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The map label for this gene is fabH-1 [H]

Identifier: 39995399

GI number: 39995399

Start: 319532

End: 320512

Strand: Direct

Name: fabH-1 [H]

Synonym: GSU0290

Alternate gene names: 39995399

Gene position: 319532-320512 (Clockwise)

Preceding gene: 39995398

Following gene: 39995401

Centisome position: 8.38

GC content: 60.86

Gene sequence:

>981_bases
ATGTTTCATTCAATCGTCCTTGCCACCGGCGGCCAGGTTCCCGAGCGGGTGGTCCCCAATTCCCATTTCTCATACCTGGT
CGACGACGCCGACACGTGGATCCAGTCCCGAACCGGCATTCGGGAGCGCCGGTTCGCCGCTCCAGACGAGGCCACGTCCG
ATCTGGCCACTGCCGCGGCCCTCAAGGCCCTTGACCGTGCCGGCATGGGGGCAGGGGAGCTCGACTGCCTCATCGTGGCC
ACGTCCACGCCCGACATGTGCCTGCCGGCCACGGCATGCATGGTCCAGAAAAATATCGGTGCCGTGAATGCCTTTGCCTT
CGATATGAATGCAGTCTGCAGCGGGTTCGTCTTCGGGCTGGAAACGGCAGACAACTTCATCCGGTCCGGCAAATACGAAC
GGGTCATGGTGATCGGCGCCGACACCTACTCGAAGATTCTCGATTTTCAGGACCAGACCACCTGCCCCCTGTTCGGTGAC
GGGGCCGGCGCGGTTATTCTGGGAAGGACCACCGAGCGCACCGGTATCCTCCAGAGTGTCATCCGGAGCGACGGCAGCGG
CTGGGAACTGATTCAGGTGCCCTCGTCGGGGTCCCGCAAGCCGGTGACCGCCGAGACCATCGCCCTGAGGGAAAATTCCT
TCCGCATGGCTGGGAAGCAGGTCTTTATCTTCGCCACCGACGTAATTCCTCAGATTATCGAGGAAGTGACGACAAAAGCC
GGGGTGGCGGTGACCGATCTGGACCACATAATTCCGCACCAGGCCAATTATCGGATCATCGACTTCATTTCCCGCAAGAC
CGGTATTCCCAAAGAACGTTTTCTTCTAAACCTGGATCGCTACGGTAACACGGCCGCTGCGTCGGTTGGGCTCGCGCTGG
ACGAATACCTGCGCAATGGCACCATCAAGCCGGGGGAACTCGTTCTCATGATGGGGTTCGGCGGCGGGCTTTCCTGGGGG
GGGATCCTCATCAGGGCCTGA

Upstream 100 bases:

>100_bases
TAATTGCTTTGACATTTGATCGTGAAATGTGAGATATTTCGAGGAATTATCAAGTAGCCCCGGCGGGGGGTTCCGTGTTT
CACGGGGAGCGGAGAGTCTC

Downstream 100 bases:

>100_bases
CCCCGGCAACGCCCTCCCCCACGGTGAGTACGGTGAGCCCCGCGCCGCGCAGCATCTCTTCCAGCATGGCGGCGGGGACC
CGCCGCTTCCATCCCTCGTG

Product: 3-oxoacyl-ACP synthase

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase III; Beta-ketoacyl-ACP synthase III; KAS III [H]

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MFHSIVLATGGQVPERVVPNSHFSYLVDDADTWIQSRTGIRERRFAAPDEATSDLATAAALKALDRAGMGAGELDCLIVA
TSTPDMCLPATACMVQKNIGAVNAFAFDMNAVCSGFVFGLETADNFIRSGKYERVMVIGADTYSKILDFQDQTTCPLFGD
GAGAVILGRTTERTGILQSVIRSDGSGWELIQVPSSGSRKPVTAETIALRENSFRMAGKQVFIFATDVIPQIIEEVTTKA
GVAVTDLDHIIPHQANYRIIDFISRKTGIPKERFLLNLDRYGNTAAASVGLALDEYLRNGTIKPGELVLMMGFGGGLSWG
GILIRA

Sequences:

>Translated_326_residues
MFHSIVLATGGQVPERVVPNSHFSYLVDDADTWIQSRTGIRERRFAAPDEATSDLATAAALKALDRAGMGAGELDCLIVA
TSTPDMCLPATACMVQKNIGAVNAFAFDMNAVCSGFVFGLETADNFIRSGKYERVMVIGADTYSKILDFQDQTTCPLFGD
GAGAVILGRTTERTGILQSVIRSDGSGWELIQVPSSGSRKPVTAETIALRENSFRMAGKQVFIFATDVIPQIIEEVTTKA
GVAVTDLDHIIPHQANYRIIDFISRKTGIPKERFLLNLDRYGNTAAASVGLALDEYLRNGTIKPGELVLMMGFGGGLSWG
GILIRA
>Mature_326_residues
MFHSIVLATGGQVPERVVPNSHFSYLVDDADTWIQSRTGIRERRFAAPDEATSDLATAAALKALDRAGMGAGELDCLIVA
TSTPDMCLPATACMVQKNIGAVNAFAFDMNAVCSGFVFGLETADNFIRSGKYERVMVIGADTYSKILDFQDQTTCPLFGD
GAGAVILGRTTERTGILQSVIRSDGSGWELIQVPSSGSRKPVTAETIALRENSFRMAGKQVFIFATDVIPQIIEEVTTKA
GVAVTDLDHIIPHQANYRIIDFISRKTGIPKERFLLNLDRYGNTAAASVGLALDEYLRNGTIKPGELVLMMGFGGGLSWG
GILIRA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the

COG id: COG0332

COG function: function code I; 3-oxoacyl-[acyl-carrier-protein] synthase III

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabH family [H]

Homologues:

Organism=Escherichia coli, GI1787333, Length=326, Percent_Identity=38.6503067484663, Blast_Score=251, Evalue=4e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013751
- InterPro:   IPR013747
- InterPro:   IPR004655
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF08545 ACP_syn_III; PF08541 ACP_syn_III_C [H]

EC number: =2.3.1.41 [H]

Molecular weight: Translated: 35062; Mature: 35062

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFHSIVLATGGQVPERVVPNSHFSYLVDDADTWIQSRTGIRERRFAAPDEATSDLATAAA
CCCEEEEECCCCCCHHHCCCCCCEEEECCHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHH
LKALDRAGMGAGELDCLIVATSTPDMCLPATACMVQKNIGAVNAFAFDMNAVCSGFVFGL
HHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHEEEH
ETADNFIRSGKYERVMVIGADTYSKILDFQDQTTCPLFGDGAGAVILGRTTERTGILQSV
HHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHH
IRSDGSGWELIQVPSSGSRKPVTAETIALRENSFRMAGKQVFIFATDVIPQIIEEVTTKA
HHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEECCCEEEEEEHHHHHHHHHHHHHHC
GVAVTDLDHIIPHQANYRIIDFISRKTGIPKERFLLNLDRYGNTAAASVGLALDEYLRNG
CEEEEHHHHHCCCCCCCEEEEEHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHHHHHHCC
TIKPGELVLMMGFGGGLSWGGILIRA
CCCCCCEEEEEECCCCCCCCEEEEEC
>Mature Secondary Structure
MFHSIVLATGGQVPERVVPNSHFSYLVDDADTWIQSRTGIRERRFAAPDEATSDLATAAA
CCCEEEEECCCCCCHHHCCCCCCEEEECCHHHHHHHHCCCHHHHCCCCCCHHHHHHHHHH
LKALDRAGMGAGELDCLIVATSTPDMCLPATACMVQKNIGAVNAFAFDMNAVCSGFVFGL
HHHHHHCCCCCCCEEEEEEEECCCCCHHHHHHHHHHHCCCEEEEEEECHHHHHHHHEEEH
ETADNFIRSGKYERVMVIGADTYSKILDFQDQTTCPLFGDGAGAVILGRTTERTGILQSV
HHHHHHHHCCCCCEEEEEECCHHHHHHCCCCCCCCCEEECCCCEEEEECCCHHHHHHHHH
IRSDGSGWELIQVPSSGSRKPVTAETIALRENSFRMAGKQVFIFATDVIPQIIEEVTTKA
HHCCCCCEEEEECCCCCCCCCCCCEEEEEECCCEEECCCEEEEEEHHHHHHHHHHHHHHC
GVAVTDLDHIIPHQANYRIIDFISRKTGIPKERFLLNLDRYGNTAAASVGLALDEYLRNG
CEEEEHHHHHCCCCCCCEEEEEHHHHCCCCHHHEEEEECCCCCHHHHHHHHHHHHHHHCC
TIKPGELVLMMGFGGGLSWGGILIRA
CCCCCCEEEEEECCCCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA