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The map label for this gene is atoS [H]

Identifier: 39995706

GI number: 39995706

Start: 630362

End: 631912

Strand: Reverse

Name: atoS [H]

Synonym: GSU0599

Alternate gene names: 39995706

Gene position: 631912-630362 (Counterclockwise)

Preceding gene: 39995710

Following gene: 39995704

Centisome position: 16.57

GC content: 57.25

Gene sequence:

>1551_bases
ATGGGGCTCTTTGCCTATATCAACGTGGAGCAGCTGGAGAAACTCCTCTTTGAAGAGGCGGTTTCCGACGCCGACAAGCT
CAGCGAAACGATCATCCGCACCACCCACTACCACATGCTCGAAGACAACCGCGAGCGCGCCTATCAGATCATCAACGAGG
TGGGGAGTCAGAAGGGAATCACCCAGCGGATCAGAATGATCAACAAGTTCGGCCAGGTGACCCATTCGACGGACCAGAGG
GAAATCGGCTACTTCCTGGATAAAAAGGCCGAGGCTTGCAACATGTGCCATTCGGGCCCCTCGCCCCTGGTCCATGCCAC
CACCATGAACCGCAGCCGCCTCTTCACCGACAGGGAAGGAAAACAGGTTCTCGGCCTTGCAAAGGCCATCTACAACGACG
AGCGCTGCTTTACCGCCCCCTGCCACTATCACCCGAAGGAGGCAAAAGTCCTGGGAGTCCTCGACGTTATCGTCTCCCTC
GACCCCATGCATCAGAAGGTCTACGCCTACCGCAACGAGATCATCGTGCTGACGGTGCTGCAGATCACGCTCATCGCCCT
CTGCCTGACCTTTTTCACCCAGCGCTTCGTCAACAGACCGGTACGGCAGCTAGTCAGGCTTACCCAGCAGGTTGGCGAAG
GAGATCTGGATACTCGGGTGACGCTGTCGTCCCATGACGAGCTGGGAGAATTGGCATCGGCCTTCAACTCCATGACCGTC
AACCTCAAGAAGGTTCATGGCGAGCTTGAGGATTGGGGCAAAAACCTGGAGGTAAAAGTTGAGGAGCGGACCCAGGAGCT
CAAGAACATTCAGGCCCAGCTCGTCCATTCCGAAAAACTTGCCTCTCTGGGCGAACTGGTGGCCGGCATTGCCCACGAAA
TCAACAACCCCCTGACCGGCATCCTGGTCTTCGCGTCGCTCATGGCCAGTGACAAAAAACTTGATCCGTCGCTCAAGGCC
GACCTGGACCTGATCGTCAAAGAGACCCAGCGCTGTGCCAAGATCGTCAAGGGGCTCCTCGATTTCTCCAGGGAGTCGAT
CCCGCAGAAAAAGCCCTCTTCCATCAATGCCATCATGGATGCCACCCTGACCTTGGTGGTCCACCAGTCATGCTTCCACG
ACATCACCGTCGTTAAAGAGTACAACCCGGACATACCGGAAATGCTCCTTGATCCCCACCAGATTGAACAGGTATTCATC
AACCTCCTCCTGAACGCCTGCCACGCCATTGCCGGCTCGGGAGAAGTACACATCAGGACGGGGTTTGATCACGTGAATGA
CGAGGTCAGCGTTGCAATTACCGATACAGGCTGTGGTATCCCCGATGAAATAATCGGCAAGATATTCGACCCCTTCTTTA
CCACCAAGGAAACCAAAGGGACGGGGCTGGGCCTCTCGGTTTCTTACGGGATCATCGAGGGGCACGGCGGCAGGATCGAT
GTGCAGAGTACCGTGGGGGCGGGTACCACGTTCACTGTGCGCCTCCCCCTCCTCCACGAGGCGCCCCTCGAAGCTGCAGC
AGCAGCCGGCCAGCGACAGCAAAGCGCCTGA

Upstream 100 bases:

>100_bases
ACTTCACAGCAACTCCGTCAGATAATCGGGAACCGCTGCCGTGCGCCTGAGCCTTCTCGCCAAATTCACGATTGCCACCA
GCTTCGTACTCCTCGTCACC

Downstream 100 bases:

