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The map label for this gene is yhdR [H]

Identifier: 39996163

GI number: 39996163

Start: 1147172

End: 1148368

Strand: Reverse

Name: yhdR [H]

Synonym: GSU1061

Alternate gene names: 39996163

Gene position: 1148368-1147172 (Counterclockwise)

Preceding gene: 39996169

Following gene: 39996162

Centisome position: 30.11

GC content: 63.74

Gene sequence:

>1197_bases
ATGCCTATCGCCACGAAAATCGCCGGCCACATTTCCAAGTCGTCATGGATTCGCAAGATGTTCGAGGAGGGGGAGCGACT
GCGGCAGATCCACGGCGCCGACAATGTGTACGATTTCACCATCGGCAACCCCGACACGGAGCCACCCGAGCAGTTCCGGG
AAGAACTCCTCAACCTGGCTCGGCACCCCGTGCCCGGCATGCACCGCTACATGAGCAACGCCGGCTATGCGGAAACCCGC
GGTGCCGTGGCCGAAGTTCTTTCCGAGGCGGCAGGCTTCGAGGTGAAGGCCGACCACGTCATCATGACCTGTGGGGCCGG
CGGCGCCCTCAACGTGGTCCTGAAGACTATTCTCAACCCGGGGGAAGAGGTGATCATCCTGGCCCCCTACTTCGTGGAAT
ATAAATTCTACATCGATAACCACGGCGGCGTGCCACGGGAGGTCTGGACCGACCGCGAGACCTTCCAGCTCGACGTGGCG
GCCATCGAGGCGGCCATGACCGCCAAGACCCGGGCGATCATCATCTGCTCGCCCAACAACCCCACCGGCGTCATTTATCC
TGAAGAGAGCCTGGCGGCTCTGGGCGAGATGGTGGCACGGATGGAGCGGCGCTTCGACCGCCAGATCTACGTTATCTCCG
ACGAGCCCTATGCCCGCATCAGCTACGACGGCAAGCAGGTGCCGAACATCTTCCGGTTTGTGCAGAGCTCTGTCATCGTC
ACCTCCCACAGCAAGGACCTGGCCCTGCCCGGCGAGCGGATCGGCTATCTGGCGGCCAATCCCCGCGCCCGCGGCGTGGA
ACAGTTCATGGAAGGGGCGGTCTTCTCCAACCGGGTGCTCGGTTTTGTGAATGCGCCGGCCCTCATGCAGCGGCTCGTGG
CCAAGCTGCAGCGGTCCTCCGTGGACATCGGCGAGTACCAGGCCAAGCGAGACCTGTTCTACGACAGCCTCACCGCCATG
GGGTTCCGGATGGTGAAGCCCGACGGCGCCTTCTACCTCTTTCCCCAATCGCCGCTGGCAGATGATGTGGCATTCGTCAC
CATGGCCCAGAAACACCGCATTCTGCTCGTCCCCGGTGCCGGATTCGGCGCACCCGGCTTCTTCAGGATCGCCTACTGCG
TGGATCGGGGCGTCATCGAACGGAGTCTGCCCGCATGGCGGGAGCTGGCCCGCGACGCAGGCCTGGGCGGGAGCTGA

Upstream 100 bases:

>100_bases
AACAGGCAAACGCATGAGCACTCCCGTCAATCCCCCCTCTTGCCCTTCCCCCTCCCCTGTGTTACAAGCTGATATACATT
ATTTTCCACAGAGGTTCGCC

Downstream 100 bases:

>100_bases
CGATCGGCAACAATTTTAATTTTCAAAATCACAGCATTATCGATTCAAATCAATAACATTTGAAACTTGACTTTTCGAAT
TGAAATGCGCTAAGGTCAGC

Product: aspartate aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MPIATKIAGHISKSSWIRKMFEEGERLRQIHGADNVYDFTIGNPDTEPPEQFREELLNLARHPVPGMHRYMSNAGYAETR
GAVAEVLSEAAGFEVKADHVIMTCGAGGALNVVLKTILNPGEEVIILAPYFVEYKFYIDNHGGVPREVWTDRETFQLDVA
AIEAAMTAKTRAIIICSPNNPTGVIYPEESLAALGEMVARMERRFDRQIYVISDEPYARISYDGKQVPNIFRFVQSSVIV
TSHSKDLALPGERIGYLAANPRARGVEQFMEGAVFSNRVLGFVNAPALMQRLVAKLQRSSVDIGEYQAKRDLFYDSLTAM
GFRMVKPDGAFYLFPQSPLADDVAFVTMAQKHRILLVPGAGFGAPGFFRIAYCVDRGVIERSLPAWRELARDAGLGGS

Sequences:

