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The map label for this gene is hypD [H]

Identifier: 39995417

GI number: 39995417

Start: 340904

End: 341995

Strand: Direct

Name: hypD [H]

Synonym: GSU0308

Alternate gene names: 39995417

Gene position: 340904-341995 (Clockwise)

Preceding gene: 39995416

Following gene: 39995418

Centisome position: 8.94

GC content: 65.84

Gene sequence:

>1092_bases
ATGAATTACCAGGACGAGTTTCGCGATCGGGCCCTGGTGCAGGGGTATGCGCAGCGCATCGCCCGGTTGGTGGAGGGACG
CACGGACGTCATGACCTTCATGGAGGTCTGCGGCACCCACACCATGTCGATCTACCAGTACGGCCTCCGCAGCCTCCTGC
CGCCCCAGGTGCGGCTCATCTCCGGCCCGGGCTGCCCCGTCTGCGTGACCCCCAACGAATACCTGGACCGGGCCGTGGCC
CTCTGCCGTCTCCCCGGTGTCATCGTCGCCACCTTCGGCGACATGGTCCGGGTGCCGGGCTCCTCCTCGTCGCTCCAAGA
GGAGCGGGCCATGGGGGCAGACGTGCGCATCGTCTATTCCCCGCTCGACGCCGTTGCCCTGGCGGCGGCGAATCCGGACC
GGAAAGTGGTTTTTCTCGGGGTTGGTTTCGAAACCACGGCTCCGGCCATCGGCGGAAGCATTCTCGCGGCCCGGAAGCAG
GGGCTTGCCAACTACTTCGTCCTGGCTGCCCACAAGACCATGCCGATCCCCATGCGTGTTCTGGCCAATGACCCCGAGCT
CGGCATCGACGGCTACCTGTGCCCGGCCCACGTCAGCACTATAATCGGTGCCGACGCGTACCGCTTCCTTCCCGAGGAGT
TCGGCATCCCCTGTGTGGTAACGGGCTTCGAGCCGGTCGACGTCATGCAGGGGGTGGAGATGCTTGTCCGCCAGGTCGTG
GAGGGAAAGCCCCGGGTCGAGATCCAGTACAGCCGTGTGGCCACCTGGGAGGGGAACCGCAAGGCCCTGGACGTACTCGC
CCAGGTATTCACTCCCTTTGACGCACCCTGGCGGGGGATCGGCATCATTCCGGGAAGTGGCCTCCGGATCGCCGATGCCT
ACGCCGCCTTCGACGCCGAGCGGGAGATCGCGGTGGAGGTCGAAGAGACCAAAGAGCACCAGGGGTGTCTCTGCGGGGAG
ATCCTCAAGGGGAAAGTGACACCCTTCGACTGTCCCCTGTTTGCCAACGCCTGCACCCCCGAGTCGCCCGTGGGCGCCTG
CATGGTTTCCAGCGAGGGGACCTGCGCGGCGGCCTACAAGTACGGGCAATAA

Upstream 100 bases:

>100_bases
TCGTTCACGCCGGGTTCGCCATCTCCAAGCTCGACGAGGAGGATGCGCAGGAAACCCTTCGGCTGATGAGGGAAGTATTC
CGCCCGGAGGATATGGCCTG

Downstream 100 bases:

>100_bases
TTCAACAACCGGAGAACCCTGTGAACAAGGAACTCATTCTGCTCGGTCACGGCAGTGGCGGAAAGCTATCCCACCAACTC
CTGGACGACCTCATCATCCC

Product: hydrogenase expression/formation protein HypD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 363

Protein sequence:

>363_residues
MNYQDEFRDRALVQGYAQRIARLVEGRTDVMTFMEVCGTHTMSIYQYGLRSLLPPQVRLISGPGCPVCVTPNEYLDRAVA
LCRLPGVIVATFGDMVRVPGSSSSLQEERAMGADVRIVYSPLDAVALAAANPDRKVVFLGVGFETTAPAIGGSILAARKQ
GLANYFVLAAHKTMPIPMRVLANDPELGIDGYLCPAHVSTIIGADAYRFLPEEFGIPCVVTGFEPVDVMQGVEMLVRQVV
EGKPRVEIQYSRVATWEGNRKALDVLAQVFTPFDAPWRGIGIIPGSGLRIADAYAAFDAEREIAVEVEETKEHQGCLCGE
ILKGKVTPFDCPLFANACTPESPVGACMVSSEGTCAAAYKYGQ

Sequences:

>Translated_363_residues
MNYQDEFRDRALVQGYAQRIARLVEGRTDVMTFMEVCGTHTMSIYQYGLRSLLPPQVRLISGPGCPVCVTPNEYLDRAVA
LCRLPGVIVATFGDMVRVPGSSSSLQEERAMGADVRIVYSPLDAVALAAANPDRKVVFLGVGFETTAPAIGGSILAARKQ
GLANYFVLAAHKTMPIPMRVLANDPELGIDGYLCPAHVSTIIGADAYRFLPEEFGIPCVVTGFEPVDVMQGVEMLVRQVV
EGKPRVEIQYSRVATWEGNRKALDVLAQVFTPFDAPWRGIGIIPGSGLRIADAYAAFDAEREIAVEVEETKEHQGCLCGE
ILKGKVTPFDCPLFANACTPESPVGACMVSSEGTCAAAYKYGQ
>Mature_363_residues
MNYQDEFRDRALVQGYAQRIARLVEGRTDVMTFMEVCGTHTMSIYQYGLRSLLPPQVRLISGPGCPVCVTPNEYLDRAVA
LCRLPGVIVATFGDMVRVPGSSSSLQEERAMGADVRIVYSPLDAVALAAANPDRKVVFLGVGFETTAPAIGGSILAARKQ
GLANYFVLAAHKTMPIPMRVLANDPELGIDGYLCPAHVSTIIGADAYRFLPEEFGIPCVVTGFEPVDVMQGVEMLVRQVV
EGKPRVEIQYSRVATWEGNRKALDVLAQVFTPFDAPWRGIGIIPGSGLRIADAYAAFDAEREIAVEVEETKEHQGCLCGE
ILKGKVTPFDCPLFANACTPESPVGACMVSSEGTCAAAYKYGQ

Specific function: Required For The Formation Of All Three Hydrogenase Isoenzymes. [C]

COG id: COG0409

COG function: function code O; Hydrogenase maturation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hypD family [H]

Homologues:

Organism=Escherichia coli, GI1789084, Length=368, Percent_Identity=44.8369565217391, Blast_Score=322, Evalue=2e-89,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002780 [H]

Pfam domain/function: PF01924 HypD [H]

EC number: NA

Molecular weight: Translated: 39219; Mature: 39219

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.3 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
3.3 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYQDEFRDRALVQGYAQRIARLVEGRTDVMTFMEVCGTHTMSIYQYGLRSLLPPQVRLI
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEE
SGPGCPVCVTPNEYLDRAVALCRLPGVIVATFGDMVRVPGSSSSLQEERAMGADVRIVYS
ECCCCCEEECCHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCHHHHHHHCCCCEEEEEC
PLDAVALAAANPDRKVVFLGVGFETTAPAIGGSILAARKQGLANYFVLAAHKTMPIPMRV
CCCHHEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCEEE
LANDPELGIDGYLCPAHVSTIIGADAYRFLPEEFGIPCVVTGFEPVDVMQGVEMLVRQVV
ECCCCCCCCCCEECHHHHHHHHCCHHHHHCHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
EGKPRVEIQYSRVATWEGNRKALDVLAQVFTPFDAPWRGIGIIPGSGLRIADAYAAFDAE
CCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEHHHHHHCCC
REIAVEVEETKEHQGCLCGEILKGKVTPFDCPLFANACTPESPVGACMVSSEGTCAAAYK
CEEEEEEHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEE
YGQ
CCC
>Mature Secondary Structure
MNYQDEFRDRALVQGYAQRIARLVEGRTDVMTFMEVCGTHTMSIYQYGLRSLLPPQVRLI
CCCHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEE
SGPGCPVCVTPNEYLDRAVALCRLPGVIVATFGDMVRVPGSSSSLQEERAMGADVRIVYS
ECCCCCEEECCHHHHHHHHHHHHCCCEEEEECCCCEECCCCCCHHHHHHHCCCCEEEEEC
PLDAVALAAANPDRKVVFLGVGFETTAPAIGGSILAARKQGLANYFVLAAHKTMPIPMRV
CCCHHEEECCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHCCCEEEEEEECCCCCCCEEE
LANDPELGIDGYLCPAHVSTIIGADAYRFLPEEFGIPCVVTGFEPVDVMQGVEMLVRQVV
ECCCCCCCCCCEECHHHHHHHHCCHHHHHCHHHCCCCEEEECCCHHHHHHHHHHHHHHHH
EGKPRVEIQYSRVATWEGNRKALDVLAQVFTPFDAPWRGIGIIPGSGLRIADAYAAFDAE
CCCCCEEEEEEEEEECCCCHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEEHHHHHHCCC
REIAVEVEETKEHQGCLCGEILKGKVTPFDCPLFANACTPESPVGACMVSSEGTCAAAYK
CEEEEEEHHHHCCCCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEEEEE
YGQ
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8497190 [H]