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The map label for this gene is tsr [C]

Identifier: 39995856

GI number: 39995856

Start: 793255

End: 794874

Strand: Reverse

Name: tsr [C]

Synonym: GSU0750

Alternate gene names: 39995856

Gene position: 794874-793255 (Counterclockwise)

Preceding gene: 39995858

Following gene: 39995855

Centisome position: 20.84

GC content: 65.06

Gene sequence:

>1620_bases
ATGAGTGTAAGTATCGGCAGACGGCTAACCCTCAACATGGTCTGGGGGGTGTTTGTGGTTCTGGTGCTGGTGATCGGCAA
CTGGATCGGCATGGGCCATCTGGAGCAGCTGCAAGCGACCAGTCACGAGGCCATGGCGCGCAGCAGGTCCGCCCAGGAGA
CCAAGGTGATCGGCGAAAAACTGTACCGGTTCGTCCTGGAATCGGTCGCCAACCCCGACATGGCCGGCTCCTCGTCCAAG
GGATGGCTGAACCGGAAGGCGGAGGGAATGGCCAAGCTGAAGCAGCTGGCCGAGCAGACCGGGGACGACGCTGCCCTGGG
CGCCCTGGTAGCCTCGGCGGACAAGGCGTTCCGGGGCACGGTTACCCTCTATGAAACCAAATTGATCCCGGCGCTCGAAC
GAGGGGCGAACCACGAGGATATCATGGACATCGACGATGAGATCTCCATGGAGTCCGACAACCTGAGCATCAGCCTGCTC
AAGGTCGCCGAAACGCTGGAAAAACGGGCCATTGCCGCAAGCGCCCAGTACGACTCCTTCAGCGCAAAACTCAAGACCTT
CTCCCTTGCCCTGGGTGGCATCGGCATCGTGCTGCTGGTGGTGTTCTCCTCCTGGCTCAGCCGTTCGATCATGAGGCCGC
TCCGTCAGGTCATCGCCATGATGGAAGACGTGGCCGAGGGCGAGGGGGATCTGACCAAGCGCCTCGAACACCGGAGCAAC
GACGAGTTGGGGAAACTCTGCACCGAGTTCAACTCCTTCGTGGGCAAAGTCCACGACACCATCTCCCGGACCTCCAGCGT
GGCTCGGGACGTGACCGGATCGGTGGCAGAGATCAGCCGGACCGCCGAGCGGTTGGCCGAGGGCGCCGAAGAGGTCGCCT
CCCAGGCGGTCATGGCGGCCACGGCGAGCGAGGAGATGGCCGCCACCTCCTGCGAGATTGCCGGCAACTGCCAGACCGCG
GCCCAGTCGTCGAGCCGGGCGCGGGAAACGGCTGCCCGGGGCTTTGCCATGGTGGAAAACACCATTGCGGTCATGAACCA
GATCGCCCGGCGGGTCAGGGTGTCGGCCGAATCGGTGCAGGGGCTCGGCGCCCGCTCCGACCAGATCGGCGAAATCGTCA
TGACCATTCAGGACATCGCGGACCAGACGAACCTGCTGGCGCTCAACGCTGCCATCGAGGCGGCCAGGGCCGGCGAACAG
GGGCGCGGCTTCGCCGTGGTGGCCGACGAGGTGCGGGCACTGGCGGAGCGGACATCACGGGCTACCCGCGAGATCGGCGA
GATGATCAAGGGCATCCAGGGCGAAACCCGGACTGCGGTGCTCACCATGGAAGAAGGCGTCAAGGAAGTCGAAGCGGGCA
CCCGGGAGGCCGCCAAGTCGGGCGAGGCGCTCAATGAGATCATGCAGGGGATCGAGCAGCTCAACCAGCAGATGGGCCAG
ATCGCCTGCGCCGCGGAGCAGCAGACCTCCACGACCATGGAAATCAGCGGCAGCATCCAGCGCATCAAGGACGTCGCCCA
GGAGACCGCCGGCGGCGCCCACGACAGCGCCCGGACCTCCACCCGGCTCACGGACCTGTCCCACGACCTGGATCGCCTGG
TGAGCCAGTTCAGGGTGTGA

