| Definition | Salmonella enterica subsp. enterica serovar Typhimurium str. LT2 chromosome, complete genome. |
|---|---|
| Accession | NC_003197 |
| Length | 4,857,432 |
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The map label for this gene is metH [H]
Identifier: 39546391
GI number: 39546391
Start: 4408339
End: 4412022
Strand: Direct
Name: metH [H]
Synonym: STM4188.S
Alternate gene names: 39546391
Gene position: 4408339-4412022 (Clockwise)
Preceding gene: 16767435
Following gene: 16767439
Centisome position: 90.75
GC content: 57.46
Gene sequence:
>3684_bases GTGAGCAGCAAAGTTGAACAACTGCGTGCGCAGTTAAATGAACGTATTCTGGTGCTGGACGGCGGTATGGGCACTATGAT CCAGAGCTATCGTCTACATGAAGAAGATTTCCGCGGGGAGCGCTTTGCCGACTGGCCCTGCGACCTGAAAGGCAACAATG ACCTGCTGGTCCTCAGCAAGCCGGAGGTGATCGCCGCTATCCACAACGCCTACTTTGAGGCTGGCGCGGATATCATCGAA ACCAACACCTTTAACTCGACAACCATTGCGATGGCGGATTACCGGATGGAATCCCTGTCGGCGGAAATTAACTATGCGGC GGCCAAACTGGCGCGCGCCTGCGCCGATGAATGGACGGCGCGAACACCAGAAAAACCACGCTTTGTTGCGGGCGTGCTTG GTCCAACTAACCGCACGGCCTCCATTTCGCCGGACGTCAACGACCCGGCGTTTCGTAATATCACCTTCGATCAGCTGGTG GCGGCCTACCGTGAATCCACCAAAGCGCTGGTGGAAGGTGGCGCAGATCTGATTCTGATTGAGACCGTTTTTGACACCCT GAATGCGAAAGCGGCGGTGTTTGCGGTGAAAGAAGAGTTTGAAGCGCTGGGCGTTGACCTGCCGATCATGATTTCCGGCA CCATCACCGACGCCTCTGGCCGTACGCTTTCCGGCCAGACTACCGAAGCCTTTTATAACTCGCTGCGCCACGCCGAGGCG CTCACTTTTGGCCTTAACTGCGCACTGGGGCCAGATGAACTGCGCCAGTACGTCCAGGAACTGTCGCGGATTGCCGAATG CTACGTCACCGCGCACCCGAACGCCGGCCTGCCGAACGCTTTCGGCGAGTATGACCTCGACGCCGACACCATGGCGAAAC AGATTCGCGAATGGGCGGAAGCGGGCTTCCTGAATATCGTTGGCGGCTGCTGCGGCACCACGCCGGAGCATATTGCGGCG ATGAGCCGCGCCGTTGCCGGTTTGCTGCCGCGCCAGCTGCCGGATATCCCGGTCGCCTGCCGCCTTTCCGGCCTGGAGCC GCTGAACATTGGCGACGATAGCCTGTTTGTGAACGTCGGCGAACGTACTAACGTCACCGGCTCGGCCAAATTTAAACGGC TGATCAAAGAAGAGAAATACAGCGAAGCGCTGGATGTCGCCCGTCAGCAGGTAGAAAGCGGCGCGCAGATTATTGATATC AATATGGATGAGGGGATGCTCGACGCCGAAGCGGCGATGGTGCGTTTCCTCAGCCTGATTGCCGGTGAGCCGGACATTGC CCGTGTACCAATCATGATCGACTCCTCCAAATGGGAGGTTATCGAAAAAGGGCTGAAGTGCATTCAGGGTAAAGGCATCG TCAACTCTATTTCGATGAAAGAGGGCGTGGAAGCCTTTATTCATCATGCGAAGCTTCTGCGTCGCTACGGCGCGGCAGTG GTGGTGATGGCCTTTGATGAGCAGGGGCAGGCCGATACCCGCGCGCGTAAAATCGAAATTTGCCGCCGAGCCTACAAAAT TCTCACCGAAGAGGTGGGTTTCCCGCCGGAAGACATCATCTTCGACCCGAATATCTTCGCCGTGGCGACCGGTATTGAAG AGCACAACAACTACGCGCAGGACTTTATCGGCGCTTGCGAAGACATCAAACGCGAGCTGCCGCACGCGCTGATCTCCGGC GGCGTGTCTAACGTGTCCTTCTCGTTCCGCGGCAACGACCCGGTACGTGAGGCTATCCACGCGGTATTCCTCTACTACGC CATCCGCAACGGTATGGACATGGGCATCGTCAACGCCGGACAGCTGGCTATCTACGACGACCTGCCCGCCGAGCTGCGCG ATGCGGTTGAAGATGTCATTCTTAACCGTCGCGATGACGGCACTGAGCGTTTGCTGGATTTGGCGGAGAAATACCGCGGC AGCAAAACCGACGAAGCTGCCAACGCCCAGCAGGCGGAATGGCGTAGCTGGGACGTGAAAAAGCGTCTCGAATACTCGCT GGTGAAAGGCATTACCGAATTTATCGAACAGGATACCGAAGAAGCCCGTCAGCAGGCCGCCCGCCCGATTGAGGTGATTG AAGGGCCGTTGATGGACGGCATGAACGTGGTCGGCGACCTGTTCGGCGAAGGGAAAATGTTCCTGCCGCAGGTGGTGAAA TCCGCTCGCGTGATGAAACAAGCGGTGGCCTACCTGGAGCCGTTTATTGAAGCCAGCAAAGAAAAAGGCTCCAGCAACGG CAAGATGGTGATCGCCACCGTGAAGGGCGATGTGCACGATATTGGTAAAAATATCGTTGGCGTGGTGCTGCAATGTAACA ACTACGAAATCGTCGATCTTGGCGTGATGGTGCCAGCGGAGAAAATCCTCAGAACGGCGCGTGAAGTGAATGCCGATCTG ATCGGTCTTTCCGGGCTGATTACCCCGTCGCTGGACGAAATGGTCAACGTGGCGAAAGAGATGGAGCGTCAGGGCTTTAC TATCCCGCTACTGATCGGCGGCGCAACCACTTCGAAAGCGCATACGGCGGTGAAAATCGAGCAGAACTACAGCGGTCCGA CGGTCTACGTGCAGAATGCTTCGCGTACCGTGGGCGTGGTGGCGGCGCTACTCTCCGACACCCAGCGTGATGACTTTGTC GCCCGTACCCGCAAAGAGTACGAAACCGTGCGTATTCAGCACGCCCGCAAAAAACCGCGCACGCCGCCGGTCACGCTGGA GGCGGCGCGCGATAACGATCTGGCATTCGATTGGGAACGCTACACCCCGCCGGTAGCCCACCGTCTGGGCGTGCAGGAGG