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The map label for this gene is cat1 [H]

Identifier: 39995598

GI number: 39995598

Start: 521516

End: 523111

Strand: Direct

Name: cat1 [H]

Synonym: GSU0490

Alternate gene names: 39995598

Gene position: 521516-523111 (Clockwise)

Preceding gene: 39995597

Following gene: 39995601

Centisome position: 13.67

GC content: 60.09

Gene sequence:

>1596_bases
ATGTCAGAGTACGGCACACTGCAGGACCGCGTACGTTGCAAGTCACTGCTCAACAAGGTTATGTCGGCCGAGGAGACTAT
CCAGTTCTTCAAGCCGGGCATGAACCTTGGCTGGTCCGGCTTCACCCCGGCAGGTTATCCTAAGGCAGTGCCCATCGCAC
TGGCAGATCACGTTGAGAAGAACAGCCTGCAGGGCAAGATGAAGTTCAACCTCTTCATCGGCGCCTCCGTCGGGGCCGAA
ACCGAAGACCGCTGGGCCACTCTCGACATGATCGACCGTCGCTGGCCGTATCAGACCGGTAAGAACATCGCCGCCGGCAT
CAACGAGGGCCGCATCCGGATGGGTGACAAGCACCTCTCCCTCTTTGCCCAGGATCTGGGCTACGGCTTCTACACCAAGG
ACAGCGAAACCGGCAAGCTTGACCTCGCCATCATCGAGGTTTCCGCCATCACCGAAGACGGCGGACTGGTCCCCACCACC
TCTTGCGGCGTTATTCCCGAGATCCTCATGATCTGCGACAAGATCATCGTGGAAGTGAACACCGGTCAGCCCTCCTTCGA
GGGGATGCACGACATCGTCGTCTGCAACCACCCCCCGAAGCGCCAGATTCTGGGCATCACCCATGCCGGTGAGCGGATCG
GTACAACCTACGTACCGTGCGACCCGAGCAAGATCATCGCCGTGGTTGAGTCCAAGTACCGTGACAAGGGGCGTGCCTTC
TCCGAGCAGGACGACACCTCCGAGGCCATTGCCAACAACATCATCGACTTCTTCAGCCATGAAGTAAAGATGGGTCGTCT
GCCCAAGAACCTGCTTCCGCTCCAGTCAGGCGTCGGTTCCATCGCCAACGCTGTAATCGGCGGCCTGGCCAAGGGTCCTT
TCTCCAACCTGACCGTTTACACCGAAGTTCTCCAGGACACCATGCTCGACCTGTTCGATTCGGGCAAGCTGGATGCCGCT
TCCTCCTGCTCCCTCTCTCTCTCCGAGACCCCGGGCTTCCCCCGTTTCTTCGAGAACTGGGAGAAGTACTTCGACAAGAT
CACCCTGCGTCCGCTCTCCATCTCCAACGCACCGGAGCCGATCCGCCGTCTCGGGTGCATCGCCATGAACACCCCGGTCG
AGATCGACATCTATGCCCACGCCAACTCCACGCTGGTCGGCGGCACACGGATGATCAACGGCCTCGGCGGTTCCGGCGAC
TTCCTTCGCAACGGCTTCTTGAAGATCATGCACACTCCGTCGAGCCGTCCATCCAAGACCGACCCGACCGGTATCTCCTG
CGTGGTGCCGCACTGCTCCCACATCGACCACACCGAGCACGATCTGGACTGCGTGGTCACCGAGCAGGGTCTGGCCGACC
TCCGTGGTCTGGCACCGAAGGATCGCGCAAAGCGGATTATCGAGAAGTGCGCCCACCCGGACTACAAGCCGATTCTCAGC
GAGTACTTGGCAATCGCCAGTGCCGATTGCCTCAAGCGCAAGGTGGGCCACGAGCCGCAACTGTGGGACCGCGCCTTCAA
GATGCACCTCAACCTGGAGCGCAACGGCACCATGAAGATCAAGAACTGGGACGTGAAGGTCGATCTCTGCGAGTAA

Upstream 100 bases:

>100_bases
AGCGTTCAGTAGCGTTGATGTTATGCAAATGAGGTAACGGCGAAGTTTCGTTAAGCCGCAGAACGTCGCTGTAAACAACA
AAACAGAACGGAGGTAAGAG

Downstream 100 bases:

>100_bases
GGTCGACAGTCAGTATCAGGCATGAAAAAAGCCCCGCCGAACTTCGGCGGGGCTTTTTCGTATCTCTCAACGGGGGAAAA
CGGGAACGGTATCCCCTGGC

Product: acetyl-CoA hydrolase/transferase

Products: propionate; succinyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MSEYGTLQDRVRCKSLLNKVMSAEETIQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEKNSLQGKMKFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSLFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTT
SCGVIPEILMICDKIIVEVNTGQPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKYRDKGRAF
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSETPGFPRFFENWEKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKIMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGLAPKDRAKRIIEKCAHPDYKPILS
EYLAIASADCLKRKVGHEPQLWDRAFKMHLNLERNGTMKIKNWDVKVDLCE

