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The map label for this gene is asrB [H]

Identifier: 39995196

GI number: 39995196

Start: 96773

End: 97615

Strand: Reverse

Name: asrB [H]

Synonym: GSU0085

Alternate gene names: 39995196

Gene position: 97615-96773 (Counterclockwise)

Preceding gene: 39995198

Following gene: 39995190

Centisome position: 2.56

GC content: 64.06

Gene sequence:

>843_bases
ATGTGCGATCACAAGAACATCTACCTCCCCCACCTGGCAACGATCGAGGAAATCGTTGACGAGACCCCCGACATCCGCAC
CTTCCGGCTCGTCTTTCAGGATGAACGGGTACGGGAGCATTTTACCTTCAGGGCCGGCCAGTTTGCCGAGTACTCGGCCT
TCGGCGCCGGCGAGGCCACCTTCTGCATCGCCTCGGCCCCCACCCGGCAGGGATACATCGAGTGCTGCTTCCGGGCCGTG
GGGCGGGTCACGGAAGCATTGCGTTCCCTGGAGACCGGCGACACCATCGGTGTGCGCGGACCCTACGGCAACTCGTTTCC
CGTCGAAGAGTTCTTCGGCAAGAACCTCGTCTTCGTGGCCGGAGGTATCGCGCTGCCGCCGCTGCGGACGCTCATCTGGC
AGTGCCTGGACTGGCGGGAGAAATTCGGCGACATCACCATCGTCTACGGCGCCCGGACCGAGGCCGACCTCGTCTACAAG
CGGGAACTCAGGGAGTGGGAAGAGCGGAGCGACGTACGCCTGGTAAAGACCGTGGATCCCGGAGGGAATTCCCCCTCATG
GGACGGGCAGGTGGGCTTTGTGCCGACGGTCCTGGAGCAGGCCGCGCCAGCCGCGGACAACACCATCGCCCTGGTCTGCG
GACCGCCCGTCATGATCAAGTTCACCCTTCCCGTCCTGGAGAAACTGGGATTCGCCGACACGGCCATCTACACGACCCTG
GAGAACCGGATGAAGTGCGGTCTCGGCAAGTGCGGCCGCTGCAACGTGGGCAATGTCTATGTCTGCAAGGACGGCCCGGT
CTTCACCGCGGCCCAGGTCAAGGCCATGCCCCAGGAGTTCTGA

Upstream 100 bases:

>100_bases
CGGCTTCGGAGACAACAACCGCCCCGTGGAGCTCAAGGTAAAGGGCCAGGCATTCTCGGACCTGGCGGCAAAACTGGCGG
AAGGATAAAAGGGCTCCACC

Downstream 100 bases:

>100_bases
ACCGCGAGCGATTCTGAGCAAAAGCCCCCTGCCGTAACGTTCGGCAGGGGGCTTTTTTCGTTCCGCGACTGGCGGATGAG
GATCGGAAGAGGAGAATCTC

Product: heterodisulfide reductase, cytochrome reductase subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MCDHKNIYLPHLATIEEIVDETPDIRTFRLVFQDERVREHFTFRAGQFAEYSAFGAGEATFCIASAPTRQGYIECCFRAV
GRVTEALRSLETGDTIGVRGPYGNSFPVEEFFGKNLVFVAGGIALPPLRTLIWQCLDWREKFGDITIVYGARTEADLVYK
RELREWEERSDVRLVKTVDPGGNSPSWDGQVGFVPTVLEQAAPAADNTIALVCGPPVMIKFTLPVLEKLGFADTAIYTTL
ENRMKCGLGKCGRCNVGNVYVCKDGPVFTAAQVKAMPQEF

Sequences:

