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The map label for this gene is hdrA2 [H]

Identifier: 39995201

GI number: 39995201

Start: 100519

End: 102516

Strand: Reverse

Name: hdrA2 [H]

Synonym: GSU0090

Alternate gene names: 39995201

Gene position: 102516-100519 (Counterclockwise)

Preceding gene: 39995202

Following gene: 39995200

Centisome position: 2.69

GC content: 64.26

Gene sequence:

>1998_bases
ATGTCCCGAATCGGCGTATTTGTCTGCCATTGCGGCGAAAACATCTCCCGTACCGTTGACGTGGAGCGCGTGGCCGGGGA
ACTGGCCAAGGTTCCCGGCGTCGCTTTTGCCACCGACTACAAGTATATGTGCTCCGATCCGGGGCAGGGCCTATTGAAGA
AGGCGGTGGCCGAGCACCGGCTCGACGGTGTCGTGGTGGCGGCCTGCTCTCCCCGGATGCATGAAAAGACCTTTCGCACC
GCGGCCAAGGCGGCCGGCCTGAACCCCTTCCTCTGCGAGATGGCCAACATCCGCGAACACTGTTCCTGGGTTCACGAGGA
CCGGGACGAGGCAACCGCCAAGGCCATCTCCATTGTGGAGATGATGGTGGCCCGCGTCAAAAAGGACCGGCGGCTCGTGC
CGATCACCGTACCGGTCACCAAGCGGGCCCTGGTCATCGGCGGCGGCATCGCCGGCATCCAGGCGGCCCTGGATATAGCC
GACGCGGGCCACAAGGTGGTGCTCGTGGAGCGGGAGCCCTCCATCGGCGGGCACATGGCCCAGCTCTCCGAGACCTTTCC
CACCCTGGACTGTTCCCAGTGCATCATGACCCCCAAGATGGTGGATGTGGCCAACCACCCCAACATAACCCTCCACACCT
ACAGCGAAATCGAGAGCGTTGACGGCTACATCGGCAATTTCCAGGTGACCATCCGGAAGAAGGCCCGCTCCGTGGACGAG
TCAAAATGCACCGGCTGCGGGGTCTGCATGGCCAAGTGTCCCCAGAAGAAGATCCCGAACAGTTTCGACAAGAACCTGGG
GATGCGCCCCGCCATCTACGTCCCCTTCCCCCAGGCTGTGCCCAACACGCCGGTCATCGACCGGGAAAACTGCACCTATT
TCAAGTCTGGCAAATGTGGCGTCTGCGCCAAGGTCTGCGGCCCCCGGGCCGTGGACTACGAACAGCAGGACCAGCTCATC
GTCGAGCCGGCCGGAGCCATCGTGGTTGCCACCGGCTTTTCGCTCTACGACATCGGCCCCAAGCCGGCCGGCTCCCCCAT
CGAGGGGTACGGCGAGTTCGGCTACGGCACCATCCCCGACGTGATCGACGGGCTCACCTTCGAGCGGCTTGCCTCCGCCT
CGGGCCCCACGGGGGGCAAGATCGTCCGCCCCTCCGACGGGAAGGAGCCGAAACAGGTGGTCTTTGTCCAGTGCGTCGGC
TCACGGGCCCGCGAAAAGGGGATCTCCTACTGTTCCAAGATCTGCTGCATGTACACGGCAAAGCACACCATGCTCTACAA
GCACAAGGTGCACGACGGCCAGGCCTATGTCTTCTTCATGGACGCGCGGACGCCGGGTAAGAACTACGACGAGTTCTGGC
GCCGGGCCATCGAGGAAGAGGAGGCGGTCTACATCAGGGGAATGGTCTCCCGCCTCTACCAGAAGGGGGACAAGGTGGTG
GTCATGGGGAGCGACGTCCATGTGGGTGTCCAGGTGGAGATCGAGGCGGACCTGGTGGTGCTCGCCACCGCCGTGCAGGC
GCGGGAGGGGGCCGACTCCCTCGCCCAGAAGCTCGGCATCTCCTATGACAACTACAACTTCTACTCCGAGGCCCACGCCA
AGCTCAAGCCCGTGGAGTGCGCCACCGCCGGGGTCTATCTGGCCGGGGCCTGCCAGGGGCCCAAGGACATCCCCGACACC
GTCAGCCAGGCGTCGGCTGCAGCGGCAAAGGTCATGACCCTCTTCGCCCGCGACGAGCTGGAGCGTGAGCCCATCGTGGC
CAAGGTGGACGAGCGGCGCTGCGTTGCCTGCCTCTACTGCAAGAAGATCTGCCCCTACGGTGCCGTGGAGGAGAAGGAGA
TCCGCGACCGCCAGGGGAATCTGATCCGGGTCGTGGCTTACGTGAACCCGGGGGTCTGCGGCGGCTGCGGCACCTGCCAG
GCCACCTGCCCTTCAAAAAGCGTGGAGCTGGATGGCTACACCGACGAGCAGATCATGGCCATGATCGAGGTGCTCTAA

Upstream 100 bases:

>100_bases
GCTCCTGGCCCTGGCGGTAGGGGTTGCGCCGGCGAAGCTCGGGTTCGACAGCATGATCGTCAATCCCCTGCCGCTTCTGA
AAGAGAAAGGGTTGGTCTAG

Downstream 100 bases:

>100_bases
TGCACATACACAAAGAGAAACACGCTTTCGAACCCAAGATCGTTGCCTTTGTCTGCACCTGGTGCACCTATGCCGGCGCC
GACCTGGCCGGGACCTCGCG

Product: heterodisulfide reductase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 665; Mature: 664

Protein sequence:

>665_residues
MSRIGVFVCHCGENISRTVDVERVAGELAKVPGVAFATDYKYMCSDPGQGLLKKAVAEHRLDGVVVAACSPRMHEKTFRT
AAKAAGLNPFLCEMANIREHCSWVHEDRDEATAKAISIVEMMVARVKKDRRLVPITVPVTKRALVIGGGIAGIQAALDIA
DAGHKVVLVEREPSIGGHMAQLSETFPTLDCSQCIMTPKMVDVANHPNITLHTYSEIESVDGYIGNFQVTIRKKARSVDE
SKCTGCGVCMAKCPQKKIPNSFDKNLGMRPAIYVPFPQAVPNTPVIDRENCTYFKSGKCGVCAKVCGPRAVDYEQQDQLI
VEPAGAIVVATGFSLYDIGPKPAGSPIEGYGEFGYGTIPDVIDGLTFERLASASGPTGGKIVRPSDGKEPKQVVFVQCVG
SRAREKGISYCSKICCMYTAKHTMLYKHKVHDGQAYVFFMDARTPGKNYDEFWRRAIEEEEAVYIRGMVSRLYQKGDKVV
VMGSDVHVGVQVEIEADLVVLATAVQAREGADSLAQKLGISYDNYNFYSEAHAKLKPVECATAGVYLAGACQGPKDIPDT
VSQASAAAAKVMTLFARDELEREPIVAKVDERRCVACLYCKKICPYGAVEEKEIRDRQGNLIRVVAYVNPGVCGGCGTCQ
ATCPSKSVELDGYTDEQIMAMIEVL

Sequences:

>Translated_665_residues
MSRIGVFVCHCGENISRTVDVERVAGELAKVPGVAFATDYKYMCSDPGQGLLKKAVAEHRLDGVVVAACSPRMHEKTFRT
AAKAAGLNPFLCEMANIREHCSWVHEDRDEATAKAISIVEMMVARVKKDRRLVPITVPVTKRALVIGGGIAGIQAALDIA
DAGHKVVLVEREPSIGGHMAQLSETFPTLDCSQCIMTPKMVDVANHPNITLHTYSEIESVDGYIGNFQVTIRKKARSVDE
SKCTGCGVCMAKCPQKKIPNSFDKNLGMRPAIYVPFPQAVPNTPVIDRENCTYFKSGKCGVCAKVCGPRAVDYEQQDQLI
VEPAGAIVVATGFSLYDIGPKPAGSPIEGYGEFGYGTIPDVIDGLTFERLASASGPTGGKIVRPSDGKEPKQVVFVQCVG
SRAREKGISYCSKICCMYTAKHTMLYKHKVHDGQAYVFFMDARTPGKNYDEFWRRAIEEEEAVYIRGMVSRLYQKGDKVV
VMGSDVHVGVQVEIEADLVVLATAVQAREGADSLAQKLGISYDNYNFYSEAHAKLKPVECATAGVYLAGACQGPKDIPDT
VSQASAAAAKVMTLFARDELEREPIVAKVDERRCVACLYCKKICPYGAVEEKEIRDRQGNLIRVVAYVNPGVCGGCGTCQ
ATCPSKSVELDGYTDEQIMAMIEVL
>Mature_664_residues
SRIGVFVCHCGENISRTVDVERVAGELAKVPGVAFATDYKYMCSDPGQGLLKKAVAEHRLDGVVVAACSPRMHEKTFRTA
AKAAGLNPFLCEMANIREHCSWVHEDRDEATAKAISIVEMMVARVKKDRRLVPITVPVTKRALVIGGGIAGIQAALDIAD
AGHKVVLVEREPSIGGHMAQLSETFPTLDCSQCIMTPKMVDVANHPNITLHTYSEIESVDGYIGNFQVTIRKKARSVDES
KCTGCGVCMAKCPQKKIPNSFDKNLGMRPAIYVPFPQAVPNTPVIDRENCTYFKSGKCGVCAKVCGPRAVDYEQQDQLIV
EPAGAIVVATGFSLYDIGPKPAGSPIEGYGEFGYGTIPDVIDGLTFERLASASGPTGGKIVRPSDGKEPKQVVFVQCVGS
RAREKGISYCSKICCMYTAKHTMLYKHKVHDGQAYVFFMDARTPGKNYDEFWRRAIEEEEAVYIRGMVSRLYQKGDKVVV
MGSDVHVGVQVEIEADLVVLATAVQAREGADSLAQKLGISYDNYNFYSEAHAKLKPVECATAGVYLAGACQGPKDIPDTV
SQASAAAAKVMTLFARDELEREPIVAKVDERRCVACLYCKKICPYGAVEEKEIRDRQGNLIRVVAYVNPGVCGGCGTCQA
TCPSKSVELDGYTDEQIMAMIEVL

Specific function: Part of a complex that catalyzes the reversible reduction of CoM-S-S-CoB to the thiol-coenzymes H-S-CoM (coenzyme M) and H-S-CoB (coenzyme B). May act as the catalytic subunit [H]

COG id: COG1148

COG function: function code C; Heterodisulfide reductase, subunit A and related polyferredoxins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 4 4Fe-4S ferredoxin-type domains [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001450
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR003953
- InterPro:   IPR012285 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF00037 Fer4 [H]

EC number: =1.8.98.1 [H]

Molecular weight: Translated: 72239; Mature: 72108

Theoretical pI: Translated: 7.18; Mature: 7.18

Prosite motif: PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
4.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
7.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIGVFVCHCGENISRTVDVERVAGELAKVPGVAFATDYKYMCSDPGQGLLKKAVAEHR
CCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCHHHHHHHHHHHC
LDGVVVAACSPRMHEKTFRTAAKAAGLNPFLCEMANIREHCSWVHEDRDEATAKAISIVE
CCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MMVARVKKDRRLVPITVPVTKRALVIGGGIAGIQAALDIADAGHKVVLVEREPSIGGHMA
HHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
QLSETFPTLDCSQCIMTPKMVDVANHPNITLHTYSEIESVDGYIGNFQVTIRKKARSVDE
HHHHHCCCCCHHHHHCCCCCEEECCCCCEEEEEHHHHHHCCCCCCCEEEEEEHHHCCCCC
SKCTGCGVCMAKCPQKKIPNSFDKNLGMRPAIYVPFPQAVPNTPVIDRENCTYFKSGKCG
CCCCCCCHHHHCCCHHHCCCHHHHCCCCCCEEEECCCCCCCCCCCEECCCCCEEECCCCC
VCAKVCGPRAVDYEQQDQLIVEPAGAIVVATGFSLYDIGPKPAGSPIEGYGEFGYGTIPD
CHHHHCCCCCCCCCCCCCEEEECCCEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCHH
VIDGLTFERLASASGPTGGKIVRPSDGKEPKQVVFVQCVGSRAREKGISYCSKICCMYTA
HHCCCCHHHHHCCCCCCCCEEECCCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHH
KHTMLYKHKVHDGQAYVFFMDARTPGKNYDEFWRRAIEEEEAVYIRGMVSRLYQKGDKVV
HHHEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
VMGSDVHVGVQVEIEADLVVLATAVQAREGADSLAQKLGISYDNYNFYSEAHAKLKPVEC
EEECCEEEEEEEEEECCEEEEEHHHHHHCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCEE
ATAGVYLAGACQGPKDIPDTVSQASAAAAKVMTLFARDELEREPIVAKVDERRCVACLYC
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHH
KKICPYGAVEEKEIRDRQGNLIRVVAYVNPGVCGGCGTCQATCPSKSVELDGYTDEQIMA
HHHCCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHH
MIEVL
HHHCC
>Mature Secondary Structure 
SRIGVFVCHCGENISRTVDVERVAGELAKVPGVAFATDYKYMCSDPGQGLLKKAVAEHR
CCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCEEEECCCEEECCCCHHHHHHHHHHHC
LDGVVVAACSPRMHEKTFRTAAKAAGLNPFLCEMANIREHCSWVHEDRDEATAKAISIVE
CCCEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHH
MMVARVKKDRRLVPITVPVTKRALVIGGGIAGIQAALDIADAGHKVVLVEREPSIGGHMA
HHHHHHHCCCCEEEEECCCCCEEEEEECCHHHHHHHHHHCCCCCEEEEEECCCCCCCHHH
QLSETFPTLDCSQCIMTPKMVDVANHPNITLHTYSEIESVDGYIGNFQVTIRKKARSVDE
HHHHHCCCCCHHHHHCCCCCEEECCCCCEEEEEHHHHHHCCCCCCCEEEEEEHHHCCCCC
SKCTGCGVCMAKCPQKKIPNSFDKNLGMRPAIYVPFPQAVPNTPVIDRENCTYFKSGKCG
CCCCCCCHHHHCCCHHHCCCHHHHCCCCCCEEEECCCCCCCCCCCEECCCCCEEECCCCC
VCAKVCGPRAVDYEQQDQLIVEPAGAIVVATGFSLYDIGPKPAGSPIEGYGEFGYGTIPD
CHHHHCCCCCCCCCCCCCEEEECCCEEEEEECCEEEECCCCCCCCCCCCCCCCCCCCCHH
VIDGLTFERLASASGPTGGKIVRPSDGKEPKQVVFVQCVGSRAREKGISYCSKICCMYTA
HHCCCCHHHHHCCCCCCCCEEECCCCCCCCHHEEEEEECCCHHHHHHHHHHHHHHHHHHH
KHTMLYKHKVHDGQAYVFFMDARTPGKNYDEFWRRAIEEEEAVYIRGMVSRLYQKGDKVV
HHHEEEEEEECCCCEEEEEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCCEEE
VMGSDVHVGVQVEIEADLVVLATAVQAREGADSLAQKLGISYDNYNFYSEAHAKLKPVEC
EEECCEEEEEEEEEECCEEEEEHHHHHHCCHHHHHHHHCCCCCCCCCHHHCCCCCCCCEE
ATAGVYLAGACQGPKDIPDTVSQASAAAAKVMTLFARDELEREPIVAKVDERRCVACLYC
CCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCHHHHHHHH
KKICPYGAVEEKEIRDRQGNLIRVVAYVNPGVCGGCGTCQATCPSKSVELDGYTDEQIMA
HHHCCCCCCCHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCCCCEEECCCCHHHHHH
MIEVL
HHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9063468; 11930014 [H]