>Translated_398_residues
MPIATKIAGHISKSSWIRKMFEEGERLRQIHGADNVYDFTIGNPDTEPPEQFREELLNLARHPVPGMHRYMSNAGYAETR
GAVAEVLSEAAGFEVKADHVIMTCGAGGALNVVLKTILNPGEEVIILAPYFVEYKFYIDNHGGVPREVWTDRETFQLDVA
AIEAAMTAKTRAIIICSPNNPTGVIYPEESLAALGEMVARMERRFDRQIYVISDEPYARISYDGKQVPNIFRFVQSSVIV
TSHSKDLALPGERIGYLAANPRARGVEQFMEGAVFSNRVLGFVNAPALMQRLVAKLQRSSVDIGEYQAKRDLFYDSLTAM
GFRMVKPDGAFYLFPQSPLADDVAFVTMAQKHRILLVPGAGFGAPGFFRIAYCVDRGVIERSLPAWRELARDAGLGGS
>Mature_397_residues
PIATKIAGHISKSSWIRKMFEEGERLRQIHGADNVYDFTIGNPDTEPPEQFREELLNLARHPVPGMHRYMSNAGYAETRG
AVAEVLSEAAGFEVKADHVIMTCGAGGALNVVLKTILNPGEEVIILAPYFVEYKFYIDNHGGVPREVWTDRETFQLDVAA
IEAAMTAKTRAIIICSPNNPTGVIYPEESLAALGEMVARMERRFDRQIYVISDEPYARISYDGKQVPNIFRFVQSSVIVT
SHSKDLALPGERIGYLAANPRARGVEQFMEGAVFSNRVLGFVNAPALMQRLVAKLQRSSVDIGEYQAKRDLFYDSLTAMG
FRMVKPDGAFYLFPQSPLADDVAFVTMAQKHRILLVPGAGFGAPGFFRIAYCVDRGVIERSLPAWRELARDAGLGGS

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI56713256, Length=358, Percent_Identity=22.0670391061453, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI56713254, Length=358, Percent_Identity=22.0670391061453, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI95147551, Length=322, Percent_Identity=24.223602484472, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI169881279, Length=322, Percent_Identity=24.223602484472, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI4507369, Length=328, Percent_Identity=23.780487804878, Blast_Score=82, Evalue=7e-16,
Organism=Escherichia coli, GI1786816, Length=363, Percent_Identity=26.4462809917355, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1788627, Length=381, Percent_Identity=25.4593175853018, Blast_Score=95, Evalue=9e-21,
Organism=Escherichia coli, GI1788722, Length=382, Percent_Identity=23.8219895287958, Blast_Score=77, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17567663, Length=354, Percent_Identity=25.4237288135593, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71994472, Length=364, Percent_Identity=23.9010989010989, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI71994476, Length=364, Percent_Identity=23.9010989010989, Blast_Score=89, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17567369, Length=322, Percent_Identity=24.5341614906832, Blast_Score=85, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6322401, Length=295, Percent_Identity=25.7627118644068, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI28573069, Length=340, Percent_Identity=25.8823529411765, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI24646114, Length=340, Percent_Identity=25.8823529411765, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573067, Length=340, Percent_Identity=25.8823529411765, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI28573065, Length=340, Percent_Identity=25.8823529411765, Blast_Score=101, Evalue=8e-22,
Organism=Drosophila melanogaster, GI18859735, Length=371, Percent_Identity=23.1805929919137, Blast_Score=85, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 44086; Mature: 43955

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPIATKIAGHISKSSWIRKMFEEGERLRQIHGADNVYDFTIGNPDTEPPEQFREELLNLA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RHPVPGMHRYMSNAGYAETRGAVAEVLSEAAGFEVKADHVIMTCGAGGALNVVLKTILNP
HCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCEEEEEECCCCHHHHHHHHHHCC
GEEVIILAPYFVEYKFYIDNHGGVPREVWTDRETFQLDVAAIEAAMTAKTRAIIICSPNN
CCCEEEEEEEEEEEEEEEECCCCCCHHHHCCCCCEEEHHHHHHHHHHCCCEEEEEECCCC
PTGVIYPEESLAALGEMVARMERRFDRQIYVISDEPYARISYDGKQVPNIFRFVQSSVIV
CCEEEECHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCEEE
TSHSKDLALPGERIGYLAANPRARGVEQFMEGAVFSNRVLGFVNAPALMQRLVAKLQRSS
EECCCCCCCCHHHCEEEECCCCHHHHHHHHHCHHHHCCCEEEECCHHHHHHHHHHHHHCC
VDIGEYQAKRDLFYDSLTAMGFRMVKPDGAFYLFPQSPLADDVAFVTMAQKHRILLVPGA
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCCHHHHEEECCCCEEEEEECC
GFGAPGFFRIAYCVDRGVIERSLPAWRELARDAGLGGS
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC
>Mature Secondary Structure 
PIATKIAGHISKSSWIRKMFEEGERLRQIHGADNVYDFTIGNPDTEPPEQFREELLNLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHHH
RHPVPGMHRYMSNAGYAETRGAVAEVLSEAAGFEVKADHVIMTCGAGGALNVVLKTILNP
HCCCCHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCEEEEEECCCCHHHHHHHHHHCC
GEEVIILAPYFVEYKFYIDNHGGVPREVWTDRETFQLDVAAIEAAMTAKTRAIIICSPNN
CCCEEEEEEEEEEEEEEEECCCCCCHHHHCCCCCEEEHHHHHHHHHHCCCEEEEEECCCC
PTGVIYPEESLAALGEMVARMERRFDRQIYVISDEPYARISYDGKQVPNIFRFVQSSVIV
CCEEEECHHHHHHHHHHHHHHHHHHCCEEEEECCCCCEEEECCCCHHHHHHHHHHHCEEE
TSHSKDLALPGERIGYLAANPRARGVEQFMEGAVFSNRVLGFVNAPALMQRLVAKLQRSS
EECCCCCCCCHHHCEEEECCCCHHHHHHHHHCHHHHCCCEEEECCHHHHHHHHHHHHHCC
VDIGEYQAKRDLFYDSLTAMGFRMVKPDGAFYLFPQSPLADDVAFVTMAQKHRILLVPGA
CCHHHHHHHHHHHHHHHHHCCEEEECCCCCEEECCCCCCCCHHHHEEECCCCEEEEEECC
GFGAPGFFRIAYCVDRGVIERSLPAWRELARDAGLGGS
CCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]