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The map label for this gene is ffH [H]

Identifier: 39995748

GI number: 39995748

Start: 676434

End: 677792

Strand: Direct

Name: ffH [H]

Synonym: GSU0642

Alternate gene names: 39995748

Gene position: 676434-677792 (Clockwise)

Preceding gene: 39995747

Following gene: 39995749

Centisome position: 17.73

GC content: 59.75

Gene sequence:

>1359_bases
ATGCTCGAAAATCTTTCCGACAAGCTTGACGTCCTCTTTAAAAAACTCCGCGGTCAGGGAGTGATGAGCGAGGAGAATAT
CAAGGAGGCGCTGCGCGAGGTGCGGCTCGTTCTTCTTGAAGCCGACGTTAACTTCAAGGTCGTCAAGGACTTTGTCGAAA
GAGTTCGTGTCCGTGCCGTCGGCACCCAGGTGCTCCAGAGTCTCACGCCGGGGCAGCAGGTCATCAAGATTGTTCAGGAA
GAGCTTGTGGCCCTCATGGGCGGGGGCGAGGACAATAGTCTCGATCTGGCTGCAAAGCCGCCGGTCCCCATCATGATGGT
AGGCCTTCAGGGGGCCGGCAAGACCACCTCCTGCGGCAAGCTGGCCCGGCTGCTCAAGGGGCAGCGGCGTCGACCGCTCC
TGGTGCCTGCCGACGTCTACCGGCCTGCTGCGATTGAGCAGCTGAAGACCCTCGGGCGGCAGCTGTCCGTGGAAGTGTTC
GATTCCCGGGCAGATCAGGATCCGGTCGACATCTGCCGCGAAGCGCTCCGTTACGCAACTCTCAACGGCTTCGACGTGGT
CATTCTTGACACCGCCGGCCGCCACCAGATCGACGAGTATCTCATGAATGAGCTCGTCAGGATCAAGGAGGCGGCGGAGC
CGCGGGAAATCCTCTTCGTCGCCGACGCCATGACCGGCCAGGAAGCGGTCAATGTGGCCAGCGGCTTCAATGACCGGCTC
GATATTACCGGCGTGGTCCTTACCAAGCTCGACGGTGATGCGAAGGGGGGGGCAGCGCTCTCAATCCGGGCGGTGACCGG
CAAGCCGGTGAAACTTGTGGGGGTCGGCGAAAAGCTCGACGCCCTGGAAGTTTTTCATGCGGATCGTCTGGTGTCGCGCA
TCCTCGGAATGGGTGATATTCTTACCCTTGTGGAGAAGGCCCAGGCGACCTTCGATTCTCAGGAGGCCGAACGGCTTCAG
CAGAAGCTCAAGAAAAGCCAGTTCGATCTGGAGGATTTCCGCAACCAGCTGCAACAGATCAAGAAGATGGGCTCCATTGA
GTCGATTCTCGGCATGATTCCGGGGGTCGGTAAGGCCATGAAGCAACTGCAGGGCGCTCAACCTTCCGAGCGAGAGCTCA
AGCGGATCGAGGCGATCATTGGCTCCATGACCCCTGCCGAGCGTGCGAACCACGCGATCATCAATGGCAGCAGGCGGCTG
CGCATCGCCAAGGGGAGCGGCACCACCGTTCAGGAGGTGAACCAGCTTCTCAAGCGTTTCACCGAGGCGCAGAAAATGAT
GAAGCAGCTTCAGAAGCTCGGACCAAAGGGCCTGATGCGCGGTATGAAAGGGATGGGCAAGGGGATGTTTCCCTTTTGA

Upstream 100 bases:

>100_bases
AGACAGGGGGGCTATAGTTAACCTCTTTCTCCATGGTAACGTGCGCGCAGTAGCCGTAGTTTTTGGTGTGGCCGCATAAT
ATATTGAATTAATTGAGATA

Downstream 100 bases:

>100_bases
TGCATTCATACGAAGTCCGAAGCAGGATATAACGACATTCACCTATGCGGCCTCCGGGCCGTGACACCACCAGGAGGAAG
AGATGGCCACAAGATTCGTC

Product: signal recognition particle protein

Products: NA

Alternate protein names: Fifty-four homolog [H]

Number of amino acids: Translated: 452; Mature: 452

Protein sequence:

>452_residues
MLENLSDKLDVLFKKLRGQGVMSEENIKEALREVRLVLLEADVNFKVVKDFVERVRVRAVGTQVLQSLTPGQQVIKIVQE
ELVALMGGGEDNSLDLAAKPPVPIMMVGLQGAGKTTSCGKLARLLKGQRRRPLLVPADVYRPAAIEQLKTLGRQLSVEVF
DSRADQDPVDICREALRYATLNGFDVVILDTAGRHQIDEYLMNELVRIKEAAEPREILFVADAMTGQEAVNVASGFNDRL
DITGVVLTKLDGDAKGGAALSIRAVTGKPVKLVGVGEKLDALEVFHADRLVSRILGMGDILTLVEKAQATFDSQEAERLQ
QKLKKSQFDLEDFRNQLQQIKKMGSIESILGMIPGVGKAMKQLQGAQPSERELKRIEAIIGSMTPAERANHAIINGSRRL
RIAKGSGTTVQEVNQLLKRFTEAQKMMKQLQKLGPKGLMRGMKGMGKGMFPF

Sequences:

>Translated_452_residues
MLENLSDKLDVLFKKLRGQGVMSEENIKEALREVRLVLLEADVNFKVVKDFVERVRVRAVGTQVLQSLTPGQQVIKIVQE
ELVALMGGGEDNSLDLAAKPPVPIMMVGLQGAGKTTSCGKLARLLKGQRRRPLLVPADVYRPAAIEQLKTLGRQLSVEVF
DSRADQDPVDICREALRYATLNGFDVVILDTAGRHQIDEYLMNELVRIKEAAEPREILFVADAMTGQEAVNVASGFNDRL
DITGVVLTKLDGDAKGGAALSIRAVTGKPVKLVGVGEKLDALEVFHADRLVSRILGMGDILTLVEKAQATFDSQEAERLQ
QKLKKSQFDLEDFRNQLQQIKKMGSIESILGMIPGVGKAMKQLQGAQPSERELKRIEAIIGSMTPAERANHAIINGSRRL
RIAKGSGTTVQEVNQLLKRFTEAQKMMKQLQKLGPKGLMRGMKGMGKGMFPF
>Mature_452_residues
MLENLSDKLDVLFKKLRGQGVMSEENIKEALREVRLVLLEADVNFKVVKDFVERVRVRAVGTQVLQSLTPGQQVIKIVQE
ELVALMGGGEDNSLDLAAKPPVPIMMVGLQGAGKTTSCGKLARLLKGQRRRPLLVPADVYRPAAIEQLKTLGRQLSVEVF
DSRADQDPVDICREALRYATLNGFDVVILDTAGRHQIDEYLMNELVRIKEAAEPREILFVADAMTGQEAVNVASGFNDRL
DITGVVLTKLDGDAKGGAALSIRAVTGKPVKLVGVGEKLDALEVFHADRLVSRILGMGDILTLVEKAQATFDSQEAERLQ
QKLKKSQFDLEDFRNQLQQIKKMGSIESILGMIPGVGKAMKQLQGAQPSERELKRIEAIIGSMTPAERANHAIINGSRRL
RIAKGSGTTVQEVNQLLKRFTEAQKMMKQLQKLGPKGLMRGMKGMGKGMFPF

Specific function: Necessary for efficient export of extracytoplasmic proteins. Binds to the signal sequence when it emerges from the ribosomes [H]

COG id: COG0541

COG function: function code U; Signal recognition particle GTPase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding SRP family [H]

Homologues:

Organism=Homo sapiens, GI4507215, Length=450, Percent_Identity=35.7777777777778, Blast_Score=260, Evalue=2e-69,
Organism=Homo sapiens, GI226371618, Length=387, Percent_Identity=36.9509043927649, Blast_Score=233, Evalue=3e-61,
Organism=Homo sapiens, GI89061728, Length=165, Percent_Identity=39.3939393939394, Blast_Score=124, Evalue=3e-28,
Organism=Homo sapiens, GI23308697, Length=314, Percent_Identity=29.9363057324841, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI295424842, Length=314, Percent_Identity=29.9363057324841, Blast_Score=115, Evalue=6e-26,
Organism=Escherichia coli, GI1788963, Length=453, Percent_Identity=52.7593818984547, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI1789874, Length=215, Percent_Identity=37.6744186046512, Blast_Score=150, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17539958, Length=456, Percent_Identity=33.5526315789474, Blast_Score=242, Evalue=3e-64,
Organism=Caenorhabditis elegans, GI193206261, Length=311, Percent_Identity=31.1897106109325, Blast_Score=117, Evalue=9e-27,
Organism=Saccharomyces cerevisiae, GI6325345, Length=430, Percent_Identity=33.2558139534884, Blast_Score=233, Evalue=5e-62,
Organism=Saccharomyces cerevisiae, GI6320498, Length=224, Percent_Identity=27.6785714285714, Blast_Score=92, Evalue=2e-19,
Organism=Drosophila melanogaster, GI17647949, Length=456, Percent_Identity=34.4298245614035, Blast_Score=239, Evalue=3e-63,
Organism=Drosophila melanogaster, GI24641198, Length=316, Percent_Identity=28.4810126582279, Blast_Score=119, Evalue=3e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR000897
- InterPro:   IPR013822
- InterPro:   IPR004780
- InterPro:   IPR004125 [H]

Pfam domain/function: PF00448 SRP54; PF02881 SRP54_N; PF02978 SRP_SPB [H]

EC number: NA

Molecular weight: Translated: 49701; Mature: 49701

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: PS00300 SRP54

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLENLSDKLDVLFKKLRGQGVMSEENIKEALREVRLVLLEADVNFKVVKDFVERVRVRAV
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GTQVLQSLTPGQQVIKIVQEELVALMGGGEDNSLDLAAKPPVPIMMVGLQGAGKTTSCGK
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCCCHHHH
LARLLKGQRRRPLLVPADVYRPAAIEQLKTLGRQLSVEVFDSRADQDPVDICREALRYAT
HHHHHCCCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
LNGFDVVILDTAGRHQIDEYLMNELVRIKEAAEPREILFVADAMTGQEAVNVASGFNDRL
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCCCC
DITGVVLTKLDGDAKGGAALSIRAVTGKPVKLVGVGEKLDALEVFHADRLVSRILGMGDI
EEEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHH
LTLVEKAQATFDSQEAERLQQKLKKSQFDLEDFRNQLQQIKKMGSIESILGMIPGVGKAM
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHH
KQLQGAQPSERELKRIEAIIGSMTPAERANHAIINGSRRLRIAKGSGTTVQEVNQLLKRF
HHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHHH
TEAQKMMKQLQKLGPKGLMRGMKGMGKGMFPF
HHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLENLSDKLDVLFKKLRGQGVMSEENIKEALREVRLVLLEADVNFKVVKDFVERVRVRAV
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHH
GTQVLQSLTPGQQVIKIVQEELVALMGGGEDNSLDLAAKPPVPIMMVGLQGAGKTTSCGK
HHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCEEEEEECCCCCCCHHHH
LARLLKGQRRRPLLVPADVYRPAAIEQLKTLGRQLSVEVFDSRADQDPVDICREALRYAT
HHHHHCCCCCCCEECCHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHC
LNGFDVVILDTAGRHQIDEYLMNELVRIKEAAEPREILFVADAMTGQEAVNVASGFNDRL
CCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCHHHHHHHCCCCCCC
DITGVVLTKLDGDAKGGAALSIRAVTGKPVKLVGVGEKLDALEVFHADRLVSRILGMGDI
EEEEEEEEEECCCCCCCCEEEEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCHHH
LTLVEKAQATFDSQEAERLQQKLKKSQFDLEDFRNQLQQIKKMGSIESILGMIPGVGKAM
HHHHHHHHHHCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHH
KQLQGAQPSERELKRIEAIIGSMTPAERANHAIINGSRRLRIAKGSGTTVQEVNQLLKRF
HHHCCCCCCHHHHHHHHHHHHCCCCHHHCCCEEECCCCEEEEECCCCCCHHHHHHHHHHH
TEAQKMMKQLQKLGPKGLMRGMKGMGKGMFPF
HHHHHHHHHHHHHCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8335643; 9384377; 7511896 [H]