Click here to switch to the map view.

The map label for this gene is aphA [H]

Identifier: 39996152

GI number: 39996152

Start: 1137432

End: 1138790

Strand: Direct

Name: aphA [H]

Synonym: GSU1050

Alternate gene names: 39996152

Gene position: 1137432-1138790 (Clockwise)

Preceding gene: 39996150

Following gene: 39996153

Centisome position: 29.82

GC content: 62.55

Gene sequence:

>1359_bases
GTGAAAACAATGAGTGACCCGCCTAAAAACGGTATTGAATCGATCATCGTCACGACCCTCGTGGCGCTTACGGCCTTCTG
GTTCGCCGACACGGTGATCGATGCCGTCATTCCCCAGATGGGATGTGAATGCGGCCTCCTTCACGCTCCGACCGTGCGTG
CCTCTCTGTTCCACCTGATCCCCCTCATTGCGCAACTGCTGCTCATTTTCTTCGTCCGCAGACTGTTCAGGGAGCGCCGG
CTGCTGGTCCGGAAGCTGGAAGCGGCGGTGGCCACTACCCTGGATGAAAAGGCCAGGACCGATGCCGTCATTGCCGCGGT
CGGCGACGGAGTCTGCATGCTCGACCGGGGTTTCCGCATCGTCTACCAGAACCGGGCCCATGAGCGCCTGCTCGGCGAGC
ACGGTGGAGAACGCTGCTCCGACGCATACGGCGAAGACCCGGATGCCTGCCGTGACTGTCCCATGGCCCGCGCCATGGAT
ACGGGCGAGGTATGCACGGGAAGCCGCCGGTTCATCAGCAAGGGGGAGACGCGTCTTCTGGAGATCACCTCCTCGCCGGT
GCGCAATGCCGCCGGTGAAATCGTCGCCGGCGTCGAGGTGGTTCGCGATGTGACCGAGCGCAGGCGCAGCGAGGAGGAAA
TCAAGTCCCTCAATGCCGCCTTGGAGCGCCGCGCCAGGGATCTGGCAGCCAATAACCGGGAGTTGGAGGCGTTCAGCCAT
TCTCTCTCCCACGATCTGAGCGCCCCGCTCGCCAAGATATCCTGCGCTGTTGAGACGCTGCGGGAAACCTACGGCGAGCA
AATGGGCGACGACGGTCGGTTCCTGTTGTCGTGTATCTGCGAAGGGAGTTCCCAGATGGATGACCTCATGGAAGCCCTCC
TTGCCTTGAACCAGGTTTCGCGAAAAGACCTCCGCCGTGAAAAAGTCGACATGGGAGCACTAGTCAGCCAGCTCGCTCTG
GACCTGCGCCGGTCGGAGCCGGCCCGCCGGATCGATTTTGTCATTGCCCCCGATCTGACGGCCGAGGGGGACCCCTCAAT
GCTCCGTGTGGCCTTGCAGAACCTGCTGTCCAATGCCTGGAAATTCACCCGGAACGTGGATGGCGGCCGGATAGAATTCG
GCTCCGTTGACCGCAACGGCGAACGAGTCTTTTATCTTCGCGACAATGGCGCCGGTTTTGACATGAGGCAAGTGGGACGG
ATATTCGAGGTGTTCCAGCGGCTCCACGACGAGAGCCTGTTCCCGGGCACCGGAGTGGGGCTCGCCACCGTACAACGGGT
CATCGAGCGGCACGGCGGCACCGTTACCGCCCACGGCGTGCCGGGCCATGGGGCAACCTTCACCTTCACCCTGCCGTAG

Upstream 100 bases:

>100_bases
AAATTAACGTATTTTGATTTTTGATTGTATGGTGGCGCAACTGGCGGAATGTTAATGTAGTTTTAGAGATGACTCCCCGC
AGGGACGCGAGGTCTTATCC

Downstream 100 bases:

>100_bases
CCGGCGTTCCCTTGTCCGGGCGAGACGACGGACGCCCGGCCCTCCGATCGCCTGCATTTTGTGTGTGCAAATGTGGCGGT
TGTGGTAGTTTTACTTTACC

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MKTMSDPPKNGIESIIVTTLVALTAFWFADTVIDAVIPQMGCECGLLHAPTVRASLFHLIPLIAQLLLIFFVRRLFRERR
LLVRKLEAAVATTLDEKARTDAVIAAVGDGVCMLDRGFRIVYQNRAHERLLGEHGGERCSDAYGEDPDACRDCPMARAMD
TGEVCTGSRRFISKGETRLLEITSSPVRNAAGEIVAGVEVVRDVTERRRSEEEIKSLNAALERRARDLAANNRELEAFSH
SLSHDLSAPLAKISCAVETLRETYGEQMGDDGRFLLSCICEGSSQMDDLMEALLALNQVSRKDLRREKVDMGALVSQLAL
DLRRSEPARRIDFVIAPDLTAEGDPSMLRVALQNLLSNAWKFTRNVDGGRIEFGSVDRNGERVFYLRDNGAGFDMRQVGR
IFEVFQRLHDESLFPGTGVGLATVQRVIERHGGTVTAHGVPGHGATFTFTLP

Sequences:

>Translated_452_residues
MKTMSDPPKNGIESIIVTTLVALTAFWFADTVIDAVIPQMGCECGLLHAPTVRASLFHLIPLIAQLLLIFFVRRLFRERR
LLVRKLEAAVATTLDEKARTDAVIAAVGDGVCMLDRGFRIVYQNRAHERLLGEHGGERCSDAYGEDPDACRDCPMARAMD
TGEVCTGSRRFISKGETRLLEITSSPVRNAAGEIVAGVEVVRDVTERRRSEEEIKSLNAALERRARDLAANNRELEAFSH
SLSHDLSAPLAKISCAVETLRETYGEQMGDDGRFLLSCICEGSSQMDDLMEALLALNQVSRKDLRREKVDMGALVSQLAL
DLRRSEPARRIDFVIAPDLTAEGDPSMLRVALQNLLSNAWKFTRNVDGGRIEFGSVDRNGERVFYLRDNGAGFDMRQVGR
IFEVFQRLHDESLFPGTGVGLATVQRVIERHGGTVTAHGVPGHGATFTFTLP
>Mature_452_residues
MKTMSDPPKNGIESIIVTTLVALTAFWFADTVIDAVIPQMGCECGLLHAPTVRASLFHLIPLIAQLLLIFFVRRLFRERR
LLVRKLEAAVATTLDEKARTDAVIAAVGDGVCMLDRGFRIVYQNRAHERLLGEHGGERCSDAYGEDPDACRDCPMARAMD
TGEVCTGSRRFISKGETRLLEITSSPVRNAAGEIVAGVEVVRDVTERRRSEEEIKSLNAALERRARDLAANNRELEAFSH
SLSHDLSAPLAKISCAVETLRETYGEQMGDDGRFLLSCICEGSSQMDDLMEALLALNQVSRKDLRREKVDMGALVSQLAL
DLRRSEPARRIDFVIAPDLTAEGDPSMLRVALQNLLSNAWKFTRNVDGGRIEFGSVDRNGERVFYLRDNGAGFDMRQVGR
IFEVFQRLHDESLFPGTGVGLATVQRVIERHGGTVTAHGVPGHGATFTFTLP

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=363, Percent_Identity=24.5179063360882, Blast_Score=99, Evalue=8e-22,
Organism=Escherichia coli, GI48994928, Length=350, Percent_Identity=25.1428571428571, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI145693157, Length=265, Percent_Identity=26.4150943396226, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786912, Length=239, Percent_Identity=28.8702928870293, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=28.6307053941909, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=274, Percent_Identity=25.1824817518248, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1786600, Length=220, Percent_Identity=26.3636363636364, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=24.4094488188976, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI1789149, Length=263, Percent_Identity=25.4752851711027, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 49942; Mature: 49942

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: PS50113 PAC ; PS00070 ALDEHYDE_DEHYDR_CYS ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTMSDPPKNGIESIIVTTLVALTAFWFADTVIDAVIPQMGCECGLLHAPTVRASLFHLI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
PLIAQLLLIFFVRRLFRERRLLVRKLEAAVATTLDEKARTDAVIAAVGDGVCMLDRGFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCEE
VYQNRAHERLLGEHGGERCSDAYGEDPDACRDCPMARAMDTGEVCTGSRRFISKGETRLL
EECCCHHHHHHHHCCCCHHHHCCCCCCHHHHCCCHHHCCCCCCCCCCCHHHHHCCCCEEE
EITSSPVRNAAGEIVAGVEVVRDVTERRRSEEEIKSLNAALERRARDLAANNRELEAFSH
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SLSHDLSAPLAKISCAVETLRETYGEQMGDDGRFLLSCICEGSSQMDDLMEALLALNQVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RKDLRREKVDMGALVSQLALDLRRSEPARRIDFVIAPDLTAEGDPSMLRVALQNLLSNAW
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KFTRNVDGGRIEFGSVDRNGERVFYLRDNGAGFDMRQVGRIFEVFQRLHDESLFPGTGVG
HHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCH
LATVQRVIERHGGTVTAHGVPGHGATFTFTLP
HHHHHHHHHHCCCEEEECCCCCCCCEEEEECC
>Mature Secondary Structure
MKTMSDPPKNGIESIIVTTLVALTAFWFADTVIDAVIPQMGCECGLLHAPTVRASLFHLI
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
PLIAQLLLIFFVRRLFRERRLLVRKLEAAVATTLDEKARTDAVIAAVGDGVCMLDRGFRI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCEEEECCCCEE
VYQNRAHERLLGEHGGERCSDAYGEDPDACRDCPMARAMDTGEVCTGSRRFISKGETRLL
EECCCHHHHHHHHCCCCHHHHCCCCCCHHHHCCCHHHCCCCCCCCCCCHHHHHCCCCEEE
EITSSPVRNAAGEIVAGVEVVRDVTERRRSEEEIKSLNAALERRARDLAANNRELEAFSH
EECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
SLSHDLSAPLAKISCAVETLRETYGEQMGDDGRFLLSCICEGSSQMDDLMEALLALNQVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RKDLRREKVDMGALVSQLALDLRRSEPARRIDFVIAPDLTAEGDPSMLRVALQNLLSNAW
HHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
KFTRNVDGGRIEFGSVDRNGERVFYLRDNGAGFDMRQVGRIFEVFQRLHDESLFPGTGVG
HHHCCCCCCEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCH
LATVQRVIERHGGTVTAHGVPGHGATFTFTLP
HHHHHHHHHHCCCEEEECCCCCCCCEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]