Sequences:

>Translated_531_residues
MSEYGTLQDRVRCKSLLNKVMSAEETIQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEKNSLQGKMKFNLFIGASVGAE
TEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSLFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTT
SCGVIPEILMICDKIIVEVNTGQPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKYRDKGRAF
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVYTEVLQDTMLDLFDSGKLDAA
SSCSLSLSETPGFPRFFENWEKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGD
FLRNGFLKIMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGLAPKDRAKRIIEKCAHPDYKPILS
EYLAIASADCLKRKVGHEPQLWDRAFKMHLNLERNGTMKIKNWDVKVDLCE
>Mature_530_residues
SEYGTLQDRVRCKSLLNKVMSAEETIQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEKNSLQGKMKFNLFIGASVGAET
EDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLSLFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTTS
CGVIPEILMICDKIIVEVNTGQPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKYRDKGRAFS
EQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVYTEVLQDTMLDLFDSGKLDAAS
SCSLSLSETPGFPRFFENWEKYFDKITLRPLSISNAPEPIRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDF
LRNGFLKIMHTPSSRPSKTDPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGLAPKDRAKRIIEKCAHPDYKPILSE
YLAIASADCLKRKVGHEPQLWDRAFKMHLNLERNGTMKIKNWDVKVDLCE

Specific function: Forms succinyl-CoA from succinate and acetyl-CoA [H]

COG id: COG0427

COG function: function code C; Acetyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetyl-CoA hydrolase/transferase family [H]

Homologues:

Organism=Escherichia coli, GI1789287, Length=502, Percent_Identity=41.0358565737052, Blast_Score=382, Evalue=1e-107,
Organism=Saccharomyces cerevisiae, GI6319456, Length=525, Percent_Identity=57.1428571428571, Blast_Score=606, Evalue=1e-174,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003702
- InterPro:   IPR006472
- InterPro:   IPR017821 [H]

Pfam domain/function: PF02550 AcetylCoA_hydro; PF04223 CitF [H]

EC number: NA

Molecular weight: Translated: 58504; Mature: 58372

Theoretical pI: Translated: 6.56; Mature: 6.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEYGTLQDRVRCKSLLNKVMSAEETIQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEK
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NSLQGKMKFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLS
CCCCCEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHH
LFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTTSCGVIPEILMICDKIIVEVN
HHHHHHCCCEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEC
TGQPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKYRDKGRAF
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCC
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSETPGFPRFFENWEKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHCCCEEEEECCCCCCCCC
DPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGLAPKDRAKRIIEKCAHPDYKPILS
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EYLAIASADCLKRKVGHEPQLWDRAFKMHLNLERNGTMKIKNWDVKVDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEEECEEEEEECC
>Mature Secondary Structure 
SEYGTLQDRVRCKSLLNKVMSAEETIQFFKPGMNLGWSGFTPAGYPKAVPIALADHVEK
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHH
NSLQGKMKFNLFIGASVGAETEDRWATLDMIDRRWPYQTGKNIAAGINEGRIRMGDKHLS
CCCCCEEEEEEEEECCCCCCCCCCEEHHHHHHCCCCCCCCCCCCCCCCCCCEEECHHHHH
LFAQDLGYGFYTKDSETGKLDLAIIEVSAITEDGGLVPTTSCGVIPEILMICDKIIVEVN
HHHHHHCCCEEECCCCCCEEEEEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHEEEEC
TGQPSFEGMHDIVVCNHPPKRQILGITHAGERIGTTYVPCDPSKIIAVVESKYRDKGRAF
CCCCCCCCCEEEEEECCCCCCCEEEEEECCCCCCCEECCCCHHHHHHHHHHHHHHCCCCC
SEQDDTSEAIANNIIDFFSHEVKMGRLPKNLLPLQSGVGSIANAVIGGLAKGPFSNLTVY
CCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
TEVLQDTMLDLFDSGKLDAASSCSLSLSETPGFPRFFENWEKYFDKITLRPLSISNAPEP
HHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHEEEEEEECCCCCHH
IRRLGCIAMNTPVEIDIYAHANSTLVGGTRMINGLGGSGDFLRNGFLKIMHTPSSRPSKT
HHHHCCEEECCCEEEEEEEECCCEEECCHHHCCCCCCCCHHHHCCCEEEEECCCCCCCCC
DPTGISCVVPHCSHIDHTEHDLDCVVTEQGLADLRGLAPKDRAKRIIEKCAHPDYKPILS
CCCCCEEEECCCCCCCCCCCCCEEEEECCCHHHHHCCCCHHHHHHHHHHHCCCCHHHHHH
EYLAIASADCLKRKVGHEPQLWDRAFKMHLNLERNGTMKIKNWDVKVDLCE
HHHHHHHHHHHHHHHCCCCHHHHHHHHEEEEECCCCEEEEEECEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: propionyl-CoA; succinate [C]

Specific reaction: propionyl-CoA + succinate = propionate + succinyl-CoA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8550525 [H]