Upstream 100 bases:

>100_bases
AAAATATCACTAGGATTGCCACCTGTCCCGGAGTCCACGTTCCGTGCCGCACGCCGGCATTCGGCAAGACGGGCGGCAGC
ATGAACAAAGGAGCGCATCG

Downstream 100 bases:

>100_bases
CCGGTCGACGATGCATACGAAATGGAACGGGCGGTGCCACAACGGCATCGCCCGTTTTGTTTGCTCCTTCCCTGCCTCCC
TTCTCCCCCGGCACAGATGG

Product: methyl-accepting chemotaxis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 539; Mature: 538

Protein sequence:

>539_residues
MSVSIGRRLTLNMVWGVFVVLVLVIGNWIGMGHLEQLQATSHEAMARSRSAQETKVIGEKLYRFVLESVANPDMAGSSSK
GWLNRKAEGMAKLKQLAEQTGDDAALGALVASADKAFRGTVTLYETKLIPALERGANHEDIMDIDDEISMESDNLSISLL
KVAETLEKRAIAASAQYDSFSAKLKTFSLALGGIGIVLLVVFSSWLSRSIMRPLRQVIAMMEDVAEGEGDLTKRLEHRSN
DELGKLCTEFNSFVGKVHDTISRTSSVARDVTGSVAEISRTAERLAEGAEEVASQAVMAATASEEMAATSCEIAGNCQTA
AQSSSRARETAARGFAMVENTIAVMNQIARRVRVSAESVQGLGARSDQIGEIVMTIQDIADQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAERTSRATREIGEMIKGIQGETRTAVLTMEEGVKEVEAGTREAAKSGEALNEIMQGIEQLNQQMGQ
IACAAEQQTSTTMEISGSIQRIKDVAQETAGGAHDSARTSTRLTDLSHDLDRLVSQFRV

Sequences:

>Translated_539_residues
MSVSIGRRLTLNMVWGVFVVLVLVIGNWIGMGHLEQLQATSHEAMARSRSAQETKVIGEKLYRFVLESVANPDMAGSSSK
GWLNRKAEGMAKLKQLAEQTGDDAALGALVASADKAFRGTVTLYETKLIPALERGANHEDIMDIDDEISMESDNLSISLL
KVAETLEKRAIAASAQYDSFSAKLKTFSLALGGIGIVLLVVFSSWLSRSIMRPLRQVIAMMEDVAEGEGDLTKRLEHRSN
DELGKLCTEFNSFVGKVHDTISRTSSVARDVTGSVAEISRTAERLAEGAEEVASQAVMAATASEEMAATSCEIAGNCQTA
AQSSSRARETAARGFAMVENTIAVMNQIARRVRVSAESVQGLGARSDQIGEIVMTIQDIADQTNLLALNAAIEAARAGEQ
GRGFAVVADEVRALAERTSRATREIGEMIKGIQGETRTAVLTMEEGVKEVEAGTREAAKSGEALNEIMQGIEQLNQQMGQ
IACAAEQQTSTTMEISGSIQRIKDVAQETAGGAHDSARTSTRLTDLSHDLDRLVSQFRV
>Mature_538_residues
SVSIGRRLTLNMVWGVFVVLVLVIGNWIGMGHLEQLQATSHEAMARSRSAQETKVIGEKLYRFVLESVANPDMAGSSSKG
WLNRKAEGMAKLKQLAEQTGDDAALGALVASADKAFRGTVTLYETKLIPALERGANHEDIMDIDDEISMESDNLSISLLK
VAETLEKRAIAASAQYDSFSAKLKTFSLALGGIGIVLLVVFSSWLSRSIMRPLRQVIAMMEDVAEGEGDLTKRLEHRSND
ELGKLCTEFNSFVGKVHDTISRTSSVARDVTGSVAEISRTAERLAEGAEEVASQAVMAATASEEMAATSCEIAGNCQTAA
QSSSRARETAARGFAMVENTIAVMNQIARRVRVSAESVQGLGARSDQIGEIVMTIQDIADQTNLLALNAAIEAARAGEQG
RGFAVVADEVRALAERTSRATREIGEMIKGIQGETRTAVLTMEEGVKEVEAGTREAAKSGEALNEIMQGIEQLNQQMGQI
ACAAEQQTSTTMEISGSIQRIKDVAQETAGGAHDSARTSTRLTDLSHDLDRLVSQFRV

