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The map label for this gene is allR [H]

Identifier: 39996174

GI number: 39996174

Start: 1161236

End: 1162006

Strand: Reverse

Name: allR [H]

Synonym: GSU1072

Alternate gene names: 39996174

Gene position: 1162006-1161236 (Counterclockwise)

Preceding gene: 39996175

Following gene: 39996173

Centisome position: 30.47

GC content: 60.44

Gene sequence:

>771_bases
ATGACGAGGGAAAAAAGCTCATACGCGGTACAGACCGTTGAAAAGGCCCTCGATATCCTCGAAACGCTCACGGACGAGAG
CCGTCACGCGACCCTTCCCTATCTGGCCGAGAAGCTCGACCTGTCCCGCAACAAGGCATTCCGGCTCCTGGCAACCCTGG
AGAGCAAGGGACTGGTTGAACGGGACGAGACGAGCGGCGTCTATCGCCTGGGCATTTCATCGGTCGAGCTGGCCCAGCGG
CTTCTGAACAGCACCAGCCTCATCCGTCATGCCCACCCAATCATGGAAAGACTGGCGCGCAAGCATGACGAGGCCGTCTA
CATCGCGGTTCTCAAGGGGGACGAGGTTCTTTTCCTGGATATGGTGGACTGTGAGCAGGCCATCAAGACCGCCCCCCTGG
TGGGACGGCGTTTCCCCTTTTTCAGCAACGCCGCCGGCAAAGCCATCCGGGCACTGGAGTCGACCGACCTGCTGGACCGC
TTCCTCAAGAAGCGGGGTCGGAACGGCGGACCGTTTGACCCTGCGGCACTCCAGCAGGAGTTGAAGGCCGTGCGGGAGCA
TGGCGTTGCCGTTGATTTCGACGGATTGGGGGAAGGGATCGTGAGCGTTGCCGTGGCGGTGCGCGACTACGCGGGCAAAG
TCATCGGCGCCTTGACCATGCTGGGGCCCTCCTTCCGGATGATGGCATCCCGCATGGAAAACGAGATTATCCCTTCACTG
CGTGAAGGGGCTGAAATACTCTCCATGAAGTTTGGCTACGCAAAGCTGTGA

Upstream 100 bases:

>100_bases
TGTATTGACGAAATTAAAACACCGTGTTAGCTTTTCAATAAAAATATAACACCGTTTTTCAAACAACCCCGACCACCACA
TTGCGACAGGAAAGGGAACG

Downstream 100 bases:

>100_bases
CCGGAGAACTGCCAGAAAAAACCATGTGCGAAAGGGGGGAGGAGACGTAGAGGATTGCAACGAAAGGCAACGGGAGCGGG
ACGCTGCTCCCTGGGAATGC

Product: IclR family transcriptional regulator

Products: NA

Alternate protein names: Negative regulator of allantoin and glyoxylate utilization operons [H]

Number of amino acids: Translated: 256; Mature: 255

Protein sequence:

>256_residues
MTREKSSYAVQTVEKALDILETLTDESRHATLPYLAEKLDLSRNKAFRLLATLESKGLVERDETSGVYRLGISSVELAQR
LLNSTSLIRHAHPIMERLARKHDEAVYIAVLKGDEVLFLDMVDCEQAIKTAPLVGRRFPFFSNAAGKAIRALESTDLLDR
FLKKRGRNGGPFDPAALQQELKAVREHGVAVDFDGLGEGIVSVAVAVRDYAGKVIGALTMLGPSFRMMASRMENEIIPSL
REGAEILSMKFGYAKL

Sequences:

>Translated_256_residues
MTREKSSYAVQTVEKALDILETLTDESRHATLPYLAEKLDLSRNKAFRLLATLESKGLVERDETSGVYRLGISSVELAQR
LLNSTSLIRHAHPIMERLARKHDEAVYIAVLKGDEVLFLDMVDCEQAIKTAPLVGRRFPFFSNAAGKAIRALESTDLLDR
FLKKRGRNGGPFDPAALQQELKAVREHGVAVDFDGLGEGIVSVAVAVRDYAGKVIGALTMLGPSFRMMASRMENEIIPSL
REGAEILSMKFGYAKL
>Mature_255_residues
TREKSSYAVQTVEKALDILETLTDESRHATLPYLAEKLDLSRNKAFRLLATLESKGLVERDETSGVYRLGISSVELAQRL
LNSTSLIRHAHPIMERLARKHDEAVYIAVLKGDEVLFLDMVDCEQAIKTAPLVGRRFPFFSNAAGKAIRALESTDLLDRF
LKKRGRNGGPFDPAALQQELKAVREHGVAVDFDGLGEGIVSVAVAVRDYAGKVIGALTMLGPSFRMMASRMENEIIPSLR
EGAEILSMKFGYAKL

Specific function: Negative regulator of allantoin and glyoxylate utilization operons. Binds to the gcl promoter and to the allS- allA intergenic region [H]

COG id: COG1414

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 iclR-ED (iclR effector binding) domain [H]

Homologues:

Organism=Escherichia coli, GI1788131, Length=254, Percent_Identity=29.1338582677165, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1786468, Length=254, Percent_Identity=27.1653543307087, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1786715, Length=229, Percent_Identity=25.764192139738, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI87082359, Length=229, Percent_Identity=24.8908296943231, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1789999, Length=265, Percent_Identity=26.0377358490566, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014757
- InterPro:   IPR005471
- InterPro:   IPR011991 [H]

Pfam domain/function: PF09339 HTH_IclR; PF01614 IclR [H]

EC number: NA

Molecular weight: Translated: 28307; Mature: 28176

Theoretical pI: Translated: 8.43; Mature: 8.43

Prosite motif: PS51077 HTH_ICLR ; PS51078 ICLR_ED

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTREKSSYAVQTVEKALDILETLTDESRHATLPYLAEKLDLSRNKAFRLLATLESKGLVE
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
RDETSGVYRLGISSVELAQRLLNSTSLIRHAHPIMERLARKHDEAVYIAVLKGDEVLFLD
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEE
MVDCEQAIKTAPLVGRRFPFFSNAAGKAIRALESTDLLDRFLKKRGRNGGPFDPAALQQE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LKAVREHGVAVDFDGLGEGIVSVAVAVRDYAGKVIGALTMLGPSFRMMASRMENEIIPSL
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
REGAEILSMKFGYAKL
HHHHHHHHHCCCCCCC
>Mature Secondary Structure 
TREKSSYAVQTVEKALDILETLTDESRHATLPYLAEKLDLSRNKAFRLLATLESKGLVE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCCC
RDETSGVYRLGISSVELAQRLLNSTSLIRHAHPIMERLARKHDEAVYIAVLKGDEVLFLD
CCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCEEEEE
MVDCEQAIKTAPLVGRRFPFFSNAAGKAIRALESTDLLDRFLKKRGRNGGPFDPAALQQE
HHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LKAVREHGVAVDFDGLGEGIVSVAVAVRDYAGKVIGALTMLGPSFRMMASRMENEIIPSL
HHHHHHCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHH
REGAEILSMKFGYAKL
HHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA