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The map label for this gene is hupC [H]

Identifier: 39995232

GI number: 39995232

Start: 134859

End: 135527

Strand: Reverse

Name: hupC [H]

Synonym: GSU0121

Alternate gene names: 39995232

Gene position: 135527-134859 (Counterclockwise)

Preceding gene: 39995233

Following gene: 308513279

Centisome position: 3.55

GC content: 61.88

Gene sequence:

>669_bases
ATGGCACGGAACCGGAATTGTCTCTACGAGGAGTACGTCTGGGAGGTCCCGGTGCGGGTGACCCACTGGGTCAACATGCT
CGCCATCGTCGTGCTGTCGGTGACCGGCATTTACATCGGATCGCCCAAGACCCTGGGACTCTCCGCCTCTGACTATGTCA
TGGGCTGGGTCCGCGTCATCCACTTCACGGCGGGCTACACCTTTGCCGTAAGCGTCGCGAGCCGGATGTGGTGGGCCTTT
GCCGGCAATCGTCACGCGGGATGGTGTGAATTCGTCCCGTTCCTCTACCCGGAGGGTCGCCGGAACATGTGGCGGATGTT
CACCTACTACACCTTCCTCTCCCGGAAGGTCCCGCACCCCATCGGCCACAATGCCCTGGCGGGCGCCACCTACCTTCTGG
TCTTCCTGCTCTACCTGACCATGATCTTCACCGGGCTCGCCCTCTATGCCGAGCACCGCCCCGGCGGCGCCATGCACGTG
CTCCTTTCGCCCCTCTACTGGCTGTTCAGTAACCAGGGGATGCGCCTGACCCACCATATGGTCATGTGGCTTCTCATCGC
CTTTGCTATCCACCATGTGTACAGCGCGTGGCTCATGGACGTGAAGGAACGCGGCGGCGTCATGTCGAGCATTTTCGGCG
GCTACAAGCCGGTGAAGCGGAGGGAGTAA

Upstream 100 bases:

>100_bases
GACCATCCACTCCTTCGACCCGTGCTTGGCCTGCGCCGTGCACGTGGTCGACCCGAAAGGAGGAGAACTGGTCAGCGTGA
AGGTCCTGTAGGAGGAATTC

Downstream 100 bases:

>100_bases
CCGCTGAGCATCCTGGTTCTCGGCATAGGAAACCTCATCATGTCCGATGACGGCGCCGGCGTGCGGGCGGTGGAACTGAT
CCGGGAACTCCATCCCTTGC

Product: nickel-iron hydrogenase, b-type cytochrome subunit

Products: oxidized ferredoxin; H2 [C]

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 221

Protein sequence:

>222_residues
MARNRNCLYEEYVWEVPVRVTHWVNMLAIVVLSVTGIYIGSPKTLGLSASDYVMGWVRVIHFTAGYTFAVSVASRMWWAF
AGNRHAGWCEFVPFLYPEGRRNMWRMFTYYTFLSRKVPHPIGHNALAGATYLLVFLLYLTMIFTGLALYAEHRPGGAMHV
LLSPLYWLFSNQGMRLTHHMVMWLLIAFAIHHVYSAWLMDVKERGGVMSSIFGGYKPVKRRE

Sequences:

>Translated_222_residues
MARNRNCLYEEYVWEVPVRVTHWVNMLAIVVLSVTGIYIGSPKTLGLSASDYVMGWVRVIHFTAGYTFAVSVASRMWWAF
AGNRHAGWCEFVPFLYPEGRRNMWRMFTYYTFLSRKVPHPIGHNALAGATYLLVFLLYLTMIFTGLALYAEHRPGGAMHV
LLSPLYWLFSNQGMRLTHHMVMWLLIAFAIHHVYSAWLMDVKERGGVMSSIFGGYKPVKRRE
>Mature_221_residues
ARNRNCLYEEYVWEVPVRVTHWVNMLAIVVLSVTGIYIGSPKTLGLSASDYVMGWVRVIHFTAGYTFAVSVASRMWWAFA
GNRHAGWCEFVPFLYPEGRRNMWRMFTYYTFLSRKVPHPIGHNALAGATYLLVFLLYLTMIFTGLALYAEHRPGGAMHVL
LSPLYWLFSNQGMRLTHHMVMWLLIAFAIHHVYSAWLMDVKERGGVMSSIFGGYKPVKRRE

Specific function: Probable b-type cytochrome [H]

COG id: COG1969

COG function: function code C; Ni,Fe-hydrogenase I cytochrome b subunit

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hupC/hyaC/hydC family [H]

Homologues:

Organism=Escherichia coli, GI1787208, Length=229, Percent_Identity=34.9344978165939, Blast_Score=130, Evalue=9e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005797
- InterPro:   IPR016174
- InterPro:   IPR000516 [H]

Pfam domain/function: PF00033 Cytochrom_B_N [H]

EC number: NA

Molecular weight: Translated: 25665; Mature: 25533

Theoretical pI: Translated: 10.02; Mature: 10.02

Prosite motif: PS00882 NI_HGENASE_CYTB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARNRNCLYEEYVWEVPVRVTHWVNMLAIVVLSVTGIYIGSPKTLGLSASDYVMGWVRVI
CCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHH
HFTAGYTFAVSVASRMWWAFAGNRHAGWCEFVPFLYPEGRRNMWRMFTYYTFLSRKVPHP
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
IGHNALAGATYLLVFLLYLTMIFTGLALYAEHRPGGAMHVLLSPLYWLFSNQGMRLTHHM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VMWLLIAFAIHHVYSAWLMDVKERGGVMSSIFGGYKPVKRRE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
ARNRNCLYEEYVWEVPVRVTHWVNMLAIVVLSVTGIYIGSPKTLGLSASDYVMGWVRVI
CCCCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHH
HFTAGYTFAVSVASRMWWAFAGNRHAGWCEFVPFLYPEGRRNMWRMFTYYTFLSRKVPHP
HHHCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCC
IGHNALAGATYLLVFLLYLTMIFTGLALYAEHRPGGAMHVLLSPLYWLFSNQGMRLTHHM
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCHHHHHH
VMWLLIAFAIHHVYSAWLMDVKERGGVMSSIFGGYKPVKRRE
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Reduced ferredoxin; 2 H+ [C]

Specific reaction: Reduced ferredoxin + 2 H+ = 2 oxidized ferredoxin + H2 [C]

General reaction: Oxidoreductases [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 2094292; 3067084; 1791762 [H]