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=341, Percent_Identity=31.0850439882698, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI1788195, Length=308, Percent_Identity=31.1688311688312, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1787690, Length=353, Percent_Identity=30.3116147308782, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1788194, Length=345, Percent_Identity=28.9855072463768, Blast_Score=122, Evalue=8e-29,
Organism=Escherichia coli, GI1789453, Length=332, Percent_Identity=28.9156626506024, Blast_Score=99, Evalue=6e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004010
- InterPro:   IPR003122
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR022094 [H]

Pfam domain/function: PF02743 Cache_1; PF00672 HAMP; PF12332 McpA_N; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 57888; Mature: 57757

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVSIGRRLTLNMVWGVFVVLVLVIGNWIGMGHLEQLQATSHEAMARSRSAQETKVIGEK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LYRFVLESVANPDMAGSSSKGWLNRKAEGMAKLKQLAEQTGDDAALGALVASADKAFRGT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
VTLYETKLIPALERGANHEDIMDIDDEISMESDNLSISLLKVAETLEKRAIAASAQYDSF
EEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
SAKLKTFSLALGGIGIVLLVVFSSWLSRSIMRPLRQVIAMMEDVAEGEGDLTKRLEHRSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
DELGKLCTEFNSFVGKVHDTISRTSSVARDVTGSVAEISRTAERLAEGAEEVASQAVMAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TASEEMAATSCEIAGNCQTAAQSSSRARETAARGFAMVENTIAVMNQIARRVRVSAESVQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGARSDQIGEIVMTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTSR
CCCCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
ATREIGEMIKGIQGETRTAVLTMEEGVKEVEAGTREAAKSGEALNEIMQGIEQLNQQMGQ
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
IACAAEQQTSTTMEISGSIQRIKDVAQETAGGAHDSARTSTRLTDLSHDLDRLVSQFRV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SVSIGRRLTLNMVWGVFVVLVLVIGNWIGMGHLEQLQATSHEAMARSRSAQETKVIGEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LYRFVLESVANPDMAGSSSKGWLNRKAEGMAKLKQLAEQTGDDAALGALVASADKAFRGT
HHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCC
VTLYETKLIPALERGANHEDIMDIDDEISMESDNLSISLLKVAETLEKRAIAASAQYDSF
EEEEHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHH
SAKLKTFSLALGGIGIVLLVVFSSWLSRSIMRPLRQVIAMMEDVAEGEGDLTKRLEHRSN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCC
DELGKLCTEFNSFVGKVHDTISRTSSVARDVTGSVAEISRTAERLAEGAEEVASQAVMAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
TASEEMAATSCEIAGNCQTAAQSSSRARETAARGFAMVENTIAVMNQIARRVRVSAESVQ
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLGARSDQIGEIVMTIQDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRALAERTSR
CCCCCCHHHHHHHHHHHHHHCCHHEEHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHH
ATREIGEMIKGIQGETRTAVLTMEEGVKEVEAGTREAAKSGEALNEIMQGIEQLNQQMGQ
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHHH
IACAAEQQTSTTMEISGSIQRIKDVAQETAGGAHDSARTSTRLTDLSHDLDRLVSQFRV
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA