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The map label for this gene is 39995803

Identifier: 39995803

GI number: 39995803

Start: 736709

End: 737908

Strand: Reverse

Name: 39995803

Synonym: GSU0697

Alternate gene names: NA

Gene position: 737908-736709 (Counterclockwise)

Preceding gene: 39995806

Following gene: 39995801

Centisome position: 19.35

GC content: 68.92

Gene sequence:

>1200_bases
ATGGAGAGAATAGCCCTGCCGCGCCGGACACTAGGGGCGCGCCGCAGAGAGGTTCCCGTGACGCCCGACACCCTGCTTCC
CCTCCTCGCCGTTCTCCCGCCGCTGGCCTACGGGCTCCTGGCACTCTTCTGCGCCCGGGCCTGGTTCGGCCGGCAGCGAC
CCGGACCGGGACACACCCCGCCGGTGACCATCCTCAAGCCGGTCAAGGGGATGGACGCAGAGAGCTTCGAGAACTTCGCC
TCCTTCTGCCGCCAGGAGTACGGCGGGCCGTGGCAGATGCTCTTTGCCTGCGCCTCGGCCGACGACCCGGTCATTCCGGT
GATCCGGCGCCTCATGGCCGAGTTTCCGGACCGTGACATCGATCTGGTGGTGGACGGCACCATCCATGGCCCCAACTACA
AGGTCTCCAACCTGATCAACGCCTTCCCAAGGGCCAGGCACGACATCCTCATCGTCTGCGACAGCGACATCCGTGTCACG
TCCGACTATCTGGGGGAGGTGACCGCGCCGTTCGCCGACCCGGCAGTGGGGCTCGTCACCTCTCTCTACCGGAGCCCCGG
CGTACGGGGCGCCGCCACGGCCCTGGAGGCCATGGGGTTCACAGTGGAGATGGTGCCGAACGTCATGGTCGCCCAACGGC
TCGAAGGGCTTTCCTTCGCCCTGGGCGCCTCCATGGCGGTGCGGCGCACGGCACTGGAGTCCATCGGCGGCTTCCCGGCC
CTGACCCACTATCTGGCCGACGACTACCAGCTGGGCAACAAGATCCACCGGGCCGGCTGGCGGCTGGAGCTGTCGGACTG
TTTCGTGGAGAGCGTCATGCACCGGGAGAACCTGACCACGGTCCTCTCCCGCCAGCTCCGCTGGTGCCGCACCATGCGGG
CCTCGCGCCCCGGCGGCTACCTGGGCTCGGGCATCACCCAGCCCGTTCCCCTGGCCTGCCTGGCACTTCTGGTGTCGGGC
TGTTCCGCCGCCGGATGGGGGGCGGTGATCCTCCTCTACCTGACCCGCGCCCTGGTGGCCGTTACCTTCAGCCGCCGGTA
CCTGCGGGACGGCATCTTCCCCCGCTGGCTCTGGCTCCTCCCCCTGCGCGACATCCTCGCCTTCGCCACCTGGGCCCTCT
CCTTCGCCGGCAACCGGGTCCGCTGGCGCGGCAACCTCTTCCGGCTCCTGCCGGGAGGAAAGATCGTGGAAATCGGCTGA

Upstream 100 bases:

>100_bases
GCTCATTGCCGGTGCATCGTAAACGAAAACGGCATACCGTGCAACGCATGCCGTCGGAACCGCTTCCCTGGGGGAAAAAG
GGGTTGCATAATCAGCCCAA

Downstream 100 bases:

>100_bases
GAGTTACACGTACACCATCTTCCGCGTCATTCCCCCGTCCACCACGAAATTGACGCCGGTGACGAATCCCGCCTCGGGCG
AGACCAGCCACGCCGCCAGG

Product: ceramide glucosyltransferase

Products: UDP; D-glucosyl-N-acylsphingosine

Alternate protein names: Glycosyltransferase; Glycosyl Transferase Family Protein; Glucosyltransferase; Cell Wall Biosynthesis Glycosyltransferase-Like Protein; Glycosyl Transferase Group 2 Family; Glycosyl Transferase; Cell Wall Biosynthesis Glycosyltransferase; Glycosyl Transferase Group 2 Family Protein; Acyl-CoA Dehydrogenase-Like; Acyl-CoA Dehydrogenase-Like Protein; UDP-GlucoseCeramide Glycosyltransferase; Glycosyltransferase Family; Glycosyl Transferase Protein; Glycosyl Tranferase Homolog; Syl Transferase Group 2 Family Protein; Putatiave Glycosyltransferase; Family 2 Glycosyl Transferase

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MERIALPRRTLGARRREVPVTPDTLLPLLAVLPPLAYGLLALFCARAWFGRQRPGPGHTPPVTILKPVKGMDAESFENFA
SFCRQEYGGPWQMLFACASADDPVIPVIRRLMAEFPDRDIDLVVDGTIHGPNYKVSNLINAFPRARHDILIVCDSDIRVT
SDYLGEVTAPFADPAVGLVTSLYRSPGVRGAATALEAMGFTVEMVPNVMVAQRLEGLSFALGASMAVRRTALESIGGFPA
LTHYLADDYQLGNKIHRAGWRLELSDCFVESVMHRENLTTVLSRQLRWCRTMRASRPGGYLGSGITQPVPLACLALLVSG
CSAAGWGAVILLYLTRALVAVTFSRRYLRDGIFPRWLWLLPLRDILAFATWALSFAGNRVRWRGNLFRLLPGGKIVEIG

Sequences:

>Translated_399_residues
MERIALPRRTLGARRREVPVTPDTLLPLLAVLPPLAYGLLALFCARAWFGRQRPGPGHTPPVTILKPVKGMDAESFENFA
SFCRQEYGGPWQMLFACASADDPVIPVIRRLMAEFPDRDIDLVVDGTIHGPNYKVSNLINAFPRARHDILIVCDSDIRVT
SDYLGEVTAPFADPAVGLVTSLYRSPGVRGAATALEAMGFTVEMVPNVMVAQRLEGLSFALGASMAVRRTALESIGGFPA
LTHYLADDYQLGNKIHRAGWRLELSDCFVESVMHRENLTTVLSRQLRWCRTMRASRPGGYLGSGITQPVPLACLALLVSG
CSAAGWGAVILLYLTRALVAVTFSRRYLRDGIFPRWLWLLPLRDILAFATWALSFAGNRVRWRGNLFRLLPGGKIVEIG
>Mature_399_residues
MERIALPRRTLGARRREVPVTPDTLLPLLAVLPPLAYGLLALFCARAWFGRQRPGPGHTPPVTILKPVKGMDAESFENFA
SFCRQEYGGPWQMLFACASADDPVIPVIRRLMAEFPDRDIDLVVDGTIHGPNYKVSNLINAFPRARHDILIVCDSDIRVT
SDYLGEVTAPFADPAVGLVTSLYRSPGVRGAATALEAMGFTVEMVPNVMVAQRLEGLSFALGASMAVRRTALESIGGFPA
LTHYLADDYQLGNKIHRAGWRLELSDCFVESVMHRENLTTVLSRQLRWCRTMRASRPGGYLGSGITQPVPLACLALLVSG
CSAAGWGAVILLYLTRALVAVTFSRRYLRDGIFPRWLWLLPLRDILAFATWALSFAGNRVRWRGNLFRLLPGGKIVEIG

Specific function: Unknown

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4507811, Length=350, Percent_Identity=26.2857142857143, Blast_Score=123, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25147526, Length=349, Percent_Identity=24.3553008595989, Blast_Score=109, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI25149574, Length=400, Percent_Identity=24.25, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI25149577, Length=400, Percent_Identity=24.25, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI32564728, Length=344, Percent_Identity=25.5813953488372, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI25149580, Length=295, Percent_Identity=25.7627118644068, Blast_Score=96, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32566973, Length=356, Percent_Identity=24.1573033707865, Blast_Score=89, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24657569, Length=260, Percent_Identity=26.1538461538462, Blast_Score=100, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.4.1.80

Molecular weight: Translated: 44002; Mature: 44002

Theoretical pI: Translated: 9.59; Mature: 9.59

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERIALPRRTLGARRREVPVTPDTLLPLLAVLPPLAYGLLALFCARAWFGRQRPGPGHTP
CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVTILKPVKGMDAESFENFASFCRQEYGGPWQMLFACASADDPVIPVIRRLMAEFPDRDI
CEEHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCE
DLVVDGTIHGPNYKVSNLINAFPRARHDILIVCDSDIRVTSDYLGEVTAPFADPAVGLVT
EEEEECEEECCCCHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHHHCCCCCCHHHHHHH
SLYRSPGVRGAATALEAMGFTVEMVPNVMVAQRLEGLSFALGASMAVRRTALESIGGFPA
HHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
LTHYLADDYQLGNKIHRAGWRLELSDCFVESVMHRENLTTVLSRQLRWCRTMRASRPGGY
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGSGITQPVPLACLALLVSGCSAAGWGAVILLYLTRALVAVTFSRRYLRDGIFPRWLWLL
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
PLRDILAFATWALSFAGNRVRWRGNLFRLLPGGKIVEIG
HHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEEECC
>Mature Secondary Structure
MERIALPRRTLGARRREVPVTPDTLLPLLAVLPPLAYGLLALFCARAWFGRQRPGPGHTP
CCCCCCCHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PVTILKPVKGMDAESFENFASFCRQEYGGPWQMLFACASADDPVIPVIRRLMAEFPDRDI
CEEHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCE
DLVVDGTIHGPNYKVSNLINAFPRARHDILIVCDSDIRVTSDYLGEVTAPFADPAVGLVT
EEEEECEEECCCCHHHHHHHHHCCCCCCEEEEECCCCEECHHHHHHHCCCCCCHHHHHHH
SLYRSPGVRGAATALEAMGFTVEMVPNVMVAQRLEGLSFALGASMAVRRTALESIGGFPA
HHHHCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHH
LTHYLADDYQLGNKIHRAGWRLELSDCFVESVMHRENLTTVLSRQLRWCRTMRASRPGGY
HHHHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LGSGITQPVPLACLALLVSGCSAAGWGAVILLYLTRALVAVTFSRRYLRDGIFPRWLWLL
CCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
PLRDILAFATWALSFAGNRVRWRGNLFRLLPGGKIVEIG
HHHHHHHHHHHHHHHCCCEEEEECCEEEECCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: UDP-glucose; N-acylsphingosine

Specific reaction: UDP-glucose + N-acylsphingosine = UDP + D-glucosyl-N-acylsphingosine

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA