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The map label for this gene is degQ [H]

Identifier: 39995191

GI number: 39995191

Start: 91907

End: 93322

Strand: Direct

Name: degQ [H]

Synonym: GSU0080

Alternate gene names: 39995191

Gene position: 91907-93322 (Clockwise)

Preceding gene: 39995189

Following gene: 39995192

Centisome position: 2.41

GC content: 63.06

Gene sequence:

>1416_bases
ATGTTCGTCCGTCGTCTGCTACTGATATCGTTGGTCTTTGTCACAACTCTCACCGCCTGCTCGAAGAAGGAAGAAAAGCT
CTTCTATGAGTCGGGCCGTGCCGACGCGCCGGTCAAGGAGGTTCCCAGAGACATCCTTGCCACCCAGCAGGCCTTCGTCG
AGCTGGTCAAGAAGGTTACTCCGTCGGTCGTGAACATCTCCACCGTCAGCCGGAGAAAGATCGAGCAGCCCTTCTTCGAG
TTTTCCCCCTTCTTCAATGATTTCTTCGACAATCGCCCCCGGTTCCGGCGGGAACAGAGCCTCGGCTCTGGCTTCATCAT
CAACCGGGAAGGGTACATCGTCACCAATGACCATGTGGTGCGCGACGCCGAAAGCATCAAGGTCAAACTCTCCAATGAGA
ACGTCTACGACGGCCACATCGTCGGCAGCGACCCCAAGACCGACATCGCGGTCATCAAGATCGACTCGCGGGAGGAACTC
CCCGTGGCGGTCCTGGCCGATTCGGACAAGCTTCAAGTGGGGCAGTGGGCGGTGGCCATCGGCAACCCCTTCGGCCTGGA
CCGGACCGTGACCGTCGGCGTGGTGTCGGCCACCGGCCGGTCCAACATGGGAATCGAGACCTATGAAGATTTCATCCAGA
CCGACGCCTCCATCAACCCGGGCAATTCGGGGGGGCCGCTGCTGAACGTCCACGGCGAGGTGATCGGCATCAACACCGCC
ATCGTGGCCGCCGGTCAGGGGATCGGCTTTGCCATCCCGGTCAACATGGCAAAGCAGATCGTAACTCAGCTCATCACCAA
GGGCAAGGTCACCCGCGGCTGGCTCGGCGTTACCATTCAACCGGTCACCGACGATCTTGCCAAGGAATTCGGCCTGAAAA
AGGCCCAGGGCGTCCTGGTGAGTGATGTGGTTAAGGGGAGCCCCGCTGCCGGCGCCGGTATCCGGCAGGGGGACATCATC
CTCAGGTTCGCCGGCAAGGAGATCAAGGATGCCCAGCACCTCCAGCGGGTGGTGGGCGACACGGCGCCGGGGACAAAGGT
GCCGGTGGTGGTCTTCCGAGAAGGGAAAGAGGTTCAACTCTCCCTGGCGACGGCCAGTTCCGACAGTGCCCAGGCACGCC
AGGCGCGCCCTCAGGGAGGGGCGCCCGACACCCTTGGCCTCGCCGTGGAGGAACTACCCCGCGAATACCGTCAGGAAGGT
TTCACCGGCGTCCTGGTGGTCCAGGTGGATGATGGGAGCGCCGCCGGCGAGGCGGGCATCCGGGAGGGGGACGTGATCGT
GGCGGTGAACCGGCGGCCCGTGGCGAACCTGGCAGAGTACGACCGCGTCATGCGCGAGGCGGCCCGGCGCGGTTCGGTAG
TGCTTCTGGTGCGACGAGGCGAGGCGAGCATCTATTTCTCCCTCAGGCTCAGGTAG

Upstream 100 bases:

>100_bases
CGGCGCCGAAAGGGCGTTGACATCCCCGGGCATATTGGCTACTCTTTCAAAGGGTTAGAGCGATCAGCTCTCATGAACCG
GTATGAGCGAGGTTCTTTGC

Downstream 100 bases:

>100_bases
CGGACTTCCGGCTCACGGGCCGGCCAACGACAGGGGACATACCATGACAATGATCGACAATCCCGACCAGGCCCGCCGCC
TTGCCCGCGCCATCATCTCG

Product: protease degQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 471; Mature: 471

Protein sequence:

>471_residues
MFVRRLLLISLVFVTTLTACSKKEEKLFYESGRADAPVKEVPRDILATQQAFVELVKKVTPSVVNISTVSRRKIEQPFFE
FSPFFNDFFDNRPRFRREQSLGSGFIINREGYIVTNDHVVRDAESIKVKLSNENVYDGHIVGSDPKTDIAVIKIDSREEL
PVAVLADSDKLQVGQWAVAIGNPFGLDRTVTVGVVSATGRSNMGIETYEDFIQTDASINPGNSGGPLLNVHGEVIGINTA
IVAAGQGIGFAIPVNMAKQIVTQLITKGKVTRGWLGVTIQPVTDDLAKEFGLKKAQGVLVSDVVKGSPAAGAGIRQGDII
LRFAGKEIKDAQHLQRVVGDTAPGTKVPVVVFREGKEVQLSLATASSDSAQARQARPQGGAPDTLGLAVEELPREYRQEG
FTGVLVVQVDDGSAAGEAGIREGDVIVAVNRRPVANLAEYDRVMREAARRGSVVLLVRRGEASIYFSLRLR

Sequences:

>Translated_471_residues
MFVRRLLLISLVFVTTLTACSKKEEKLFYESGRADAPVKEVPRDILATQQAFVELVKKVTPSVVNISTVSRRKIEQPFFE
FSPFFNDFFDNRPRFRREQSLGSGFIINREGYIVTNDHVVRDAESIKVKLSNENVYDGHIVGSDPKTDIAVIKIDSREEL
PVAVLADSDKLQVGQWAVAIGNPFGLDRTVTVGVVSATGRSNMGIETYEDFIQTDASINPGNSGGPLLNVHGEVIGINTA
IVAAGQGIGFAIPVNMAKQIVTQLITKGKVTRGWLGVTIQPVTDDLAKEFGLKKAQGVLVSDVVKGSPAAGAGIRQGDII
LRFAGKEIKDAQHLQRVVGDTAPGTKVPVVVFREGKEVQLSLATASSDSAQARQARPQGGAPDTLGLAVEELPREYRQEG
FTGVLVVQVDDGSAAGEAGIREGDVIVAVNRRPVANLAEYDRVMREAARRGSVVLLVRRGEASIYFSLRLR
>Mature_471_residues
MFVRRLLLISLVFVTTLTACSKKEEKLFYESGRADAPVKEVPRDILATQQAFVELVKKVTPSVVNISTVSRRKIEQPFFE
FSPFFNDFFDNRPRFRREQSLGSGFIINREGYIVTNDHVVRDAESIKVKLSNENVYDGHIVGSDPKTDIAVIKIDSREEL
PVAVLADSDKLQVGQWAVAIGNPFGLDRTVTVGVVSATGRSNMGIETYEDFIQTDASINPGNSGGPLLNVHGEVIGINTA
IVAAGQGIGFAIPVNMAKQIVTQLITKGKVTRGWLGVTIQPVTDDLAKEFGLKKAQGVLVSDVVKGSPAAGAGIRQGDII
LRFAGKEIKDAQHLQRVVGDTAPGTKVPVVVFREGKEVQLSLATASSDSAQARQARPQGGAPDTLGLAVEELPREYRQEG
FTGVLVVQVDDGSAAGEAGIREGDVIVAVNRRPVANLAEYDRVMREAARRGSVVLLVRRGEASIYFSLRLR

Specific function: Protease With A Shared Specificity With Degp. [C]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PDZ (DHR) domains [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=316, Percent_Identity=36.3924050632911, Blast_Score=177, Evalue=1e-44,
Organism=Homo sapiens, GI22129776, Length=311, Percent_Identity=36.9774919614148, Blast_Score=172, Evalue=5e-43,
Organism=Homo sapiens, GI24308541, Length=241, Percent_Identity=39.8340248962656, Blast_Score=161, Evalue=2e-39,
Organism=Homo sapiens, GI7019477, Length=271, Percent_Identity=36.1623616236162, Blast_Score=154, Evalue=2e-37,
Organism=Escherichia coli, GI1789629, Length=429, Percent_Identity=42.6573426573427, Blast_Score=294, Evalue=7e-81,
Organism=Escherichia coli, GI1786356, Length=446, Percent_Identity=39.0134529147982, Blast_Score=283, Evalue=2e-77,
Organism=Escherichia coli, GI1789630, Length=321, Percent_Identity=36.4485981308411, Blast_Score=194, Evalue=9e-51,
Organism=Drosophila melanogaster, GI24646839, Length=297, Percent_Identity=34.006734006734, Blast_Score=153, Evalue=2e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR011782
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.-

Molecular weight: Translated: 50991; Mature: 50991

Theoretical pI: Translated: 8.87; Mature: 8.87

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFVRRLLLISLVFVTTLTACSKKEEKLFYESGRADAPVKEVPRDILATQQAFVELVKKVT
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHC
PSVVNISTVSRRKIEQPFFEFSPFFNDFFDNRPRFRREQSLGSGFIINREGYIVTNDHVV
CCEEEEHHHHHHHHHCCHHHHCHHHHHHHCCCCHHHHHHCCCCCEEEECCCEEEECCCEE
RDAESIKVKLSNENVYDGHIVGSDPKTDIAVIKIDSREELPVAVLADSDKLQVGQWAVAI
ECCCEEEEEECCCCEECCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCEEECEEEEEE
GNPFGLDRTVTVGVVSATGRSNMGIETYEDFIQTDASINPGNSGGPLLNVHGEVIGINTA
CCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEECEE
IVAAGQGIGFAIPVNMAKQIVTQLITKGKVTRGWLGVTIQPVTDDLAKEFGLKKAQGVLV
EEEECCCCEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCCCHHCCCHH
SDVVKGSPAAGAGIRQGDIILRFAGKEIKDAQHLQRVVGDTAPGTKVPVVVFREGKEVQL
HHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEE
SLATASSDSAQARQARPQGGAPDTLGLAVEELPREYRQEGFTGVLVVQVDDGSAAGEAGI
EEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
REGDVIVAVNRRPVANLAEYDRVMREAARRGSVVLLVRRGEASIYFSLRLR
CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEEEEEC
>Mature Secondary Structure
MFVRRLLLISLVFVTTLTACSKKEEKLFYESGRADAPVKEVPRDILATQQAFVELVKKVT
CHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHC
PSVVNISTVSRRKIEQPFFEFSPFFNDFFDNRPRFRREQSLGSGFIINREGYIVTNDHVV
CCEEEEHHHHHHHHHCCHHHHCHHHHHHHCCCCHHHHHHCCCCCEEEECCCEEEECCCEE
RDAESIKVKLSNENVYDGHIVGSDPKTDIAVIKIDSREELPVAVLADSDKLQVGQWAVAI
ECCCEEEEEECCCCEECCEEECCCCCCCEEEEEECCCCCCCEEEEECCCCEEECEEEEEE
GNPFGLDRTVTVGVVSATGRSNMGIETYEDFIQTDASINPGNSGGPLLNVHGEVIGINTA
CCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHCCCCCCCCCCCCCEEEECCEEEEECEE
IVAAGQGIGFAIPVNMAKQIVTQLITKGKVTRGWLGVTIQPVTDDLAKEFGLKKAQGVLV
EEEECCCCEEEECHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHHHHHHCCCHHCCCHH
SDVVKGSPAAGAGIRQGDIILRFAGKEIKDAQHLQRVVGDTAPGTKVPVVVFREGKEVQL
HHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCCCCCCCCEEEEECCCEEEE
SLATASSDSAQARQARPQGGAPDTLGLAVEELPREYRQEGFTGVLVVQVDDGSAAGEAGI
EEEECCCCCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCC
REGDVIVAVNRRPVANLAEYDRVMREAARRGSVVLLVRRGEASIYFSLRLR
CCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCEEEEEEECCEEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362 [H]