>100_bases
TCCGACTGCGGTACGGACATCAAGACAGCCGTAAATACAAAAAGGGGCACACGCGCGTGTGCCCCTTTTTGTATTTGAGC
CGGTACGCCGAGATGTTCAG

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 516; Mature: 515

Protein sequence:

>516_residues
MGLFAYINVEQLEKLLFEEAVSDADKLSETIIRTTHYHMLEDNRERAYQIINEVGSQKGITQRIRMINKFGQVTHSTDQR
EIGYFLDKKAEACNMCHSGPSPLVHATTMNRSRLFTDREGKQVLGLAKAIYNDERCFTAPCHYHPKEAKVLGVLDVIVSL
DPMHQKVYAYRNEIIVLTVLQITLIALCLTFFTQRFVNRPVRQLVRLTQQVGEGDLDTRVTLSSHDELGELASAFNSMTV
NLKKVHGELEDWGKNLEVKVEERTQELKNIQAQLVHSEKLASLGELVAGIAHEINNPLTGILVFASLMASDKKLDPSLKA
DLDLIVKETQRCAKIVKGLLDFSRESIPQKKPSSINAIMDATLTLVVHQSCFHDITVVKEYNPDIPEMLLDPHQIEQVFI
NLLLNACHAIAGSGEVHIRTGFDHVNDEVSVAITDTGCGIPDEIIGKIFDPFFTTKETKGTGLGLSVSYGIIEGHGGRID
VQSTVGAGTTFTVRLPLLHEAPLEAAAAAGQRQQSA

Sequences:

>Translated_516_residues
MGLFAYINVEQLEKLLFEEAVSDADKLSETIIRTTHYHMLEDNRERAYQIINEVGSQKGITQRIRMINKFGQVTHSTDQR
EIGYFLDKKAEACNMCHSGPSPLVHATTMNRSRLFTDREGKQVLGLAKAIYNDERCFTAPCHYHPKEAKVLGVLDVIVSL
DPMHQKVYAYRNEIIVLTVLQITLIALCLTFFTQRFVNRPVRQLVRLTQQVGEGDLDTRVTLSSHDELGELASAFNSMTV
NLKKVHGELEDWGKNLEVKVEERTQELKNIQAQLVHSEKLASLGELVAGIAHEINNPLTGILVFASLMASDKKLDPSLKA
DLDLIVKETQRCAKIVKGLLDFSRESIPQKKPSSINAIMDATLTLVVHQSCFHDITVVKEYNPDIPEMLLDPHQIEQVFI
NLLLNACHAIAGSGEVHIRTGFDHVNDEVSVAITDTGCGIPDEIIGKIFDPFFTTKETKGTGLGLSVSYGIIEGHGGRID
VQSTVGAGTTFTVRLPLLHEAPLEAAAAAGQRQQSA
>Mature_515_residues
GLFAYINVEQLEKLLFEEAVSDADKLSETIIRTTHYHMLEDNRERAYQIINEVGSQKGITQRIRMINKFGQVTHSTDQRE
IGYFLDKKAEACNMCHSGPSPLVHATTMNRSRLFTDREGKQVLGLAKAIYNDERCFTAPCHYHPKEAKVLGVLDVIVSLD
PMHQKVYAYRNEIIVLTVLQITLIALCLTFFTQRFVNRPVRQLVRLTQQVGEGDLDTRVTLSSHDELGELASAFNSMTVN
LKKVHGELEDWGKNLEVKVEERTQELKNIQAQLVHSEKLASLGELVAGIAHEINNPLTGILVFASLMASDKKLDPSLKAD
LDLIVKETQRCAKIVKGLLDFSRESIPQKKPSSINAIMDATLTLVVHQSCFHDITVVKEYNPDIPEMLLDPHQIEQVFIN
LLLNACHAIAGSGEVHIRTGFDHVNDEVSVAITDTGCGIPDEIIGKIFDPFFTTKETKGTGLGLSVSYGIIEGHGGRIDV
QSTVGAGTTFTVRLPLLHEAPLEAAAAAGQRQQSA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=230, Percent_Identity=38.2608695652174, Blast_Score=161, Evalue=9e-41,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=34.8936170212766, Blast_Score=137, Evalue=2e-33,
Organism=Escherichia coli, GI87081816, Length=353, Percent_Identity=28.328611898017, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789149, Length=358, Percent_Identity=25.9776536312849, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790300, Length=237, Percent_Identity=33.3333333333333, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI145693157, Length=259, Percent_Identity=32.046332046332, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788393, Length=307, Percent_Identity=25.7328990228013, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1789808, Length=322, Percent_Identity=22.9813664596273, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI87082128, Length=360, Percent_Identity=23.6111111111111, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI48994928, Length=225, Percent_Identity=27.1111111111111, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1786600, Length=258, Percent_Identity=25.5813953488372, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1790346, Length=229, Percent_Identity=24.8908296943231, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786783, Length=341, Percent_Identity=23.1671554252199, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=25.5411255411255, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 57226; Mature: 57095

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLFAYINVEQLEKLLFEEAVSDADKLSETIIRTTHYHMLEDNRERAYQIINEVGSQKGI
CCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCH
TQRIRMINKFGQVTHSTDQREIGYFLDKKAEACNMCHSGPSPLVHATTMNRSRLFTDREG
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHCCCCCCEEEEEECCCHHCCCCCCC
KQVLGLAKAIYNDERCFTAPCHYHPKEAKVLGVLDVIVSLDPMHQKVYAYRNEIIVLTVL
HHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
QITLIALCLTFFTQRFVNRPVRQLVRLTQQVGEGDLDTRVTLSSHDELGELASAFNSMTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEE
NLKKVHGELEDWGKNLEVKVEERTQELKNIQAQLVHSEKLASLGELVAGIAHEINNPLTG
EHHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ILVFASLMASDKKLDPSLKADLDLIVKETQRCAKIVKGLLDFSRESIPQKKPSSINAIMD
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ATLTLVVHQSCFHDITVVKEYNPDIPEMLLDPHQIEQVFINLLLNACHAIAGSGEVHIRT
HHHHHHHHHHHHHCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GFDHVNDEVSVAITDTGCGIPDEIIGKIFDPFFTTKETKGTGLGLSVSYGIIEGHGGRID
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEE
VQSTVGAGTTFTVRLPLLHEAPLEAAAAAGQRQQSA
EEECCCCCCEEEEEECCHHHCCHHHHHHCCCCCCCC
>Mature Secondary Structure 
GLFAYINVEQLEKLLFEEAVSDADKLSETIIRTTHYHMLEDNRERAYQIINEVGSQKGI
CEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCH
TQRIRMINKFGQVTHSTDQREIGYFLDKKAEACNMCHSGPSPLVHATTMNRSRLFTDREG
HHHHHHHHHHHHHCCCCCCHHHHHHHHCCHHHHHHHCCCCCCEEEEEECCCHHCCCCCCC
KQVLGLAKAIYNDERCFTAPCHYHPKEAKVLGVLDVIVSLDPMHQKVYAYRNEIIVLTVL
HHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHH
QITLIALCLTFFTQRFVNRPVRQLVRLTQQVGEGDLDTRVTLSSHDELGELASAFNSMTV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHEE
NLKKVHGELEDWGKNLEVKVEERTQELKNIQAQLVHSEKLASLGELVAGIAHEINNPLTG
EHHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHH
ILVFASLMASDKKLDPSLKADLDLIVKETQRCAKIVKGLLDFSRESIPQKKPSSINAIMD
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHH
ATLTLVVHQSCFHDITVVKEYNPDIPEMLLDPHQIEQVFINLLLNACHAIAGSGEVHIRT
HHHHHHHHHHHHHCEEEEECCCCCCHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEE
GFDHVNDEVSVAITDTGCGIPDEIIGKIFDPFFTTKETKGTGLGLSVSYGIIEGHGGRID
CCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEEEEECCCCEEE
VQSTVGAGTTFTVRLPLLHEAPLEAAAAAGQRQQSA
EEECCCCCCEEEEEECCHHHCCHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]