TGGAAGCCAGCATCGAAACTCTGCGCAACTATATCGACTGGACGCCGTTCTTTATGACCTGGTCGCTGGCCGGCAAATAC CCGCGCATTCTGGAAGATGAGGTGGTGGGCGTTGAGGCGCAGCGTCTGTTTAAAGACGCCAATGATATGCTGGATAAACT GAGCGCCGAGAAACTGTTGAATCCGCGTGGCGTGGTGGGCCTGTTCCCGGCGAACCGTGTGGGTGACGACATCGAAATCT ATCGCGACGAAACCCGTACTCATGTTCTGACGGTCAGCCACCACCTGCGCCAGCAGACCGAGAAAGTCGGTTTTGCCAAC TACTGTCTGGCGGATTTTGTCGCGCCGAAACTGAGCGGCAAAGCGGATTACATCGGTGCTTTCGCGGTGACCGGCGGTCT GGAGGAGGATGCGCTGGCGGACGCCTTCGAAGCGCAACACGACGACTATAACAAGATCATGGTGAAAGCGATTGCCGACC GTCTGGCGGAAGCGTTCGCGGAATATCTGCATGAGCGTGTACGTAAGGTTTACTGGGGATATGCGCCGAACGAGAGCCTG AGTAACGACGAATTAATCCGCGAAAACTACCAGGGGATTCGCCCGGCGCCGGGTTATCCTGCCTGCCCGGAACATACCGA AAAAGGCACTATCTGGCAGCTACTGGATGTCGAAAAACACACCGGGATGAAGCTCACCGAATCTTTCGCCATGTGGCCAG GCGCGTCGGTCTCCGGCTGGTACTTCAGCCATCCTGAGAGCAAATACTTCGCGGTAGCGCAGATCCAACGCGATCAGGTG ACAGATTATGCTTTCCGTAAAGGAATGAGCGTTGAGGATGTTGAGCGGTGGCTCGCGCCGAACCTGGGTTACGATGCGGA CTGA
Upstream 100 bases:
>100_bases TGGCAAGCTGAACATGTCTCATGTTGCCCGTTGTTCTCTTTTCCGCCAGCACGCTTTGTGCCAGTATGGCTCGTTACGTG GAGCGTTGTCGGGAGCGAGT
Downstream 100 bases:
>100_bases TTCATAAAATCGTCACTTTTCCTTACAACATACAAGGCACTCATTGGGTGCCTTGTCTCTTTCTTACAATTAAACCCTTA TACTGAAGGAAGGCTCTACG
Product: B12-dependent methionine synthase
Products: NA
Alternate protein names: 5-methyltetrahydrofolate--homocysteine methyltransferase; Methionine synthase, vitamin-B12-dependent; MS [H]
Number of amino acids: Translated: 1227; Mature: 1226
Protein sequence:
>1227_residues MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIE TNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTARTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLV AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAA MSRAVAGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDI NMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISG GVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRG SKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADL IGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFV ARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFAN YCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESL SNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV TDYAFRKGMSVEDVERWLAPNLGYDAD
Sequences:
>Translated_1227_residues MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIE TNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTARTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLV AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAA MSRAVAGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDI NMDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISG GVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRG SKTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADL IGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFV ARTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFAN YCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESL SNDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV TDYAFRKGMSVEDVERWLAPNLGYDAD >Mature_1226_residues SSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIET NTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTARTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVA AYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEAL TFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAEAGFLNIVGGCCGTTPEHIAAM SRAVAGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDIN MDEGMLDAEAAMVRFLSLIAGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAVV VMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGG VSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGS KTDEAANAQQAEWRSWDVKKRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKS ARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAREVNADLI GLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVA RTRKEYETVRIQHARKKPRTPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYP RILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRTHVLTVSHHLRQQTEKVGFANY CLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLS NDELIRENYQGIRPAPGYPACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQVT DYAFRKGMSVEDVERWLAPNLGYDAD
Specific function: Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate [H]
COG id: COG1410
COG function: function code E; Methionine synthase I, cobalamin-binding domain
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 1 pterin-binding domain [H]
Homologues:
Organism=Homo sapiens, GI169790923, Length=1252, Percent_Identity=53.7539936102236, Blast_Score=1309, Evalue=0.0, Organism=Escherichia coli, GI1790450, Length=1227, Percent_Identity=96.0065199674002, Blast_Score=2428, Evalue=0.0, Organism=Escherichia coli, GI1786456, Length=329, Percent_Identity=24.3161094224924, Blast_Score=72, Evalue=2e-13, Organism=Caenorhabditis elegans, GI17535405, Length=1251, Percent_Identity=53.2374100719424, Blast_Score=1293, Evalue=0.0,
Paralogues:
None
Copy number: 513 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 1320 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR006158 - InterPro: IPR011005 - InterPro: IPR003759 - InterPro: IPR011822 - InterPro: IPR000489 - InterPro: IPR003726 - InterPro: IPR004223 [H]
Pfam domain/function: PF02310 B12-binding; PF02607 B12-binding_2; PF02965 Met_synt_B12; PF00809 Pterin_bind; PF02574 S-methyl_trans [H]
EC number: =2.1.1.13 [H]
Molecular weight: Translated: 136006; Mature: 135874
Theoretical pI: Translated: 4.69; Mature: 4.69
Prosite motif: PS50974 ADOMET_ACTIVATION ; PS50970 HCY ; PS50972 PTERIN_BINDING
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.1 %Cys (Translated Protein) 2.4 %Met (Translated Protein) 3.5 %Cys+Met (Translated Protein) 1.1 %Cys (Mature Protein) 2.4 %Met (Mature Protein) 3.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK CCHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEEEEC PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA CHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEH ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA HHHHHHHCCCHHEEHHHHHHHHHCCCCCEEEEEEEECCCCCEECCCHHHHHHHHHHHHHH LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE HHCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH AGFLNIVGGCCGTTPEHIAAMSRAVAGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEECC ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV CCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCEEEEECCHHHCCHHH DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEECCC QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVK CEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHCCCCHHHCCCCCHH KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHCHHHHHHHHHCCCCCHHHHHHH SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHEEEEEEECCEEEEEE GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA EEECCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCC HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPR EEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY CCCEEEEECCCCCCEECHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHEEECCCCE HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH EEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCC DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCC ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV CCCCCCCCCCEEEEEECHHHCCCCHHHHHHCCCCCCCCCCEECCCCCCEEEEEEHHHHHH TDYAFRKGMSVEDVERWLAPNLGYDAD HHHHHHCCCCHHHHHHHHCCCCCCCCC >Mature Secondary Structure SSKVEQLRAQLNERILVLDGGMGTMIQSYRLHEEDFRGERFADWPCDLKGNNDLLVLSK CHHHHHHHHHHCCEEEEEECCHHHHHHHHHCCHHHCCCCCCCCCCCCCCCCCCEEEEEC PEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYRMESLSAEINYAAAKLARACADEWTA CHHHHHHHHHHHHCCCCEEECCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCC RTPEKPRFVAGVLGPTNRTASISPDVNDPAFRNITFDQLVAAYRESTKALVEGGADLILI CCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEH ETVFDTLNAKAAVFAVKEEFEALGVDLPIMISGTITDASGRTLSGQTTEAFYNSLRHAEA HHHHHHHCCCHHEEHHHHHHHHHCCCCCEEEEEEEECCCCCEECCCHHHHHHHHHHHHHH LTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAGLPNAFGEYDLDADTMAKQIREWAE HHCCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHH AGFLNIVGGCCGTTPEHIAAMSRAVAGLLPRQLPDIPVACRLSGLEPLNIGDDSLFVNVG CCHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCCCCCCEEEECC ERTNVTGSAKFKRLIKEEKYSEALDVARQQVESGAQIIDINMDEGMLDAEAAMVRFLSLI CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCHHHHHHHHHHHHH AGEPDIARVPIMIDSSKWEVIEKGLKCIQGKGIVNSISMKEGVEAFIHHAKLLRRYGAAV CCCCCCEEEEEEEECCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEE VVMAFDEQGQADTRARKIEICRRAYKILTEEVGFPPEDIIFDPNIFAVATGIEEHNNYAQ EEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCCCEEEEECCHHHCCHHH DFIGACEDIKRELPHALISGGVSNVSFSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAG HHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCEECCC QLAIYDDLPAELRDAVEDVILNRRDDGTERLLDLAEKYRGSKTDEAANAQQAEWRSWDVK CEEEECCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCHHCCCCHHHCCCCCHH KRLEYSLVKGITEFIEQDTEEARQQAARPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVK HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCHHCHHHHHHHHHCCCCCHHHHHHH SARVMKQAVAYLEPFIEASKEKGSSNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDL HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHEEEEEEECCEEEEEE GVMVPAEKILRTAREVNADLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKA EEECCHHHHHHHHHHCCCCEEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEECCCCCCC HTAVKIEQNYSGPTVYVQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHARKKPR EEEEEEECCCCCCEEEEECCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCC TPPVTLEAARDNDLAFDWERYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKY CCCEEEEECCCCCCEECHHHCCCHHHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHCCCC PRILEDEVVGVEAQRLFKDANDMLDKLSAEKLLNPRGVVGLFPANRVGDDIEIYRDETRT CCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCHHEEECCCCE HVLTVSHHLRQQTEKVGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQH EEEEHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHCC DDYNKIMVKAIADRLAEAFAEYLHERVRKVYWGYAPNESLSNDELIRENYQGIRPAPGYP CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCCCCCC ACPEHTEKGTIWQLLDVEKHTGMKLTESFAMWPGASVSGWYFSHPESKYFAVAQIQRDQV CCCCCCCCCCEEEEEECHHHCCCCHHHHHHCCCCCCCCCCEECCCCCCEEEEEEHHHHHH TDYAFRKGMSVEDVERWLAPNLGYDAD HHHHHHCCCCHHHHHHHHCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 2185137; 2668277; 8369296; 8265357; 9278503; 1593636; 7992050; 8939751 [H]