>Translated_280_residues
MCDHKNIYLPHLATIEEIVDETPDIRTFRLVFQDERVREHFTFRAGQFAEYSAFGAGEATFCIASAPTRQGYIECCFRAV
GRVTEALRSLETGDTIGVRGPYGNSFPVEEFFGKNLVFVAGGIALPPLRTLIWQCLDWREKFGDITIVYGARTEADLVYK
RELREWEERSDVRLVKTVDPGGNSPSWDGQVGFVPTVLEQAAPAADNTIALVCGPPVMIKFTLPVLEKLGFADTAIYTTL
ENRMKCGLGKCGRCNVGNVYVCKDGPVFTAAQVKAMPQEF
>Mature_280_residues
MCDHKNIYLPHLATIEEIVDETPDIRTFRLVFQDERVREHFTFRAGQFAEYSAFGAGEATFCIASAPTRQGYIECCFRAV
GRVTEALRSLETGDTIGVRGPYGNSFPVEEFFGKNLVFVAGGIALPPLRTLIWQCLDWREKFGDITIVYGARTEADLVYK
RELREWEERSDVRLVKTVDPGGNSPSWDGQVGFVPTVLEQAAPAADNTIALVCGPPVMIKFTLPVLEKLGFADTAIYTTL
ENRMKCGLGKCGRCNVGNVYVCKDGPVFTAAQVKAMPQEF

Specific function: This enzyme catalyzes the hydrogen sulfide production from sulfite. It is strictly anaerobic. It is regulated by electron acceptors rather than by cysteine [H]

COG id: COG0543

COG function: function code HC; 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI49574502, Length=198, Percent_Identity=25.7575757575758, Blast_Score=68, Evalue=1e-11,
Organism=Homo sapiens, GI47778923, Length=180, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17563926, Length=169, Percent_Identity=28.4023668639053, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17563928, Length=173, Percent_Identity=31.2138728323699, Blast_Score=70, Evalue=9e-13,
Organism=Saccharomyces cerevisiae, GI6322146, Length=182, Percent_Identity=26.3736263736264, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6323510, Length=174, Percent_Identity=28.735632183908, Blast_Score=66, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24662938, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI281366101, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24662934, Length=176, Percent_Identity=30.1136363636364, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI116007804, Length=175, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI116007806, Length=175, Percent_Identity=28, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012165
- InterPro:   IPR019480
- InterPro:   IPR017927
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR017938
- InterPro:   IPR014260 [H]

Pfam domain/function: PF10418 DHODB_Fe-S_bind; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: NA

Molecular weight: Translated: 31096; Mature: 31096

Theoretical pI: Translated: 5.06; Mature: 5.06

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCDHKNIYLPHLATIEEIVDETPDIRTFRLVFQDERVREHFTFRAGQFAEYSAFGAGEAT
CCCCCCEECCHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHCCCCCCHHHCCCCCCEE
FCIASAPTRQGYIECCFRAVGRVTEALRSLETGDTIGVRGPYGNSFPVEEFFGKNLVFVA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCEEEEE
GGIALPPLRTLIWQCLDWREKFGDITIVYGARTEADLVYKRELREWEERSDVRLVKTVDP
CCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECC
GGNSPSWDGQVGFVPTVLEQAAPAADNTIALVCGPPVMIKFTLPVLEKLGFADTAIYTTL
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEEHHHHHHCCCCHHHHHHHH
ENRMKCGLGKCGRCNVGNVYVCKDGPVFTAAQVKAMPQEF
HHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHHCCCCCC
>Mature Secondary Structure
MCDHKNIYLPHLATIEEIVDETPDIRTFRLVFQDERVREHFTFRAGQFAEYSAFGAGEAT
CCCCCCEECCHHHHHHHHHCCCCCCEEEEEEECHHHHHHHHHHCCCCCCHHHCCCCCCEE
FCIASAPTRQGYIECCFRAVGRVTEALRSLETGDTIGVRGPYGNSFPVEEFFGKNLVFVA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHHHHCCCEEEEE
GGIALPPLRTLIWQCLDWREKFGDITIVYGARTEADLVYKRELREWEERSDVRLVKTVDP
CCCCCCHHHHHHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHHHCCCEEEEEEECC
GGNSPSWDGQVGFVPTVLEQAAPAADNTIALVCGPPVMIKFTLPVLEKLGFADTAIYTTL
CCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCEEEEEEHHHHHHCCCCHHHHHHHH
ENRMKCGLGKCGRCNVGNVYVCKDGPVFTAAQVKAMPQEF
HHHHHCCCCCCCCCCCCCEEEECCCCEEEHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1704886; 11677609 [H]