Click here to switch to the map view.

The map label for this gene is galU [H]

Identifier: 39995965

GI number: 39995965

Start: 918502

End: 919371

Strand: Reverse

Name: galU [H]

Synonym: GSU0859

Alternate gene names: 39995965

Gene position: 919371-918502 (Counterclockwise)

Preceding gene: 39995966

Following gene: 39995962

Centisome position: 24.1

GC content: 60.8

Gene sequence:

>870_bases
ATGCAGGTAAAAAAAGCGGTATTCCCGGTGGCGGGACTCGGTACCCGGTTTCTTCCGGCAACCAAATCATCTCCCAAGGA
GATGCTCCCCCTGATCGACAAGCCGCTGGTCCAATACGTGGTGGAGGAGGCGGTTGCCTCGGGCATCGAGCAGCTCCTCT
TTGTGACCGGTCGGAGCAAGCGGGCCATTGAGGATCACTTCGACATCTCCTTCGAGCTGGAAGCGCTGCTCCAGGAAAAG
GGGAAGGATGACATGCTCCAGGAGGTGCGGGAGATTGCCGACATGGTGAAGATTTTCTATGTCCGGCAGAAACAGGCCCT
GGGACTCGGCCACGCCATCCTCTGCGCCAGGGAATTCGTGGGCGACGAACCCTTCGCGGTCCTGCTGGGGGACGACATCA
TCGACGCGGAACAACCCTGCCTGGGCCAGCTCCTGGATGTCTACCGTAAATACCGGGGTCCGGTCGTGGCCCTGGAAAAG
GTGCCCATCGAGGCCATCTCCTCCTACGGCTGCGTGAAGGCAACGGGAATAACCGACCGGATCTTCGAGGTGACTGACCT
GGTGGAAAAACCTCGCCGCGAGGAGGCCCCTTCGGACATGGCCATCATCGGTCGTTACGTCCTTACCCCCGACATCTTTC
CCATCCTGGAACGCCAGACCCCCGGCAAGGGGGGTGAAATCCAGCTCACCGACGCCCTGCTCACCCTGTCGCGGGAAGAG
GCCATTTACGGCTGCCTGTTCAAGGGAAAGCGCCACGACTGCGGCGACAAGCTCGGCTTCCTGAAAGCCACGGTGGACAT
GGCCCTCAAACGGGAGGAGTTCAACGAAGAGTTCCGGGACTATCTGCGGGAAGTGCTGGCCAGGGGCTGA

Upstream 100 bases:

>100_bases
CACATCATGGCCATGGGGCGGGAGGACCTGGTCCCCGCCATCGTTGCCGGTGTGGAACGGGACAGTCAGGAACACACTAC
GATCTGAAAGGAGTCGGATC

Downstream 100 bases:

>100_bases
AAACAGGTATAAAGGGGATGGCCGGACTGCGCCGGCGTCAGCGGAGCGAACGGCTGGCGCCCCGCACGATGCCGTACTGG
AAAAAGGCGACCAGGTGGAA

Product: UTP-glucose-1-phosphate uridylyltransferase

Products: NA

Alternate protein names: Alpha-D-glucosyl-1-phosphate uridylyltransferase; UDP-glucose pyrophosphorylase; UDPGP; Uridine diphosphoglucose pyrophosphorylase [H]

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MQVKKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQLLFVTGRSKRAIEDHFDISFELEALLQEK
GKDDMLQEVREIADMVKIFYVRQKQALGLGHAILCAREFVGDEPFAVLLGDDIIDAEQPCLGQLLDVYRKYRGPVVALEK
VPIEAISSYGCVKATGITDRIFEVTDLVEKPRREEAPSDMAIIGRYVLTPDIFPILERQTPGKGGEIQLTDALLTLSREE
AIYGCLFKGKRHDCGDKLGFLKATVDMALKREEFNEEFRDYLREVLARG

Sequences:

>Translated_289_residues
MQVKKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQLLFVTGRSKRAIEDHFDISFELEALLQEK
GKDDMLQEVREIADMVKIFYVRQKQALGLGHAILCAREFVGDEPFAVLLGDDIIDAEQPCLGQLLDVYRKYRGPVVALEK
VPIEAISSYGCVKATGITDRIFEVTDLVEKPRREEAPSDMAIIGRYVLTPDIFPILERQTPGKGGEIQLTDALLTLSREE
AIYGCLFKGKRHDCGDKLGFLKATVDMALKREEFNEEFRDYLREVLARG
>Mature_289_residues
MQVKKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQLLFVTGRSKRAIEDHFDISFELEALLQEK
GKDDMLQEVREIADMVKIFYVRQKQALGLGHAILCAREFVGDEPFAVLLGDDIIDAEQPCLGQLLDVYRKYRGPVVALEK
VPIEAISSYGCVKATGITDRIFEVTDLVEKPRREEAPSDMAIIGRYVLTPDIFPILERQTPGKGGEIQLTDALLTLSREE
AIYGCLFKGKRHDCGDKLGFLKATVDMALKREEFNEEFRDYLREVLARG

Specific function: Catalyzes the formation of UDP-glucose from glucose-1- phosphate and UTP. This is an intermediate step in the biosynthesis of diglucosyl-diacylglycerol (Glc2-DAG) [H]

COG id: COG1210

COG function: function code M; UDP-glucose pyrophosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDPGP type 2 family [H]

Homologues:

Organism=Escherichia coli, GI1787488, Length=290, Percent_Identity=47.9310344827586, Blast_Score=264, Evalue=6e-72,
Organism=Escherichia coli, GI1788355, Length=294, Percent_Identity=42.5170068027211, Blast_Score=229, Evalue=2e-61,
Organism=Escherichia coli, GI1790224, Length=232, Percent_Identity=24.5689655172414, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 260 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005771
- InterPro:   IPR005835 [H]

Pfam domain/function: PF00483 NTP_transferase [H]

EC number: =2.7.7.9 [H]

Molecular weight: Translated: 32380; Mature: 32380

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVKKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQLLFVTGRSK
CCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RAIEDHFDISFELEALLQEKGKDDMLQEVREIADMVKIFYVRQKQALGLGHAILCAREFV
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GDEPFAVLLGDDIIDAEQPCLGQLLDVYRKYRGPVVALEKVPIEAISSYGCVKATGITDR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHCCHHHHHCCCCEEECCCHHH
IFEVTDLVEKPRREEAPSDMAIIGRYVLTPDIFPILERQTPGKGGEIQLTDALLTLSREE
HHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEHHHHHHHHHHH
AIYGCLFKGKRHDCGDKLGFLKATVDMALKREEFNEEFRDYLREVLARG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQVKKAVFPVAGLGTRFLPATKSSPKEMLPLIDKPLVQYVVEEAVASGIEQLLFVTGRSK
CCCHHHHCCHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
RAIEDHFDISFELEALLQEKGKDDMLQEVREIADMVKIFYVRQKQALGLGHAILCAREFV
HHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GDEPFAVLLGDDIIDAEQPCLGQLLDVYRKYRGPVVALEKVPIEAISSYGCVKATGITDR
CCCCEEEEECCCCCCCCCHHHHHHHHHHHHHCCCEEEEHHCCHHHHHCCCCEEECCCHHH
IFEVTDLVEKPRREEAPSDMAIIGRYVLTPDIFPILERQTPGKGGEIQLTDALLTLSREE
HHHHHHHHHCCHHHCCCCCHHHHHHHHHCCCHHHHHHCCCCCCCCEEEEHHHHHHHHHHH
AIYGCLFKGKRHDCGDKLGFLKATVDMALKREEFNEEFRDYLREVLARG
HHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]