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The map label for this gene is atpD [H]

Identifier: 39995224

GI number: 39995224

Start: 127605

End: 129017

Strand: Direct

Name: atpD [H]

Synonym: GSU0113

Alternate gene names: 39995224

Gene position: 127605-129017 (Clockwise)

Preceding gene: 39995223

Following gene: 39995225

Centisome position: 3.35

GC content: 60.86

Gene sequence:

>1413_bases
ATGAGTCAGAACTTCGGTAAAATTTCGCAGGTCATCGGCGCGGTTATTGACGTCGAGTTTGAGCCGGGCAAACTGCCTCC
CATCTACAACGCCCTCCGGGTGACCAACCCGGCCATTGACGATAAGGAATACAACTTGGTGCTCGAAGTGGCCCAGCACC
TGGGTGAAAACGCGGTCCGGACCATCGCCATGGATTCCACCGACGGTCTTGTCCGGGGCCAGGCAGTGCTCGATACCGGT
AAGCAGATTTCCGTGCCGGTGGGCCGCAAGACCCTGGGTCGAATCCTCAACGTCATCGGCGAGCCGGTGGACGAGATGGG
TCCGGTCAACGCCGAGAAAGAGTACGGAATCCACCGCGAAGCTCCCGCCTTCGTGGACCAGTCCACCAAGGTTGAAGCCT
TCACCACCGGGATCAAGGTCGTCGACCTTCTCGCTCCCTACGCTCGGGGCGGCAAGATTGGCCTCTTCGGCGGCGCCGGC
GTCGGCAAGACCGTTCTCATCATGGAGCTCATCAACAACATCGCCAAGCAGCACGGTGGCTTCTCCGTGTTTGCCGGCGT
CGGTGAGCGGACCCGCGAAGGAAACGATCTCTGGATGGAGATGAAGGAGTCCGGGGTTCTCGACAAGGCCGCCCTCGTCT
ACGGCCAGATGAACGAGCCGCCGGGAGCACGTGCCCGGGTTGCCCTCTCCGCCCTTTCCATCGCCGAGTACTTCCGTGAC
GAAGAAGGTCAGAACGTGCTTCTCTTCGTTGACAATATCTTCCGCTTCACCCAGGCGGGTTCCGAAGTTTCCGCGCTCCT
CGGCCGGATTCCCTCCGCCGTTGGTTACCAGCCCACACTGGCCACAGAGATGGGAGAGCTTCAGGAGCGAATCACCTCCA
CCACCAAGGGCTCCATTACCTCGGTTCAGGCGATCTACGTTCCGGCCGACGACCTTACCGACCCGGCTCCGGCAACCGCC
TTCGCCCACCTGGACGCAACGACCGTTCTTTCCCGTCAGATTGCCGAGCTCGGTATCTACCCGGCCGTTGACCCGCTGGA
CTCCACGTCGCGGATTCTCGATCCCCAGGTAATCGGCGAGGAGCACTACTCCATTGCCCGGCAGGTCCAGTACGTGCTCC
AGAAGTACAAGGATCTCCAGGACATCATCGCTATTCTCGGTATGGACGAACTCTCCGAGGAGGACAAGCTGGTCGTTGCC
CGGGCCCGGAAGATCCAGCGTTTCCTCTCCCAGCCGTTCCACGTTGCCGAAGCCTTCACCGGCAGCCCCGGCAAGTACGT
TGAGCTGAAGGACACCATCAAGGGCTTCCAGGAGATCGTCGCCGGCAAGCATGACGATGTCCCCGAGCAGGCCTTCTACA
TGGTCGGAACCATTGAAGAGGCCCTCGAAAAGGCCAAGAAGCTCGCTGCCTAA

Upstream 100 bases:

>100_bases
GCTCATGGAGATTATCTCCGGTGCCGAGTCGATCAAGGGCTAAGCAATCTCACGATTATAAAATAGAGGCCCGGCACGGG
CCGCAGGAGGAAGAGGCACC

Downstream 100 bases:

>100_bases
GGATTTATATGACCTCGTCGCGGGGGAGGATGGTATCCCCCGCATAAAGGACTACGATAGATGGCTGAAAAACTGAAAGT
CGATCTGGTTACCCCTTATA

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta 1; F-ATPase subunit beta 1 [H]

Number of amino acids: Translated: 470; Mature: 469

Protein sequence:

>470_residues
MSQNFGKISQVIGAVIDVEFEPGKLPPIYNALRVTNPAIDDKEYNLVLEVAQHLGENAVRTIAMDSTDGLVRGQAVLDTG
KQISVPVGRKTLGRILNVIGEPVDEMGPVNAEKEYGIHREAPAFVDQSTKVEAFTTGIKVVDLLAPYARGGKIGLFGGAG
VGKTVLIMELINNIAKQHGGFSVFAGVGERTREGNDLWMEMKESGVLDKAALVYGQMNEPPGARARVALSALSIAEYFRD
EEGQNVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGELQERITSTTKGSITSVQAIYVPADDLTDPAPATA
FAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPQVIGEEHYSIARQVQYVLQKYKDLQDIIAILGMDELSEEDKLVVA
RARKIQRFLSQPFHVAEAFTGSPGKYVELKDTIKGFQEIVAGKHDDVPEQAFYMVGTIEEALEKAKKLAA

Sequences:

>Translated_470_residues
MSQNFGKISQVIGAVIDVEFEPGKLPPIYNALRVTNPAIDDKEYNLVLEVAQHLGENAVRTIAMDSTDGLVRGQAVLDTG
KQISVPVGRKTLGRILNVIGEPVDEMGPVNAEKEYGIHREAPAFVDQSTKVEAFTTGIKVVDLLAPYARGGKIGLFGGAG
VGKTVLIMELINNIAKQHGGFSVFAGVGERTREGNDLWMEMKESGVLDKAALVYGQMNEPPGARARVALSALSIAEYFRD
EEGQNVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGELQERITSTTKGSITSVQAIYVPADDLTDPAPATA
FAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPQVIGEEHYSIARQVQYVLQKYKDLQDIIAILGMDELSEEDKLVVA
RARKIQRFLSQPFHVAEAFTGSPGKYVELKDTIKGFQEIVAGKHDDVPEQAFYMVGTIEEALEKAKKLAA
>Mature_469_residues
SQNFGKISQVIGAVIDVEFEPGKLPPIYNALRVTNPAIDDKEYNLVLEVAQHLGENAVRTIAMDSTDGLVRGQAVLDTGK
QISVPVGRKTLGRILNVIGEPVDEMGPVNAEKEYGIHREAPAFVDQSTKVEAFTTGIKVVDLLAPYARGGKIGLFGGAGV
GKTVLIMELINNIAKQHGGFSVFAGVGERTREGNDLWMEMKESGVLDKAALVYGQMNEPPGARARVALSALSIAEYFRDE
EGQNVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGELQERITSTTKGSITSVQAIYVPADDLTDPAPATAF
AHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPQVIGEEHYSIARQVQYVLQKYKDLQDIIAILGMDELSEEDKLVVAR
ARKIQRFLSQPFHVAEAFTGSPGKYVELKDTIKGFQEIVAGKHDDVPEQAFYMVGTIEEALEKAKKLAA

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=470, Percent_Identity=75.531914893617, Blast_Score=712, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=401, Percent_Identity=26.6832917705736, Blast_Score=114, Evalue=2e-25,
Organism=Homo sapiens, GI19913426, Length=401, Percent_Identity=26.4339152119701, Blast_Score=112, Evalue=5e-25,
Organism=Homo sapiens, GI19913424, Length=300, Percent_Identity=28, Blast_Score=105, Evalue=7e-23,
Organism=Homo sapiens, GI50345984, Length=298, Percent_Identity=25.503355704698, Blast_Score=98, Evalue=1e-20,
Organism=Homo sapiens, GI4757810, Length=298, Percent_Identity=25.503355704698, Blast_Score=98, Evalue=1e-20,
Organism=Escherichia coli, GI1790170, Length=463, Percent_Identity=70.6263498920086, Blast_Score=653, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=313, Percent_Identity=32.9073482428115, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI1790172, Length=318, Percent_Identity=26.4150943396226, Blast_Score=113, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=470, Percent_Identity=71.9148936170213, Blast_Score=683, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17510931, Length=353, Percent_Identity=27.1954674220963, Blast_Score=123, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=405, Percent_Identity=25.1851851851852, Blast_Score=119, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17565854, Length=298, Percent_Identity=27.8523489932886, Blast_Score=112, Evalue=4e-25,
Organism=Caenorhabditis elegans, GI71988080, Length=298, Percent_Identity=25.503355704698, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988063, Length=298, Percent_Identity=25.503355704698, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI71988074, Length=266, Percent_Identity=24.0601503759398, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322581, Length=462, Percent_Identity=73.8095238095238, Blast_Score=696, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=432, Percent_Identity=27.3148148148148, Blast_Score=120, Evalue=7e-28,
Organism=Saccharomyces cerevisiae, GI6319370, Length=365, Percent_Identity=25.7534246575342, Blast_Score=108, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320016, Length=263, Percent_Identity=24.7148288973384, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI24638766, Length=470, Percent_Identity=75.7446808510638, Blast_Score=711, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=471, Percent_Identity=69.8513800424628, Blast_Score=650, Evalue=0.0,
Organism=Drosophila melanogaster, GI24638768, Length=96, Percent_Identity=66.6666666666667, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI281361666, Length=390, Percent_Identity=26.9230769230769, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24646341, Length=390, Percent_Identity=26.9230769230769, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI17136796, Length=390, Percent_Identity=26.9230769230769, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI20129479, Length=298, Percent_Identity=27.5167785234899, Blast_Score=108, Evalue=9e-24,
Organism=Drosophila melanogaster, GI24583992, Length=301, Percent_Identity=26.2458471760797, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24583988, Length=298, Percent_Identity=27.1812080536913, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583986, Length=298, Percent_Identity=27.1812080536913, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24583984, Length=298, Percent_Identity=27.1812080536913, Blast_Score=105, Evalue=8e-23,
Organism=Drosophila melanogaster, GI24658560, Length=298, Percent_Identity=25.503355704698, Blast_Score=100, Evalue=2e-21,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50974; Mature: 50843

Theoretical pI: Translated: 4.70; Mature: 4.70

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSQNFGKISQVIGAVIDVEFEPGKLPPIYNALRVTNPAIDDKEYNLVLEVAQHLGENAVR
CCCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHE
TIAMDSTDGLVRGQAVLDTGKQISVPVGRKTLGRILNVIGEPVDEMGPVNAEKEYGIHRE
EEEECCCCCCEECHHHHCCCCEEECCCCHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCC
APAFVDQSTKVEAFTTGIKVVDLLAPYARGGKIGLFGGAGVGKTVLIMELINNIAKQHGG
CCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
FSVFAGVGERTREGNDLWMEMKESGVLDKAALVYGQMNEPPGARARVALSALSIAEYFRD
EEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
EEGQNVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGELQERITSTTKGSIT
CCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCE
SVQAIYVPADDLTDPAPATAFAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPQVIGE
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHCH
EHYSIARQVQYVLQKYKDLQDIIAILGMDELSEEDKLVVARARKIQRFLSQPFHVAEAFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHC
GSPGKYVELKDTIKGFQEIVAGKHDDVPEQAFYMVGTIEEALEKAKKLAA
CCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SQNFGKISQVIGAVIDVEFEPGKLPPIYNALRVTNPAIDDKEYNLVLEVAQHLGENAVR
CCCHHHHHHHHHHHHEEEECCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCHHHE
TIAMDSTDGLVRGQAVLDTGKQISVPVGRKTLGRILNVIGEPVDEMGPVNAEKEYGIHRE
EEEECCCCCCEECHHHHCCCCEEECCCCHHHHHHHHHHHCCCHHHHCCCCCHHHCCCCCC
APAFVDQSTKVEAFTTGIKVVDLLAPYARGGKIGLFGGAGVGKTVLIMELINNIAKQHGG
CCHHHCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCC
FSVFAGVGERTREGNDLWMEMKESGVLDKAALVYGQMNEPPGARARVALSALSIAEYFRD
EEEEECCCCCCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCC
EEGQNVLLFVDNIFRFTQAGSEVSALLGRIPSAVGYQPTLATEMGELQERITSTTKGSIT
CCCCEEEEEHHHHHHHHHCCHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHHCCCCCCE
SVQAIYVPADDLTDPAPATAFAHLDATTVLSRQIAELGIYPAVDPLDSTSRILDPQVIGE
EEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCHHHHCH
EHYSIARQVQYVLQKYKDLQDIIAILGMDELSEEDKLVVARARKIQRFLSQPFHVAEAFT
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCHHHHHHHC
GSPGKYVELKDTIKGFQEIVAGKHDDVPEQAFYMVGTIEEALEKAKKLAA
CCCCCEEEHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA