECCCCCCCC
NVTLLSGGEKALTAVALIFSIFLIKPTPFCLLDEVDAPLDDANIGRFNDMVREMSDVSQF
CEEEECCCHHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCHHHHHHHHHHHCCEE
IIITHNKATMAVADTLYGVTMEEPGVSKSVSVKLN
EEEECCCCHHHHHHHHHCCEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8654983; 9384377; 7584053; 9701812; 9573042 [H]