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The map label for this gene is nisX1 [H]

Identifier: 39995159

GI number: 39995159

Start: 63072

End: 63908

Strand: Direct

Name: nisX1 [H]

Synonym: GSU0048

Alternate gene names: 39995159

Gene position: 63072-63908 (Clockwise)

Preceding gene: 39995158

Following gene: 39995160

Centisome position: 1.65

GC content: 58.42

Gene sequence:

>837_bases
GTGGGTCATTTTTCAATTTCCGATCAACCGGTAAAGTGGGTCAATTTTCGATTGCCGTTGACACCCCGGCCCACCTATTA
CCGACCACCGGCAACATGCCTGCGCGAGGGCGACCTTGTGCTGATGCGTCGCATCGACGAGCTCTATTTGGAACACCCCT
GGGCGGGCAGCAGAACGATGGCTACCTTGCTTTCCACTCCGGATGAGGTTGTCGGCCGAAAGCGGATCAGTCGCCTGATG
CGGCTGATGGGGATCGAATCGGTCGCGCCGAAACCGGGAACCAGCAAGCGCCACCCCCAGCACCCGGTCTATCCGTATCT
GTTGCGGGGCCTCGTCATCGACCGGCCCAACCAGGTCTGGGCCGCCGACGTCACCTATATCCCCATGGCCAAGGGGTTCA
TGTATCTGGTGGCCATCATGGACTGGACAACCCGGAAAGTCCTTTCCTGGCGGCTGTCTAACACCCTCGACAGCAGGTTC
TGCGTCGAGGCTCTGAATGAAGCTCTCAGCAACTTCGGCACCCCGGAGATCTTCAACACCGATCAGGGGTGCCAGTTCAC
CAGTGAAGCCTTTACCTCCGTGCTCACCGCCAACGGCATCCGGATCAGCATGGACGGCAAAGGACGCTGCCTCGACAACG
TCTTCGTCGAGCGACTGTGGCGCACTCTCAAGTACGAGAGGCTTTATCTCAAAAGCTTTGACTCCGGGATTGAACTTTCC
CGGGAGCTTTCATCCTGGTTCTCGTGGTATAACGGTGTCCGCCCTCACCAATCCCTCAAGAAGCGGACCCCGGACCAGGT
TTACTTTGCTGGACTGCCCGAGAAAAAGGCTGCCTGA

Upstream 100 bases:

>100_bases
TCAGATCAGAGGTGACAGCTACCGGCTGAAAGAGAAGCGACGCGCAGGTATTCTCGGCCAGCAACTGCCGACACCTCAGA
TCGATGACTAATCCAGGAAG

Downstream 100 bases:

>100_bases
AGCCTGTAAACCCAACAACCATGGGCCGTTGCTTAAACACCCCTTCAGGCTGTCTCACAAACCGGCACCACCTCAACCCC
AGCAGCTCTGGGCGAGTAGA

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 278; Mature: 277

Protein sequence:

>278_residues
MGHFSISDQPVKWVNFRLPLTPRPTYYRPPATCLREGDLVLMRRIDELYLEHPWAGSRTMATLLSTPDEVVGRKRISRLM
RLMGIESVAPKPGTSKRHPQHPVYPYLLRGLVIDRPNQVWAADVTYIPMAKGFMYLVAIMDWTTRKVLSWRLSNTLDSRF
CVEALNEALSNFGTPEIFNTDQGCQFTSEAFTSVLTANGIRISMDGKGRCLDNVFVERLWRTLKYERLYLKSFDSGIELS
RELSSWFSWYNGVRPHQSLKKRTPDQVYFAGLPEKKAA

Sequences:

>Translated_278_residues
MGHFSISDQPVKWVNFRLPLTPRPTYYRPPATCLREGDLVLMRRIDELYLEHPWAGSRTMATLLSTPDEVVGRKRISRLM
RLMGIESVAPKPGTSKRHPQHPVYPYLLRGLVIDRPNQVWAADVTYIPMAKGFMYLVAIMDWTTRKVLSWRLSNTLDSRF
CVEALNEALSNFGTPEIFNTDQGCQFTSEAFTSVLTANGIRISMDGKGRCLDNVFVERLWRTLKYERLYLKSFDSGIELS
RELSSWFSWYNGVRPHQSLKKRTPDQVYFAGLPEKKAA
>Mature_277_residues
GHFSISDQPVKWVNFRLPLTPRPTYYRPPATCLREGDLVLMRRIDELYLEHPWAGSRTMATLLSTPDEVVGRKRISRLMR
LMGIESVAPKPGTSKRHPQHPVYPYLLRGLVIDRPNQVWAADVTYIPMAKGFMYLVAIMDWTTRKVLSWRLSNTLDSRFC
VEALNEALSNFGTPEIFNTDQGCQFTSEAFTSVLTANGIRISMDGKGRCLDNVFVERLWRTLKYERLYLKSFDSGIELSR
ELSSWFSWYNGVRPHQSLKKRTPDQVYFAGLPEKKAA

Specific function: Involved in the transposition of the insertion sequence [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=230, Percent_Identity=29.5652173913043, Blast_Score=92, Evalue=5e-19,
Organism=Escherichia coli, GI1789981, Length=255, Percent_Identity=29.4117647058824, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1788405, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1787263, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786753, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786570, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1786490, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 32043; Mature: 31912

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGHFSISDQPVKWVNFRLPLTPRPTYYRPPATCLREGDLVLMRRIDELYLEHPWAGSRTM
CCCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCHHH
ATLLSTPDEVVGRKRISRLMRLMGIESVAPKPGTSKRHPQHPVYPYLLRGLVIDRPNQVW
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEE
AADVTYIPMAKGFMYLVAIMDWTTRKVLSWRLSNTLDSRFCVEALNEALSNFGTPEIFNT
EECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
DQGCQFTSEAFTSVLTANGIRISMDGKGRCLDNVFVERLWRTLKYERLYLKSFDSGIELS
CCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RELSSWFSWYNGVRPHQSLKKRTPDQVYFAGLPEKKAA
HHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHCCC
>Mature Secondary Structure 
GHFSISDQPVKWVNFRLPLTPRPTYYRPPATCLREGDLVLMRRIDELYLEHPWAGSRTM
CCCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCHHHHHHHHHHHHCCCCCCCHHH
ATLLSTPDEVVGRKRISRLMRLMGIESVAPKPGTSKRHPQHPVYPYLLRGLVIDRPNQVW
HHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEE
AADVTYIPMAKGFMYLVAIMDWTTRKVLSWRLSNTLDSRFCVEALNEALSNFGTPEIFNT
EECEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECC
DQGCQFTSEAFTSVLTANGIRISMDGKGRCLDNVFVERLWRTLKYERLYLKSFDSGIELS
CCCCCHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
RELSSWFSWYNGVRPHQSLKKRTPDQVYFAGLPEKKAA
HHHHHHHHHHCCCCHHHHHHHCCCCCEEECCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1482189; 11337471; 1482192 [H]